Prostagard D 8mg Capsule 10'S

Introduction About PROSTAGARD D 8MG CAPSULE

Prostagard D 8mg Capsule is a widely used capsule in the urology segment. It contains specific ingredients chosen for their efficacy in supporting urinary health. It is a combination of Silodosin and Dutasteride formulated to provide effective relief from urinary symptoms caused by an enlarged prostate (Benign Prostatic Hyperplasia). It helps alleviate signs like frequent urination, especially at night (nocturia), a weak or interrupted urine flow, difficulty starting urination, and a feeling of incomplete bladder emptying.

Take the Prostagard D 8mg Capsule with water, preferably after meals, following your healthcare provider’s directions. Swallow whole and do not crush or chew. Always follow the dosage as advised by your healthcare professional.

Prostagard D 8mg Capsule is not suitable for women or children. Before taking Prostagard D 8mg Capsule, inform your doctor if you have low blood pressure, or liver or kidney conditions, as it may not be appropriate for you. Additionally, it can interact with other medications, so ensure your doctor is aware of all medicines you are taking.

Men taking Prostagard D 8mg Capsule should not donate blood for at least 6 months after their last dose, in order to manage the exposure of the medicine to pregnant women via blood transfusion. Avoid consumption of alcohol while taking Prostagard D 8mg Capsule, as it may lower your blood pressure.

The most common side effects of this medicine include reduced libido, difficulty achieving an erection (impotence), breast tenderness, and breast enlargement. Store in a cool and dry place away from sunlight. Keep out of reach of children and pets. Do not use beyond the expiry date mentioned on the pack.

Uses Of PROSTAGARD D 8MG CAPSULE

• Used to manage Urinary symptoms of benign prostatic hyperplasia  

Benefits of PROSTAGARD D 8MG CAPSULE

• Relieves difficulty in urination
• Improves urine flow and bladder control
• Reduces frequent nighttime urination (nocturia)
• Helps shrink the enlarged prostate gland over time

How PROSTAGARD D 8MG CAPSULE Works

PROSTAGARD D 8MG CAPSULE is a combination of two active ingredients, Silodosin and Dutasteride, that work together to manage the symptoms of an enlarged prostate (Benign Prostatic Hyperplasia or BPH).

• Silodosin: It is an alpha-blocker that relaxes the muscles in the prostate gland and bladder neck. By improving muscle relaxation, it helps enhance urine flow and reduces urinary symptoms such as frequent urination, difficulty starting urination, and incomplete bladder emptying.
• Dutasteride: It is a 5-alpha reductase inhibitor that reduces the production of dihydrotestosterone (DHT), a hormone responsible for prostate growth. Over time, this helps shrink the prostate gland, alleviating pressure on the bladder and urethra.

By combining these actions, Prostagard D 8mg Capsule effectively manages urinary symptoms of BPH, improving quality of life and reducing the risk of complications like urinary retention. For best results, it should be taken as prescribed by your doctor.

How to use PROSTAGARD D 8MG CAPSULE

• Take the Prostagard D 8mg Capsule with water, preferably after meals, following your healthcare provider’s directions
• Swallow whole and do not crush or chew
• Always follow the dosage as advised by your healthcare professional.

1. Dosage and Administration

• Initial Dosage: One dose per day, as directed by your physician
• Adjustments: Dosage adjustments should only be made under a doctor's supervision based on your condition and response to treatment
• Duration: Follow your healthcare provider’s recommendation for how long you should take Prostagard D 8mg Capsule

2. Missed Dosage Instructions for Prostagard D 8mg Capsule

• If you forgot a dose of Prostagard D 8mg Capsule, take it as soon as you remember, unless it is almost time for the next dose
• Do not take two doses at once to make up for a missed dose

3. Overdosage instructions  

• In case of an overdose, contact your doctor or seek emergency medical attention immediately
• Symptoms of overdose may include dizziness, fainting or abnormal heartbeats
• Management of overdose may involve supportive care depending on the severity of the symptoms

4. Misuse, Drug Abuse, and Dependence:

• Prostagard D 8mg Capsule is not intended for misuse or abuse. It is a prescription medication that should only be used as directed by your healthcare provider
• There is no known risk of physical dependence or addiction with Prostagard D 8mg Capsule, but misuse can lead to ineffective results or side effects.

