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Introduction About PROPEROL 1MG INJECTION
PROPEROL 1MG INJECTION contains Propranolol which belongs to the group of medicines called Beta blockers. It is used to manage certain forms of life-threatening arrhythmias (such as supraventricular arrhythmias, ventricular tachycardias, tachyarrhythmias of digitalis intoxication or Resistant tachyarrhythmias). It can also be used to control abnormal increase in blood pressure and/or heart rate caused due to phaeochromocytoma (tumours of adrenal gland).
Arrhythmia can be defined as an irregular heartbeat caused due to abnormal electrical signals in the heart. Symptoms of arrhythmia includes palpitations (racing heartbeat), weakness, fatigue, dizziness and chest pain.
Before receiving PROPEROL 1MG INJECTION inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, any skin allergies or thyroid problems as a precaution.
PROPEROL 1MG INJECTION is not recommended for use in patients with severe asthma, hypotension (low blood pressure) or shock. It is also not suitable for use in patients with heart block, history of heart attack or heart failure.
Inform your doctor before receiving PROPEROL 1MG INJECTION if you are pregnant or breastfeeding. The most common side effects of receiving PROPEROL 1MG INJECTION are nausea, vomiting, stomach pain, diarrhea, cold fingers and toes, tiredness, sleep disturbances and Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain). Consult your doctor if any of these side effect troubles you.
Uses Of PROPEROL 1MG INJECTION
It is used to manage:
- certain forms of life-threatening cardiac arrhythmias
- Pheochromocytoma (tumours of adrenal gland)
How PROPEROL 1MG INJECTION Works
PROPEROL 1MG INJECTION is a beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline) in our body that controls the function of the heart, brain and kidneys and lungs.
In the heart, stopping the actions of these chemical messengers reduces the heart rate and force of contraction. This helps to control abnormal heart rate in patients suffering from arrhythmia.
It can also reduce the risk of abnormal heart signs (such as racing heartbeat, nervousness and high blood pressure) associated with phaeochromocytoma.
How to use PROPEROL 1MG INJECTION
PROPEROL 1MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects Of PROPEROL 1MG INJECTION
Common
- dry eyes and visual disturbances
- nausea and vomiting
- diarrhoea, loss of appetite, stomach pain
- fingers and toes may become cold
- signs of Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain)
- sleep disturbances, nightmares
Uncommon
- ringing in the ears
- hypoglycaemia (low blood sugar causing excess sweating, hunger, fatigue, light-headedness or shakiness)
Rare
- hair loss
- low sex drive
- dizziness while standing up
Contact your doctor immediately if you experience any of the following side effects after receiving PROPEROL 1MG INJECTION:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
- signs of congestive heart failure (difficulty breathing and swollen ankles)
- signs of bronchospasm (chest tightness, shortness of breath, wheezing, coughing, tiredness and dizziness)
How To Manage Side Effects
Nausea and vomiting:
Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Sleep disturbance:
Practicing good sleep practices such as having a regular bedtime schedule, avoiding naps in the daytime, limiting caffeine and TV before bedtime can help you to sleep peacefully. If the symptom does not improve, consult your doctor.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Warning & Precautions
Pregnancy
PROPEROL 1MG INJECTION is generally not recommended for use in pregnant women unless considered necessary by the physician, as it may harm the growing baby. Therefore, inform your doctor before receiving PROPEROL 1MG INJECTION if you are pregnant, think you might be pregnant or planning to have a baby.
Breastfeeding
PROPEROL 1MG INJECTION may excrete in breast milk. Therefore, it should be used with caution in breastfeeding women. Consult your doctor for advice before receiving it.
Driving and Using Machines
PROPEROL 1MG INJECTION is unlikely to affect your ability for driving or handling any heavy tools or machines. However, if your experience any dizziness or drowsiness, do not drive or handle any heavy tools or machines as a precaution.
Alcohol
Avoid consumption of alcohol before receiving PROPEROL 1MG INJECTION as it might make you feel dizzier and drowsier.
Kidney
PROPEROL 1MG INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
Liver
PROPEROL 1MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.
Allergy
Talk to your doctor before receiving PROPEROL 1MG INJECTION if you are allergic to propranolol.
