Proanes 10mg Infusion 50ml

Introduction About PROANES 10MG INFUSION

PROANES 10MG INFUSION contains Propofol which belongs to the group of medicines called General Anaesthetic agents. It is used to cause partial or complete loss of consciousness in patients so that surgical procedures can be performed. Unconsciousness caused by propofol is completely reversed once the effect of the medicine wears off. It can also be used to induce sleep in patients receiving artificial respiration in an Intensive Care Unit (ICU).

PROANES 10MG INFUSION will be given to you only by a doctor or by a trained anesthesiologist into the vein (intravenously). It is suitable for use both in adults and in children (aged 1 month or older). It is mostly used in combination with other local anaesthetics to achieve faster results.

Before receiving PROANES 10MG INFUSION inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have fits, high blood cholesterol levels or dehydration as a precaution.

PROANES 10MG INFUSION is not recommended for use in pregnant women unless considered necessary by the physician. Breastfeeding should be stopped for 24 hours or until the effect of the medicine completely wears off, as this medicine may pass to the nursing infant through the breast milk.

The most common side effects of receiving PROANES 10MG INFUSION are pain, swelling and redness at the site of injection, low blood pressure, slow heartbeat, nausea, vomiting, headache and flushing. Consult your doctor if any of these side effect worsens.

Uses Of PROANES 10MG INFUSION

• Used to cause partial or complete loss of consciousness prior to surgical procedures
• Induces sleep in patients receiving artificial respiration in an Intensive Care Unit (ICU)

How PROANES 10MG INFUSION Works

PROANES 10MG INFUSION is a general anaesthetic agent. It produces loss of consciousness by potentiating the actions of certain brain chemicals (GABA) any by decreasing the flow of certain ions (chloride) across the nerve cells that is required to maintain alertness.

How to use PROANES 10MG INFUSION

PROANES 10MG INFUSION will be given to you only by a doctor or by a trained anesthesiologist into the vein (intravenously).

Your doctor/ anesthesiologist will decide the correct dose for you depending upon the age, body weight and disease condition.

Side Effects Of PROANES 10MG INFUSION

How To Manage Side Effects

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.

Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.

Warning & Precautions

Pregnancy

Contraindicated

PROANES 10MG INFUSION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before receiving it.

Breastfeeding

Contraindicated

Breastfeeding should be stopped for 24 hours or until the effect of the medicine completely wears off, as this medicine may pass to the nursing infant through the breast milk.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines until the effects of the medicine complete wears off

Alcohol

Consult your doctor

Avoid consumption of alcohol before receiving PROANES 10MG INFUSION.

Kidney

Use with Caution

PROANES 10MG INFUSION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.

Liver

Use with Caution

PROANES 10MG INFUSION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.

Allergy

Contraindicated

Inform your doctor before receiving PROANES 10MG INFUSION, if you are allergic to Propofol.

Lungs

Use with Caution

PROANES 10MG INFUSION should be used with caution in patients with breathing disorders (such as asthma or COPD). Therefore, consult your doctor before receiving it.

Heart Disease

Use with Caution

PROANES 10MG INFUSION should be used with caution in patients with heart disorders. Therefore, consult your doctor before receiving it.

Interactions

A. Drug-Drug interactions:

Before receiving PROANES 10MG INFUSION, inform your doctor if you are receiving any of the following medicines:

• Rifampicin (a medicine used to manage tuberculosis)

Overdosage:

PROANES 10MG INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

• Keep PROANES 10MG INFUSION out of reach of children
• Store PROANES 10MG INFUSION at room temperature

FAQs About PROANES 10MG INFUSION

Q: What is the use of PROANES 10MG INFUSION?

A: PROANES 10MG INFUSION is used to cause partial or complete loss of consciousness in patients so that surgical procedures can be performed. It can also be used to induce sleep in patients receiving artificial respiration in an Intensive Care Unit (ICU).

Q: How long will it take for the effects of PROANES 10MG INFUSION to wear off?

A: The effect of PROANES 10MG INFUSION may wear off after 24 hours. However, this period may vary from person-to-person based on the dose administered.

Q: Can PROANES 10MG INFUSION be used in children?

A: PROANES 10MG INFUSION should be used in children and adolescents (aged below 18 years) only if it is considered necessary by the physician. It is not recommended for use in neonates aged less than 1 month. Therefore, consult your doctor for advice before administration.

Q: What are the side effects of receiving PROANES 10MG INFUSION?

A: The most common side effects of receiving PROANES 10MG INFUSION are pain, swelling and redness at the site of injection, low blood pressure, slow heartbeat, nausea, vomiting, headache and flushing. Consult your doctor if any of these side effect worsens.

Q: Can PROANES 10MG INFUSION be used during pregnancy?

A: PROANES 10MG INFUSION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before receiving it.

References

1. KD. Tripathi. General anesthetics. Essentials of medical pharmacology. 7th Edition. 2013. Page – 382.

2. Thomas B. Folino; Erind Muco; Anthony O. Safadi; Lance J. Parks. Propofol. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed central. July 2022. [Accessed on 3rd January 2023] https://www.ncbi.nlm.nih.gov/books/NBK430884/

3. Aspen Pharma Trading Limited. Propofol 10mg/ml (1%) emulsion for injection or infusion propofol. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 3rd January 2023] https://www.medicines.org.uk/emc/files/pil.5492.pdf

4. Baxter Healthcare Limited. Propofol 20 mg/ml Emulsion for injection/infusion. Electronic Medicines Compendium (EMC). [Revised in June 2022] [Accessed on 3rd January 2023] https://www.medicines.org.uk/emc/product/11294/smpc#gref

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Abdul Rahman Danish - MBBS, MD (Anesthesia)

Last updated on 04 Feb 2023 | 05:18 PM(IST)