Side Effects Of PROSTAGARD D 8MG CAPSULE

• reduced libido
• difficulty achieving an erection
• dizziness
• headache
• ejaculation problems
• fatigue

When to consult your doctor?

• Severe allergic reactions like rash, itching, or swelling of the face or throat
• breast enlargement or tenderness
• a rare but serious side effect that requires immediate medical attention if an erection lasts more than 4 hours

How To Manage Side Effects

Dizziness Or Drowsiness

• Avoid sudden movements, when standing up from a sitting or lying position, do so slowly to help manage dizziness caused by a drop in blood pressure
• Drink plenty of fluids throughout the day to help manage dehydration, which can worsen dizziness
• If you feel dizzy, sit or lie down in a comfortable position until the sensation passes. Avoid walking or performing any tasks that require balance when you are feeling dizzy

Warning & Precautions

Pregnancy

Contraindicated

Prostagard D 8mg Capsule is not recommended for use during pregnancy, particularly due to the presence of Dutasteride. Because it may harm a developing fetus, especially male fetuses, as it may affect the development of the male reproductive organs.

Breastfeeding

Contraindicated

It is not known whether Prostagard D 8mg Capsule passes into breast milk. Due to potential risk to the infant, this medicine is generally not recommended for use while breastfeeding. Always discuss with your healthcare provider before taking this medication if you are breastfeeding.

Driving and Using Machines

Use with Caution

Do not drive or handle any machines if you experience low blood pressure when standing up from sitting or lying position (with or without symptoms such as dizziness).

Alcohol

Contraindicated

Consumption of alcohol is not recommended while taking Prostagard D 8mg Capsule, as it may lower your blood pressure.

Kidney

Consult your doctor

Prostagard D 8mg Capsule is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with moderate kidney impairment. In such patients, treatment should be started at low doses and gradually increased with close medical monitoring.  

Liver

Consult your doctor

Prostagard D 8mg Capsule is not recommended for use in patients with severe liver impairment. It should be used with caution in patients with liver problems.  

Allergy

Contraindicated

Do not take Prostagard D 8mg Capsule if you are allergic (hypersensitive) to Silodosin or Dutasteride or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

Prostagard D 8mg Capsule is not recommended for use in children and adolescents (below 18 years of age) due to lack of safety and efficacy information.

Use In Geriatrics

Use with Caution

Prostagard D 8mg Capsule should be used with caution in elderly patients (aged 65 years or above).  

Other Warnings for PROSTAGARD D 8MG CAPSULE

Before taking Prostagard D 8mg Capsule, inform your physician if you:

