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Introduction About REJUNEX OD CAPSULE
REJUNEX OD CAPSULE is a combination of Alpha lipoic acid, Methylcobalamin, Folic acid, and Pyridoxine, which belong to the group of medicines called Antioxidants and Vitamin B complexes, respectively. It is used to manage diabetic neuropathy (nerve damage occurring over time because of high sugar and fat levels in the blood due to diabetes).
Symptoms depend on the type of neuropathy, such as pain and numbness in your feet or problems with organ functions like those of your heart and bladder. It can also be used to manage general weakness and convalescence (recovering from an illness or injury).
REJUNEX OD CAPSULE is not recommended for use in children, so consult your doctor before taking it. Before taking REJUNEX OD CAPSULE, inform your doctor if you have any liver or kidney problems, cancer, a tumour, pernicious anaemia, are undergoing dialysis, or if you have a coronary stent.
REJUNEX OD CAPSULE should not be used in pregnant women unless necessary. REJUNEX OD CAPSULE is not recommended for use by breastfeeding women. The most common side effects of REJUNEX OD CAPSULE are headache, low blood pressure, shortness of breath, a hot sensation, or sweating. Contact your doctor if any of the symptoms get worse.
Uses Of REJUNEX OD CAPSULE
- Manage diabetic neuropathy
- Manage general weakness
- Manage convalescence
How REJUNEX OD CAPSULE Works
REJUNEX OD CAPSULE helps relieve nerve pain where methylcobalamin takes part in the production of myelin, a compound that covers and protects nerve fibers, thus restoring the damaged nerve cell, and alpha-lipoic acid reduces oxidative stress, which is considered the main pathophysiology of diabetic neuropathy development. Folic acid (Vitamin B9) improves the functional recovery of nerves, the speed of nerve conduction, and cell multiplication, while pyridoxine acts as a coenzyme in a wide range of metabolic functions affecting protein, carbohydrate, and lipid utilization, like the breakdown of glycogen to glucose-1-phosphate and the synthesis of gamma-aminobutyric acid (GABA).
How to use REJUNEX OD CAPSULE
Take REJUNEX OD CAPSULE as advised by your physician. Swallow it with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition.
Side Effects Of REJUNEX OD CAPSULE
Common
- Headache
- A decrease in blood pressure
- Hot sensation
- Sweating
Rare
- Loss of appetite, nausea, vomiting, diarrhea
- Abdominal swelling, gas
- Allergic reactions (redness, rash, itching, hives, breathlessness, and anaphylactic reactions, including shock)
Stop taking REJUNEX OD CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- Allergic reaction (rash, itching, breathlessness, swelling of the face, lips, tongue, or throat)
- A decrease in blood sugar levels
How To Manage Side Effects
Headache
Drink an ample amount of water and get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine for a headache. If the headache does not improve, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedREJUNEX OD CAPSULE is not recommended for use by pregnant women unless considered necessary. Consult your doctor before taking it.
Breastfeeding
ContraindicatedREJUNEX OD CAPSULE is not recommended for use by breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel sleepy or dizzy after taking REJUNEX OD CAPSULE.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking REJUNEX OD CAPSULE because it may cause serious problems if you are thiamine deficient.
Kidney
Use with CautionREJUNEX OD CAPSULE should be taken with caution in patients with kidney problems or those undergoing haemodialysis due to kidney failure. Consult your doctor before taking it.
Liver
Use with CautionREJUNEX OD CAPSULE should be taken with caution in patients with liver problems. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take REJUNEX OD CAPSULE if you are allergic to alpha-lipoic acid, methylcobalamin, folic acid, pyridoxine, or any of the other ingredients of this medicine.
Heart Disease
Use with CautionREJUNEX OD CAPSULE should be taken with caution in patients who have received a coronary stent (a tube inserted in the artery that leads to the heart) to manage blockages. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedREJUNEX OD CAPSULE is not recommended for use with children. Consult your doctor before taking it.
