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Introduction About RAZO 20MG TABLET
RAZO 20MG TABLET contains Rabeprazole which belongs to the group of medicines called Proton pump inhibitors. It is used to manage Gastro-esophageal Reflux Disease (GERD), peptic ulcer and Zollinger-Ellison syndrome (tumours in the pancreas causing the stomach to secrete more acid).
GERD is a chronic digestive disease in which the stomach acid frequently flows into the oesophagus leading to the irritation of lining of the food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort.
Peptic ulcers are painful sores that develop on the linings of the stomach, oesophagus and/or intestines. Symptoms include stomach pain, flatulence, indigestion, vomiting and fatigue.
Take it preferably before meals or as directed by the physician. Before taking RAZO 20MG TABLET inform your doctor if you have any liver problems. You must also inform your doctor if you have vitamin B12 deficiency, osteoporosis or any tumors in your stomach.
Do not take RAZO 20MG TABLET if you are pregnant or breastfeeding without consulting your doctor. The most common side effects are oral sores, constipation, indigestion, stomach pain, headache and dizziness. Consult your doctor if any of the side effect troubles you.
You must also inform your doctor immediately if you experience severe uncontrollable diarrhea with stomach pain or tenderness after taking RAZO 20MG TABLET.
Uses Of RAZO 20MG TABLET
Manages,
- Gastro-Esophageal Reflux Disease
- Peptic ulcers
- Zollinger-Ellison syndrome
Benefits of RAZO 20MG TABLET
- Reduces stomach acid to relieve discomfort linked to excess acid production.
- Supports symptom relief for acid reflux and related heartburn.
- Helps heal stomach and intestinal ulcers by lowering acid levels.
- Manages conditions like GERD and Zollinger-Ellison syndrome, improving overall digestive health.
- Promotes digestive comfort by balancing acid secretion and reducing irritation
How RAZO 20MG TABLET Works
How Rabeprazole Blocks Proton Pumps
Rabeprazole, the active ingredient in Razo 20mg Tablet, targets and irreversibly inhibits proton pumps (H+/K+ ATPase) in stomach parietal cells, which are responsible for acid secretion.
Acid Secretion Suppression and Increased Stomach pH
By blocking the final step of acid production, Razo 20mg reduces gastric acid release, leading to a higher stomach pH and relief from acid-related discomfort.
Conversion to Active Form in Acidic Environment
Rabeprazole is converted into an active sulfenamide intermediate in acidic conditions, which then forms covalent bonds with proton pumps to inhibit their activity.
Sustained Acid Control Through Irreversible Binding
The irreversible binding prevents acid secretion until new proton pumps are synthesized, providing prolonged acid suppression and symptom relief.
How to use RAZO 20MG TABLET
How to Take Razo 20mg Tablet
Take one tablet daily, preferably in the morning on an empty stomach, at least 30 minutes before eating. Swallow the tablet whole with water without chewing or crushing it.
Dosage Guidelines
Follow the dose and duration as prescribed by the healthcare provider, tailored to individual condition and response. Do not alter dose or discontinue medication without consulting your doctor.
Important Administration Tips
Maintain regular timing each day to ensure consistent effect. Avoid late-night eating, spicy or fatty foods, caffeine, and alcohol to optimize symptoms relief.
Side Effects Of RAZO 20MG TABLET
Common
- mouth sores
- difficulty in sleeping
- headache, dizziness
- stomach pain, diarrhoea, flatulence, nausea, vomiting or constipation
- aches or back pain
- polyps in the stomach
When to consult a doctor:
- allergic reactions (such as skin rash, itching, swelling of your face, difficulty in breathing and low blood pressure)
- skin rashes on sun exposed areas
- signs of frequent infections (such as chills, sore throat and fever)
- painful ulcers in the mouth or throat
- bruising or bleeding easily
- severe watery or bloody diarrhoea with fever, stomach pain or tenderness
Warning & Precautions
Pregnancy
ContraindicatedRAZO 20MG TABLET is generally not advised for use in pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedRAZO 20MG TABLET is generally not advised for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel sleepy after taking RAZO 20MG TABLET.
