New Revised MRP, 100% GST benefit passed Pyrigesic 1000 Tablet 10'S
Netmeds First Membership
Quick Links
Introduction About PYRIGESIC 1GM TABLET
PYRIGESIC 1GM TABLET contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to relieve mild to moderate pain (including headaches, backache, toothache, severe nerve pain, sore throat, period pain, low back and leg pain, muscle, connective tissue and joint pain, symptomatic relief of sprains, strain, joint swelling and stiffness). It is also used to lower fever (high body temperature) and relieve cold or flu symptoms.
Before taking PYRIGESIC 1GM TABLET, inform your doctor if you or your child have liver or kidney problems or any allergies. It should be used with caution in patients with liver problems due to alcohol to manage the risk of liver damage.
PYRIGESIC 1GM TABLET should be used with caution in pregnant women only if clearly advised by the doctor and can be used in breastfeeding women. PYRIGESIC 1GM TABLET is not recommended for use in children less than 10 years of age and should be used with caution in elderly patients.
Consult your doctor if you experience any side effects or unusual effects during management with PYRIGESIC 1GM TABLET.
Uses Of PYRIGESIC 1GM TABLET
- relieves mild to moderate pain (such as headache, toothache, joint pain)
- lowers fever and relieves the symptoms of cold or flu
How PYRIGESIC 1GM TABLET Works
PYRIGESIC 1GM TABLET relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
How to use PYRIGESIC 1GM TABLET
Take PYRIGESIC 1GM TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow PYRIGESIC 1GM TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned on the label. Consume the medicine immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the condition.
Side Effects Of PYRIGESIC 1GM TABLET
Rare
- reduced white blood cells (infections are more likely to occur)
Stop taking PYRIGESIC 1GM TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (swelling of the hands, feet, ankles, face, lips or throat which may cause trouble swallowing or breathing, an itchy, lumpy rash or nettle rash, runny nose)
Warning & Precautions
Pregnancy
PYRIGESIC 1GM TABLET should be used with caution in pregnant women only if considered clearly necessary. Your doctor may use the lowest possible dose to reduce the pain and fever only for a shorter duration in pregnant women. Consult your doctor before taking PYRIGESIC 1GM TABLET.
Breastfeeding
PYRIGESIC 1GM TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
PYRIGESIC 1GM TABLET has no influence on the ability to drive and operate machinery.
Alcohol
PYRIGESIC 1GM TABLET should be used with caution in patients with chronic alcoholism. Consult your doctor before taking it.
Kidney
PYRIGESIC 1GM TABLET should be used with caution in patients with severe kidney problems. Consult your doctor before taking it.
Liver
PYRIGESIC 1GM TABLET should be used with caution in patients with severe liver problems or liver problems due to alcohol. Consult your doctor before taking it.
Allergy
Do not take PYRIGESIC 1GM TABLET if you are allergic to Paracetamol or any other ingredients of this medicine.
Others
Before taking PYRIGESIC 1GM TABLET, inform your doctor if you:
- have sepsis (circulation of bacteria and their toxins in the blood leading to organ damage)
- are malnourished
Use in pediatrics:
PYRIGESIC 1GM TABLET is not recommended for use in children less than 10 years of age. It can be used in children and adolescents aged above 10 and your child’s doctor may adjust the dose based on the child’s age and body weight. Consult your child’s doctor for advice.
Use in geriatrics:
PYRIGESIC 1GM TABLET should be used with caution in elderly patients. Consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking PYRIGESIC 1GM TABLET, inform your doctor if you are taking any of the following medicines:
- other medicines containing paracetamol
- medicines to manage nausea and vomiting (Ex. metoclopramide, domperidone)
- cholestyramine (used to control blood lipid levels)
- warfarin (used for managing blood clots)
- medicines used to manage bacterial infections (Ex. rifampicin, flucloxacillin, chloramphenicol)
Overdosage:
If you or anyone else accidentally takes too much of PYRIGESIC 1GM TABLET, consult your doctor immediately or visit the nearby hospital, even if you feel well, as it can cause delayed, serious liver damage.
Synopsis
| Drug | : | Paracetamol |
| Pharmacological Category | : | Para aminophenol derivative |
| Therapeutic Indication | : | Pain, Fever |
| Dosage Forms | : |
Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection |
More Information
- Keep PYRIGESIC 1GM TABLET out of reach of children
- Store below 25°C
FAQs About PYRIGESIC 1GM TABLET
Q: What is the use of PYRIGESIC 1GM TABLET?
A: PYRIGESIC 1GM TABLET is commonly used to relieve mild to moderate pain and reduce fever. It contains paracetamol (acetaminophen) and is often used for conditions like headaches, muscle aches, toothaches, associated with various illnesses.
