Dr. Reddy's Laboratories Ltd

Relent Plus Syrup 60ml

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    Introduction About RELENT PLUS SYRUP

    Relent Plus Syrup 60 ml is commonly used when a wet cough is accompanied by allergy-related symptoms such as sneezing, runny nose, or throat irritation. It combines Ambroxol, a mucolytic that helps thin and loosen thick phlegm, with Cetirizine, an antihistamine that reduces allergic responses in the respiratory tract. This combination supports easier mucus clearance and improves overall breathing comfort, especially during seasonal changes or exposure to dust and allergens.

    This syrup is considered suitable for adults and children (only when advised by a healthcare professional) who experience productive cough with chest congestion and allergic cough symptoms. It may be particularly helpful for individuals whose cough worsens at night or is triggered by environmental allergens. By reducing mucus viscosity and calming airway irritation, it helps improve day-to-day respiratory comfort.

    Relent Plus Syrup should be taken exactly as directed by the doctor, usually after food to minimize stomach discomfort. The dosage and duration depend on the patient’s age, symptom severity, and medical history. While using this syrup, adequate fluid intake is recommended to support mucus thinning. Caution is advised when driving or operating machinery, as mild drowsiness or dizziness may occur due to the antihistamine component.

    Before using Relent Plus Syrup, inform your doctor if you have liver or kidney conditions, a history of drug allergies, or are taking other medicines that cause sleepiness. During pregnancy and breastfeeding, the syrup should be used only if clearly recommended by a healthcare professional, based on individual benefit–risk assessment. Common side effects may include sleepiness, dry mouth, dizziness, headache, or mild stomach upset, which are usually temporary. Seek medical advice if symptoms persist or any unusual reactions are noticed. 

    Uses Of RELENT PLUS SYRUP

    • Used to manage wet (productive) cough
    • Loosens and thins thick mucus for easier expulsion
    • Helps support airway clearance

    Benefits of RELENT PLUS SYRUP

    Relent Plus Syrup: Effectively Loosens Thick Mucus

    Relent Plus Syrup contains ambroxol, which helps thin and loosen thick mucus in the airways. By reducing the stickiness of mucus, it supports easier movement and clearance from the chest. This helps reduce the feeling of heaviness or congestion. Looser mucus is easier to expel while coughing. Regular use as advised may improve overall breathing comfort.

    Relent Plus Syrup: Helps in Productive Cough

    Relent Plus Syrup supports productive coughing by improving mucus flow in the air passages. Instead of suppressing the cough, it helps the body clear out accumulated phlegm more effectively. This can make coughing feel more useful and less exhausting. Productive coughing supports airway cleanliness. Use the syrup as directed for best results.

    How RELENT PLUS SYRUP Works

    Mechanism of Action of Relent Plus Syrup (Ambroxol + Cetirizine)

    Relent Plus Syrup combines two active ingredients Ambroxol and Cetirizine that work together to support respiratory comfort. Ambroxol helps in thinning and loosening thick mucus in the air passages, while Cetirizine helps in reducing allergic responses that may trigger cough, sneezing, or throat irritation. Together, they support smoother airflow and ease breathing discomfort associated with mucus build-up and allergy-related symptoms.

    Action of Ambroxol on Mucus

    Ambroxol acts as a mucolytic agent, meaning it helps break down thick and sticky mucus present in the respiratory tract. It works by altering the structure of mucus, making it thinner and less dense. This helps in reducing congestion and allows mucus to move more freely. By loosening phlegm, Ambroxol makes coughing more productive and supports natural clearance of secretions from the lungs and airways.

    Stimulation of Mucus Transport

    In addition to thinning mucus, Ambroxol also stimulates the activity of tiny hair-like structures called cilia present in the respiratory lining. These cilia move rhythmically to push mucus upward toward the throat, where it can be coughed out easily. This process, known as mucociliary clearance, helps keep the airways clean and supports better breathing comfort.

    Action of Cetirizine on Airways

    Cetirizine is an antihistamine that works by blocking histamine receptors in the body. Histamine is a chemical released during allergic reactions that can cause sneezing, watery eyes, runny nose, and throat irritation. By preventing histamine from attaching to its receptors, Cetirizine helps reduce allergy-related airway irritation and mucus production. This supports clearer breathing and reduces discomfort associated with allergic triggers.

