Signoflam Tablet 10'S

Introduction About SIGNOFLAM TABLET

Signoflam Tablet is a combination medicine commonly used to support relief from pain and inflammation associated with everyday conditions such as muscle strain, joint discomfort, dental pain, and post-procedure swelling. It contains aceclofenac (a non-steroidal anti-inflammatory agent), paracetamol (for pain and fever control), and serratiopeptidase (an enzyme that helps reduce swelling). This combination works on multiple pathways helping to ease pain signals, reduce inflammation, and support recovery from tissue-related discomfort.

It is generally suitable for adults experiencing musculoskeletal discomfort, inflammatory conditions, or post-operative swelling, where both pain and oedema are present. Clinical use of aceclofenac-based combinations has shown effective reduction in pain intensity and improved mobility in conditions like back pain, arthritis-related discomfort, and soft tissue injuries. The addition of serratiopeptidase may further support reduction of swelling, making it a practical option when inflammation and fluid buildup are involved.

Signoflam Tablet is usually taken after food, as advised by a healthcare professional, to reduce the chance of stomach irritation. The dosage and duration should be strictly followed as prescribed, and self-medication for extended periods should be avoided. Patients should inform their doctor about any existing conditions such as stomach ulcers, liver or kidney concerns, or heart-related issues before starting the medicine. It is also important to avoid alcohol during use, as it may increase the risk of stomach discomfort.

Common side effects may include nausea, stomach discomfort, indigestion, or dizziness, which are usually mild and temporary. However, if symptoms persist or worsen, medical advice should be sought. Use during pregnancy and breastfeeding should only be considered if clearly recommended by a healthcare professional, as safety data may vary depending on individual circumstances. Overall, careful use under medical guidance can help ensure safe and effective support for pain and inflammation management.

Uses Of SIGNOFLAM TABLET

• Relief of pain and inflammation in arthritis (osteoarthritis, rheumatoid arthritis)
• Management of muscle pain, sprains, and back pain
• Relief of post-operative and dental pain
• Reduction of swellling and inflammation due to injury or trauma

Benefits of SIGNOFLAM TABLET

Signoflam Tablet for Musculoskeletal Pain

Signoflam Tablet is commonly used to support relief from musculoskeletal discomfort such as muscle pain, joint stiffness, back pain, and sprains. It works by helping to reduce inflammation and easing the sensation of pain in affected areas. This makes it useful for individuals experiencing strain due to physical activity, minor injuries, or chronic joint concerns. Regular use as advised can aid in improving mobility and overall comfort. It is important to follow the prescribed dosage to ensure safe and effective use.

Signoflam Tablet for Post-Operative Inflammation and Oedema

Signoflam Tablet may be recommended to help manage inflammation and swelling (oedema) that can occur after surgical procedures. It supports the body’s recovery process by reducing tissue inflammation and associated discomfort. This can help patients feel more comfortable during the healing phase and may assist in regaining normal function more smoothly. The medicine is usually taken for a short duration based on medical advice. Always follow your doctor’s instructions to ensure proper recovery support.

Signoflam Tablet for Fever, Headaches, and Moderate Migraines

Signoflam Tablet is also used to help manage fever, headaches, and moderate migraine episodes. It works by lowering elevated body temperature and reducing pain signals, helping individuals feel more at ease. This can be beneficial in conditions where discomfort interferes with daily activities. When taken as directed, it supports overall symptom relief and improved day-to-day functioning. It is advisable to avoid exceeding the recommended dose and consult a healthcare professional if symptoms persist.

How SIGNOFLAM TABLET Works

Mechanism of Action of Signoflam Tablet

Signoflam Tablet contains a combination of active ingredients that work together to help reduce pain and inflammation. One of its key components belongs to a group of medicines that block the production of certain chemical messengers (prostaglandins) in the body. These chemicals are responsible for causing pain, swelling, and redness at the affected site.

Another component in the tablet helps enhance the anti-inflammatory effect and supports faster reduction of swelling, especially in conditions involving tissue injury or post-surgical recovery. Together, these ingredients act at different levels to ease discomfort, improve mobility, and support overall relief. By targeting both pain signals and inflammation pathways, Signoflam Tablet provides a more comprehensive approach to managing painful conditions when used as directed.

