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Introduction About RAIKI EYE DROPS
RAIKI EYE DROPS contains Netarsudil, which belongs to the group of medicines known as Rho Kinase Inhibitor. RAIKI EYE DROPS is indicated for reduction of elevated intraocular pressure in adult patients with primary open-angle glaucoma or ocular hypertension.
Primary open-angle glaucoma is a type of glaucoma that develops over a period of time due to clogging of drainage channels of the eye. Glaucoma is an irreversible and progressive condition in which the optic nerve gets damaged due to several reasons, such as increased pressure caused by fluid buildup in the front region of the eye. Ocular hypertension can be defined as high intraocular (inside the eye) pressure due to disturbance in balance between production and outflow of aqueous humour (fluid inside the eye).
Inform your doctor before using RAIKI EYE DROPS if you have trauma to the eye, planned eye surgery, dry eyes, concurrent eye disease, or if you have ocular epithelial surface disruption, as the risk of bacterial keratitis (bacterial infection of the outer layer of the eye) is increased in such cases.
RAIKI EYE DROPS is not recommended for use in pregnant women unless clearly necessary. Consult your doctor before using. RAIKI EYE DROPS should be used with caution in breast-feeding women. Consult your doctor before using it.
RAIKI EYE DROPS is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before using it.
If you wear contact lenses, they should be removed prior to instillation of this medicine and can be reinserted 15 minutes following its administration.
RAIKI EYE DROPS may cause some side effects such as conjunctival hyperaemia (dilation of vessels of conjunctiva due to inflammation), corneal verticillate (condition in which corneal deposits form a faint golden-brown whorl pattern), conjunctival haemorrhage, instillation site pain, and erythema. Consult your doctor immediately in case any of the above side effects worsen.
Uses Of RAIKI EYE DROPS
- Used to reduce elevated intraocular pressure in adult patients with primary open-angle glaucoma or ocular hypertension
How RAIKI EYE DROPS Works
RAIKI EYE DROPS is a rho kinase inhibitor that works by reducing intraocular pressure (IOP) by increasing the outflow of aqueous humour (transparent fluid in the eye, which is important for maintaining pressure inside the eye and nourishment of our natural lens) through relaxation of the trabecular meshwork.
How to use RAIKI EYE DROPS
Instil RAIKI EYE DROPS into the affected eye as directed by your doctor. RAIKI EYE DROPS is for ophthalmic use only. Do not inject or swallow the medicine. Wash your hands before using and avoid touching the nozzle or dropper while using the medicine, as it may contaminate the medicine.
Your doctor will decide the exact dose and duration according to your disease condition, body weight, and age. The tip of the dispensing container should avoid contacting the eye, surrounding structures, fingers, or any other surface to avoid contamination of the solution.
Side Effects Of RAIKI EYE DROPS
Common
- conjunctival hyperaemia (dilation of vessels and redness of conjunctiva due to inflammation)
- corneal verticillata (condition in which corneal deposits form a faint golden-brown whorl pattern)
- conjunctival haemorrhage
- eye dryness, breaks in protective surface fluid layer of eye
- eye discharge, itching in eyes or eyelids, eye irritation
- pain in the eye
- feeling of grittiness in the eye
- sensitivity to light
- instillation site pain, discomfort, and erythema
- reduced visual acuity
- blurred vision, swelling around eye and eyelid
- headache
- staining of the cornea due to dye
- increased tear formation
- punctate keratitis (an eye disorder caused by death of cells on the corneal surface)
- conjunctival oedema (swelling of the membrane that covers the white part of the eye)
- foreign body sensation in eyes
- corneal opacity (loss of transparency of the cornea) and decreased vision
- increase in intraocular pressure
- spots or patches of eye redness
Uncommon
- inflammation of iris (coloured part of eye), budging of iris
- eyelash growth
- eye diseases related to diabetes
- blindness
- cataract
- small, coloured spots on the eye surface
- glassy eyes
- loss of eyelashes, eyebrows
- tiredness
- increased allergic symptoms
- dizziness
- nasal discomfort, pain
- rash, inflammation, itching of skin, picking of skin
- inflammation of cartilage
- ocular hyperaemia
- corneal or eyelid disorder
- conjunctival follicles
- meibomian gland dysfunction
- corneal pigmentation
- lenticular opacities
- non-infective conjunctivitis
- abnormal sensation in the eye
- episcleral hyperaemia
- refraction disorder
- anterior chamber flare, inflammation
- eczema eyelids
- iris adhesions
- iris bombe (change in position of iris to the lens)
- visual impairment
- corneal dystrophy
- oedema, paraesthesia
- optic nerve cup/disc ration increased
- allergic dermatitis, contact dermatitis
- lichenification, petechiae
Rare
Stop using RAIKI EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- development of eye infections or eye reactions such as conjunctivitis, eyelid reactions
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel dizziness. Avoid alcohol consumption, as it aggravates dizziness. Contact your doctor if dizziness worsens.
Headache
Rest and relax. Drink plenty of water and electrolytes. Apply a pain-relieving balm on the head if needed. Do not consume alcohol. Contact your doctor if your headache does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredRAIKI EYE DROPS is not recommended for use in pregnant women unless clearly necessary. Consult your doctor before using it.
Breastfeeding
Consult your doctorIt is unknown whether RAIKI EYE DROPS is excreted in human milk, consult your doctor before using the medicine. Your doctor will decide whether to discontinue breast-feeding or to discontinue the therapy by taking the account of breast-feeding for the child and the benefit of therapy for the woman.