    How to use RELENT PLUS SYRUP

    • Take the syrup exactly as prescribed by your doctor
    • Measure the dose using a proper measuring cup or spoon
    • Usually taken after food to reduce stomach discomfort
    • Shake the bottle well before each use
    • Take it at the same time each day for best results
    • Do not exceed the recommended dose
    • Continue use for the duration advised by your healthcare professional

    What if I forgot to take RELENT PLUS SYRUP

    • Take the missed dose as soon as you remember
    • Skip the missed dose if it is almost time for the next dose
    • Do not take a double dose to make up for the missed one
    • Continue with the regular dosing schedule
    • If you miss doses frequently, set a reminder or consult your doctor
    • Contact a healthcare professional if you are unsure what to do

    Overdose

    If someone accidentally takes more than the recommended amount of Relent Plus Syrup 60 ml, seek medical advice immediately or visit the nearest healthcare facility.

    Side Effects Of RELENT PLUS SYRUP

    Common side effects of Relent plus syrup 60ml

    • Feeling drowsy or sleepy / sedation
    • Dizziness or light-headedness
    • Dry mouth
    • Fatigue or unusual tiredness
    • Upset stomach including nausea or vomiting

    When to Seek Medical Attention?

    Stop taking Relent Plus Syrup and contact your doctor immediately if you experience any of the following side effects:

    • Severe or persistent chest pain or tightness
    • Rapid, irregular, or pounding heartbeat
    • Severe dizziness or fainting
    • Difficulty breathing or sudden worsening of breathing discomfort
    • Swelling of the face, lips, tongue, or throat
    • Skin rash, itching, or hives suggesting an allergic reaction
    • Severe tremors or uncontrollable shaking
    • Persistent vomiting or severe stomach discomfort

    How To Manage Side Effects

    Dizziness Or Drowsiness

    • Sit or Lie Down Immediately: If you feel dizzy, sit or lie down right away to avoid falls or imbalance. Rest until the feeling passes.
    • Stay Hydrated: Drink plenty of fluids such as water, coconut water, or lemon water. Dehydration is a common cause of dizziness.
    • Eat Small, Frequent Meals: Low blood sugar may trigger dizziness. Eat balanced meals with complex carbs, proteins, and fruits.
    • Avoid Sudden Movements: Stand up slowly from sitting or lying positions to prevent a drop in blood pressure that can cause light-headedness.
    • Get Fresh Air: Step outside or open a window to improve oxygen flow and reduce feelings of giddiness.
    • Reduce Caffeine and Alcohol: Both can cause dehydration or affect blood circulation, increasing dizziness episodes.
    • Deep Breathing or Relaxation: Gentle breathing exercises can calm your nervous system and improve oxygen flow.
    • Monitor Medications: Some medicines can cause dizziness as a side effect if it occurs often, consult your healthcare professional for guidance.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    Relent Plus Syrup (Ambroxol + Cetirizine) should be used during pregnancy only if clearly advised by your doctor. Safety may vary depending on the trimester and individual health condition. Avoid self-medication if you are pregnant or planning to conceive. Always consult your healthcare professional before starting this syrup.  

    Breastfeeding

    Use with Caution

    Relent Plus Syrup should be used with caution while breastfeeding. Cetirizine may pass into breast milk in small amounts. A doctor should evaluate the benefits and possible risks before use during nursing. Follow medical guidance carefully.  

    Driving and Using Machines

    Use with Caution

    Relent Plus Syrup may cause drowsiness, dizziness, or reduced alertness in some individuals due to cetirizine. Avoid driving or operating heavy machinery if you feel sleepy or less attentive. Resume such activities only when you feel fully alert and comfortable. 

    Alcohol

    Contraindicated

    Avoid consuming alcohol while taking Relent Plus Syrup. Alcohol may increase drowsiness and dizziness caused by cetirizine. This combination can affect alertness and coordination. Limiting alcohol intake supports safer use.

    Kidney

    Use with Caution

    Relent Plus Syrup should be used cautiously in individuals with kidney-related conditions. Dose adjustment may be required, especially because cetirizine is cleared through the kidneys. Inform your doctor about any kidney problems before use.  

    Liver

    Consult your doctor

    Patients with liver disorders should use Relent Plus Syrup under medical supervision. Although generally well tolerated, medical guidance helps ensure appropriate dosing. Always inform your healthcare provider about any liver conditions.    

    Allergy

    Contraindicated

    Do not use Relent Plus Syrup if you are allergic to ambroxol, cetirizine, or any of its ingredients. Stop taking the syrup if you notice rash, itching, swelling, or breathing difficulty. Seek immediate medical attention if allergic symptoms appear.

