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Introduction About REGESTRONE CR 10MG TABLET
REGESTRONE CR 10MG TABLET contains Norethisterone which belongs to a group of medicines called Progestogens. It is used to manage female reproductive health.
REGESTRONE CR 10MG TABLET is not recommended for use in patients with pulmonary embolism (blood clots in the lung), liver disease, heart attack (myocardial infarction), or angina and deep vein thrombosis. REGESTRONE CR 10MG TABLET should be used with caution in patients with asthma, kidney disease, fits, and migraine headaches.
REGESTRONE CR 10MG TABLET is not recommended for use during pregnancy as it may affect the developing baby. Inform your doctor if you have had repeated miscarriages. REGESTRONE CR 10MG TABLET should be used with caution in breastfeeding women as it may pass through the breast milk. If you experience mood changes and depressive symptoms, contact your doctor as soon as possible.
The most common side effects of taking REGESTRONE CR 10MG TABLET are irregular bleeding, heavy menstruation, spotting between menstrual cycles, delayed or not having a menstrual cycle, stomach discomfort, nausea, vomiting, breast tenderness, headache, and dizziness. Contact your physician if the symptoms worsen.
Uses Of REGESTRONE CR 10MG TABLET
- To manage female reproductive health
How REGESTRONE CR 10MG TABLET Works
REGESTRONE CR 10MG TABLET inhibits the release of pituitary hormones that are responsible for the release of female hormones (such as oestrogen and progesterone) and thereby suppresses ovulation. This action modifies the lining of the endometrium and thus ceases bleeding in menstrual abnormalities in cancer. REGESTRONE CR 10MG TABLET may act by pituitary inhibition or by direct action on tumour deposits.
How to use REGESTRONE CR 10MG TABLET
Follow the instructions given by your doctor. Take REGESTRONE CR 10MG TABLET as advised according to your symptoms and disease severity. Swallow the whole tablet with a glass of water.
Side Effects Of REGESTRONE CR 10MG TABLET
Common
- irregular bleeding, heavy menstruation
- spotting between menstrual cycles
- delayed or not having a menstrual cycle
- stomach discomfort, nausea, vomiting
- breast tenderness
- headache and dizziness
Rare
Stop taking REGESTRONE CR 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- yellowing of the skin or white area of the eyes (jaundice)
- migraine headache for the very first time (a headache that usually restricts itself to one side of your head)
- high blood pressure
- symptoms of severe allergic reaction such as itchy skin rash, swelling of the face or tongue, hands or feet causing wheezing, difficulty breathing or feeling faint
- symptoms of a blood clot in the lungs include a sudden, severe, sharp pain in the chest, coughing up blood, shortness of breath, rapid heartbeats
- symptoms of a blood clot in the brain (stroke) include unusually severe or long headache, change in sight, difficulty speaking, collapsing, or fainting and weakness or paralysis of any part of your body
- symptoms of a deep-vein thrombosis such as severe pain, tenderness or swelling in your calf, ankle or foot, purplish discolouration of the skin of the leg and red or warmth skin
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel dizzy. Avoid alcohol consumption as it aggravates dizziness. Contact your doctor if the dizziness worsens.
Headache
Rest and relax. Apply a pain-relieving balm to your forehead if needed. Do not consume alcohol. Contact your doctor if your headache does not improve.
Nausea And Vomiting
Take the medicine with or just after a meal. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting get worse.
Stomach Pain
Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. Contact your doctor if the stomach pain does not improve.
Warning & Precautions
Pregnancy
ContraindicatedREGESTRONE CR 10MG TABLET is not recommended for use during pregnancy and if you have a history of Idiopathic jaundice during pregnancy or an itchy rash or blisters on the abdomen known as pemphigoid gestationis (rare autoimmune skin disorder in pregnancy) and REGESTRONE CR 10MG TABLET should be used with caution in patients with a history of repeated miscarriages. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Breastfeeding
Use with CautionREGESTRONE CR 10MG TABLET should be used with caution in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Driving and Using Machines
SafeREGESTRONE CR 10MG TABLET does not affect the ability to drive or operate machinery.
Kidney
Use with CautionREGESTRONE CR 10MG TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Liver
Use with CautionREGESTRONE CR 10MG TABLET should be used with caution in patients with liver disease. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Allergy
ContraindicatedDo not use REGESTRONE CR 10MG TABLET if you are allergic to norethisterone, similar other hormone medicines or any other ingredients in the medicine.
