Rezult 8mg Tablet 10
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Introduction About REZULT 8MG TABLET
REZULT 8MG TABLET contains Rosiglitazone which belongs to the group of medicines known as Anti-diabetic agents. It is used with diet and exercise to manage type 2 diabetes mellitus (high blood sugar levels). This medicine may be used alone or with other anti-diabetic medication. It can help your body respond better to insulin made in your body.
Type 2 diabetes happens when a person does not make enough insulin or does not respond normally to the insulin their body makes. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems including kidney damage, heart disease, loss of limbs, and blindness. Diet and exercise can help your body use its blood sugar better. It is important to stay on your recommended diet, lose excess weight, and get regular exercise while taking this medicine.
REZULT 8MG TABLET is not recommended for type 1 diabetes mellitus, diabetic ketoacidosis and severe heart problems. Before taking REZULT 8MG TABLET inform your doctor if you have any liver and kidney problems. REZULT 8MG TABLET is not recommended for breastfeeding women. Consult your doctor before taking the medicine. The most common side effects of taking REZULT 8MG TABLET are cold-like symptoms, headache, weight gain and broken bones, usually in the hand, upper arm or foot. Consult your doctor if any of the above side effects worsens or persists for a longer duration.
Uses Of REZULT 8MG TABLET
- It is used with diet and exercise to manage type 2 diabetes mellitus (high blood sugar levels)
How REZULT 8MG TABLET Works
REZULT 8MG TABLET improves glycemic control by improving insulin sensitivity. It is a highly selective and potent agonist for the peroxisome proliferator-activated receptor-gamma (PPARγ). PPAR receptors are found in key target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPARγ nuclear receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization.
How to use REZULT 8MG TABLET
Take REZULT 8MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.
Side Effects Of REZULT 8MG TABLET
Common
- Cold-like symptoms
- Headache
- Weight gain
- Broken bones, usually in the hand, upper arm or foot
- Increase in total cholesterol levels
- Low red blood cell count (anemia)
Uncommon
- Constipation
- Increased hunger
Stop taking REZULT 8MG TABLET and inform your doctor immediately, if you experience the following:
- Swelling or fluid retention, especially in the ankles or legs
- Shortness of breath or trouble breathing, especially when you lie down
- An unusually fast increase in weight
- Unusual tiredness
- Chest pressure
- Low blood sugar (hypoglycemia)
- Lightheadedness, dizziness, shakiness
- Nausea or vomiting, stomach pain
- Loss of appetite
- Dark urine
- Yellowing of the skin or the whites of eyes
How To Manage Side Effects
Headache
Rest in a quiet, dark room. Apply hot or cold compresses to the head or neck.
Hypoglycemia
Eat or drink 15 to 20 grams of fast-acting carbohydrates. These are sugary foods or drinks without protein or fat that are easily converted to sugar in the body. Have a snack or meal.
Warning & Precautions
Pregnancy
Consult your doctorIt is not known if REZULT 8MG TABLET can harm unborn baby during pregnancy. If you are a premenopausal woman who does not have regular monthly periods. This medicine may increase chances of becoming pregnant. Talk to your doctor about birth control choices while taking REZULT 8MG TABLET.
Breastfeeding
ContraindicatedREZULT 8MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
Liver
Use with CautionREZULT 8MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking the medicine.
Allergy
ContraindicatedDo not take REZULT 8MG TABLET if you are allergic or hypersensitive to Rosiglitazone or any other ingredients of this medicine.
Heart Disease
ContraindicatedREZULT 8MG TABLET is not recommended for patients with severe heart failure (very poor pumping ability of the heart) and heart failure with symptoms (such as shortness of breath or swelling). Consult your doctor for advice.
Use In Pediatrics
Consult your doctorREZULT 8MG TABLET has not been studied enough in children and adolescents under 18 years of age to know if it is safe or effective in children.
Use In Geriatrics
Use with CautionREZULT 8MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor for advice before taking the medicine.
Others
REZULT 8MG TABLET is contraindicated if you have:
- Type 1 diabetes or had diabetic ketoacidosis
- A type of diabetic eye disease called macular edema (swelling of the back of the eye)
Interactions
A. Drug-Drug interactions:
Before taking REZULT 8MG TABLET, inform your doctor if you are taking any of the following medicines:
- Other medicines used for diabetes mellitus (such as insulin or metformin)
- Nitroglycerin or isosorbide (used for chest pain)
- Gemfibrozil (used to lower cholesterol and triglyceride levels in blood)
- Medicine used for infection (rifampin)
Overdosage:
If you or anyone else accidentally took more of REZULT 8MG TABLET consult your doctor immediately or visit nearby hospital.
Synopsis
| Drug | : | Rosiglitazone |
| Pharmacological Category | : | Thiazolidinediones |
| Therapeutic Indication | : | Type 2 diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep REZULT 8MG TABLET out of reach of children
- Store REZULT 8MG TABLET at room temperature
FAQs About REZULT 8MG TABLET
Q: What is REZULT 8MG TABLET used for?
A: It is used with diet and exercise to manage type 2 diabetes mellitus (high blood sugar levels). This medicine may be used alone or with other anti-diabetic medication. It can help your body respond better to insulin made in your body.
Q: How and when to take REZULT 8MG TABLET?
A: Take REZULT 8MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.
Q: Can I stop taking REZULT 8MG TABLET without consulting the doctor?
A: No. You should not stop taking REZULT 8MG TABLET without consulting the doctor because it may cause some side effects.
Q: Will taking a higher dose of REZULT 8MG TABLET be more effective?
A: No, taking a higher dose of REZULT 8MG TABLET will not be effective. Always stick to the dose and duration prescribed by your doctor.
Q: How much REZULT 8MG TABLET should I take?
A: REZULT 8MG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.
Q: Is it safe to use REZULT 8MG TABLET on elderly patients?
A: REZULT 8MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor for advice before taking the medicine.
References
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.
2. Jennifer M. Malinowski PharmD a, Scott Bolesta PharmD. Rosiglitazone in the treatment of type 2 diabetes mellitus: a critical review. Science direct. [Accessed on December 28th, 2023] https://www.sciencedirect.com/science/article/abs/pii/S014929180083060X
3. GlaxoSmithKline. 1999. [Revised on November, 2020] [Accessed on December 28th 2023] https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Avandia/pdf/AVANDIA-PI-MG.PDF
4. GlaxoSmithKline Inc. [Revised on October 04, 2017] [Accessed on December 28th 2023] https://ca.gsk.com/media/6148/avandia.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin-Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
- Jaanch Diabetic Profile Basic
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