Somazina Oral 500mg Solution 60ml

Introduction About SOMAZINA ORAL 500MG SOLUTION

SOMAZINA ORAL 500MG SOLUTION contains Citicoline which belongs to a group of medicines called Psychostimulants. SOMAZINA ORAL 500MG SOLUTION is used in adults to manage disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction.

SOMAZINA ORAL 500MG SOLUTION is also used to manage cognitive dysfunction that occurs due to Alzheimer’s disease (brain disease that affects memory and thinking skills) and other cerebrovascular disease. It is also indicated for use in acute and recovery phase of cerebral infarction (condition that occurs due to poor blood supply to the brain) which is also used to manage Parkinson’s disease (age related degenerative brain condition).

SOMAZINA ORAL 500MG SOLUTION is not recommended for use in patients allergic to Citicoline. It is also not recommended for use in patients suffering from hypertonia (muscle overactivity).

Before taking SOMAZINA ORAL 500MG SOLUTION, inform your doctor if you are scheduled for any surgery and/or have kidney problems (such as renal insufficiency)/liver problems (such as hepatic insufficiency).

SOMAZINA ORAL 500MG SOLUTION should be used with caution in pregnant and breastfeeding women only if necessary. It is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking SOMAZINA ORAL 500MG SOLUTION are nausea, vomiting, constipation, headache, low blood pressure and/or agitation. Consult your doctor if any of these symptoms worsens.

Uses Of SOMAZINA ORAL 500MG SOLUTION

• Manage disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction
• Manage cognitive dysfunction that occurs due to Alzheimer’s disease and other cerebrovascular disease
• Manage Parkinson’s disease
• Helps in the acute and recovery phase of cerebral infarction/ischemic stroke in affected individuals

How SOMAZINA ORAL 500MG SOLUTION Works

SOMAZINA ORAL 500MG SOLUTION works by increasing the synthesis of phosphatidylcholine (chemical that produces acetylcholine, responsible for memory and other bodily functions) which leads to improved cerebral function and cognitive function in Alzheimer’s disease and Parkinson’s disease. It also works by repairing neuronal membranes and damaged cholinergic neurons via potentiation of acetylcholine production and reduction of free fatty acid accumulation at stroke-induced nerve damage site which results in the management neuronal cell death thus helping in the recovery phase of cerebral infarction in affected individuals.

How to use SOMAZINA ORAL 500MG SOLUTION

Oral Drops:

Take SOMAZINA ORAL 500MG SOLUTION as advised by your physician. Shake well before use. Measure it with a dropper and take it as directed. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Syrup & Solution:

Take SOMAZINA ORAL 500MG SOLUTION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of SOMAZINA ORAL 500MG SOLUTION

How To Manage Side Effects

Nausea and vomiting:

Take SOMAZINA ORAL 500MG SOLUTION with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

Headache:

If SOMAZINA ORAL 500MG SOLUTION causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking SOMAZINA ORAL 500MG SOLUTION. If it lasts more than a week or severe, inform your doctor.

Warning & Precautions

Pregnancy

SOMAZINA ORAL 500MG SOLUTION should be used with caution during pregnancy only if it is clearly necessary. Consult your doctor before taking SOMAZINA ORAL 500MG SOLUTION.

Breastfeeding

SOMAZINA ORAL 500MG SOLUTION should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before taking SOMAZINA ORAL 500MG SOLUTION.

Kidney

SOMAZINA ORAL 500MG SOLUTION should be used with caution in patients with kidney problems such as kidney insufficiency. Consult your doctor before taking SOMAZINA ORAL 500MG SOLUTION.

Liver

SOMAZINA ORAL 500MG SOLUTION should be used with caution in patients with liver problems such as liver insufficiency. Consult your doctor before taking SOMAZINA ORAL 500MG SOLUTION.

Allergy

Do not take SOMAZINA ORAL 500MG SOLUTION if you are allergic to Citicoline or any of the other ingredients of this medicine.