Lungs
Consult your doctorREGESTRONE CR 10MG TABLET is not recommended for use in patients who have or had a pulmonary embolism (blood clots in the lung) and should be used with caution in patients with asthma. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Heart Disease
ContraindicatedREGESTRONE CR 10MG TABLET is not recommended for use in patients with active or recent angina (chest pain) or heart attack. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Others
REGESTRONE CR 10MG TABLET is not recommended for use if you have:
- blood disorders like porphyria
- clotting disorders like deep vein thrombosis or a family history of the same
- pruritis (a condition with severe generalised itching of the body)
- undiagnosed vaginal bleeding (not a period)
Before taking REGESTRONE CR 10MG TABLET tell your doctor if you have:
- epilepsy
- migraine headache
- are very overweight
- systemic lupus erythematosus.
- a blood clot in the veins
- are unable to move for long periods (Ex. after an operation)
- serious injury
- have major surgery or are going to have an operation (particularly abdominal or orthopaedic surgery to the lower limbs)
- blood tests (for liver function, thyroid function, and coagulation).
- vision impairment, bulging eyes, double vision
- depression
Interactions
A. Drug-Drug Interactions:
- Antiepileptic medicines (used to manage fits) (phenytoin, carbamazepine, and phenobarbitone)
- Antibiotics Ex. tetracyclines, co-trimoxazole, ampicillin, and oxacillin (medicines used for bacterial infections)
- Medicines used for tuberculosis (rifampicin, rifabutin)
- Antiviral medicines for the management of HIV (ritonavir, nelfinavir, efavirenz)
- Anticancer medicines
- Aminoglutethimide (used in Cushing’s syndrome)
- Ciclosporin (immunosuppressants or medicines used to manage rejection of a transplanted organ)
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (medicines used for pain)
- Medicines for managing high blood pressure (amlodipine, captopril, atenolol, and telmisartan)
- St. John’s Wort (medicines used to manage depression)
Overdosage:
If you or anyone else accidentally took more of the REGESTRONE CR 10MG TABLET, contact your doctor immediately or visit a nearby hospital immediately if the symptoms worsen. The symptoms may include nausea, vomiting, breast enlargement, and vaginal bleeding.
Synopsis
| Drug | : | Norethisterone |
| Pharmacological Category | : | Progestogens |
| Therapeutic Indication | : | To manage female reproductive health |
| Dosage Forms | : | Tablet |
More Information
- Keep REGESTRONE CR 10MG TABLET below 25°C
- Keep REGESTRONE CR 10MG TABLET out of sight and reach from children
FAQs About REGESTRONE CR 10MG TABLET
Q: Can REGESTRONE CR 10MG TABLET affect the regular menstrual cycle?
A: REGESTRONE CR 10MG TABLET is a synthetic form of the hormone progesterone. Rather than allowing for the natural fall in progesterone during your period, REGESTRONE CR 10MG TABLET keeps your progesterone levels high. This delays the shedding of your womb lining and the period.
Q: When will my menstrual cycle start after taking REGESTRONE CR 10MG TABLET?
A: Your doctor will advise you when to take REGESTRONE CR 10MG TABLET and for how long. You'll usually be prescribed 3 REGESTRONE CR 10MG TABLET tablets a day, starting 3 to 4 days before you expect your period to begin. Your period should arrive 2 to 3 days after you stop taking the REGESTRONE CR 10MG TABLET.
Q: How long will REGESTRONE CR 10MG TABLET take to stop bleeding?
A: If a period is very heavy or prolonged, your doctor may advise you to take REGESTRONE CR 10MG TABLET. Bleeding will usually stop within 24–48 hours of starting management. If you wish to buy REGESTRONE CR 10MG TABLET on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.
Q: What happens if I take REGESTRONE CR 10MG TABLET too late?
A: It is important to take REGESTRONE CR 10MG TABLET three days before your menstrual cycle. If you take REGESTRONE CR 10MG TABLET too late, it may not stop your menstrual cycle from starting.
Q: Can REGESTRONE CR 10MG TABLET cause mood depression?
