Scabimide P Lotion 50ml

Introduction About SCABIMIDE P LOTION

SCABIMIDE P LOTION contains Gamma benzene hexachloride, which belongs to a group of medicines called Ectoparasiticides. SCABIMIDE P LOTION is used to manage scabies (itchy skin rash caused by burrowing mite) in patients who are intolerant/had failed management with other approved therapies to manage the condition.

SCABIMIDE P LOTION is not recommended for use in patients allergic to Gamma benzene hexachloride. It is also not recommended for use in patients suffering from crusted scabies, second scabies attack, skin conditions (such as atopic dermatitis, psoriasis), and/or uncontrolled seizure disorders.

Before applying SCABIMIDE P LOTION, inform your doctor if you have/had head injury, brain/spinal cord tumour, HIV/AIDS, and/or liver problems (such as severe hepatic cirrhosis).

SCABIMIDE P LOTION should be used with caution in pregnant women only if it is clearly necessary. It is not recommended for use in breastfeeding women unless it is clearly necessary.

SCABIMIDE P LOTION is advised to be used with caution in children and adolescents (aged below 18 years) who weigh less than 50 kg (110 pounds) and is also advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.

The most common side effects of applying SCABIMIDE P LOTION are itching skin, burning skin, dry skin, and/or skin rash. Consult your doctor if any of these symptoms worsen.

Uses Of SCABIMIDE P LOTION

• Manage scabies in patients who are intolerant/had failed management with other approved therapies.

How SCABIMIDE P LOTION Works

SCABIMIDE P LOTION works by blocking the action of the GABA-gated chloride channel (neurotransmitter) in parasites, which leads to low neuronal inhibition and paralysis in parasites, thus resulting in its destruction and providing relief from skin disease caused by parasites (scabies) in affected individuals.

How to use SCABIMIDE P LOTION

Always apply SCABIMIDE P LOTION as directed by your physician. It is for external use only. Shake well before use. Apply a thin layer of this medicine to the affected area. Managed areas should not be covered with a plaster or bandage. Following application, wash the applied area after 8 to 12 hours. The medicine should be washed off completely. Avoid using the medicine again after the first application and throw away the bottle after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects Of SCABIMIDE P LOTION

How To Manage Side Effects

Dry Skin

Try moisturizing your skin with an ointment, cream, or lotion 2 or 3 times a day, or as often as needed. Moisturizers help to keep the area moist, so they work best on damp skin. After you bathe, pat your skin dry and apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, and/or other chemicals.

Skin rash Or Itching

Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants, or moisturizers, and use a skin softener regularly.

Warning & Precautions

Pregnancy

Monitoring required

SCABIMIDE P LOTION should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying the medicine.

Breastfeeding

Monitoring required

SCABIMIDE P LOTION is not recommended for use in breastfeeding women unless it is clearly necessary. Application to the breast area is advised to be avoided to manage accidental ingestion by the breastfed baby. Consult your doctor before applying the medicine.

Alcohol

Contraindicated

Avoid consumption of alcohol while using SCABIMIDE P LOTION since it may increase the risk of getting a seizure.

Liver

Use with Caution

SCABIMIDE P LOTION should be used with caution in patients with liver problems such as severe hepatic cirrhosis. Consult your doctor before applying the medicine.

Allergy

Contraindicated

Do not apply SCABIMIDE P LOTION if you are allergic to Gamma Benzene Hexachloride and/or any other ingredients of this medicine.

Use In Pediatrics

Use with Caution

SCABIMIDE P LOTION should be used with caution in children and adolescents (aged below 18 years) who weigh less than 50 kg (110 pounds). Consult your doctor before applying this medicine.

Use In Geriatrics

Use with Caution

SCABIMIDE P LOTION should be used with caution in elderly patients (aged 65 years or older). Consult your doctor before applying this medicine.

