Reclide 80mg Tablet 15'S

Introduction About RECLIDE 80MG TABLET

What is RECLIDE 80MG TABLET commonly used for?

RECLIDE 80MG TABLET is a modified-release formulation containing Gliclazide widely used to support glucose regulation in adults. It belongs to the Sulfonylurea class and is often recommended as part of a comprehensive dietary and lifestyle routine for blood sugar management.

Take RECLIDE 80MG TABLET once daily, ideally with breakfast or the first main meal of the day.

Before taking RECLIDE 80MG TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any hormonal problems, genetic disorders (such as G6PD deficiency), or if you are malnourished, starved, or on an irregular diet.

RECLIDE 80MG TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking RECLIDE 80MG TABLET if you are pregnant, planning to become pregnant, or breastfeeding women.

The most common side effects of takingRECLIDE 80MG TABLET is hypoglycemia (low blood sugar levels), which can be identified through symptoms such as increased hunger, sweating, shakiness, weakness, or an irregular heartbeat.

Uses Of RECLIDE 80MG TABLET

Used in the management of type II diabetes mellitus in adults

Benefits of RECLIDE 80MG TABLET

RECLIDE 80MG TABLET is typically used as part of a broader approach to maintaining healthy glucose levels, especially when combined with a balanced diet and physical activity.

1. Supports Stable Glucose Control

• The extended-release formula helps maintain consistent blood sugar levels throughout the day
• It minimizes sharp spikes or drops that may occur after meals

2. Once-Daily Convenience

• The slow-release design allows for once-daily dosing, making it easier to stay on track

3. Targets Natural Insulin Secretion

• Supports the body’s ability to release insulin in response to meals, helping reduce mealtime sugar surges

4. Smooth Release Mechanism

• The modified-release technology delivers Gliclazide steadily, reducing the need for multiple doses and potential side effects associated with quick drug spikes.

5. May Complement Lifestyle Modifications

• It works well alongside dietary plans and exercise routines in supporting long-term wellness goals

How RECLIDE 80MG TABLET Works

RECLIDE 80MG TABLET (Gliclazide ER) works by interacting with cells in the pancreas, specifically the beta cells responsible for releasing insulin.

1. Role of RECLIDE 80MG TABLET in Stimulating Insulin Secretion

• Gliclazide promotes the release of insulin only when blood sugar levels are high, helping regulate glucose more precisely

2. Acts on Sulfonylurea Receptors

• It binds to sulfonylurea receptors on pancreatic beta cells, triggering insulin secretion in a glucose-dependent manner

3. Promotes Glucose Utilization

• Insulin helps your body cells absorb glucose more effectively, reducing the amount circulating in the blood

Why Modified-Release Formulation Matters in Glucose Support

The slow-release system ensures that Gliclazide is absorbed gradually, providing longer-lasting support for blood sugar levels. It helps avoid the peaks and troughs that can happen with immediate-release versions, supporting a more predictable response. Gradual absorption may also mean lower risk of sudden blood sugar drops, which can sometimes occur with short-acting agents.

How Gliclazide Supports Pancreatic Function

• Gliclazide selectively targets beta cells in the pancreas to stimulate insulin release, but only when blood sugar levels are elevated. Helps ensure that insulin is released in response to meals, contributing to smoother glucose handling and reducing sugar surges.
• By working with the pancreas, rather than bypassing it, gliclazide supports the body’s own capacity to maintain sugar balance.

How to use RECLIDE 80MG TABLET

When and How to Take RECLIDE 80MG TABLET

• Take the tablet once daily, ideally with breakfast or the first main meal of the day.

Recommended Dosage for Adults and Elderly

• The usual starting dose is 30 mg to 60 mg once daily, with adjustments based on individual response.
• Elderly individuals or those with kidney or liver concerns may start at the lower end of the dosage range.
• Your healthcare provider will determine the appropriate dose after assessing lifestyle, meal patterns, and medical history.

Should RECLIDE 80MG TABLET Be Taken With Food?

• Yes, take RECLIDE 80MG TABLET with breakfast or the first substantial meal of the day.
• Taking the tablet with food helps support more natural insulin activity and reduces the risk of blood sugar fluctuations.

Can You Split or Crush RECLIDE 80MG TABLET?

• Do not split, crush, or chew the tablet. The extended-release layer is designed to release the medication slowly.
• Altering the form can lead to a sudden release of the active ingredient, potentially causing side effects or loss of efficacy.

Can RECLIDE 80MG TABLET Be Taken Once Daily?

Yes, RECLIDE 80MG TABLET is designed for once-daily use, thanks to its extended-release formulation. This slow-release mechanism maintains steady levels of the active ingredient throughout the day, supporting more consistent glucose control.

How Long Should I Take RECLIDE 80MG TABLET?

The duration for which you may be advised to take RECLIDE 80MG TABLET depends on your individual health status, lifestyle, and blood glucose monitoring results. It is generally used as part of a long-term approach to managing sugar levels alongside diet and physical activity. Your doctor will regularly assess whether continuation or adjustment is needed.

