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Introduction About SODIUM LACTATE INFUSION
SODIUM LACTATE INFUSION contains Sodium lactate which belongs to the group of medicines called Minerals and Electrolytes. SODIUM LACTATE INFUSION is used to restore fluids and salts (electrolytes) in the body when there is an acid-base imbalance or when blood is too acidic (metabolic acidosis)
SODIUM LACTATE INFUSION is also used for short term fluid replacement in case of hypovolemia (condition where liquid portion of blood is too low) or in hypotension (low blood pressure).
SODIUM LACTATE INFUSION is not recommended for use in patients allergic to Sodium chloride, Sodium lactate, Potassium chloride, and/or Calcium chloride dihydrate. It is also not recommended of use in patients suffering from extracellular hyperhydration/hypervolemia (excess fluid volume in the body), hyperkalemia (high potassium level in blood)/ hypercalcemia (high calcium level in blood), and/or metabolic alkalosis (high bicarbonate level in blood)/ severe metabolic acidosis (excess acid in the body fluids). The medicine is also not indicated for use in patients suffering from ascitic cirrhosis/severe hepatic insufficiency, severe renal insufficiency (with oliguria/anuria), and/or uncompensated cardiac failure.
Before receiving SODIUM LACTATE INFUSION, inform your doctor if you suffer from high blood levels of potassium, sodium, calcium/chloride, severe metabolic alkalosis (abnormally high levels of bases in the blood), excess water in body, and/or have heart/kidney/liver failure.
SODIUM LACTATE INFUSION should be received with caution during pregnancy only if it is necessary (especially during 3rd trimester period). It is also advised to be used with caution in breastfeeding women as it is excreted in the breastmilk.
SODIUM LACTATE INFUSION is not recommended for use in premature neonates and neonates (≤ 28 days of age) who receive ceftriaxone and is advised to be received with caution in elderly patients suffering from diseases such as heart weakness or impaired kidney function after consulting the doctor.
The most common side effects of receiving SODIUM LACTATE INFUSION are hypernatremia (high sodium level in blood) associated with signs such as muscle weakness, restlessness, extreme thirst, and metabolic alkalosis (increased bicarbonate level in blood) associated with signs such as confusion, lightheadedness, nausea, and/or vomiting. Consult your doctor if any of these symptoms worsens.
Uses Of SODIUM LACTATE INFUSION
- Helps to restore fluids and salts (electrolytes) in the body when there is an acid-base imbalance or when blood is too acidic (metabolic acidosis)
- Acts as a short-term replacement of fluids in case of hypovolemia (condition where liquid portion of blood is too low) or in hypotension (low blood pressure) in affected individuals
How SODIUM LACTATE INFUSION Works
SODIUM LACTATE INFUSION works by replacing lost body fluids and electrolytes in the body which helps to restore extracellular fluid and electrolyte balance in the body thus restoring acid-base balance and managing metabolic acidosis in affected individuals.
How to use SODIUM LACTATE INFUSION
SODIUM LACTATE INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of SODIUM LACTATE INFUSION
Common
- signs of hypernatremia (high sodium level in blood) such as muscle weakness, restlessness, and/or extreme thirst
- signs of metabolic alkalosis (increased bicarbonate level in blood) such as confusion, lightheadedness, nausea, and/or vomiting
Rare
Stop receiving SODIUM LACTATE INFUSION and contact your doctor immediately if you experience any of the following side effects:
- signs of hypersensitivity (allergic) reactions such as skin rash, itching, swelling, shortness of breath, and/or wheezing fever
Warning & Precautions
Pregnancy
SODIUM LACTATE INFUSION should be received with caution during pregnancy only if it is necessary (especially during 3rd trimester period). Consult your doctor before receiving the medicine.
Breastfeeding
SODIUM LACTATE INFUSION should be used with caution in breastfeeding women as it is excreted in the breastmilk. Consult your doctor before receiving the medicine.
Driving and Using Machines
SODIUM LACTATE INFUSION is unlikely to affect your ability to drive/operate machines. Consult your doctor before receiving the medicine.
Kidney
SODIUM LACTATE INFUSION is not recommended for use in patients with severe renal insufficiency with oliguria (low urine output) /anuria (failure of kidneys to produce urine). It should be used with caution in patients with other kidney problems such as renal failure, kidney stones. Consult your doctor before receiving the medicine.
Liver
SODIUM LACTATE INFUSION is not recommended for use in patients suffering from ascitic cirrhosis/severe hepatic insufficiency. It should be used with caution in patients with liver failure. Consult your doctor before receiving SODIUM LACTATE INFUSION.
Allergy
Do not receive SODIUM LACTATE INFUSION if you are allergic to Sodium chloride, Sodium lactate, Potassium chloride, Calcium chloride dihydrate, and/or any other ingredients of this medicine.
Lungs
SODIUM LACTATE INFUSIONshould be used with caution in patients with lung failure. Consult your doctor before receiving SODIUM LACTATE INFUSION.
Heart Disease
SODIUM LACTATE INFUSION is not recommended for use in patients with uncompensated cardiac failure. It should be used with caution in patients with heart failure. Consult your doctor before receiving SODIUM LACTATE INFUSION.
Others
SODIUM LACTATE INFUSION is not recommended for use if you:
- suffer from extracellular hyperhydration or hypervolemia (excess fluid volume in the body)
- have hyperkalemia (high potassium level in blood)
- have hypercalcemia (high calcium level in blood)
- suffer from metabolic alkalosis (high bicarbonate level in blood)
- suffer from severe metabolic acidosis (excess acid in the body fluids)
- have hyperlactatemia (metabolic disorder)/impaired lactate utilization
- suffer from water intoxication (too much water in your body).
