Silorap 8mg Tablet 10'S

Introduction About SILORAP 8MG TABLET

SILORAP 8MG TABLET is a medication used for managing the symptoms of benign prostatic hyperplasia (BPH or enlared prostate) such as frequent urination, weak urine stream, difficulty starting urination, incomplete bladder emptying, urgency to urinate, straining to urinate or dribbling after urination in adults.

SILORAP 8MG TABLET is advised to take it in a dose and duration as prescribed by your doctor. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.

Before receiving SILORAP 8MG TABLET, inform your doctor if you are on any medication for any other health condition. If you have to undergo eye surgery due to cataracts or glaucoma then inform your eye doctor about the usage of this medicine. Patients with liver or kidney disease must be cautious while taking SILORAP 8MG TABLET and they must receive regular follow-ups as per the doctor’s advice.  SILORAP 8MG TABLET is not recommended for use in women, children, or adolescents under 18 years of age.

Some common side effects of this medicine are dizziness, headache, fatigue, low blood pressure (especially when standing up), abnormal ejaculation, blocked or runny nose and retrograde ejaculation. If any of the side effects persist or bother you, you must consult the doctor without delay.

Simple lifestyle changes can help you manage your symptoms better. Try to urinate as soon as you feel the urge, however, never strain or push to empty your bladder. You should avoid drinking caffeinated or alcoholic drinks at night and a few hours before going to bed or going out.

Uses Of SILORAP 8MG TABLET

• symptoms of BPH or enlarged prostate in adults only

Key Benefits of SILORAP 8MG TABLET for BPH:

In BPH, an enlarged prostate can lead to urinary issues such as frequent urination, weak urine stream, difficulty in urination, incomplete bladder emptying, etc. If left untreated, there is a risk of complete urinary blockage. SILORAP 8MG TABLET works by relaxing the muscles in the bladder and prostate, which helps to quickly relieve these symptoms and makes urination easier. To achieve the best results, take this medicine exactly as prescribed.

How SILORAP 8MG TABLET Works

SILORAP 8MG TABLET contains an active ingredient called silodosin which works by inhibiting the enzyme 5-alpha reductase. This enzyme typically converts testosterone into dihydrotestosterone (DHT), which leads to prostate enlargement. By blocking this enzyme, silodosin reduces DHT production, resulting in a decrease in prostate size and alleviating urinary symptoms associated with BPH.

How to use SILORAP 8MG TABLET

• Take SILORAP 8MG TABLET as advised by your physician.
• Swallow the medicine with a glass of water.
• Do not exceed the recommended daily dosages

Dosage instructions for BPH to get best results:

• Follow your doctor's instructions regarding the exact dosage.
• Silodosin is generally taken once a day, and it’s best to take it around the same time each day for consistency.
• It's recommended to take it with food, as this can help reduce the chances of side effects like dizziness.

Missed Dosage instructions for SILORAP 8MG TABLET:

If you miss a dose of SILORAP 8MG TABLET take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Overdosage of Silodosin:

If you or anyone else accidentally takes too much of SILORAP 8MG TABLET it may cause symptoms such as low blood pressure (hypotension), abnormal heart rhythms or tachycardia, severe dizziness, nausea and vomiting, weakness. consult your doctor immediately or visit the nearby hospital.

SILORAP 8MG TABLET: Misuse or Wrong use

• If someone takes more SILORAP 8MG TABLET than prescribed, or if the medication is taken for non-medical reasons, it is important to seek medical attention immediately.
• Overuse or incorrect usage may cause side effects such as dizziness, low blood pressure, or other adverse reactions.

Side Effects Of SILORAP 8MG TABLET

Like all medicines, SILORAP 8MG TABLET may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking SILORAP 8MG TABLET are:

• Dizziness
• Headache
• Fatigue
• Low blood pressure (especially when standing up)
• Abnormal ejaculation
• Blocked or runny nose
• Retrograde ejaculation

When to consult your doctor?

Stop taking SILORAP 8MG TABLET and consult your doctor if you experience:

• allergic reactions such as swelling of the face or throat, feeling faint, difficulty breathing, itchy skin, or hives

How To Manage Side Effects

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
• Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
• Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
• Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
• Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.

Warning & Precautions

Pregnancy

Contraindicated

Information regarding the use of Silodosin during pregnancy is not available. Also, this medicine is indicated for BPH which occurs only in men. Therefore, SILORAP 8MG TABLET is not suitable for use in pregnant women and in women who have reproductive potential.

Breastfeeding

Consult your doctor

Information regarding the use of Silodosin during breastfeeding women is not available. Hence, do no take SILORAP 8MG TABLET without physician’s advice.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel drowsiness, dizziness, or having visual disturbances after taking Silodosin.

Kidney

Monitoring required

SILORAP 8MG TABLET should be used with caution in patients having kidney disease. Dosage adjustment and careful monitoring are required in such patients. Therefore, inform your doctor if you have any pre-existing kidney diseases as a precaution.

Liver

Use with Caution

SILORAP 8MG TABLET should be used with caution in patients having severe liver disease. Regular medical check-ups and blood tests are required in such patients. Therefore, inform your doctor if you have any pre-existing liver diseases as a precaution.

