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Introduction About REPACHEM 1 TABLET
REPACHEM 1 TABLET contains Repaglinide which belongs to the group of medicines called Antidiabetics. It is used to manage type 2 diabetes as an adjunct to diet and exercise.
Type 2 diabetes is a disease condition in which the pancreas does not make enough insulin to control sugar in the body or the body does not react well to insulin that is produced thus, leading to high blood glucose levels. The symptoms of high blood sugar level are feeling thirsty, increased urination, dry skin, and dry mouth.
Along with the management with REPACHEM 1 TABLET your doctor may advise you to make some lifestyle changes such as having a balanced diet, good sleep, exercising. Before starting the managements with REPACHEM 1 TABLET your doctor would want you to take some diagnostic tests.
REPACHEM 1 TABLET is not recommended in patients who have severe liver disease, diabetes type 1 and diabetic ketoacidosis. Consult your doctor for advice.
Patients having moderate liver diseases, kidney problems or are about to have a surgery should take REPACHEM 1 TABLET with caution.
REPACHEM 1 TABLET should not be taken by pregnant or breast-feeding women, children and adolescents below 18 years of age.
It is also not recommended for use in elderly patients above 75 years of age. The most common side-effects of REPACHEM 1 TABLET are hypoglycaemia, stomach pain and diarrhoea. Talk to your doctor if these worsen or doesn’t improve.
Uses Of REPACHEM 1 TABLET
- Used to manage type 2 diabetes mellitus
How REPACHEM 1 TABLET Works
REPACHEM 1 TABLET helps in reducing the blood sugar levels by acting on specific cells (beta cells) present in the pancreas and increases the release of insulin. Insulin is responsible for bringing the blood sugar levels down.
How to use REPACHEM 1 TABLET
Take REPACHEM 1 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of REPACHEM 1 TABLET
Common
- hypoglycaemia
- stomach pain
- diarrhoea
Rare
- acute coronary syndrome
Stop taking REPACHEM 1 TABLET if you experience any of the following side effects and talk to your doctor immediately:
- anaphylactic reaction characterised by swelling, difficulty in breathing, rapid heartbeat, feeling dizzy and sweating
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Stomach Pain
Try to rest and relax. Eat and drink slow or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedREPACHEM 1 TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedREPACHEM 1 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or use machineries after taking REPACHEM 1 TABLET if you feel a hypoglycaemic state. Consult your doctor.
Alcohol
Use with CautionAvoid the consumption of alcohol as it may change the ability of REPACHEM 1 TABLET to lower down blood sugar. Consult your doctor for advice.
Kidney
Use with CautionREPACHEM 1 TABLET should be taken with caution in patients with kidney disease. Consult your doctor before taking.
Liver
Consult your doctorREPACHEM 1 TABLET is generally not recommended in patients with severe liver disease. It should be used with caution in patients with moderate liver disease. Consult your doctor before taking the medicine.
Allergy
ContraindicatedDo not take REPACHEM 1 TABLET if you are allergic to Repaglinide or any ingredients of this medicine.
Use In Pediatrics
ContraindicatedREPACHEM 1 TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.
Use In Geriatrics
Use with CautionREPACHEM 1 TABLET should be used with caution in elderly patients above 75 years of age. Consult your doctor before taking.