Lungs
PROPEROL 1MG INJECTION is not recommended for use in patients suffering from asthma or high blood pressure in the lungs. It should be used with caution in patients with other respiratory problems (such as chronic bronchitis, emphysema, COPD or bronchospasm). Therefore, consult your doctor before receiving it.
Heart Disease
PROPEROL 1MG INJECTION is not recommended for use in patients with sinus bradycardia (slow heart beat due to problems in SA nodes), heart block, congestive heart failure or heart defects. It should be used with caution in patients with a previous history of heart failure or other heart problems. Therefore, consult your doctor before receiving it.
Others
PROPEROL 1MG INJECTION is not recommended for use if you:
- have cardiogenic shock (heart cannot pump blood suddenly)
- have very low blood pressure
- have allergic rhinitis
- have can increased acidity of the blood (metabolic acidosis)
- have poor blood circulation
- have unmanageed pheochromocytoma
Before receiving PROPEROL 1MG INJECTION, inform your doctor if you:
- have history of skin allergies
- have diabetes
- have overactive thyroid gland
- are going for glaucoma screening test
- are planning for any major surgery
Use in Pediatrics:
The safety and effectiveness of PROPEROL 1MG INJECTION have not been established in children and adolescents (aged below 18 years). Therefore, it should be used in children only if prescribed by the physician.
Use in geriatrics:
PROPEROL 1MG INJECTION should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before receiving it.
Interactions
A. Drug - Drug interactions:
Before receiving PROPEROL 1MG INJECTION, inform your doctor if you are taking any of the following medicine such as:
- other medicines used in the management of hypertension and other heart problems (Ex. nifedipine, nisoldipine, nicardipine, isradipine, lacidipine, verapamil, diltiazem, hydralazine, clonidine, enalapril, lisinopril, ramipril, disopyramide, quinidine, amiodarone, isoprenaline, dobutamine, propafenone and digoxin)
- alpha blockers (used to manage hypertension and BPH) Ex. prazosin, doxazosin
- reserpine (an antihypertensive from plant source)
- adrenaline (a medicine that can stimulate the heart)
- medicines used to manage migraine headaches (Ex. ergotamine, dihydroergotamine or rizatriptan)
- benzodiazepines (used to reduce anxiety and to induce sleep) Ex. alprazolam, midazolam, diazepam, clonazepam
- insulin (a medicine used to manage diabetes)
- cimetidine (a medicine used to manage stomach ulcers)
- ibuprofen and indomethacin (medicine used to relieve pain and inflammation)
- medicine used in the management of mental illness (Ex. chlorpromazine, thioridazine, haloperidol)
- theophylline (a medicine used to manage asthma)
- warfarin (a medicine that manages blood clot formation)
- medicines used to manage depression (Ex. isocarboxazid, phenelzine, Selegiline, fluvoxamine and Tranylcypromine)
- methoxyflurane and trichloroethylene (used as anaesthetic agents)
- thyroxine (a medicine used to manage thyroid deficiency)
Overdosage:
PROPEROL 1MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any slow heartbeat, low blood pressure and signs of bronchospasm (chest tightness, shortness of breath, wheezing, coughing, tiredness and dizziness).
Synopsis
| Drug | : | Propranolol |
| Pharmacological Category | : | Beta blockers |
| Therapeutic Indication | : | Cardiac arrhythmias, Pheochromocytoma |
| Dosage Forms | : | Tablet, Capsule, Injection |
More Information
- Keep PROPEROL 1MG INJECTION out of reach of children
- Store PROPEROL 1MG INJECTION at room temperature
FAQs About PROPEROL 1MG INJECTION
What should be monitored when taking PROPEROL 1MG INJECTION?
While you are receiving PROPEROL 1MG INJECTION, you will need to monitor your blood pressure, heart rate and blood sugar levels, especially if you have diabetes because this medicine tends to slow down your heart rate, lower blood pressure and blood sugar level. If you notice any of these things, please contact your doctor immediately.
Can PROPEROL 1MG INJECTION used in asthmatic patients?
No, PROPEROL 1MG INJECTION cannot be used in patients suffering from asthma. This is because using it can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any kind of difficulty breathing difficulty, before starting management with PROPEROL 1MG INJECTION.
Does PROPEROL 1MG INJECTION make you feel sleepy?
PROPEROL 1MG INJECTION may occasionally cause dizziness or tiredness while taking it. Don't drive, use machinery or perform any activities that require alertness. If this occurs to you, consult your doctor for opinion.