• have low blood pressure
• planned for cataract surgery or other procedures  

Safety Advice

Expert Advice to Maximize the Effects of Prostagard D 8mg Capsule

• Follow Your Doctor’s Instructions: Take Prostagard D 8mg Capsule exactly as prescribed. Do not change your dose or stop the medication without consulting your doctor, even if you feel better, to ensure consistent results and prevent symptom recurrence.
• Establish a Routine: Take the medicine at the same time every day to maintain consistency. Skipping doses can reduce effectiveness and delay symptom improvement.
• Take with a Light Meal: For better absorption, take Prostagard D 8mg Capsule with a light meal. Avoid high-fat meals as they may increase drug levels and the risk of side effects.
• Monitor Blood Pressure: Silodosin may cause dizziness or low blood pressure, especially at the start of treatment. Regularly check your blood pressure, particularly if you take antihypertensive medications. Consult your doctor if you feel faint or dizzy.
• Stay Hydrated: Drink plenty of water to help manage urinary discomfort and manage BPH symptoms.
• Limit Alcohol: Alcohol can increase the risk of side effects like dizziness and drowsiness when combined with Prostagard D 8mg Capsule. Limit or avoid alcohol during treatment.
• Avoid Grapefruit: Grapefruit and its juice can interfere with the medication's metabolism, increasing the risk of side effects. Avoid grapefruit while taking Prostagard D 8mg Capsule
• Regular Check-ups: Keep regular appointments with your doctor to track progress and adjust treatment as needed. It may take several weeks to see significant symptom relief.
• Inform Your Doctor About Other Medications: Always inform your doctors about any other medications, including over-the-counter drugs and supplements, to avoid drug interactions that may affect the effectiveness or increase the risk of side effects.

Diet and Lifestyle Advice

Lifestyle Changes to Complement Prostagard D 8mg Capsule for BPH:

• Stay Active: Engage in regular physical activity, such as walking or swimming, to improve urinary function and overall health
• Maintain a Healthy Weight: Losing excess weight can reduce pressure on the prostate and improve urinary symptoms
• Limit Caffeine and Alcohol: These can irritate the bladder and worsen urinary symptoms. Consider reducing or eliminating them from your diet
• Practice Bladder Training: Try to extend the time between urinations gradually to improve bladder control
• Stay Hydrated: Drink plenty of water throughout the day, but reduce fluid intake before bed to avoid frequent nighttime urination (nocturia)
• Manage Stress: Practice relaxation techniques such as deep breathing, meditation, or yoga to reduce stress, which can negatively impact urinary health
• Avoid Heavy Lifting: Straining can worsen BPH symptoms. Practice good posture and avoid heavy lifting that can put pressure on the pelvic area
• Eat a Balanced Diet: A diet rich in fruits, vegetables, and healthy fats can support prostate health and overall well-being
• Quit Smoking: Smoking can worsen urinary symptoms and impact circulation. Quitting may improve overall health and symptoms of BPH

Drug - Drug interaction

A. Drug-Drug interactions

1. Alpha-blockers: e.g., Tamsulosin
2. CYP3A4 Inhibitors: Drugs such as Ketoconazole, Itraconazole, and certain antifungal medications
3. CYP3A4 Inducers: Drugs like Rifampin, Carbamazepine, and certain anticonvulsants
4. Prostate Cancer Medications: Finasteride
5. Antihypertensives: e.g., ACE inhibitors, Beta-blockers

Drug - Food interaction

B. Drug-Food Interactions

1. Grapefruit: Grapefruit and grapefruit juice can affect the metabolism of Silodosin, increasing its levels in the bloodstream. This can heighten the risk of side effects like dizziness, fatigue, and hypotension. It is best to avoid grapefruit products while taking Prostagard D 8mg Capsule
2. Fatty Foods: Consuming high-fat meals with Prostagard D 8mg Capsule may increase the absorption of Silodosin, leading to higher levels of the drug in the body and a greater likelihood of side effects. It is advisable to take this medication with a light meal

Synopsis

More Information

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FAQs About PROSTAGARD D 8MG CAPSULE

Q: What is Prostagard D 8mg Capsule used for?

A: Prostagard D 8mg Capsule is primarily used for managing benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate. It combines silodosin (an alpha-blocker) and Dutasteride (a 5-alpha reductase inhibitor) to reduce prostate size and improve urinary flow, alleviating BPH symptoms like frequent urination and difficulty in urination.

Q: What are Prostagard D 8mg Capsule benefits for prostate enlargement?

A: Prostagard D 8mg Capsule helps reduce the size of an enlarged prostate, improving urinary symptoms associated with benign prostatic hyperplasia (BPH). It works by relaxing the muscles around the prostate and bladder and inhibiting the hormone responsible for prostate growth. This results in better urine flow, reduced urgency, and fewer nighttime bathroom visits.