Use In Geriatrics
Consult your doctorYour doctor will prescribe the right dose of REJUNEX OD CAPSULE depending on your age, body weight, and health condition. Consult your doctor before taking it.
Others
REJUNEX OD CAPSULE is not recommended for use if you:
- Have Leber’s disease (a genetic disease causing sudden vision loss)
Before taking REJUNEX OD CAPSULE, inform your doctor if you:
- Have an underactive or overactive thyroid
- Have diabetes (high blood sugar)
- Have polycythaemia vera (high numbers of red blood cells)
- Have megaloblastic anemia (abnormal red blood cells)
- Have pernicious anemia (prevention of vitamin B12 absorption) or could be having a vitamin B12 deficiency
- Have cancer (unless you have anemia due to folic acid deficiency)
- Have a tumour
Interactions
A. Drug-Drug interactions:
Before taking REJUNEX OD CAPSULE, inform your doctor if you are taking any of the following medicines:
- Medicines used to manage bacterial infections (Ex. neomycin, aminosalicylic acid, trimethoprim, sulphonamides, cotrimoxazole, and chloramphenicol)
- Medicines used to manage stomach ulcers (Ex. famotidine, omeprazole)
- Colchicine (used to manage gout)
- Medicines used to manage pregnancy (Ex. ethinylestradiol, norethindrone)
- Medicines used to manage diabetes (Ex. insulin, metformin, and glimepiride)
- Medicines used to control epileptic fits (Ex. phenytoin, fosphenytoin, phenobarbital, primidone)
- Medicines used to manage certain tumours (Ex. fluorouracil, methotrexate)
- Medicines used to manage indigestion (Ex. edible clay, aluminium, magnesium)
- Zinc (a supplement important in pregnancy)
- Sulfasalazine (used to manage inflammatory bowel diseases like ulcerative colitis and Crohn’s disease)
- Cholestyramine (used to reduce blood cholesterol)
- Levodopa (used to manage Parkinson’s disease)
- Isoniazid (used to manage tuberculosis)
- Penicillamine (used to manage arthritis)
- Pyrimethamine (used to manage parasitic infections)
- Amiodarone (used to manage an irregular heartbeat)
Overdosage:
If you or anyone else accidentally took too much of REJUNEX OD CAPSULE, contact your doctor immediately.
Synopsis
| Drug | : | Alpha Lipoic Acid, Methylcobalamin, Folic Acid, and Pyridoxine |
| Pharmacological Category | : | Antioxidants, Vitamins |
| Therapeutic Indication | : | Diabetic neuropathy, General weakness, and Convalescence |
| Dosage Forms | : | Tablet, Capsule, Soft gel Capsule |
More Information
Storage
- Keep REJUNEX OD CAPSULE out of reach from children
- Store below 25°C
FAQs About REJUNEX OD CAPSULE
Q: What is REJUNEX OD CAPSULE used for?
A: REJUNEX OD CAPSULE is used to manage diabetic neuropathy (nerve damage occurring over time because of high sugar and fat levels in the blood due to diabetes). It can also be used to manage general weakness and convalescence (recovering from an illness or injury). Consult your doctor before taking it.
Q: Can REJUNEX OD CAPSULE cause sunburn?
A: Taking REJUNEX OD CAPSULE along with amiodarone (a medicine used to manage irregular heartbeat) might increase the chances of sunburn, blistering, or rashes on the skin exposed to sunlight. Wear sunblock, a screen, and protective clothing when you are out in the sun, without fail.
Q: Can REJUNEX OD CAPSULE be given to children?
A: No, REJUNEX OD CAPSULE is intended for adults and should not be used by children. Your doctor will select a suitable alternative management plan for your child.
Q: Can I take REJUNEX OD CAPSULE if I have received a coronary stent?