Liver
Use with CautionRAZO 20MG TABLET should be used cautiously in patients who have or ever had any liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take RAZO 20MG TABLET if you are allergic to Rabeprazole or to any other proton pump inhibitors (such as omeprazole, esomeprazole).
Use In Pediatrics
ContraindicatedRAZO 20MG TABLET is not advised for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before administration.
Use In Geriatrics
Use with CautionRAZO 20MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Other Warnings for RAZO 20MG TABLET
Before taking RAZO 20MG TABLET, inform your doctor if you:
- have a tumor in your stomach
- had a skin reaction after management with a medicine similar to RAZO 20MG TABLET
- have osteoporosis (weak bones)
- are going to have a specific blood test (Chromogranin A)
Drug - Drug interaction
Acid Suppression Effect on Drug Absorption
Razo 20mg Tablet may reduce the absorption of drugs needing an acidic environment such as ketoconazole, itraconazole, digoxin, and certain anticancer drugs.
Contraindicated Combinations
Avoid concomitant use with rilpivirine (an HIV medication) as acid suppression reduces rilpivirine plasma levels, risking treatment failure.
Interaction with Antacids and Supplements
Antacids (magnesium hydroxide, aluminum hydroxide), calcium, and iron supplements may interact but usually require temporal separation for safe use.
Synopsis
| Drug | : | Rabeprazole |
| Pharmacological Category | : | Proton Pump Inhibitors |
| Therapeutic Indication | : | GERD, Peptic ulcer, Zollinger-Ellison Syndrome |
| Dosage Forms | : | Tablet, Capsule, Powder, Injection, Infusion |
More Information
Comparison with similar medicines
|
Feature |
Rabeprazole |
Pantoprazole |
Omeprazole |
Lansoprazole |
Esomeprazole |
|
Onset of Action |
Fastest onset; rapid activation |
Moderate onset |
Moderate onset |
Moderate onset |
Faster than omeprazole |
|
Acid Suppression |
Superior acid suppression, esp. night-time |
Effective but less than rabeprazole |
Effective but less potent |
Effective |
Highly effective |
|
Duration of Effect |
Prolonged acid suppression |
Moderate duration |
Moderate duration |
Moderate duration |
Prolonged duration |
|
Metabolism |
Mainly non-enzymatic; less CYP2C19 dependent |
Metabolized by CYP2C19 |
Heavily metabolized by CYP2C19 |
Metabolized by CYP2C19 |
Metabolized by CYP2C19 |
|
Drug Interaction Potential |
Lower risk compared to omeprazole, lansoprazole |
Lower risk |
Higher risk |
Higher risk |
Moderate risk |
|
Common Uses |
GERD, peptic ulcers, Zollinger-Ellison syndrome |
GERD, ulcer treatment |
GERD, ulcers |
GERD, ulcers |
GERD, erosive esophagitis |
Did you know?
- Razo 20mg Tablet contains Rabeprazole, a proton pump inhibitor (PPI) that blocks the proton pumps in the stomach lining responsible for acid production
- It is recommended to take the tablet at least 30 minutes before meals for optimal effect.
- The drug’s action helps improve overall digestive health by reducing irritation caused by excess acid.
- Long-term use may require monitoring for potential vitamin B12 deficiency or bone health issues.
Areas for Consideration
- Review personal and family medical history before purchase
- Understand alternative dosage forms and medicine substitutes
- Consult health experts for elderly, pregnant, or breastfeeding individuals prior to selection
- Be aware of long-term usage considerations (such as nutrient absorption)
FAQs About RAZO 20MG TABLET
Q: What are the uses of RAZO 20MG TABLET?
A: RAZO 20MG TABLET is used to manage Gastro-esophageal Reflux Disease (GERD), peptic ulcer and Zollinger-Ellison syndrome (tumours in the pancreas causing the stomach to secrete more acid).
Q: How RAZO 20MG TABLET works?