What if I forgot to take RECLIDE 80MG TABLET

• If you forget a dose, take it as soon as you remember, preferably with a meal.
• If it is nearly time for the next dose, skip the missed dose and continue as scheduled.
• Do not double the dose to make up for the missed one.

Overdose

If you or anyone else accidentally took more of RECLIDE 80MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose might include signs of low blood glucose levels such as weakness, sweating, trembling, a fast heartbeat, confusion, and double vision.

Side Effects Of RECLIDE 80MG TABLET

Common side effects of RECLIDE 80MG TABLET:

• hypoglycemia (low blood sugar levels)
• dizziness
• stomach pain
• indigestion
• diarrhea
• constipation 

When to consult the doctor?

• severe allergic reaction (such as skin rash, swelling of the face, eyelids, lips, tongue, or throat that causes difficulty breathing or swallowing)
• signs of liver problems (such as fever, yellowing of the skin and whites of the eyes, weakness, fatigue, weight loss, and loss of appetite)
• signs of a severe decrease in blood sugar level (such as confusion, headache, excessive sweating, clammy skin, trembling, weakness, double vision, excessive hunger, nausea, vomiting, problems sleeping, feeling agitated, unable to concentrate, drowsiness, loss of consciousness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, hallucinations, difficulty breathing, slowed or faster heartbeat with chest pain)

Warning & Precautions

Pregnancy

Contraindicated

RECLIDE 80MG TABLET is not recommended for use by pregnant women. Since  the European Medicines Agency (EMA) and other regulatory bodies do not recommend the use of Gliclazide during pregnancy due to lack of sufficient human studies confirming its safety.

Breastfeeding

Contraindicated

There is insufficient evidence from human studies to determine if Gliclazide passes into breast milk in significant amounts. Hence RECLIDE 80MG TABLET is not recommended for use by breastfeeding women.

Driving and Using Machines

Use with Caution

Be cautious while driving or operating machines until you know how the tablet affects you. In case of low blood sugar symptoms, avoid such activities for your safety.

Alcohol

Consult your doctor

Avoid alcohol consumption while taking RECLIDE 80MG TABLET, as it could aggravate your existing condition.

Kidney

Consult your doctor

RECLIDE 80MG TABLET is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with decreased kidney function. Regular blood sugar monitoring is important to avoid unexpected highs or lows. Periodic kidney function (eGFR, creatinine) may be advised to track organ health during ongoing use.

Liver

Consult your doctor

RECLIDE 80MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with decreased liver function. Regular blood sugar monitoring  and liver enzyme tests (ALT, AST) may be advised to track organ health during ongoing use.

Allergy

Contraindicated

Do not take RECLIDE 80MG TABLET if you are allergic to Gliclazide or to any other medicines that belong to sulphonylureas (such as glibenclamide, glipizide).

Use In Pediatrics

Contraindicated

RECLIDE 80MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Paediatric use may increase the risk of blood sugar fluctuations, and alternative options should be evaluated by a healthcare professional.

Use In Geriatrics

Use with Caution

RECLIDE 80MG TABLET should be used with caution in elderly patients, especially in those who take medicines such as CNS depressants or beta-blockers. Dosage adjustments may be needed based on kidney or liver function, nutritional status, and other medications taken.

Other Warnings for RECLIDE 80MG TABLET

Before taking RECLIDE 80MG TABLET inform your doctor if you:

• are malnourished, starved, on an irregular diet, or feeling weak
• perform extreme physical exercises
• have hormonal problems (Ex. disorders of the pituitary gland, adrenal cortex, or thyroid gland)

Who should not take [GBNKEYWORD

RECLIDE 80MG TABLET is not recommended for use if you:

• have type I diabetes (or insulin-dependent diabetes)
• have diabetic ketoacidosis (increased levels of sugar and ketone bodies in the blood)
• have a serious traumatic injury
• have G6PD deficiency (an inherited blood disorder)
• have porphyria (an inherited blood disorder)

Diet and Lifestyle Advice

Follow a Consistent and Balanced Diet

• Aim for regular meal timings, especially if you are taking a sulfonylurea like Gliclazide.
• Include foods rich in Fiber (whole grains, legumes, vegetables) to help maintain steady glucose levels.
• Choose low glycemic index (GI) foods such as oats, quinoa, lentils, and sweet potatoes.
• Avoid large quantities of sugary beverages, fried foods, and refined carbs.

 Incorporate Regular Physical Activity

• Light to moderate exercise such as walking, cycling may help improve overall energy levels and glucose metabolism.
• Try to maintain at least 30 minutes of activity on most days.
• Discuss with your doctor before starting any new fitness routine, especially if you’re at risk of low blood sugar.

Do not Skip Meals

• Skipping meals while using RECLIDE 80MG TABLET can lead to blood sugar drops.
• Always pair your dose with a meal, usually breakfast, to reduce fluctuations.

Maintain a Healthy Weight and Portion Control

• Portion control is key—even with healthy foods.
• Consider using smaller plates, avoiding second servings, and tracking what you eat in a food diary.