Allergy

Contraindicated

Do not take SILORAP 8MG TABLET if you are allergic to Silodosin or to any of the other ingredients of this medicine.

Use In Pediatrics

Contraindicated

The safety and effectiveness of silodosin is not established in children. Therefore, SILORAP 8MG TABLET is not suitable for use in children and adolescents under 18 years of age. For more information, consult your doctor.

Use In Geriatrics

Use with Caution

SILORAP 8MG TABLET should be used with caution in elderly patients (aged 68 years or above).

Safety Advice

Expert Advice on How to Take SILORAP 8MG TABLET for BPH

1. Take Rapaflo Exactly as Prescribed

• Always follow your healthcare provider’s instructions regarding the dosage and timing. It is essential to take the medication consistently at the same time every day to maintain optimal effects.

2. Take With Food

• To improve absorption and reduce the risk of side effects like dizziness, take this medicine with food. Avoid taking it on an empty stomach as this may lead to an upset stomach or other gastrointestinal issues.

3. Monitor for Side Effects

• While this medicine is generally well-tolerated, some individuals may experience side effects such as dizziness, retrograde ejaculation, or low blood pressure. If you experience any unusual side effects or symptoms, consult your doctor immediately.

4. Regular Doctor Visits

• Regular check-ups are essential while taking SILORAP 8MG TABLET. Your healthcare provider will monitor your response to the medication and adjust the dosage if necessary to ensure maximum effectiveness in managing your BPH symptoms.

5. Avoid Sudden Position Changes

• Silodosin can cause a sudden drop in blood pressure, leading to dizziness, especially when standing up quickly. To avoid this, rise slowly from sitting or lying positions.

Interactions

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following medicine before taking SILORAP 8MG TABLET:

1.Alpha-blockers (e.g., Doxazosin, prazosin):

• Interaction: Silodosin can enhance the blood pressure-lowering effects of alpha-blockers.
• Effect: This can lead to low blood pressure, dizziness, and fainting. Blood pressure should be monitored regularly.

2. Antifungal (Ex. ketoconazole, itraconazole):

• Interaction: antifungals can increase the levels of silodosin in the bloodstream, potentially leading to an increased risk of side effects
• Effect: This can lead to low blood pressure, dizziness, and fainting. Blood pressure should be monitored regularly.

3. Protease inhibitors (Ex. ritonavir):

• Interaction: Protease inhibitors can significantly inhibit the breakdown of silodosin, leading to higher levels of silodosin in the blood.
• Effect: This can lead to low blood pressure, dizziness, and fainting. Blood pressure should be monitored regularly.

4. Immunosuppressants (Ex. ciclosporin):

• Interaction: Immunosuppressants can lead to increased levels of silodosin in the bloodstream.
• Effect: This can lead to low blood pressure, lightheadedness, dizziness, and fainting. Blood pressure should be monitored regularly.

5. Phosphodiesterase type 5 (PDE5) inhibitors (Ex. sildenafil, tadalafil):

• Interaction: PDE5 inhibitors can increase the levels of silodosin in the bloodstream, potentially leading to an increased risk of side effects
• Effect: This can lead to low blood pressure, dizziness, and fainting. Blood pressure should be monitored regularly.

6. Anticonvulsant (Ex. phenytoin):

• Interaction: Anticonvulsant can lower the blood levels of silodosin, potentially making it less effective in treating symptoms.
• Effect: This can lead to low blood pressure, dizziness, and fainting, excessive sedation, drowsiness, and other cognitive impairments. Blood pressure should be monitored regularly.

7. Cytochrome P450 Enzyme Inducers (e.g., Rifampin):

• Interaction: Some medications that induce liver enzymes may lower the levels of Silodosin in the blood.
• Effect: Reduced effectiveness of Silodosin, possibly leading to insufficient testosterone levels and less symptom relief.

Synopsis

More Information

Diet Tips to manage BPH effectively:

• • Increase Fiber Intake: Eating a high-fiber diet can help improve urinary flow and prevent constipation, which can aggravate BPH symptoms. Include whole grains, fruits, vegetables, and legumes in your diet.
  • Consume Healthy Fats: Omega-3 fatty acids (found in fatty fish like salmon, flaxseeds, and walnuts) are known to have anti-inflammatory properties and may support prostate health.
  • Limit Caffeine and Alcohol: Caffeine and alcohol can irritate the bladder and worsen urinary frequency and urgency. Reducing or eliminating them from your diet can help manage symptoms.
  • Reduce Red Meat Consumption: High-fat meats, especially red meat, may contribute to prostate health issues. Instead, focus on lean meats like chicken or plant-based protein sources.
  • Limit Salt Intake: Excessive salt can lead to fluid retention, which may exacerbate urinary symptoms. Aim for a low-sodium diet to improve overall prostate health.
  • Avoid Spicy Foods: Spicy foods can irritate the bladder, which may worsen urinary symptoms. Opt for milder alternatives to avoid bladder discomfort.