Interactions

A. Drug-drug interactions:

Before applying SCABIMIDE P LOTION, inform your doctor if you are taking any of the following medicines:

• Sedatives (used to manage anxiety, tension, seizures, pain, and sleep disorders) Ex. barbiturates, benzodiazepines
• Antipsychotics (used to manage psychosis) Ex. amisulpride, asenapine
• Antidepressants (used to manage depression) Ex. fluoxetine, paroxetine
• Theophylline (used to manage asthma and bronchitis)
• Cyclosporin, mycophenolate mofetil (used to manage organ rejection after transplant)
• Tacrolimus (used to manage moderate to severe atopic dermatitis)
• Penicillin, imipenem, and quinolone (used to manage bacterial infections)
• Chloroquine sulfate (used to manage malaria)
• Isoniazid (used to manage tuberculosis)
• Meperidine (used to relieve pain)
• Methocarbamol (used to manage acute musculoskeletal pain)

Overdosage:

If you or anyone else applies too much of SCABIMIDE P LOTION or accidentally swallows it, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Synopsis

More Information

FAQs About SCABIMIDE P LOTION

Q: What is SCABIMIDE P LOTION used for?

A: SCABIMIDE P LOTION is used to manage scabies (itchy skin rash caused by burrowing mite) in patients who are intolerant/had failed management with other approved therapies to manage the condition.

Q: What are the common side effects of SCABIMIDE P LOTION?

A: The most common side effects of applying SCABIMIDE P LOTION are itching skin, burning skin, dry skin, and/or skin rash. Consult your doctor if any of these symptoms worsen.

Q: How SCABIMIDE P LOTION works?

A: SCABIMIDE P LOTION works by blocking the action of the GABA-gated chloride channel (neurotransmitter) in parasites, which leads to low neuronal inhibition and paralysis in parasites, thus resulting in its destruction and providing relief from skin disease caused by parasites (scabies) in affected individuals.

Q: How to use SCABIMIDE P LOTION?

A: Always apply SCABIMIDE P LOTION as directed by your physician. It is for external use only. Shake well before use. Apply a thin layer of this medicine to the affected area. Managed areas should not be covered with a plaster or bandage. Following application, wash the applied area after 8 to 12 hours. The medicine should be washed off completely. Avoid using the medicine again after the first application and throw away the bottle after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q: Does SCABIMIDE P LOTION cause itching?

A: Yes, SCABIMIDE P LOTION causes itchy skin, as it is the most common side effect associated with the use of SCABIMIDE P LOTION. If such side effect is experienced, then try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants, or moisturizers, and use a skin softener regularly to reduce itchiness of the skin.

Q: Is SCABIMIDE P LOTION safe during pregnancy?

A: SCABIMIDE P LOTION should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying the medicine.

Q: Who should not use SCABIMIDE P LOTION?

A: SCABIMIDE P LOTION is not recommended for use if you have crusted scabies, suffer from a second attack of scabies, have skin conditions such as atopic dermatitis, psoriasis, uncontrolled seizure disorders, or have head/body lice and are allergic to Gamma Benzene Hexachloride.

Q: What precautions must be taken while using SCABIMIDE P LOTION?

A: Before applying SCABIMIDE P LOTION, inform your doctor if you have/had a head injury, brain/spinal cord tumour, suffer from HIV/AIDS, or have liver problems such as severe hepatic cirrhosis.

Q: Can SCABIMIDE P LOTION be used in children?

A: SCABIMIDE P LOTION should be used with caution in children and adolescents (aged below 18 years) who weigh less than 50 kg (110 pounds). Consult your doctor before applying this medicine.

Q: Can I use SCABIMIDE P LOTION every day?

A: Always use SCABIMIDE P LOTION as advised by your doctor. Do not use it more often, and do not use it for a longer time than your doctor ordered. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

References

1. KD Tripathi. Antiseptics, Disinfectants, and Ectoparasiticides. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 903.

2. Jodi Raffi, Raagini Suresh, Daniel C. Butler. Review of Scabies in the Elderly. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. September 2019.  [Accessed on 1st August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828878/

3. Lindane Lotion USP 1%. Food and Drug Administration (FDA). [Accessed on 1st August 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/006309lotionlbl.pdf

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Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)

Last updated on 05 Aug 2024 | 04:33 PM(IST)