SICOR COLD TABLET 10'S
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Introduction About SICOR COLD
SICOR COLD is a combination of Caffeine, Chlorpheniramine, Paracetamol and Phenylephrine, which belongs to the group of medicines called Central nervous system stimulants, Antihistamines, Analgesics and nasal decongestants respectively. It is used in the management of the common cold and flu to provide relief from fever, nasal congestion, headache, pain and symptoms of the nose or throat due to upper respiratory tract allergies. It is also used in bacterial infections such as sinusitis, tonsillitis and otitis media, along with other medicines.
While taking SICOR COLD, avoid alcohol, coffee, strong tea and other tonic drinks. SICOR COLD is not recommended for use in patients with asthma, severely impaired liver or kidney function, severe hypertension, heart diseases, closed-angle glaucoma, an adrenal gland tumour (Pheochromocytoma), hyperthyroidism, diabetes, porphyria, peptic ulcer or hyperplasia of the prostate gland.
SICOR COLD is also not recommended for use in pregnant women, breastfeeding women or children below 12 years of age. In elderly patients, SICOR COLD should be used with caution. The common side effects of SICOR COLD are nausea and vomiting, drowsiness, insomnia, dizziness, headache and nervousness. If any of these become worse, contact your doctor.
Uses Of SICOR COLD
Manages the following conditions in adults and children (6 to12 years of age):
- Common cold and flu to provide relief from fever, nasal congestion, headache and pain
- Allergic symptoms of the nose or throat due to upper respiratory tract allergies
- Bacterial infections such as sinusitis, tonsillitis and otitis media along with other medicines
How SICOR COLD Works
[GBNKWEYORD] is a combination of medicines, where Paracetamol works by elevating the pain threshold and acting on the heat-regulating centre in the brain to reduce pain and fever; Phenylephrine works by reducing swelling of the blood vessels in the nasal passages; Chlorpheniramine reduces the effects of the natural chemical histamine in the body and Caffeine enhances the activity of Paracetamol and reduces drowsiness due to Chlorpheniramine. This collective collection provides relief from fever, nasal congestion, runny nose, sneezing, headache and pain.
How to use SICOR COLD
Take SICOR COLD as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your doctor, depending on your age, body weight and disease condition. Do not stop taking SICOR COLD unless your doctor advises you to stop.
Side Effects Of SICOR COLD
Common
- nausea and vomiting
- drowsiness and excessive sleepiness
- dizziness
- headache
- nervousness
- difficulty in falling asleep
- increased blood pressure
Uncommon
- restlessness
- anxiety, irritability
- feeling that heart is racing or skipping a beat
Rare
- easy or excessive bruising along with tiredness and blood in urine or stools (signs of thrombocytopenia)
- fever, chills, weakness, sudden low blood pressure, bleeding gums and breathing problems (signs of agranulocytosis)
Stop taking SICOR COLD and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction signs (skin rash, itching, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath)
How To Manage Side Effects
Nausea or vomiting:
Take SICOR COLD with or just after meals, along with your medication. Stick to simple meals and avoid eating oily or spicy foods. If there is no improvement, contact your doctor for advice.
Headache:
Try to relax and rest yourself. Apply pain balm to the head to ease the pain. Sip on some hot water or ginger tea. If there is no improvement, contact your doctor for advice.
Dizziness:
Sit down or lie down slowly when you are feeling dizzy. Take some time to rest and drink plenty of water. Avoid coffee and other carbonated drinks. If there is no improvement, contact your doctor for advice.
Warning & Precautions
Pregnancy
SICOR COLD is generally not recommended for use in pregnant women. Consult your doctor for advice.
Breastfeeding
SICOR COLD is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor for advice.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy, drowsy or blurred vision after taking SICOR COLD.
Alcohol
Avoid consumption of alcohol while taking SICOR COLD because it might make you drowsier and impairs your concentration.
Kidney
SICOR COLD is not recommended for use in patients with severely impaired kidney function. Consult your doctor for advice.
Liver
SICOR COLD is not recommended for use in patients with severely impaired liver function. Consult your doctor for advice.
Allergy
Do not take SICOR COLD if you are allergic to Caffeine, Chlorpheniramine, Paracetamol and Phenylephrine.
Lungs
SICOR COLD is not recommended for use in patients with asthma. Consult your doctor for advice.
Heart Disease
SICOR COLD is not recommended for use in patients with severe hypertension, coronary heart disease and cardiovascular disorders. Consult your doctor for advice.