Sources: Prostate Health 10 Diet and exercise tips (health.harvard.edu)

Lifestyle Advice for BPH:

• Exercise Regularly: Regular physical activity helps maintain a healthy weight and reduces pressure on the bladder and prostate. Aim for at least 30 minutes of exercise most days of the week, including walking, swimming, or light jogging.
• Maintain a Healthy Weight: Being overweight can increase the risk of BPH progression and worsen symptoms. Focus on a balanced diet and regular exercise to manage your weight.
• Practice Bladder Training: Gradually increase the time between urinations to train your bladder. This can help reduce the frequency and urgency of urination, especially at night.
• Limit Stress: Stress can worsen urinary symptoms and overall well-being. Practice stress management techniques such as meditation, deep breathing, yoga, or mindfulness.
• Use the Bathroom Before Bed: To avoid waking up frequently at night to urinate, make sure to use the bathroom right before you go to bed.
• Quit Smoking: Smoking can irritate the bladder and worsen BPH symptoms. Quitting smoking can improve your overall health and urinary function.

Silodosin 8mg vs 4mg: Which is better for BPH?

• Both Silodosin 8mg and Silodosin 4mg are effective in treating Benign Prostatic Hyperplasia (BPH), but the right dosage depends on your doctor’s recommendation.
• Silodosin 8mg may be prescribed for patients with more severe symptoms of BPH, while the 4mg dosage is often used for those who may need a lower dose or are sensitive to the medication.
• Always follow your healthcare provider's advice regarding the correct dosage for the most effective treatment.

Is Silodosin safe for long-term use?

Yes, Silodosin is generally considered safe for long-term use when taken as prescribed for BPH. Most side effects, such as dizziness or retrograde ejaculation, are mild and manageable. However, it's essential to have regular check-ups with your doctor to monitor your health while using Silodosin, especially if you have other underlying conditions like heart problems or low blood pressure.

Silodosin vs tamsulosin for BPH treatment

• Silodosin and Tamsulosin are both alpha-blockers used to treat BPH symptoms, but they differ in their specific effects and side effects.
• Silodosin is often preferred for patients who experience significant issues with urinary flow, as it specifically targets the prostate and bladder.
• Tamsulosin, on the other hand, is widely used for its broader effect on the prostate, bladder, and urethra.
• Consult with your doctor to determine which medication is best suited for your condition.

Silodosin reviews and patient experiences:

Many Silodosin users report significant improvement in their BPH symptoms, such as reduced urinary frequency, urgency, and improved urine flow. However, some patients may experience mild side effects, like dizziness or retrograde ejaculation. Overall, Silodosin is positively reviewed for its effectiveness in managing BPH. Patient experiences highlight that the medication works quickly and with minimal discomfort, improving quality of life.

To know more, silodosin user experience (drugs.com)

Silodosin and blood pressure: Is it safe?

• Silodosin may cause a slight drop in blood pressure, especially when standing up quickly. This can lead to dizziness or lightheadedness in some patients, particularly those who are sensitive to blood pressure changes.
• If you have a history of low blood pressure or heart conditions, consult your doctor before starting Silodosin. It’s typically safe for most people, but it’s important to follow medical guidance for optimal safety.

Buy Silodosin online: Best prices and pharmacies

You can purchase Silodosin online from trusted pharmacies like Netmeds. Prices vary depending on the dosage and the pharmacy, with generic versions often being more affordable than brand-name drugs. Always check for any available discounts or coupons to get the best price on Silodosin. Make sure to buy from a reputable pharmacy to ensure the quality and authenticity of the medication.

How fast does Silodosin relieve BPH symptoms?

• Silodosin begins to show improvement in BPH symptoms like urinary frequency and urgency within 24 to 48 hours of starting the medication. Full benefits can be seen after a few weeks of consistent use.
• Patients often experience significant relief in urine flow and bladder control within the first few days of treatment, helping them return to normal daily activities.

How long do the effects of Silodosin last?

The effects of Silodosin typically last for 24 hours, which is why it is recommended to take the medication once daily. It works to relax the muscles in the prostate and bladder, which helps maintain smooth and consistent urine flow throughout the day. To maintain its effectiveness, follow the prescribed dosage and timing, and avoid missing doses.

FAQs About SILORAP 8MG TABLET

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Schwinghammer, Cecily V. DiPiro. Benign Prostatic Hyperplasia. Pharmacotherapy Handbook. Ninth Edition. 2014. Page-1455.

2. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem. Silodosin. [Accessed on 16th December 2024] click here

3. P Capogrosso, A Serino, E Ventimiglia, L Boeri, F Dehò, R Damiano, A Briganti, F Montorsi, A Salonia. Effects of silodosin on sexual function - realistic picture from the everyday clinical practice. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed.gov. Nov 2015. [Accessed on 16th December 2024] click here

4. Accord Healthcare. Health Products Regulatory Authority (HPRA). [Revised in May 2020]. [Accessed on 16th December 2024] click here

Useful Diagnostic Tests

• Prostate Specific Antigen - Psa (Total)
• Prostate Specific Antigen - Psa (Free)

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 17 Dec 2024 | 02:12 PM(IST)