When can I expect relief in my symptoms after taking PROPEROL 1MG INJECTION?
PROPEROL 1MG INJECTION usually starts working within a few hours of taking it. However, to notice considerable changes in the symptoms of high blood pressure or heart conditions, it may take a week. You will not be able to notice any difference, but that does not mean it is not working. However, keep taking PROPEROL 1MG INJECTION as prescribed by your doctor to get its full benefits.
What are the uses of PROPEROL 1MG INJECTION?
PROPEROL 1MG INJECTION It is used to manage certain forms of life-threatening arrhythmias. It can also be used to manage signs and symptoms associated with phaeochromocytoma.
What type of a medicine is PROPEROL 1MG INJECTION?
PROPEROL 1MG INJECTION is a beta-blocker. It works by blocking the actions of certain chemical messengers (such as adrenaline and noradrenaline). This helps to control abnormal heart rate in patients suffering from arrhythmia. It can also reduce the risk of abnormal heart signs (such as racing heartbeat, nervousness and high blood pressure) associated with phaeochromocytoma.
Can PROPEROL 1MG INJECTION reduce anxiety?
PROPEROL 1MG INJECTION may control racing heartbeat and nervousness associated with anxiety. However, consult your doctor before receiving it.
What precautions should be followed while taking PROPEROL 1MG INJECTION?
Before receiving PROPEROL 1MG INJECTION inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, asthma, skin allergies, thyroid problems, heart failure as a precaution. Inform your doctor before receiving PROPEROL 1MG INJECTION if you are pregnant or breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
Can I consume alcohol while receiving PROPEROL 1MG INJECTION?
Avoid consumption of alcohol before receiving PROPEROL 1MG INJECTION as it might make you feel dizzier and drowsier.
Is PROPEROL 1MG INJECTION safe to use in diabetic patients?
PROPEROL 1MG INJECTION may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before receiving PROPEROL 1MG INJECTION as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
What are the side effects of PROPEROL 1MG INJECTION?
The most common side effects of receiving PROPEROL 1MG INJECTION are nausea, vomiting, stomach pain, diarrhea, cold fingers and toes, tiredness, sleep disturbances and Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain). Consult your doctor if any of these side effect troubles you.
Can I stop management with PROPEROL 1MG INJECTION once my symptoms subside?
No. Do not stop therapy with PROPEROL 1MG INJECTION without consulting your doctor as it may make your symptoms reappear.
Can PROPEROL 1MG INJECTION be taken during pregnancy?
PROPEROL 1MG INJECTION is generally not recommended for use in pregnant women unless considered necessary by the physician, as it may harm the growing baby. Therefore, inform your doctor before receiving PROPEROL 1MG INJECTION if you are pregnant, think you might be pregnant or planning to have a baby.
Is PROPEROL 1MG INJECTION safe to use in kidney disease?
PROPEROL 1MG INJECTION should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Can the use of PROPEROL 1MG INJECTION affect the liver?
Yes. PROPEROL 1MG INJECTION may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before receiving it.
References
1. KD. Tripathi. Adrenergic drugs and drugs acting on glaucoma. Essentials of medical pharmacology. 7th Edition. 2019. Page – 145-151.
2. Mahsa Shahrokhi; Vikas Gupta. Propranolol. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. May 2022. [Accessed on 5th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK557801/
3. Hikma Pharmaceuticals USA Inc. Propranolol Hydrochloride Injection. Dailymed.com. [Revised in May 2022]. [Accessed on 5th November 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91f2ff1d-68d8-4e83-a2db-618f0410ead7#:~:text=Intravenous%20propranolol%20is%20indicated%20for,not%20respond%20to%20conventional%20measures.&text=Intravenous%20propranolol%20is%20indicated%20to,%2Dthreatening%20digitalis%2Dinduced%20arrhythmias.
4. Sandoz Canada Inc. PROPRANOLOL HYDROCHLORIDE INJECTION USP (Propranolol Hydrochloride). [Revised in June 2013]. [Accessed on 5th November 2022] https://www.sandoz.ca/sites/www.sandoz.ca/files/Propranolol%20HCl%20PMe%20%2020130619.pdf
Useful Diagnostic Tests
- Kidney Function Test
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