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Introduction About PROPYGENTA NF CREAM
PROPYGENTA NF CREAM is a combination of Clobetasol and Neomycin which belongs to the group of medicines called Corticosteroids and Antibiotics. It is used to manage resistant dermatoses (skin infections) with secondary fungal infections. Ex. psoriasis (except widespread plaque psoriasis) and recalcitrant dermatoses.
PROPYGENTA NF CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation, perianal and genital pruritus, and perforated ear drum. Contact your doctor before applying.
PROPYGENTA NF CREAM should be used with caution in patients with kidney disease, psoriasis. Contact your doctor before applying.
PROPYGENTA NF CREAM is generally not recommended for use in pregnancy. Contact your doctor before applying. PROPYGENTA NF CREAM is generally not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.
PROPYGENTA NF CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.
PROPYGENTA NF CREAM should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before applying.
The most common side effects of this medicine are pruritus, skin burning or skin pain. Contact your physician if any of the symptoms worsen.
Uses Of PROPYGENTA NF CREAM
It is used to manage:
- resistant dermatoses (skin infections) with secondary fungal infection Ex. psoriasis (except widespread plaque psoriasis)
- recalcitrant dermatoses
How PROPYGENTA NF CREAM Works
PROPYGENTA NF CREAM helps to manage infection, where Clobetasol belongs to corticosteroids which blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Neomycin is an antibiotic which stops the growth of bacteria in the skin. Together, manages skin infection effectively.
How to use PROPYGENTA NF CREAM
Apply PROPYGENTA NF CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes.
Side Effects Of PROPYGENTA NF CREAM
Common
- pruritus, skin burning or skin pain
Warning & Precautions
Pregnancy
ContraindicatedPROPYGENTA NF CREAM is not recommended for use in pregnancy. Contact your doctor before applying.
Breastfeeding
ContraindicatedPROPYGENTA NF CREAM is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.
Kidney
Use with CautionPROPYGENTA NF CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.
Allergy
ContraindicatedDo not use PROPYGENTA NF CREAM if you are allergic to Clobetasol or Neomycin or to any other ingredients of this medicine.
Others
PROPYGENTA NF CREAM is not recommended for use if you have:
- rosacea
- acne vulgaris
- perioral dermatitis
- pruritus without inflammation
- perianal and genital pruritus
- primary cutaneous viral infections
- primary infected skin lesions caused by bacterial, fungal or yeast infections
- secondary infections (due to pseudomonas or proteus species)
- otitis externa where the eardrum is perforated
Before applying PROPYGENTA NF CREAM, inform your doctor if you have:
- psoriasis
Use in Pediatrics:
PROPYGENTA NF CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.
Use in geriatrics:
PROPYGENTA NF CREAM should be used with caution in elderly patients. The greater frequency of decreased hepatic or renal function in the elderly may delay elimination if systemic absorption occurs. Contact your doctor before applying.
Interactions
A. Drug-Drug interactions:
Tell your doctor before using PROPYGENTA NF CREAM if you are taking the following medicines:
- ritonavir (medicines used for HIV infections)
- itraconazole (medicines used for fungal infections)
- aminoglycosides like amikacin, gentamicin (medicines used for bacterial infections)
- neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)
Overdosage:
If you or anyone else accidentally uses too much of PROPYGENTA NF CREAM, consult your doctor immediately or visit the nearby hospital. Acute overdosage is very unlikely, however, in the case of chronic overdosage or misuse, hypercortisolism-like symptoms may occur.
Synopsis
| Drug | : | Clobetasol, Neomycin |
| Pharmacological Category | : | Corticosteroids, Antibiotics |
| Therapeutic Indication | : | Skin infections |
| Dosage Forms | : | Cream |
More Information
- Keep out of reach of children
- Store PROPYGENTA NF CREAM below 25°C
FAQs About PROPYGENTA NF CREAM
Q: What are the possible side effects of applying PROPYGENTA NF CREAM?
A: The most common side effects of this medicine are pruritis, skin burning sensation or skin pain. Contact your physician if any of the symptoms worsen.
Q: How PROPYGENTA NF CREAM works?
A: PROPYGENTA NF CREAM helps to manage infection where Clobetasol is a corticosteroid which blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Neomycin is an antibiotic which stops the growth of bacteria in the skin. Together, manages skin infection effectively.
Q: For what conditions PROPYGENTA NF CREAM is used?
A: PROPYGENTA NF CREAM is used to manage resistant dermatoses (skin infections) with secondary fungal infections, Ex. psoriasis (except widespread plaque psoriasis) and recalcitrant dermatoses. Contact your doctor before applying.
Q: Can I stop using PROPYGENTA NF CREAM when my symptoms are relieved?
A: No, do not stop using PROPYGENTA NF CREAM and complete the full course of management even if you feel better. Your symptoms may improve before the infection is completely managed.
Q: How long do the effects of this PROPYGENTA NF CREAM last?
A: The amount of time for which PROPYGENTA NF CREAM remains active in your body is not clinically established.
Q: Who should not apply PROPYGENTA NF CREAM?
A: PROPYGENTA NF CREAM is not recommended for use in patients with pregnancy, breast feeding women, children under 2 years of age, rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation, perianal and genital pruritus, and perforated ear drum. Contact your doctor before applying.
References
1. K.D. Tripathi. Corticosteroids, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 289, 792, 750.
2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051
3. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin
4. GlaxoSmithKline Pharmaceuticals Limited. Clobetasol propionate and neomycin. [Revised in July 2020] [Accessed on 24th June 2022] https://india-pharma.gsk.com/media/6415/tenovate-gn.pdf
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