A: RAZO 20MG TABLET is a proton pump inhibitor. It reduces the amount of acid produced in the stomach by blocking the actions of an enzyme called H+ K+ ATPase (also known as proton pump) which is present in the lining of the stomach walls. As a result, it reduces the chances for acid reflux into the oesophagus, heals peptic ulcers and esophageal lesions and manages its recurrence.
Q: How long will it take for RAZO 20MG TABLET to manage my disease?
A: The time taken for healing depends on the severity of the disease. You may notice improvement in your condition within 1-2 days of therapy with RAZO 20MG TABLET. However, it may take several weeks for RAZO 20MG TABLET to completely heal the ulcers.
Q: When should I take RAZO 20MG TABLET?
A: RAZO 20MG TABLET should be taken on an empty stomach at mornings. It can also be taken before a meal. Swallow RAZO 20MG TABLET with a glass of water.
Q: What are the long-term side effects of RAZO 20MG TABLET?
A: Taking RAZO 20MG TABLET especially over the time of a year can slightly increase the risk of hip, wrist, or spine fracture. Inform your doctor if you suffer from osteoporosis or if you are taking corticosteroids which can increase the risk of osteoporosis. It may also cause vitamin B12 deficiency and low magnesium levels in the blood.
Q: Can I stop taking RAZO 20MG TABLET once my symptoms subside?
A: Do not stop taking RAZO 20MG TABLET without consulting your doctor even if you feel better during the midway of the therapy. Make sure to take RAZO 20MG TABLET for the stipulated duration recommended by your doctor to achieve complete healing of ulcers.
Q: What is the best time to take RAZO 20MG TABLET?
A: RAZO 20MG TABLET should be taken while you are on empty stomach in the morning. It can also be taken before a meal.
Q: What to do if I forgot to take a dose of RAZO 20MG TABLET?
A: If you have missed a dose of RAZO 20MG TABLET, take it as soon as you remember. However, if it is time for the next dose of RAZO 20MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of RAZO 20MG TABLET to compensate the missed ones.
Q: What precautions should be followed while taking RAZO 20MG TABLET?
A: Before taking RAZO 20MG TABLET inform your doctor if you have any liver problems. You must also inform your doctor if you have vitamin B12 deficiency, osteoporosis or any tumors in your stomach. Do not take RAZO 20MG TABLET if you are pregnant or breastfeeding without consulting your doctor. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail. You must also inform your doctor immediately if you experience severe uncontrollable diarrhea with stomach pain or tenderness after taking RAZO 20MG TABLET.
Q: Can I consume alcohol while taking RAZO 20MG TABLET?
A: Avoid consumption of alcohol while taking RAZO 20MG TABLET as it could aggravate your ulcers and delays the healing process.
Q: Can I take RAZO 20MG TABLET daily?
A: Take RAZO 20MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggest whether can you take RAZO 20MG TABLET every day or not.
Q: Can the use of RAZO 20MG TABLET affect the liver?
A: Yes. RAZO 20MG TABLET may affect the way your liver work. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
Q: Can RAZO 20MG TABLET be taken during pregnancy?
A: RAZO 20MG TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
References
1. KD. Tripathi. Drugs for Peptic Ulcer and GERD. Essentials of medical pharmacology. Seventh edition. 2013. Page – 653
2. Seiichi Hayato, Setsuo Hasegawa, Seiichiro Hojo, Hiroki Okawa, Hiroaki Abe, Nobuyuki Sugisaki, Masahiro Munesue, Yukio Horai, Akihiro Ohnishi. Dose-response relationships of rabeprazole 5, 10, 20, and 40 mg once daily on suppression of gastric acid secretion through the night in healthy Japanese individuals with different CYP2C19 genotypes. NIH National Library of Medicine, National Center for biotechnology information. Pubmed.gov. May 2012. [Accessed on 6th January 2026]. 
3. Eisai GmbH. Electronic Medicines Compendium (EMC). Revised in May2021. [Accessed on 6th January 2026]. 
4. Eisai R&D Management Co., Ltd. U.S. Food and Drug Administration. [Revised in December 2014]. [Accessed on 6th January 2026].
Useful Diagnostic Tests
- Ultrasound
- Endoscopy
- Liver Function Test
- Complete Blood Count
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