Others
REPACHEM 1 TABLET is not recommended for use if you:
- have type 1 diabetes
- have diabetic ketoacidosis
Before taking REPACHEM 1 TABLET inform your doctor if you:
- have a major surgery
- have or had an infection or severe illness
Interactions
A. Drug - Drug Interactions:
- medicines used to manage depression (Ex. Monoamine oxidase inhibitors)
- medicines used to manage high blood pressure or heart conditions, beta blockers (Ex. propranolol), ACE inhibitors (Ex. captopril, enalapril)
- salicylates (Ex. aspirin)
- medicines used to manage cancer (Ex. octreotide)
- medicines used as painkiller, NSAIDS (Ex. paracetamol, naproxen)
- medicines used for anaemia or to manage inflammation (Ex. steroids)
- oral contraceptives (used as birth control pills)
- diuretics or water pills (Ex. thiazides)
- medicines used to manage breast cysts and endometriosis (Ex. danazol)
- medicines used to manage low levels of thyroid hormones (Ex. levothyroxine)
- medicines used to manage asthma, sympathomimetics (Ex. albuterol, terbutaline)
- antibiotic medicines (Ex. clarithromycin, trimethoprim, rifampicin)
- antifungal medicines (Ex. itraconazole, ketoconazole)
- medicines used to manage high blood fats (Ex. gemfibrozil)
- medicines used to suppress the immune system (Ex. ciclosporin)
- medicines used to reduce chronic iron overload (Ex. deferasirox)
- medicines used to manage epilepsy (Ex. phenytoin, carbamazepine, phenobarbital)
- St. John’s wort (herbal medicine)
- medicines used to manage blood clots (Ex. clopidogrel)
Overdosage:
If you or anyone else accidentally takes too much of REPACHEM 1 TABLET it can lead to hypoglycaemia. Inform your doctor immediately or visit the nearby hospital. Symptoms of overdosage of REPACHEM 1 TABLET are cold sweat, cool pale skin, headache, fast heartbeat, nausea, feeling very hungry, temporary changes in vision, drowsiness, unusual tiredness and weakness, nervousness or tremor, feeling anxious and confused, and difficulty in concentrating.
Synopsis
| Drug | : | Repaglinide |
| Pharmacological Category | : | Meglitinides |
| Therapeutic Indication | : | Type 2 Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
- Keep REPACHEM 1 TABLET out of reach of children
- Store at room temperature
FAQs About REPACHEM 1 TABLET
Q: Can REPACHEM 1 TABLET be used alone to manage diabetes mellitus type 2?
A: No. REPACHEM 1 TABLET is used in the management of diabetes mellitus type 2 or non-insulin dependent diabetes mellitus as an adjunct to diet or when diet and other sugar lowering medications are not working enough. Your doctor will be able to better understand your condition and manage accordingly.
Q: Is overdose of REPACHEM 1 TABLET likely to cause hypoglycaemia (abnormally low blood sugar)?
A: Yes. overdose of REPACHEM 1 TABLET may cause hypoglycaemia. Symptoms of overdosage of REPACHEM 1 TABLET are cold sweat, cool pale skin, headache, fast heartbeat, drowsiness, unusual tiredness and weakness, nausea, feeling very hungry, temporary changes in vision, nervousness or tremor, feeling anxious and confused, and difficulty in concentrating. If you or anyone else happens to have an overdose of REPACHEM 1 TABLET contact your doctor immediately.
Q: What to do if I forget to take a dose of REPACHEM 1 TABLET?
A: If you forgot to take a dose of REPACHEM 1 TABLET then do not take the missed dose between meals. Wait until your next scheduled dose and meal and continue taking your medicine as per normal. Do not take a double dose of REPACHEM 1 TABLET to make up for a forgotten dose. Consult your doctor.
Q: Can I stop taking REPACHEM 1 TABLET on my own?
A: No. You should not stop taking REPACHEM 1 TABLET without the advice of the doctor. If you do so, the desired effect may not be achieved, and your blood sugar level can happen to rise again.
Q: Can REPACHEM 1 TABLET be used in children and adolescents?
A: No. REPACHEM 1 TABLET is not recommended to use in children and adolescents (below 18 years of age). Consult your doctor.
References
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 273.
2. Zara Milner, Hossein Akhondi. Repaglinide. NIH National Library of Medicine, National center for biotechnology information. Jan 2022. [Accessed on 29th January 2024] https://www.ncbi.nlm.nih.gov/books/NBK559305/#article-93347.s3
3. Accord Healthcare. Electronic Medicines Compendium (EMC). [Revised in Jan 2019]. [Accessed on 29th January 2024] https://www.medicines.org.uk/emc/files/pil.4629.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Random Blood Sugar (RBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin – Fasting
- Insulin Postprandial (PP)
- Vital Diabetes Care
- Extended Diabetes Care
- Advance Diabetes Care
- Comprehensive Diabetes Care
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