A: No. Avoid using REJUNEX OD CAPSULE after receiving a coronary stent (a tube inserted in the artery that leads to the heart to manage blockages), as it may increase the risk of blood vessel narrowing. Consult your doctor for further doubts.
Q: What if I forget to take a dose of REJUNEX OD CAPSULE?
A: If you forget to take a dose of REJUNEX OD CAPSULE, take it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not take the medicine twice to make up for the forgotten dose.
Q: Can I take REJUNEX OD CAPSULE if I have any eye problems?
A: Do not take REJUNEX OD CAPSULE if you have Leber’s disease (a genetic disease causing sudden vision loss), as it can seriously harm the optic nerve, which might cause blindness. Consult your doctor before taking this medicine if you have any other eye problems.
Q: Can REJUNEX OD CAPSULE be stopped?
A: Continue taking REJUNEX OD CAPSULE until your doctor tells you to stop, unless you experience any unwanted effects, a worsening of your condition, or any new symptoms. Contact your doctor in such a case.
Q: Can I consume alcohol during management with REJUNEX OD CAPSULE?
A: Avoid consuming alcohol with REJUNEX OD CAPSULE management, as it can lower the amount of thiamine (vitamin B1) in the body. Taking this medicine when there is a thiamine deficiency might cause serious health problems. Consult your doctor for further doubts.
Q: How should REJUNEX OD CAPSULE be taken? Can it be crushed?
A: No. Do not break, crush, or chew REJUNEX OD CAPSULE. Take it as advised by your physician. Swallow it with a glass of water. Your doctor will determine the correct dose and duration for you based on your age, body weight, and disease condition.
Q: Is REJUNEX OD CAPSULE safe during pregnancy?
A: REJUNEX OD CAPSULE is not recommended for use by pregnant women unless considered necessary. Consult your doctor before taking it.
Q: What are the side effects of taking REJUNEX OD CAPSULE?
A: The most common side effects of REJUNEX OD CAPSULE are headache, low blood pressure, shortness of breath, a hot sensation, or sweating. Contact your doctor if any of the symptoms get worse.
References
1. KD Tripathi. Drugs Affecting Blood and Blood Formation. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 608.
2. Kang WB, Chen YJ, Lu DY, and Yan JZ. Folic acid contributes to peripheral nerve injury repair by promoting Schwann cell proliferation, migration, and the secretion of nerve growth factor. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. January 2019. [Accessed on 8th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263007/
3. Serhiyenko V., Serhiyenko L., Suslik G., et al., Alpha-lipoic acid: mechanisms of action and beneficial effects in the prevention and treatment of diabetic complications. MOJ Public Health. MedCrave. July 2018. [Accessed on 8th July 2024] https://medcraveonline.com/MOJPH/alpha-lipoic-acid-mechanisms-of-action-and-beneficial-effects-in-the-prevention-and-treatment-of-diabetic-complications.html
4. Duta Wacana Christian University. The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient. NIH, U.S. National Library of Medicine ClinicalTrials.gov. [Revised in December 2020] [Accessed on 8th July 2024] https://clinicaltrials.gov/ct2/show/NCT04689971?term=folic+acid&cond=Diabetic+Neuropathies&draw=2&rank=2
5. Ordain Health Care Global Pvt. Ltd. Alpha-lipoic acid, methylcobalamin, folic acid, and pyridoxine. [Revised in July 2019] [Accessed on 8th July 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2845.pdf
6. Micro Labs Ltd. Alpha Lipoic Acid, Methylcobalamin, Folic Acid, and Pyridoxine. [Accessed on 8th July 2024] https://www.microlabsltd.com/elibrary/node/1799
Useful Diagnostic Tests
- Nerve conduction testing
- Electromyography
- Complete Blood Count (CBC)/ Hemogram
- Advanced Vitamins Profile
- Vitamin Basic Package
- Complete Vitamins Profile
- Healthy Midlife Checkup
- Men Health Checkup - Advanced
- Complete Women Checkup
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