Others
SICOR COLD is not recommended for use if you:
- have closed-angle glaucoma
- have adrenal gland tumour (Pheochromocytoma)
- have hyperthyroidism
- have diabetes
- have porphyria
- have peptic ulcer
- have hyperplasia of the prostate gland, bladder neck obstruction and pyloroduodenal obstruction
Before taking SICOR COLD, inform your doctor if you:
- are an athlete going for doping tests
- have Raynaud’s phenomenon
- have epilepsy
Use in Pediatrics:
SICOR COLD is generally not recommended for use in children under 12 years of age. Consult your doctor for advice.
Use in Geriatrics:
SICOR COLD should be used with caution in elderly patients. Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before taking SICOR COLD, inform your doctor if you are taking any of the following medicine:
- medicines used in depression management [ex. isocarboxazid, phenelzine, amitriptyline]
- brompheniramine, benzphetamine, ephedrine (other medicines used for nasal congestion, allergic shock and heart failure)
- digoxin (a medicine used in the management of heart diseases)
- phenytoin (a medicine used in epilepsy management)
- zolpidem, flurazepam, suvorexant, butabarbital and triazolam (medicines used for sleep disorders)
- ergotamine and methysergide (medicines used to manage severe, throbbing headaches, such as migraine and cluster headaches)
- medicines used to control blood pressure (ex. reserpine, methyldopa, debrisoquine, atenolol and propranolol)
- warfarin and dicumarol sodium (medicines used to manage blood clotting)
B. Drug - Food interaction:
Avoid taking coffee, strong tea and other tonic drinks while taking SICOR COLD.
Overdosage:
If you or anyone else accidentally take too much of SICOR COLD, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are pallor, nausea, vomiting, anorexia, abdominal pain, vomiting, excessive urination, tachycardia, insomnia, restlessness, excitement, agitation, jitteriness, tremors and convulsions.
Synopsis
| Drug | : | Caffeine, Chlorpheniramine, Paracetamol, Phenylephrine |
| Pharmacological Category | : | Methylxanthines, Antihistamines, Analgesics, Adrenergic agonists |
| Therapeutic Indication | : | Common cold, flu, sinus headache, throat and ear infections |
| Dosage Forms | : | Tablet |
More Information
- Keep SICOR COLD out of reach from children
- Store at room temperature
FAQs About SICOR COLD
Q: What is SICOR COLD used for?
A: SICOR COLD temporarily manages symptoms caused by the common cold, flu, allergies or other breathing illnesses (such as sinusitis and bronchitis). It also helps relieve stuffy nose, sinus and ear congestion symptoms.
Q: Is SICOR COLD suitable for cold weather?
A: SICOR COLD contains medicines that manage headache, fever, body aches, a runny or stuffy nose, sneezing, itching, watery eyes and sinus congestion caused by allergies, the common cold or the flu. Always take the medicine after consulting a doctor.
Q: Can SICOR COLD cause high BP?
A: SICOR COLD can cause severe hypertensive episodes leading to intracranial haemorrhage in the case of overdosage. Always inform patients about the dangers of exceeding the recommended dose and the increased risk of serious adverse effects such as hypertensive crises.
Q: Does SICOR COLD affect the kidney?
A: SICOR COLD can cause irreversible kidney damage if used for a prolonged period. Thus, it is not recommended for use in patients with severely impaired kidney function. You should always consult a doctor before taking the medicine.
Q: Can we take SICOR COLD and cetirizine together?
A: Using SICOR COLD together with Cetirizine may increase side effects such as dizziness, drowsiness and difficulty concentrating. Some people, especially the elderly, may also experience impaired thinking, confusion and problems in motor coordination.
References
1. KD Tripathi. Drugs acting on the Autonomic nervous system, Autacoids and related drugs, Essentials of medical pharmacology. Eighth edition. 2019. Page – 245, 179, 153, 223.
2. Abdulbari, M. M. and M. S. Ihsan. Simultaneous determination and validation of chlorpheniramine maleate, acetaminophen, phenylpropanolamine hydrochloride and caffeine in tablet dosage form by using reverse-phase high-performance liquid chromatography. [Revised in July 2013] [Accessed on 20th June 2022] https://asset-pdf.scinapse.io/prod/2186195757/2186195757.pdf
3. Saga Laboratories. COL-COL. https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/Jan_2022/COL-COL-Tablet-SmPC.pdf
4. Centaurpharma.Sinarest Tablet. https://www.centaurpharma.com/downloads/Sinarest%20Tab.pdf
Useful Diagnostic Tests
- Liver function tests
- Fasting blood sugar level
- Random blood sugar level
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