How to use SIGNOFLAM TABLET

How to Take Signoflam Tablet

• Take the tablet as advised by a healthcare professional
• Swallow it whole with a glass of water
• Prefer taking it after food to support better comfort
• Do not crush, chew, or break the tablet
• Follow a consistent timing each day if recommended
• Continue use only for the duration advised

What if I forgot to take SIGNOFLAM TABLET

• Take the missed dose as soon as you remember
• If it is close to your next scheduled dose, skip the missed one
• Continue with your regular dosing schedule
• Do not take two tablets at the same time to make up for the missed dose

Overdose

If too much Signoflam Tablet is taken accidentally, seek medical help immediately or visit the nearest hospital. Common signs may include nausea, vomiting, stomach discomfort, dizziness, drowsiness, headache, or unusual weakness.

Side Effects Of SIGNOFLAM TABLET

How To Manage Side Effects

Constipation

• Increase Fiber Intake: Eating fibre-rich foods helps add bulk to stool and makes it easier to pass. Include fruits (like apples, papaya), vegetables, whole grains, and seeds in your daily diet. Gradually increasing fibre is important to avoid bloating.
• Drink Warm Water: Starting your day with a glass of warm water can help stimulate bowel movement. Staying well-hydrated throughout the day supports smoother digestion and stool passage.
• Take Lemon Water: Mix fresh lemon juice in warm water and drink it in the morning. It helps stimulate digestion and may support easier bowel movement.
• Eat Soaked Raisins or Figs: Soaking raisins or figs overnight and consuming them in the morning can help soften stool naturally due to their fibre content.
• Use Isabgol (Psyllium Husk): Taking a spoon of isabgol with warm water or milk at night can help regulate bowel movements by adding bulk and softness to stool.
• Include Healthy Fats: A small amount of healthy fats like ghee or olive oil in your diet may help lubricate the intestines and support easier stool passage.
• Stay Physically Active: Regular walking or light exercise helps stimulate intestinal movement and supports digestion.
• Drink Herbal Teas: Warm herbal teas like ginger or peppermint tea can help relax the digestive system and support bowel movement.
• Maintain a Routine: Try to go to the toilet at the same time every day, especially after meals. This helps train your body for regular bowel movements.
• Avoid Holding Stool: Ignoring the urge to pass stool can worsen constipation. Responding promptly helps maintain healthy bowel habits.

Warning & Precautions

Pregnancy

Contraindicated

Signoflam Tablet is generally not advised during pregnancy. It is important to consult a healthcare professional to understand its suitability based on individual health needs.

Breastfeeding

Contraindicated

Use during breastfeeding is usually not preferred, as the medicine may pass into breast milk. Seeking medical guidance is recommended before use.

Driving and Using Machines

Use with Caution

Some individuals may experience dizziness after taking this medicine. It is advisable to avoid driving or handling machinery if you do not feel fully alert.

Alcohol

Contraindicated

It is best to avoid alcohol while using Signoflam Tablet, as combining both may increase the strain on the liver.

Kidney

Contraindicated

This medicine is generally not suitable for individuals with moderate to severe kidney concerns. A healthcare professional can help assess suitability.

Liver

Consult your doctor

Caution is advised for individuals with liver-related conditions. Those with severe liver concerns may be advised to avoid this medicine, while others may require careful monitoring.

Allergy

Contraindicated

Avoid using this medicine if you have a known sensitivity to Aceclofenac, Paracetamol, Serratiopeptidase, or any of its components.

Lungs

Use with Caution

Individuals with a history of breathing-related conditions such as asthma should use this medicine carefully and seek medical advice before use.

Heart Disease

Consult your doctor

Those with existing heart-related conditions may require careful evaluation before using this medicine. A healthcare professional can guide appropriate use based on individual health status.

Use In Pediatrics

Contraindicated

Signoflam Tablet is generally not recommended for individuals below 18 years of age. Medical advice is essential before considering its use.

Use In Geriatrics

Consult your doctor

Older adults may need to use this medicine with added care. Consulting a healthcare professional can help ensure appropriate usage.