Interactions

A.Drug - Drug interactions:

Before taking SOMAZINA ORAL 500MG SOLUTION, inform your doctor if you are taking any of the following medicine:

• levodopa (medicine used to manage Parkinson’s disease)
• meclofenoxate (used as a dietary supplement to manage dementia)

Overdosage:

If you or anyone else accidentally take too much of SOMAZINA ORAL 500MG SOLUTION, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Synopsis

More Information

• Keep SOMAZINA ORAL 500MG SOLUTION out of reach of children
• Do not store SOMAZINA ORAL 500MG SOLUTION above 30°C

FAQs About SOMAZINA ORAL 500MG SOLUTION

What is SOMAZINA ORAL 500MG SOLUTION is used for?

SOMAZINA ORAL 500MG SOLUTION is used in adults to manage disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction. It is also used to manage cognitive dysfunction that occurs due to Alzheimer’s disease (brain disease that affects memory and thinking skills) and other cerebrovascular disease. The medicine is also indicated for use in acute and recovery phase of cerebral infarction (condition that occurs due to poor blood supply to the brain) which is also used to manage Parkinson’s disease (age related degenerative brain condition) in affected individuals.

What are the side effects of SOMAZINA ORAL 500MG SOLUTION?

The most common side effects of taking SOMAZINA ORAL 500MG SOLUTION are nausea, vomiting, constipation, headache, low blood pressure and/or agitation. Consult your doctor if any of these symptoms worsens.

How SOMAZINA ORAL 500MG SOLUTION works?

SOMAZINA ORAL 500MG SOLUTION works by increasing the synthesis of phosphatidylcholine (chemical that produces acetylcholine, responsible for memory and other bodily functions) which leads to improved cerebral function and cognitive function in Alzheimer’s disease and Parkinson’s disease. It also works by repairing neuronal membranes and damaged cholinergic neurons via potentiation of acetylcholine production and reduction of free fatty acid accumulation at stroke-induced nerve damage site which results in the management neuronal cell death thus helping in the recovery phase of cerebral infarction in affected individuals.

What happens if more than required dosage of SOMAZINA ORAL 500MG SOLUTION is taken?

If you or anyone else accidentally take too much of SOMAZINA ORAL 500MG SOLUTION, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Can SOMAZINA ORAL 500MG SOLUTION be used in pregnant and breastfeeding women?

Yes, SOMAZINA ORAL 500MG SOLUTION can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before taking SOMAZINA ORAL 500MG SOLUTION.

References

1. KD. Tripathi. CNS Stimulants and Cognition Enhancers. Essentials of medical pharmacology. Seventh edition. 2013. Page - 491.

2. Cochrane Stroke Group, Arturo J Martí-Carvajal, Claudia Valli, Cristina Elena Martí-Amarista, Ivan Solà, Joan Martí-Fàbregas, Xavier Bonfill Cosp. Citicoline for treating people with acute ischemic stroke. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in August 2020] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406786/

3. Pawel Grieb. Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved Issues. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2014] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933742/

4. Antonino Maria Cotroneo, Alberto Castagna, Salvatore Putignano, Roberto Lacava, Fausto Fantò, Francesco Monteleone,5 Filomena Rocca, Alba Malara, Pietro Gareri. Effectiveness and safety of citicoline in mild vascular cognitive impairment: the IDEALE study. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2013] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569046/

5. UniLab, Inc. Citicoline. [Revised in June 2015] [Accessed on 7th May 2022] https://www.unilab.com.ph/products/cholinerv

6. Alkem Laboratories Limited. Ceham. [Accessed on 7th May 2022] https://www.alkemlabs.com/pdf/adverse/Ceham.pdf

Useful Diagnostic Tests

• Magnetic resonance imaging (MRI)
• Dopamine transporter (DAT) scan

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed For Accuracy By Dr. Aravindan Balachandran - MBBS, MD (Psychiatry)

Last updated on 25 Nov 2022 | 05:41 PM(IST)