Q: How does Prostagard D 8mg Capsule work for BPH?

A: Prostagard D 8mg Capsule works by combining two active ingredients: Dutasteride and Silodosin. Silodosin relaxes the muscles in the prostate and bladder, making it easier to urinate, while Dutasteride inhibits the enzyme that converts testosterone into dihydrotestosterone, the hormone responsible for prostate growth. Together, these actions relieve BPH symptoms and reduce the size of the prostate.

Q: What are the common side effects of Prostagard D 8mg Capsule?

A: Common side effects of Prostagard D 8mg Capsule include dizziness, especially when standing up quickly, fatigue, headaches, decreased libido, and sexual side effects like difficulty with ejaculation. Some men may also experience breast tenderness or enlargement due to Dutasteride.

Q: Can Prostagard D 8mg Capsule cause sexual side effects and libido?

A: Prostagard D 8mg Capsule may cause sexual side effects, including a reduction in libido (sexual desire) and changes in ejaculation, such as reduced semen volume. These side effects are primarily associated with Dutasteride, but they tend to improve over time or upon discontinuation of the medication.

Q: What happens if you forgot a dose of Prostagard D 8mg Capsule?

A: If you forget a dose of Prostagard D 8mg Capsule, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose, as this can increase the risk of side effects.

Q: Can Prostagard D 8mg Capsule be used for long-term?

A: Prostagard D 8mg Capsule is generally considered safe for long-term use, especially for managing benign prostatic hyperplasia (BPH). However, it is important to have regular check-ups with your healthcare provider to monitor your response to the medication and adjust the dosage if necessary.

Q: Is Prostagard D 8mg Capsule safe for elderly patients?

A: Prostagard D 8mg Capsule can be used by elderly patients, but they may be more sensitive to the effects of the medication, particularly dizziness or fatigue. It is essential for older patients to start with the lowest effective dose and regularly monitor for any side effects. Always consult with a healthcare provider for appropriate adjustments.

Q: Prostagard D 8mg Capsule vs Finasteride: Which is better for BPH?

A: Both Prostagard D 8mg Capsule and Finasteride are used for managing BPH, but Prostagard D 8mg Capsule combines two medications: silodosin (for muscle relaxation) and Dutasteride (for inhibiting prostate growth). Finasteride is a single-drug therapy that also targets DHT.  Prostagard D 8mg Capsule may provide faster symptom relief by combining both mechanisms. Your healthcare provider can recommend the best treatment based on individual needs.

Q: Can I buy Prostagard D 8mg Capsule online?

A: Yes, simply upload your prescription during checkout to comply with pharmacy requirements.

Q: How is my Prostagard D 8mg Capsule order delivered?

A: Your order is delivered in discreet, secure, and tamper-proof packaging to maintain privacy.

Q: Who can guide me about the right usage?

A: For any queries, consult your healthcare provider or our licensed pharmacist through live chat.

References

1. KD. Tripathi. Antiadrenergic Drugs and Drugs for Glaucoma & Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 142-144 & 303
2. Iram Kahkashan, Shabnam Chawdhary, Vishal R. Tandon, Rahul Gupta. To compare the efficacy and safety of silodosin and dutasteride combination with alfuzosin and dutasteride combination in patients of benign prostatic hyperplasia: a randomized, open label study. International journal of basic & clinical pharmacology (IJBCP). 2019. [Accessed on July 18, 2025] 
3. Cipla House. Swiss Garnier Genexiaa Sciences Pvt. Ltd. [Revised in February 2021] [Accessed on July 18, 2025] 
4. APL Swift Services (Malta) Limited or Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in August 2019] [Accessed on July 18, 2025] 
5. Recordati S.p.A. European Medicines Agency (EMA). [Accessed on July 18, 2025] 

Useful Diagnostic Tests

• Prostate Specific Antigen (PSA) – Free

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 24 Jul 2025 | 09:28 AM(IST)