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Introduction About SIBOFIX SUSPENSION
SIBOFIX SUSPENSION is used in adults and in children (aged 2 years or above) to manage infectious diarrhea. It contains Rifaximin which belongs to the group of medicines called Antibiotics which works against the susceptible bacteria that causes infection by blocking the actions of certain enzymes in the bacteria that is required for its survival. As a result, it stops the growth and multiplication of the harmful bacteria in the gut and controls diarrhea.
Take SIBOFIX SUSPENSION for the stipulated duration instructed by your doctor even if you feel better during the midway of the therapy. Inform your doctor if you can’t notice any improvement in your condition or if you feel worse after 3 days of therapy. It is not recommended for use in patients with bloody diarrhea or diarrhea accompanied by fever and in patients passing unformed (soft or liquid) stools for more than 8 times a day. It is also not suitable for use in patients having any stomach problems (such as constipation, vomiting, or stomach pain due to blockage in the gut).
Inform your doctor before taking SIBOFIX SUSPENSION if you are pregnant, think you may be pregnant or breastfeeding women. This medicine may cause pink or reddish discoloration of urine. This usually disappears after discontinuation of the therapy. The most common side effects of taking headache, flatulence, stomach pain, constipation, urge to empty bowels and fever. Contact your doctor if any of these side effect worsens.
Uses Of SIBOFIX SUSPENSION
- Used to manage infectious diarrhea in adults and in children (aged 2 years or older)
How SIBOFIX SUSPENSION Works
SIBOFIX SUSPENSION is an intestinal antibiotic which works against the susceptible bacteria by blocking the actions of certain enzymes (bacterial DNA-dependent RNA polymerase) in the bacteria that is required for its survival. As a result, it stops the growth and multiplication of harmful bacteria in the gut and controls diarrhea.
How to use SIBOFIX SUSPENSION
- Take SIBOFIX SUSPENSION as advised by your physician
- Shake well before use
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection
- Do not stop taking the medicine even if you feel better during the midway of the therapy, as it may worsen your condition
Side Effects Of SIBOFIX SUSPENSION
Common side effects of SIBOFIX SUSPENSION:
- flatulence, stomach pain, constipation, diarrhea
- urgency to empty bowels
- involuntary and painful or ineffective straining
- fever
- loss of appetite
- changes in taste
- muscle pain, weakness or cramps, neck pain
Stop taking SIBOFIX SUSPENSION and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction (such as skin rash, itching, shortness of breath, wheezing, rapid heartbeat, swelling of the mouth, face, ankles or any other part of the body, extreme tiredness, dizziness or feeling faint)
- severe uncontrollable diarrhea
- bloody urine or red discoloration of urine
Warning & Precautions
Pregnancy
Consult your doctorSIBOFIX SUSPENSION is not recommended for use in pregnant women unless considered clearly necessary by the physician.
Breastfeeding
Use with CautionSIBOFIX SUSPENSION should be used with caution in breastfeeding women.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or drowsy after taking SIBOFIX SUSPENSION.
Allergy
ContraindicatedDo not take SIBOFIX SUSPENSION if you are allergic to Rifaximin or to any other ingredients of this medicine.
Use In Pediatrics
Monitoring requiredSIBOFIX SUSPENSION should be used in children (aged 2 years or above) only if prescribed by the physician.
Use In Geriatrics
Use with CautionSIBOFIX SUSPENSION should be used with caution in elderly patients (aged 65 years or above).
Others
It is not recommended for use if you have:
- a blockage in your intestine (causing constipation, stomach pain, and vomiting)
- fever
- bloody stools
- passed 8 or more unformed stools in the last 24 hours
Interactions
A. Drug-Drug Interaction:
Before taking SIBOFIX SUSPENSION, inform your doctor if you are taking any of the following:
- immunosuppressants (Ex. cyclosporin)
- anticoagulants (Ex. warfarin)
- oral contraceptives (Ex. drospirenone, ethinyl estradiol)
- activated charcoal
Overdosage:
If you or anyone else accidentally took more of SIBOFIX SUSPENSION, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Rifaximin |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Infectious Diarrhoea |
| Dosage Forms | : | Tablet, Syrup, Suspension |
More Information
Storage
- Keep out of reach of children
- Store SIBOFIX SUSPENSION at room temperature
FAQs About SIBOFIX SUSPENSION
Q: Can I stop taking SIBOFIX SUSPENSION suddenly?
A: No. Do not stop taking SIBOFIX SUSPENSION even if you feel better during the midway of the therapy, as it may worsen your condition. Take the medicine for the stipulated duration instructed by your doctor. Also, inform your doctor if you can’t notice any improvement in your condition or if you feel worse after 3 days of therapy.
Q: Can SIBOFIX SUSPENSION cause headache?
A: Yes. It may cause headache in some individuals. If you experience headache, try to rest, and relax. Apply a pain-relieving balm on your forehead to ease off the pain. Sip some hot water or ginger tea. If there is no improvement in your condition, contact your doctor.
Q: Can I take SIBOFIX SUSPENSION during pregnancy?
A: SIBOFIX SUSPENSION is generally not recommended for use in pregnant women unless considered clearly necessary by the physician.
Q: Can SIBOFIX SUSPENSION be used in children?
A: SIBOFIX SUSPENSION can be used in children (aged 2 years or above). However, it should be used only if prescribed by the physician.
Q: How long should I SIBOFIX SUSPENSION be taken?
A: Take SIBOFIX SUSPENSION as advised by your physician. It is usually prescribed for 3 days. However, consult your doctor regarding the duration of therapy. Do not stop taking the medicine even if you feel better during the midway of the therapy, as it may worsen your condition. Inform your doctor if there is no improvement in your condition after 3 days of therapy.
Q: Is SIBOFIX SUSPENSION a strong antibiotic?
A: Yes. It is a potent antibiotic with bactericidal and bacteriostatic effects. It can effectively works against the bacteria and manages their multiplication within our body.
Q: What is SIBOFIX SUSPENSION used for?
A: SIBOFIX SUSPENSION is an intestinal antibiotic used to manage diarrhoea caused due to intestinal infections which works against the disease-causing germs and manages their multiplication within our body which helps in controlling infections.
Q: Can the use of SIBOFIX SUSPENSION cause red urine?
A: Yes. It may cause pink or reddish discoloration of urine. This usually disappears after stopping the therapy.
Q: How to take SIBOFIX SUSPENSION?
A: Take SIBOFIX SUSPENSION as advised by your physician. Shake well before use. Continue to take medicine for the stipulated duration instructed by your doctor even if you feel better during the midway of the therapy. Do not stop taking the medicine without consulting your doctor, as it may worsen your condition.
Q: Can SIBOFIX SUSPENSION be used for liver infection?
A: Consult your doctor before using the medicine to manage liver infections. Your doctor might prescribe a higher dose of rifaximin to manage liver infections.
References
1. KD. Tripathi. Drugs for constipation and diarrhoea. Essentials of Pharmacology. Seventh edition. 2013. Page – 681.
2. Cober, Mary Petrea, Cary E. Johnson, Jordan Lee, and Kenne Currie. Stability of extemporaneously prepared rifaximin oral suspensions. American Journal of Health-System Pharmacy. [Revised in February 2010] [Accessed on 3rd June 2022] click here
3. Alfasigma S.p.A. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on 2nd June 2022] click here
4. Central Drugs Standard Control Organization. Rifaximin Oral Suspension 100mg/5ml (New Dosage Form). June 2011. [Accessed on 14th July 2022] click here
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