Rebagen 100mg Tablet 10'S
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Introduction About REBAGEN 100MG TABLET
REBAGEN 100MG TABLET contains Rebamipide which belongs to the group of medicines called Gastroprotective agents. It is used in the management of gastric ulcers and gastric mucosal lesions (erosion, bleeding, redness and edema) in the following conditions such as acute gastritis, acute exacerbation of chronic gastritis (a sudden inflammation or swelling in the lining of the stomach).
Gastric ulcer are open sores that develop on the inside lining of stomach. Symptoms include burning stomach pain, feeling of fullness, bloating or belching, intolerance to fatty foods, heartburn, nausea.
Inform your doctor before taking REBAGEN 100MG TABLET if you are pregnant or breastfeeding. Consult your doctor for advice.
Safety and effectiveness of REBAGEN 100MG TABLET in children has not been established yet. It should be used with caution in elderly patients above 65 years of age. Consult your doctor for advice.
The most common side effects of taking REBAGEN 100MG TABLET are constipation, bloating, nausea, vomiting, diarrhea. Consult your doctor if side effects do not show improvement.
Uses Of REBAGEN 100MG TABLET
It is used to manage:
- gastric ulcer
- gastric mucosal lesions (acute gastritis and acute exacerbation of chronic gastritis)
How REBAGEN 100MG TABLET Works
REBAGEN 100MG TABLET belongs to mucosal protective agent which increases the synthesis of prostaglandin, a chemical messenger which improves healing of the ulcer.
How to use REBAGEN 100MG TABLET
Take REBAGEN 100MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of REBAGEN 100MG TABLET
Common
- constipation
- bloating
- nausea and vomiting
- diarrhea
- rashes, itching
Rare
- menstrual problems
- edema
- taste change
- dry mouth
- dizziness, drowsiness
- burping, heartburn
- abdominal pain
Stop taking REBAGEN 100MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- high fever and rashes
- hypersensitivity reactions
- leukopenia, thrombocytopenia (low white blood cells and platelet count)
- liver disfunction and jaundice
How To Manage Side Effects
Constipation:
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise regularly. Consult your doctor if symptoms do not show improvement.
Nausea and Vomiting:
Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if symptoms do not show improvement.
Diarrhoea:
Drink lots of water or fruit juice to keep yourself hydrated. Consult your doctor if symptoms do not show improvement.
Warning & Precautions
Pregnancy
Safety and effectiveness of REBAGEN 100MG TABLET in pregnant women has not been established yet so it will be given by your doctor only if the benefits overweigh the risk. Consult your doctor before taking it.
Breastfeeding
REBAGEN 100MG TABLET is not recommended for use in breastfeeding women as it will be excreted in the breastmilk. Breastfeeding should be stopped if undergoing this> management. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or use machines while taking REBAGEN 100MG TABLET as it can make you dizzy or sleepy.
Allergy
Do not take REBAGEN 100MG TABLET if you are allergic or hypersensitive to Rebamipide or any other ingredients of this medicine.
Others
Use in pediatrics:
Safety and effectiveness of REBAGEN 100MG TABLET in children has not been established yet. Consult your doctor before taking the medicine.
Use in geriatrics:
REBAGEN 100MG TABLET should be used with caution in elderly patients above 65 years of age as they are more sensitive to gastrointestinal problems. Consult your doctor before taking the medicine.
Interactions
A. Drug-Drug interactions:
Before taking REBAGEN 100MG TABLET inform your doctor if you are taking any of the following medicine any other medicinal products, over-the-counter medicines, and dietary supplements as well as other prescription medicines.
Overdosage:
If you or anyone else accidentally take too much of REBAGEN 100MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Rebamipide |
| Pharmacological Category | : | Gastroprotective agents |
| Therapeutic Indication | : | Gastric ulcer, Gastric mucosal lesions |
| Dosage Forms | : | Tablet, Eye drops |
More Information
- Keep REBAGEN 100MG TABLET out of reach of children
- Store below 30°C
FAQs About REBAGEN 100MG TABLET
What is REBAGEN 100MG TABLET used for?
REBAGEN 100MG TABLET is used in the management of gastric ulcers and gastric mucosal lesions (erosion, bleeding, redness and edema) in the following conditions such as acute gastritis and acute exacerbation of chronic gastritis (a sudden inflammation or swelling in the lining of the stomach).
Can REBAGEN 100MG TABLET be used in pregnant women?
Safety and effectiveness of REBAGEN 100MG TABLET in pregnant women has not been established yet so it will be given by your doctor only if the benefits overweigh the risk. Consult your doctor before taking it.
Can I drive while taking REBAGEN 100MG TABLET?
Do not drive or use machines while taking REBAGEN 100MG TABLET as it can make you dizzy or sleepy, make sure you know how the medicine works for you before driving. Consult your doctor for advice.
Can REBAGEN 100MG TABLET be used in children?
Safety and effectiveness of REBAGEN 100MG TABLET in children and infants has not been established yet. Consult your doctor before taking it for more information.
How does REBAGEN 100MG TABLET work?
REBAGEN 100MG TABLET belongs to mucosal protective agent which increases the synthesis of prostaglandin, a chemical messenger which improves healing of the ulcer.
References
1. Goodman. Gilman. Pharmacotherapy of gastric acidity, peptic ulcers. The pharmacological basis of therapeutics. Twelfth Edition. 2010. Page – 1317.
2. Mohan H Kudur and Manjunath Hulmani. Rebamipide: A Novel Agent in the Treatment of Recurrent Aphthous Ulcer and Behcet's Syndrome. [Accessed on 20th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778773/
3. Yuji Naito. Rebamipide: A gastrointestinal protective drug with pleiotropic activities. [Accessed on 20th July 2022] https://www.researchgate.net/publication/44653968_Rebamipide_A_gastrointestinal_protective_drug_with_pleiotropic_activities
4. Korea Otsuka Pharmaceutical Co., Ltd. Rebamipide. [Accessed on 20th July 2022] https://otsuka.pk/uploads/files/Mucosta_Leaflet.pdf
5. Rad-ar. Rebamipide. [Revised in February 2016] [Accessed on 20th July 2022] https://www.rad-ar.or.jp/siori/english/search/result?n=34818
6. MIMS. Rebamipide. [Accessed on 20th July 2022] https://www.mims.com/philippines/drug/info/mucosta?type=full, https://www.mims.com/india/drug/info/rebamipide?type=full&mtype=generic
7. Rebamipide. Mayoclinic. [Revised on June 2022] [Accessed on 20th July 2022] https://www.mayoclinic.org/diseases-conditions/peptic-ulcer/symptoms-causes/syc-20354223
8. Rebamipide. Healthline. [Revised on August 2016] [Accessed on 20th July 2022] https://www.healthline.com/health/gastritis-acute
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