A: Yes, REGESTRONE CR 10MG TABLET may cause depressed mood, acne, breast tenderness, fluid retention, and loss of libido. Contact your doctor if you get any of the side effects.
Q: Can REGESTRONE CR 10MG TABLET be used as a contraceptive?
A: No, REGESTRONE CR 10MG TABLET is not indicated or effective as a contraceptive. It is primarily used for hormone replacement therapy and the management of gynaecological conditions. If you are looking for contraception, discuss suitable options with your healthcare provider.
Q: When should I take REGESTRONE CR 10MG TABLET?
A: The dosage and timing of REGESTRONE CR 10MG TABLET will depend on the specific condition being managed and your doctor's instructions. Typically, it is taken orally once daily for a prescribed duration, usually before starting your menstrual cycle.
Q: What should I do if I miss a dose of REGESTRONE CR 10MG TABLET?
A: If you miss a dose, take it as soon as you remember, but do not take a double dose to make up for the missed one. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Q: What is the use of REGESTRONE CR 10MG TABLET?
A: REGESTRONE CR 10MG TABLET is used in the management of female reproductive health. Consult your doctor before taking it.
Q: How does REGESTRONE CR 10MG TABLET work?
A: REGESTRONE CR 10MG TABLET inhibits the release of pituitary hormones that are responsible for the release of female hormones (such as oestrogen and progesterone) and thereby suppresses ovulation. This action modifies the lining of the endometrium and thus ceases bleeding in menstrual abnormalities. In cancer, REGESTRONE CR 10MG TABLET may act by pituitary inhibition or by direct action on tumour deposits.
Q: Is REGESTRONE CR 10MG TABLET safe during pregnancy?
A: REGESTRONE CR 10MG TABLET is not recommended for use during pregnancy, and if you have a history of idiopathic jaundice during pregnancy or an itchy rash or blisters on the abdomen known as pemphigoid gestation (a rare autoimmune skin disorder in pregnancy), REGESTRONE CR 10MG TABLET should be used with caution in patients with a history of repeated miscarriages. Contact your doctor before taking REGESTRONE CR 10MG TABLET.
Q: What precautions must be taken while using REGESTRONE CR 10MG TABLET?
A: Before taking REGESTRONE CR 10MG TABLET inform your doctor if you have liver disease, kidney disease, asthma, epilepsy, migraine headache, obesity, systemic lupus erythematosus, a blood clot in the veins, are unable to move for long periods (Ex. after an operation), serious injury, have major surgery or are going to have an operation (particularly abdominal or orthopaedic surgery to the lower limbs), blood tests (for liver function, thyroid function, and coagulation), vision impairment, bulging eyes, double vision, and depression.
Q: Who should not use REGESTRONE CR 10MG TABLET?
A: Do not use REGESTRONE CR 10MG TABLET if you are allergic to norethisterone, similar other hormone medicines, or have pulmonary embolism (blood clots in the lung), active or recent angina (chest pain), or a heart attack, blood disorders like porphyria, clotting disorders like deep vein thrombosis or a family history of the same, pruritis (a condition with severe generalized itching of the body), or undiagnosed vaginal bleeding (not a period).
References
1. K D Tripathi. Hormones and Related Drugs. Essentials of Medical Pharmacology. 7th Edition. Page 309-310.
2. Wockhardt UK Ltd. Electronic Medicines Compendium (EMC). [Revised in February 2020] [Accessed on 23rd March 2024] https://www.medicines.org.uk/emc/product/1494/pil
3. Norethisterone. Torrent Pharmaceuticals Ltd. [Revised in May 2020] [Accessed on 23rd March 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2955.pdf
4. Norethisterone. Torrent Pharmaceuticals Ltd. [Revised in July 2020] [Accessed on 23rd March 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2950.pdf
5. Norethisterone. Leeford Health Care Ltd. Accessed on 23rd March 2024] https://www.leeford.in/product/1516/rethrowel-10-cr
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Thyroid Stimulating Hormone (TSH)
- Free Thyroxine (Ft4)
- Free Triiodothyronine (Ft3)
- Total Thyroxine(T4)
- Total Triiodothyronine (T3)
- Healthy Midlife Checkup
- Complete Women Checkup
- Senior Citizen Checkup – Female
- Women Health Checkup - Essential
- Full Body Checkup - Gold
- Elderly Checkup – Female
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