    Heart Disease

    Use with Caution

    Relent Plus Syrup should be used carefully in individuals with existing heart conditions. Although uncommon, some people may experience palpitations or mild changes in heart rate. Consult your doctor if you have a history of heart disease.  

    Use In Pediatrics

    Consult your doctor

    Relent Plus Syrup may be given to children only under medical advice. The dose should be adjusted according to age and body weight. Do not administer without consulting a doctor.    

    Use In Geriatrics

    Use with Caution

    Elderly patients should use Relent Plus Syrup cautiously, as they may be more sensitive to drowsiness or dizziness. Dose adjustment may be considered in older adults, especially with kidney concerns. Always follow the prescribed instructions.  

    Who should not take RELENT PLUS SYRUP

    Relent Plus Syrup is not recommended for use if you have:

    • Rare hereditary problems such as galactose intolerance (if the formulation contains certain sugars – check label)

    Safety Advice

    • Dose accuracy: Always use a proper measuring cup or spoon to avoid under- or over-dosing. Household spoons may give inaccurate amounts.
    • Timing consistency: Take the syrup at the same times each day to maintain consistent effect. Irregular timing may reduce perceived benefit.
    • Short-term use awareness: Relent Plus Syrup is generally intended for short-term use. If symptoms persist beyond the advised period, medical review is recommended.
    • Avoid abrupt changes: Do not stop or restart the syrup frequently without advice, as inconsistent use may affect symptom control.
    • Label check before use: Always check the bottle label for formulation details, especially if you are monitoring sugar intake or using other cough products.
    • Missed dose handling: If a dose is missed, continue with the next scheduled dose. Do not take extra syrup to compensate.
    • Symptom monitoring: Pay attention to changes in cough pattern, breathing comfort, or throat irritation, and report unusual changes to your doctor.
    • Avoid unnecessary combinations: Do not combine with herbal cough mixtures or home remedies unless advised, as this may alter effectiveness.

    Diet and Lifestyle Advice

    • Stay well hydrated: Drink plenty of water and warm fluids such as soups or herbal teas. Adequate hydration helps keep mucus thin and easier to clear.
    • Prefer light, warm meals: Choose easily digestible foods like porridge, rice, steamed vegetables, and fruits. Avoid very cold foods that may irritate the throat.
    • Limit irritants: Avoid smoking and exposure to second-hand smoke, dust, or strong fumes, as these may worsen cough and breathing discomfort.
    • Moderate caffeine intake: Excessive tea, coffee, or energy drinks may increase restlessness or palpitations in some people. Consume in moderation while using the syrup.
    • Rest adequately: Allow your body sufficient rest to support recovery. Avoid strenuous physical activity if you feel tired or short of breath.
    • Maintain upright posture: Sitting upright or keeping the head elevated while resting may help reduce cough discomfort and improve breathing ease.
    • Avoid sudden temperature changes: Protect yourself from cold air, air-conditioned environments, and sudden weather changes that may trigger coughing.
    • Follow regular meal timing: Taking the syrup after meals may help reduce stomach discomfort in some individuals.
    • Practice respiratory hygiene: Cover your mouth while coughing and wash hands regularly to reduce spread of respiratory discomfort to others.

    1. Relent Plus Syrup Vs Ambroxol Syrup – wet cough

    Feature

    Relent Plus Syrup (Ambroxol + Cetirizine)

    Ambroxol Syrup (Plain Ambroxol)

    Composition

    Ambroxol + Cetirizine

    Ambroxol only

    Type of Action

    Mucolytic + Antihistamine

    Mucolytic

    How It Works in Wet Cough

    Ambroxol helps thin and loosen mucus, while cetirizine reduces allergy-related symptoms like sneezing and runny nose

    Ambroxol helps thin, break down, and clear thick mucus from the airways

    Best Suited For

    Wet cough associated with allergy symptoms (sneezing, watery eyes, nasal irritation)