Before receiving SODIUM LACTATE INFUSION, inform your doctor if you:
- lose water while retaining the salts
- have too high blood levels of potassium, sodium, calcium or chloride
- suffer from severe metabolic alkalosis (abnormally high levels of bases in the blood)
- suffer from excess water in body leading to peripheral oedema, extracellular hyperhydration
- have a condition where sodium gets retained such as high blood pressure, management with cortisone
- have a condition where you are retaining potassium, Ex. acute deficiency of water, extensive tissue destruction as occurs with severe burns
- suffer from a disease associated with high levels of vitamin D in blood such as sarcoidosis.
Use in Pediatrics:
SODIUM LACTATE INFUSION is not recommended for use in premature neonates and neonates (≤ 28 days of age) who receive ceftriaxone. It should be used with caution in children and adolescents (aged 2 to 18 years). Consult your doctor before receiving SODIUM LACTATE INFUSION.
Use in Geriatrics:
SODIUM LACTATE INFUSION should be used with caution in elderly patients suffering from diseases such as heart weakness or impaired kidney function. Consult your doctor before receiving the medicine.
Interactions
A. Drug - Drug interactions:
Before receiving SODIUM LACTATE INFUSION, inform your doctor if you are taking any of the following medicine:
- cortisone, carbenoxolone (to manage inflammation)
- medicines used to manage heart weakness (Ex. digitalis preparations, digoxin).
- medicines that cause an increase in serum potassium level (Ex. triamterene, amiloride, spironolactone)
- medicines used to manage high blood pressure such as ACE inhibitors (Ex. captopril, enalapril), Angiotensin II receptor antagonists (Ex. valsartan, losartan)
- medicines used to suppress immune system (Ex. tacrolimus, cyclosporine)
- suxamethonium (used to relax muscles)
- thiazide-diuretics (used for high blood pressure)
- vitamin D (used for maintaining health bones and teeth)
- medicines used to manage brittle bone disease (Ex. bisphosphonates, fluorides)
- fluoroquinolones, tetracyclines (medicines used to manage bacterial infections)
- stimulating medicinal products (Ex. ephedrine, pseudoephedrine, desamphetaminesulphate, fenfluramine hydrochloride).
- ceftriaxone (used to manage bacterial infections)
Overdosage:
SODIUM LACTATE INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms such as increased skin tension, congestion in veins, swelling of body tissues, water on the lungs/brain, disorders of fluid, salt and acid-base balance, and/or high salt levels in blood.
Synopsis
| Drug | : | Sodium Lactate |
| Pharmacological Category | : | Sodium Lactate |
| Therapeutic Indication | : | Acid-base imbalance/metabolic acidosis), Short-term replacement of fluids in case of hypovolemia/hypotension |
| Dosage Forms | : | Infusion |
More Information
- Keep SODIUM LACTATE INFUSION out of reach of children
- Do not store SODIUM LACTATE INFUSION above 25°C
FAQs About SODIUM LACTATE INFUSION
Q. What is SODIUM LACTATE INFUSION used for?
A. SODIUM LACTATE INFUSION is used to restore fluids and salts (electrolytes) in the body when there is an acid-base imbalance or when blood is too acidic. It is also used as a short-term fluid replacement when hypovolemia (condition where liquid portion of blood is too low) or hypotension (low blood pressure) occurs in affected individuals.
Q. What are the common side effects of receiving SODIUM LACTATE INFUSION?
A. The most common side effects of receiving SODIUM LACTATE INFUSION are hypernatremia (high sodium level in blood) associated with signs such as muscle weakness, restlessness, extreme thirst, and metabolic alkalosis (increased bicarbonate level in blood) associated with signs such as confusion, lightheadedness, nausea, and/or vomiting. Consult your doctor if any of these symptoms worsens.
Q. How SODIUM LACTATE INFUSION is administered?
A. SODIUM LACTATE INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q. What happens if SODIUM LACTATE INFUSION is received more than its required dosage?
A. SODIUM LACTATE INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms such as increased skin tension, congestion in veins, swelling of body tissues, pulmonary edema (excess fluid in lungs), hydrocephalus (excess cerebrospinal fluid buildup in the brain) , disorders of fluid, salt and acid-base balance, and/or high salt levels in blood.
Q. How SODIUM LACTATE INFUSION works?
A. SODIUM LACTATE INFUSION works by replacing lost body fluids and electrolytes in the body which helps to restore extracellular fluid and electrolyte balance in the body thus restoring acid-base balance and managing metabolic acidosis in affected individuals.
References
1. United States Pharmacopoeial Convention. Chemistry and Compendial Requirements. Approved drug products and Legal requirements. Edition. 2003. Page – 528.
2. Thibault Duburcq, Raphaël Favory, Daniel Mathieu, Thomas Hubert, Jacques Mangalaboyi, Valery Gmyr, Laurence Quintane, Patrice Maboudou, François Pattou, Mercé Jourdain. Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. August 2014. [Accessed on 16th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243725/
3. Albert David Limited. Sodium Lactate Injection. [Accessed on 16th August 2022] https://www.albertdavidindia.com/lvp.php
4. Baxter Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in December 2018] [Accessed on 16th August 2022] https://www.medicines.org.uk/emc/product/1812/smpc
5. B. Braun Melsungen AG. Health Products Regulatory Authority (HPRA). [Revised in June 2015] [Accessed on 16th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/PA%20179-4-8%20PIL-2165291-20072015120117-635729904787428750.pdf
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