Other Warnings for SIGNOFLAM TABLET

Before taking Signoflam Tablet, inform your doctor if you

• Have uncontrolled high blood pressure
• Have diabetes
• Are a smoker
• Suffer from hyperlipidemia
• Have gastrointestinal bleeding, ulceration, or perforation
• Have gastrointestinal diseases such as ulcerative colitis (inflammatory bowel disease)
• Have systemic lupus erythematosus (autoimmune disorder)
• Have mixed connective tissue disorders such as scleroderma and polymyositis
• Have aseptic meningitis (inflammation of the brain)
• Have bleeding disorders such as hemophilia, von Willebrand disease
• Have signs of cerebrovascular bleeding, such as sudden, severe headaches or seizures
• Are on diuretic therapy

Who should not take SIGNOFLAM TABLET

Signoflam Tablet is not recommended for use if you

• Have a history of or an active, recurrent peptic ulcer or hemorrhage (bleeding)
• Have previously shown hypersensitive reactions to ibuprofen, aspirin, or other NSAIDs
• Have a previous history of an anaphylactic reaction
• Suffer from severe hypertension (high blood pressure)

Safety Advice

• Follow Prescribed Dose: Take Signoflam Tablet exactly as advised by your doctor. Avoid increasing the dose or duration on your own, as it may increase the risk of unwanted effects.
• Take with Food: It is generally recommended to take this tablet with or after food to help reduce the chances of stomach irritation.
• Use with Caution in Stomach Issues: Individuals with a history of acidity, ulcers, or digestive discomfort should use it carefully, as it may aggravate these conditions.
• Avoid Long-Term Self-Use: Do not use it for a prolonged period without medical advice. Long-term or excessive use may increase the risk of side effects.
• Check for Allergies: Do not take this medicine if you are allergic to any of its ingredients or similar medicines used for pain and inflammation.

Diet and Lifestyle Advice

• Take a Balanced Diet: Include fresh fruits, vegetables, whole grains, and protein-rich foods in your meals. A balanced diet supports recovery and helps the body respond better to pain and inflammation.
• Prefer Light and Non-Spicy Foods: Since this medicine may sometimes cause stomach irritation, choose light, less oily, and less spicy foods to keep your digestion comfortable.
• Stay Well Hydrated: Drink plenty of water throughout the day. Proper hydration supports overall body function and may help reduce discomfort related to inflammation.
• Include Anti-Inflammatory Foods: Add foods like turmeric, ginger, nuts, and green leafy vegetables to your diet. These may help support the body’s natural response to inflammation.
• Avoid Skipping Meals: Take the tablet after food and avoid long gaps between meals to reduce the risk of acidity or stomach discomfort.
• Maintain Healthy Body Weight: Keeping a healthy weight can reduce stress on joints and muscles, especially in conditions involving pain or inflammation.
• Stay Physically Active: Engage in light activities like walking, stretching, or yoga to support mobility and reduce stiffness. Avoid excessive strain on painful areas.
• Ensure Proper Rest: Adequate rest is important for recovery, especially if the medicine is being used for injury or post-operative discomfort.
• Practice Good Posture: Maintaining correct posture while sitting, standing, or lifting objects can help reduce musculoskeletal strain and improve comfort.
• Take a Balanced Diet: Include fresh fruits, vegetables, whole grains, and protein-rich foods in your meals. A balanced diet supports recovery and helps the body respond better to pain and inflammation.
• Prefer Light and Non-Spicy Foods: Since this medicine may sometimes cause stomach irritation, choose light, less oily, and less spicy foods to keep your digestion comfortable.
• Stay Well Hydrated: Drink plenty of water throughout the day. Proper hydration supports overall body function and may help reduce discomfort related to inflammation.
• Include Anti-Inflammatory Foods: Add foods like turmeric, ginger, nuts, and green leafy vegetables to your diet. These may help support the body’s natural response to inflammation.
• Avoid Skipping Meals: Take the tablet after food and avoid long gaps between meals to reduce the risk of acidity or stomach discomfort.
• Maintain Healthy Body Weight: Keeping a healthy weight can reduce stress on joints and muscles, especially in conditions involving pain or inflammation.
• Stay Physically Active: Engage in light activities like walking, stretching, or yoga to support mobility and reduce stiffness. Avoid excessive strain on painful areas.
• Ensure Proper Rest: Adequate rest is important for recovery, especially if the medicine is being used for injury or post-operative discomfort.
• Practice Good Posture: Maintaining correct posture while sitting, standing, or lifting objects can help reduce musculoskeletal strain and improve comfort.