Q: What happens if I take PYRIGESIC 1GM TABLET?
A: PYRIGESIC 1GM TABLET contains a medicine called paracetamol which is an analgesic and antipyretic agent. Following administration, it works by blocking the release of certain chemicals called prostaglandins in the body which is responsible for causing pain and inflammation. Paracetamol also manages the release of such chemicals in the hypothalamus of the brain which helps in controlling fever.
Q: Can I take two doses of PYRIGESIC 1GM TABLET in a day?
A: The dosage of PYRIGESIC 1GM TABLET is decided by your physician. However, studies have shown that taking paracetamol once in every 4-6 hours significantly reduced fever and body pains.
Q: Can we use PYRIGESIC 1GM TABLET for cold?
A: PYRIGESIC 1GM TABLET could be used in the management of sore throat and body pains that is associated with common cold. It contains a medicine called paracetamol which is commonly used to relieve mild to moderate pain, like headaches, muscle aches, toothaches, and fever associated with various illnesses.
Q. Can I take PYRIGESIC 1GM TABLET as often as required?
A: The dosage of PYRIGESIC 1GM TABLET and duration of the therapy would be decided by your doctor. It is usually not recommended to take more than 4 doses of PYRIGESIC 1GM TABLET in a day. Leave a time gap of 4-6 hours, between each dose.
Q: Is PYRIGESIC 1GM TABLET a strong medicine?
A: PYRIGESIC 1GM TABLET is relatively an effective medicine in controlling fever and body pain. It is typically used for mild to moderate pain relief and fever reduction. However, it should be used as directed, and exceeding the recommended dosage can lead to adverse effects.
Q: When would PYRIGESIC 1GM TABLET start working?
A: It takes around 30 minutes for you to feel better after taking PYRIGESIC 1GM TABLET.
Q: Can I take PYRIGESIC 1GM TABLET and ibuprofen together?
A: It is generally advisable to avoid taking PYRIGESIC 1GM TABLET (paracetamol) and ibuprofen together unless recommended by a healthcare professional. Mixing these medications can increase the risk of side effects and potential harm to the liver and stomach.
Q: When should we discontinue the use of Paracetamol?
A: Discontinue the use of Paracetamol if you experience allergic reactions, severe skin reactions, liver problems, or if you consume alcohol regularly. Always consult a healthcare professional if you have concerns or experience adverse effects.
Q: Is PYRIGESIC 1GM TABLET an antibiotic?
No. PYRIGESIC 1GM TABLET is an analgesic and antipyretic medicine. It works by reducing fever and provides pain relief.
Q: What happens if I take more doses of PYRIGESIC 1GM TABLET than recommended to me?
A: Taking more than the recommended doses of PYRIGESIC 1GM TABLET may be harmful. Studies have shown that the overdosage of paracetamol may affect your liver and gastrointestinal tract. Symptoms of overdosage might include vomiting, loss of appetite, stomach pain, paleness and nausea.
Q: Can PYRIGESIC 1GM TABLET be used for a headache?
A: Yes. PYRIGESIC 1GM TABLET can relieve your headache. It can also symptomatically manage headaches, however, cannot manage the underlying cause. If you experience recurrent headaches, please consult your doctor. In such cases, avoid self-medication with over-the-counter pain killers.
Q: Can PYRIGESIC 1GM TABLET be used during pregnancy?
A: PYRIGESIC 1GM TABLET can be used during pregnancy, however not during the last trimester as it could delay the onset of pain sensation. If necessary, you should use the lowest possible dose that reduces your pain and/or your fever and use it for the shortest time possible.
Q: What happens if I take Dolo 650 without fever?
A: Dolo 650 tablet is generally used for managing pain and fever, It can be used without getting a fever in most cases, especially if you have headaches, toothaches, or period cramps.
References
1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 693.
2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 206.
3. Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol and Enzo Nisoli. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 12th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/
4. Ohashi N and Kohno T. Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action. Pharmacology. Frontiers. November 2020. [Accessed on 12th August 2022] https://www.frontiersin.org/articles/10.3389/fphar.2020.580289/full
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 12th August 2022] https://www.medicines.org.uk/emc/files/pil.1958.pdf
6. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 12th August 2022] https://www.medicines.org.uk/emc/files/pil.4195.pdf
7. GlaxoSmithKline Asia Private Limited. Crocin 500 mg and Crocin 650 mg (Paracetamol). [Accessed on 12th August 2022] https://www.crocin.com/content/dam/cf-consumer-healthcare/panadol/en_in/adult/productshots/pdfs/Crocin-650-mg-Product-Info.pdf
Useful Diagnostic Tests
- Complete blood count
- Liver function test
Author Details