Driving and Using Machines
Use with CautionRAIKI EYE DROPS may cause blurred vision, which can affect your ability to drive and operate machines. Do not drive or operate machines until symptoms are cleared.
Allergy
ContraindicatedDo not use RAIKI EYE DROPS if you are allergic to Netarsudil or benzalkonium chloride and other ingredients of this medicine.
Use In Pediatrics
Consult your doctorThe safety and efficacy of RAIKI EYE DROPS in children and adolescents under the age of 18 years have not been established. Consult your doctor before using it.
Use In Geriatrics
SafeRAIKI EYE DROPS can be used in elderly patients. Consult your doctor before using it.
Others
Before using RAIKI EYE DROPS, inform your doctor if you have:
- trauma to the eyes
- eye surgery
- dry eyes
- concurrent eye disease
- disruption of ocular surface
Interactions
A. Drug-Drug interactions:
Before using RAIKI EYE DROPS, inform your doctor if you are taking or using any prescription medicine, non-prescription medicine, or any herbal medicine.
Overdosage:
In case you or anybody else uses too much of RAIKI EYE DROPS, wash your eyes immediately and consult your doctor. In case of accidental ingestion, contact your physician immediately.
Synopsis
| Drug | : | Netarsudil |
| Pharmacological Category | : | Rho Kinase Inhibitor |
| Therapeutic Indication | : | Elevated Intraocular Pressure (in Ocular Hypertension or Open Angle Glaucoma) |
| Dosage Forms | : | Eye Drops |
More Information
Storage
- Keep RAIKI EYE DROPS out of reach of children
- Store in a refrigerator at 2-8°C
FAQs About RAIKI EYE DROPS
Q: What is RAIKI EYE DROPS?
A: RAIKI EYE DROPS contains Netarsudil, which belongs to a group of medicines known as Rho-kinase inhibitors. It is indicated for the reduction of elevated intraocular pressure in adult patients with primary open-angle glaucoma or ocular hypertension.
Q: What is the mechanism of RAIKI EYE DROPS?
A: RAIKI EYE DROPS is a rho kinase inhibitor. It works by reducing IOP by increasing the outflow of aqueous humour (transparent fluid in the eye, which is important for maintaining pressure inside the eye and nourishment of our natural lens) through relaxation of the trabecular meshwork. Hence, reducing intraocular pressure.
Q: Can I use RAIKI EYE DROPS with other eye medications?
A: If you are using other eye medications as well, then there must be at least a 15-minute gap between the usage of both. Consult your doctor before using RAIKI EYE DROPS with other medications.
Q: Can I operate machinery or drive after using RAIKI EYE DROPS?
A: No, as RAIKI EYE DROPS may cause blurring of vision or decreased visual acuity, which can affect your ability to drive and operate machinery.
Q: Can I use contact lenses while using RAIKI EYE DROPS?
A: Yes, but contact lenses should be removed before using RAIKI EYE DROPS and should be reinserted only after 15 minutes of instillation.
Q: How to use RAIKI EYE DROPS?
A: Instill RAIKI EYE DROPS into the affected eye as directed by your doctor. RAIKI EYE DROPS is for ophthalmic use only. Do not inject or swallow the medicine. Wash your hands before using and avoid touching the nozzle or dropper while using the medicine, as it may contaminate the medicine.
Q: Is RAIKI EYE DROPS safe during pregnancy?
A: RAIKI EYE DROPS is not recommended for use in pregnant women unless clearly necessary. Consult your doctor before using it.
Q: Who should not use RAIKI EYE DROPS?
A: Do not use RAIKI EYE DROPS if you are allergic to Netarsudil or benzalkonium chloride and other ingredients of this medicine.
Q: Can RAIKI EYE DROPS be used in kids?
A: The safety and efficacy of RAIKI EYE DROPS in children and adolescents under the age of 18 have not been established. Consult your doctor before using it.
Q: What precautions must be taken while using RAIKI EYE DROPS?
A: Before using RAIKI EYE DROPS, inform your doctor if you have trauma to the eyes, eye surgery, dry eyes, concurrent eye disease, or disruption of the ocular surface.
References
1. Robert J. Kizior, Keith J. Hodgson. Antiglaucoma agents. Saunders Nursing Drug Handbook 2021. 29th edition. 2021. Page- 88.
2. Preeti Patel, Bhupendra C. Patel. Netarsudil Ophthalmic Solution. National Institute of Health. NLM. National Centre for Biotechnology. May 2022. [Accessed on 24th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK572105/#article-133789.s5
3. Sheridan M. Hoy. Netarsudil Ophthalmic Solution 0.02%: First Global Approval. National Institute of Health. NLM. National Centre for Biotechnology. March 2018. [Accessed on 24th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK572105/#article-133789.s5
4. Mansi Batra, Sumeet Gupta, Anroop Nair, and Meenakshi Dhanawat. Netarsudil: A new ophthalmic drug in the treatment of chronic primary open angle glaucoma and ocular hypertension. European Journal of Ophthalmology. April 2021. [Accessed on 24th August 2024] https://www.researchgate.net/publication/350796642_Netarsudil_A_new_ophthalmic_drug_in_the_treatment_of_chronic_primary_open_angle_glaucoma_and_ocular_hypertension
5. Aerie Pharmaceuticals. Food and Drug Administration. [Revised in December 2017] [Accessed on 24th August 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208254lbl.pdf
6. Aerie Pharmaceuticals Ireland, Limited. European Medicines Agency. [Revised in November 2019] [Accessed on 24th August 2024] https://www.ema.europa.eu/en/documents/product-information/rhokiinsa-epar-product-information_en.pdf
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