1. Signoflam Tablet vs Hifenac Tablet - musculoskeletal discomfort

Drug - Drug interaction

1. Blood Thinners (e.g., Warfarin, Aspirin)

• Interaction: May increase the risk of bleeding when used together.
• Management: Regular monitoring may be required, and dose adjustments may be considered by your doctor.

2. Other Pain-Relieving Medicines (NSAIDs)

• Interaction: Combining with similar medicines may increase the risk of stomach irritation and related discomfort.
• Management: Avoid using multiple pain-relieving medicines together unless advised by a healthcare professional.

3. Corticosteroids (e.g., Prednisolone)

• Interaction: May increase the chances of stomach-related irritation when taken together.
• Management: Use cautiously and follow medical advice for safe combination use.

4. Blood Pressure Medicines (e.g., ACE inhibitors, Diuretics)

• Interaction: May reduce the effectiveness of blood pressure control in some individuals.
• Management: Blood pressure may need to be monitored regularly during combined use.

5. Methotrexate

• Interaction: May increase the levels of methotrexate in the body, leading to higher risk of adverse effects.
• Management: Close medical supervision and possible dose adjustment are required.

6. Lithium

• Interaction: May increase lithium levels in the blood, which can affect its safety profile.
• Management: Monitoring of lithium levels is recommended if used together.

7. Certain Antibiotics (e.g., Quinolones)

• Interaction: May increase the risk of nervous system-related effects in some individuals.
• Management: Use under medical supervision with appropriate monitoring.

8. Anti-diabetic Medicines

• Interaction: May influence blood sugar levels in some cases.
• Management: Regular blood glucose monitoring may be advised.

9. Diuretics (Water Tablets)

• Interaction: May reduce the effectiveness of diuretics and affect kidney function.
• Management: Adequate hydration and monitoring of kidney function may be required.

Drug - Food interaction

1. High-Fat or Heavy Meals

• Interaction: Very heavy or fatty meals may slow down the absorption of the medicine, which can delay its onset of action.
• Management: Prefer taking the tablet after a light or regular meal for better consistency.

2. Caffeine-Containing Beverages (Tea, Coffee, Energy Drinks)

• Interaction: Excess caffeine intake may increase restlessness or discomfort in some individuals when combined with this medicine.
• Management: Moderate consumption of caffeinated drinks is recommended.

3. Herbal Supplements and Natural Products

• Interaction: Certain herbal products (such as those affecting blood flow or liver function) may influence how the medicine works in the body.
• Management: Inform your healthcare professional about any supplements you are taking before use.

4. Spicy and Irritating Foods

• Interaction: Spicy or oily foods may increase stomach discomfort in some individuals when taken along with this medicine.
• Management: Opt for a balanced, mild diet during use to support better tolerance.

Synopsis

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FAQs About SIGNOFLAM TABLET

References

1. KD. Tripathi. Aspects of Pharmacotherapy, Clinical Pharmacology and Drug Development, and Nonsteroidal Anti-Inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 71, 204 & 206.

2. Manju Tiwari. The role of serratiopeptidase in the resolution of inflammation. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. [Revised in 1st February 2017] [Accessed on 17th March 2026] 

3. Ciplamed. MOVEXX SP Tablets [Accessed on 17th March 2026] 

4. Narankaa Pharma. ACEDUOZ. [Accessed on 17th March 2026] 

5. Aden Healthcare. Kedac SP. [Accessed on 17th March 2026] 

Useful Diagnostic Tests

• Basic Arthritis Care
• Extended Arthritis Care
• Comprehensive Arthritis Care
• Complete Blood Count (CBC)/ Hemogram
• Esr Automated
• Advanced Arthritis Care
• Autoimmune Arthritis Panel