    Wet cough mainly due to mucus buildup without allergy symptoms

    Effect on Mucus

    Helps loosen mucus for easier clearance

    Helps loosen and make mucus easier to expel

    Effect on Allergy Symptoms

    Helps reduce allergy-related symptoms

    Does not act on allergy symptoms

    Drowsiness Risk

    May cause mild drowsiness due to cetirizine

    Usually, non-drowsy

    Use in Children

    Given under medical advice with age-appropriate dose

    Given under medical advice with age-appropriate dose

    Use in Daytime

    Use cautiously if drowsiness occurs

    Generally suitable for daytime use

    When Doctor May Prefer It

    When wet cough is accompanied by allergic cold symptoms

    When only mucus-related cough is present

    Drug - Drug interaction

    1. Other Antihistamines (e.g., Chlorpheniramine, Diphenhydramine)

    • Interaction: Using multiple antihistamines together may increase the risk of excessive drowsiness, dry mouth, blurred vision, and urinary retention.
    • Management: Avoid taking additional antihistamines unless prescribed. Check cough and cold combinations carefully, as many contain antihistamines. Consult your doctor before combining.

    2. Sedatives and Sleeping Pills (e.g., Diazepam, Alprazolam, Zolpidem)

    • Interaction: Cetirizine may enhance the sedative effect of sleeping pills or anti-anxiety medications, leading to increased sleepiness and reduced alertness.
    • Management: Use cautiously under medical supervision. Avoid activities requiring full alertness if taken together. Dose adjustments may be considered.

    3. Opioid Pain Relievers (e.g., Codeine, Tramadol, Morphine)

    • Interaction: Combination may increase drowsiness, dizziness, and slowed reaction time.
    • Management: Medical supervision is recommended. Avoid driving and monitor for excessive sedation. Inform your doctor if unusual sleepiness occurs.

    4. Theophylline

    • Interaction: High doses of theophylline may slightly reduce the clearance of cetirizine, potentially increasing its levels in the body.
    • Management: Usually no major dose adjustment is required, but monitoring for increased drowsiness may be advised.

    5. Ritonavir (used in HIV therapy)

    • Interaction: Ritonavir may increase cetirizine concentration in the body.
    • Management: Use with caution. Doctor may monitor for side effects such as drowsiness or fatigue.

    6. Other Mucolytics or Cough Medicines

    • Interaction: Combining multiple cough formulations may lead to unnecessary duplication of therapy.
    • Management: Avoid self-combining cough syrups. Consult your doctor to prevent overlapping ingredients.

    7. Muscle Relaxants

    • Interaction: May enhance dizziness or drowsiness when used with cetirizine.
    • Management: Use carefully and monitor for increased sedation. Avoid tasks requiring alertness.

    Drug - Food interaction

    1. Caffeinated Beverages (Tea, Coffee, Energy Drinks)

    • Interaction: Caffeine does not directly interact with ambroxol or cetirizine, but it may mask drowsiness caused by cetirizine. This can give a false sense of alertness.
    • Management: Consume caffeine in moderation. Do not rely on caffeine to counteract sleepiness caused by the medicine.

    2. Heavy or Fatty Meals

    • Interaction: Food does not significantly affect absorption of ambroxol or cetirizine, but heavy meals may delay the onset of action slightly.
    • Management: Relent Plus Syrup can be taken with or without food. If you experience stomach discomfort, taking it after a light meal may help.

    3. Grapefruit or Citrus Juices

    • Interaction: There is no strong evidence of a major interaction, but citrus juices may sometimes cause mild stomach irritation in sensitive individuals.
    • Management: If you notice stomach upset, take the syrup with water instead of citrus juices.

    4. Herbal Teas and Supplements (e.g., Valerian, Ashwagandha)

    • Interaction: Some herbal products that promote relaxation or sleep may enhance drowsiness when combined with cetirizine.
    • Management: Use caution when combining herbal calming agents with this syrup. Inform your doctor about any herbal supplements you are taking.

    Synopsis

    Drug

    Ambroxol, Cetirizine

    Pharmacological Category

    Mucolytic, Antihistamine

    Therapeutic Indication

    Productive (wet) cough with allergic symptoms

    Dosage Forms

     Syrup

    More Information

    Storage

    • Store at room temperature below 25°C
    • Keep out of reach of children

    FAQs About RELENT PLUS SYRUP

    Q: What is Relent Plus Syrup used for?

    A: Relent Plus Syrup is an oral medication commonly used for cough associated with mucus. It contains ambroxol and cetrizine, which help loosen mucus and support easier breathing. The syrup works by thinning secretions and relaxing airway muscles. It is usually advised as part of respiratory care. Always take it as recommended by a healthcare professional.

    Q: How should I take Relent Plus Syrup?