Prioritize Sleep and Stress Management

• Poor sleep and high stress can affect how your body processes glucose.
• Try to get 7–8 hours of sleep per night and practice stress-reducing activities such as deep breathing, nature walks, or hobbies.

Stay Hydrated and Avoid Excess Alcohol

• Drink plenty of water throughout the day.
• Alcohol may interfere with blood sugar levels and should be consumed only after medical guidance, especially when using sulfonylureas.

Drug - Drug interaction

1. Medicines That May Increase the Effect of RECLIDE 80MG TABLET

These drugs can enhance the blood sugar-lowering effect of RECLIDE 80MG TABLET and may increase the risk of hypoglycemia (low blood sugar):

• Antifungal medications (e.g., fluconazole)
• ACE inhibitors (e.g., enalapril, lisinopril)
• Certain antibiotics (e.g., sulfonamides, clarithromycin)
• Beta-blockers (e.g., propranolol, atenolol)
• MAO inhibitors (used for depression)
• Aspirin and other salicylates in high doses

2. Medicines That May Reduce the Effect of RECLIDE 80MG TABLET

• Corticosteroids (e.g., prednisone)
• Diuretics (e.g., hydrochlorothiazide, furosemide)
• Thyroid hormones
• Oral contraceptives
• Rifampicin (used for tuberculosis)

3. Medicines That May Mask Hypoglycemia Symptoms

• Beta-blockers and clonidine may hide typical symptoms of low blood sugar (such as tremors or palpitations), making it harder to recognize a drop in glucose levels.

Synopsis

More Information

RECLIDE 80MG TABLET vs Other Oral Medicines

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FAQs About RECLIDE 80MG TABLET

Q: Can RECLIDE 80MG TABLET be taken on an empty stomach?

A: It is generally advised to take this tablet with food to help maintain stable blood sugar levels.

Q: Is RECLIDE 80MG TABLET safe for long-term use?

A: When monitored regularly, RECLIDE 80MG TABLET may be used over extended periods. Regular check-ups and blood tests are advised.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. Skip the dose if it is almost time for the next dose, do not double up.

Q: Can I combine RECLIDE 80MG TABLET with other glucose-lowering products?

A: Combination use should only be done under the supervision of a healthcare provider to avoid hypoglycemia or other complications.

Q: What is RECLIDE 80MG TABLET used for?

A: RECLIDE 80MG TABLET is an antidiabetic medicine used in the management of type II diabetes mellitus when diet, exercise, and lifestyle changes alone do not result in an adequate response.

Q: How and when should I take RECLIDE 80MG TABLET?

A: Take RECLIDE 80MG TABLET before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

Q: How long should I take RECLIDE 80MG TABLET?

A: You need to take RECLIDE 80MG TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.

Q: Can I stop taking RECLIDE 80MG TABLET without consulting your doctor?

A: No. You should not stop taking RECLIDE 80MG TABLET without consulting your doctor because it may lead to a reversal of symptoms. If you feel better after using RECLIDE 80MG TABLET, consult your doctor for advice. Your doctor might reduce the dose gradually before discontinuation of therapy.

Q: Will taking a higher dose of RECLIDE 80MG TABLET be more effective?

A: No, taking a higher dose of RECLIDE 80MG TABLET will not be effective, rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Q: Can I take medication for high blood pressure along with RECLIDE 80MG TABLET?

A: No. It is not advisable to take medicines to control blood pressure while taking RECLIDE 80MG TABLET without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with RECLIDE 80MG TABLET, as they have known interactions with RECLIDE 80MG TABLET.

Q: What should I do if I experience low blood sugar after taking RECLIDE 80MG TABLET?

A: Low blood sugar is a common side effect of taking RECLIDE 80MG TABLET. Try to have sugar-rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If you have not reached the optimum level, take another sugary snack or drink and check the blood sugar again. In cases of persistently low blood sugar levels, consult your doctor immediately.

Q: Can RECLIDE 80MG TABLET cause dizziness?

A: Yes. Dizziness is a common side effect of using RECLIDE 80MG TABLET If you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuously for a long time after taking RECLIDE 80MG TABLET.

Q: Can RECLIDE 80MG TABLET be taken with insulin?

A: Co-administration of RECLIDE 80MG TABLET with insulin is considered risky as it increases the chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.

References

1. K.D. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270-272.

2. Shinnya Miwa, Hirotaka Watada, Ohmura chie and Yasushi Tanaka. Efficacy and Safety of Once Daily Gliclazide (20 mg/day) Compared with Nateglinide. ScienceDirect.com. August 2004. [Accessed on 21st July 2025] 

3. Les Laboratoires Servier. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 21st July 2025] 

4. Accord. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 21st July 2025] 

5. Accord. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 21st July 2025] 

6. Balkanpharma-Dupnitsa AD. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed on 21st July 2025] 

7. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 21st July 2025] 

Useful Diagnostic Tests

• Random Blood Sugar (RBS)
• Fasting Blood Sugar (FBS)
• Post Prandial Blood Sugar (PPBS)
• Sugar Risk Package
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 21 Jul 2025 | 04:01 PM(IST)