    A: Take Relent Plus Syrup exactly as prescribed by your doctor. Use the measuring cup or spoon provided to ensure the correct dose. It can be taken with or without food unless advised otherwise. Do not exceed the recommended quantity. Shake the bottle well before use.

    Q: Can Relent Plus Syrup be taken daily?

    A: Relent Plus Syrup may be taken daily if advised by a doctor. The dose and duration depend on age and symptom severity. Taking more than prescribed does not provide extra benefit. Follow medical guidance carefully. Consult your doctor for long-term use.

    Q: Is Relent Plus Syrup suitable for children?

    A: Relent Plus Syrup may be given to children only under medical supervision. The dose is usually adjusted based on the child’s age and weight. Do not self-medicate in young children. Use an accurate measuring device. Always follow paediatric advice.

    Q: Can Relent Plus Syrup cause drowsiness?

    A: Relent Plus Syrup usually does not cause drowsiness. However, some people may feel mild dizziness or restlessness. These effects are generally temporary. Avoid driving if you feel uncomfortable. Inform your doctor if symptoms persist.

    Q: What should I do if I miss a dose of Relent Plus Syrup?

    A: If you miss a dose, take it as soon as you remember. If it is close to the next scheduled dose, skip the missed one. Do not double the dose to compensate. Maintain a regular dosing schedule. Ask your doctor if unsure.

    Q: What happens if I take too much Relent Plus Syrup?

    A: Taking more than the recommended dose may increase the risk of side effects such as tremors or fast heartbeat. Seek medical advice if an overdose is suspected. Do not continue extra doses. Always stick to the prescribed amount.

    Q: Can Relent Plus Syrup be taken with other medicines?

    A: Relent Plus Syrup may interact with certain medicines. Inform your doctor about all ongoing medications, including inhalers and heart medicines. Do not combine with other cough syrups unless advised. Follow professional guidance carefully.

    Q: Does Relent Plus Syrup affect daily activities?

    A: Relent Plus Syrup generally does not interfere with daily routines. Most people can continue normal activities. If you experience dizziness or palpitations, rest and avoid exertion. Consult your doctor if discomfort occurs.

    Q: How long should Relent Plus Syrup be used?

    A: The duration of use depends on individual condition and response. Some people may need short-term use only. Prolonged use should be monitored by a doctor. Do not continue beyond the advised period. Follow medical instructions closely.

    Q: Can Relent Plus Syrup be taken with food?

    A: Relent Plus Syrup can usually be taken with or without food. Taking it after meals may help reduce stomach discomfort. Follow your doctor’s advice if you have digestion issues. Maintain consistent timing for best results.

    Q: What are common side effects of Relent Plus Syrup?

    A: Some people may experience mild nausea, headache, tremors, or throat irritation. These effects are usually temporary. Serious side effects are uncommon. Inform your doctor if symptoms worsen or persist.

    Q: Can Relent Plus Syrup be used in elderly patients?

    A: Elderly patients may use Relent Plus Syrup under medical guidance. Dose adjustments may be needed in some cases. Monitor for side effects like palpitations. Regular follow-up is recommended.

    Q: Does Relent Plus Syrup contain sugar?

    A: Some formulations may contain sugar. People with diabetes should check the label or consult a doctor before use. Sugar-free alternatives may be available. Always follow medical advice.

    Q: Can Relent Plus Syrup be shared with others?

    A: Relent Plus Syrup should not be shared with others. Dosage varies based on individual needs. Sharing may lead to incorrect use. Always use medicines prescribed specifically for you.

    Q: When should I consult a doctor while using Relent Plus Syrup?

    A: Consult a doctor if symptoms do not improve or worsen. Seek medical advice if side effects occur. Prolonged use requires supervision. Always follow professional recommendations.

    References

    1.K.D. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Seventh Edition. 2013.

    2. Amit Garg, Bharath Venkata Ramisetty, Nirmal Choraria, Kirti Sisodiya, Monidipa Banerjee, Shyam Akku. Therapeutic Benefit of Addition of Cetirizine to Ambroxol in Fixed Dose Combination in the Treatment of Productive Cough in Children: A Prospective, Multi-center Study. American Journal of Internal Medicine. Science Publishing Group. [Revised in 28th November 2017] [Accessed on 12th February 2026]

    3. Advacare Pharma. Ambroxol HCl + Cetirizine HCl Syrup. [Revised in 14th October 2024] [Accessed on 12th February 2026]

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)
    Last updated on 26 Feb 2024 | 11:56 AM(IST)
    Lab updated