PRIDILAN 40 SR Tablet 10's
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Introduction About PRIDILAN 40 TABLET
PRIDILAN 40 TABLET contains Isoxsuprine which belongs to the group of medicines called Vasodilators. It is used in the management of premature labor (when the uterus starts contracting for birth too early than usual), cerebral vascular insufficiency (poor blood flow to the brain) and arteriosclerosis obliterans (hardening of the arteries).
PRIDILAN 40 TABLET can also be used to manage Buerger's disease (blood vessels become inflamed, swollen and can become blocked with blood clots), Raynaud’s phenomenon (decreased blood flow to the nose, ears, fingers, toes, nipples or knees) and dysmenorrhea (painful menstrual cramps).
PRIDILAN 40 TABLET should not be used immediately after delivering a baby or if you have a bleeding disorder. PRIDILAN 40 TABLET is not recommended for use if you have any heart disease (especially arrhythmias), hyperthyroidism, chorioamnionitis, bleeding, eclampsia or pre-eclampsia.
Avoid smoking and consuming alcohol while taking PRIDILAN 40 TABLET as it may cause dizziness. Do not take PRIDILAN 40 TABLET if you are pregnant or breastfeeding without consulting your doctor. Safety and effectiveness of PRIDILAN 40 TABLET in children have not been established.
Your doctor may want you to take blood tests or other medical evaluations during management with PRIDILAN 40 TABLET to monitor progress and side effects. The most common side effects of taking PRIDILAN 40 TABLET are chest pain or an irregular heartbeat, nausea, vomiting, dizziness or weakness. Contact your physician if any of the symptoms deteriorate.
Uses Of PRIDILAN 40 TABLET
Manage:
- premature labor
- cerebral vascular insufficiency
- arteriosclerosis obliterans
- thromboangitis obliterans (Buerger's disease)
- Raynaud’s phenomenon
- dysmeorrhea
How PRIDILAN 40 TABLET Works
PRIDILAN 40 TABLET manages premature labor by managing the contractions of the smooth muscles in the uterus. In peripheral vascular disease, it helps in widening of blood vessels to increase blood flow, thereby improving blood circulation to certain parts of the body (such as the hands/feet and brain).
How to use PRIDILAN 40 TABLET
Take PRIDILAN 40 TABLET as advised by your physician. Swallow the medicines with enough water. Do not crush or chew it. The correct dose and duration will be decided by your physician for you according to your age, body weight and disease condition.
Side Effects Of PRIDILAN 40 TABLET
Common
- chest pain
- nausea, vomiting, upset stomach
- dizziness, weakness
- shaking
- fast heartbeat
- low blood pressure
- excessive fluid in the lungs
Rare
- chest pain
- shortness of breath
Stop taking PRIDILAN 40 TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (symptoms like difficulty breathing, closing of the throat, swelling of the lips, tongue or face, hives)
- rash
- restarting of contractions or breaking of water
How To Manage Side Effects
Nausea or vomiting:
Take PRIDILAN 40 TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Dizziness:
Lie or sit down promptly when you feel dizzy. If you're feeling severe episode of spinning, lie in a dark and quite place and close your eyes. Try to avoid vehicle driving. If symptom persists, contact your doctor.
Skin rash:
Avoid hot showers as it can irritate your skin more. Do not scratch the affected area. Use protective clothing when going outdoors and moisturize your skin regularly. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
PRIDILAN 40 TABLET is not recommended for use in pregnant women unless considered clearly necessary as it is not known whether this medicine will be harmful to an unborn baby. Consult your doctor before taking it.
Breastfeeding
PRIDILAN 40 TABLET is not recommended for use in breastfeeding women unless considered clearly necessary as it is not known whether this medicine passes into breast milk. Consult your doctor before taking it.
Driving and Using Machines
Do not drive, use any machines or do anything that needs attention if you feel sleepy or dizzy after taking PRIDILAN 40 TABLET.
Allergy
Do not take PRIDILAN 40 TABLET if you are allergic to Isoxsuprine, lactose or some sugars or to any of the other ingredients of this medicine.
Heart Disease
PRIDILAN 40 TABLET is not recommended for use in patients having heart diseases, especially arrhythmias (irregular heartbeat). Consult your physician before taking it.
Others
PRIDILAN 40 TABLET is not recommended for use if you:
- have hyperthyroidism (overactive thyroid)
- have chorioamnionitis (infection of the amniotic fluid and tissue around the baby during pregnancy)
- have bleeding problems
- have eclampsia or preeclampsia (high blood pressure problems during pregnancy)
- just had a baby (immediately postpartum)
Before taking PRIDILAN 40 TABLET, inform your doctor if you:
- smoke tobacco
- have glaucoma (increased eye pressure)
Use in pediatrics:
Safety and effectiveness of PRIDILAN 40 TABLET in children have not been established. Consult your child’s doctor for advice.
Use in geriatrics:
No specific information is available on the use of PRIDILAN 40 TABLET in elderly patients. It may reduce tolerance to cold temperatures in these patients. Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking PRIDILAN 40 TABLET, inform your doctor if you are taking any of the following medicines:
- other medicines used to manage low blood pressure (Ex. cilnidipine, phenylephrine)
- other vasodilators (Ex. hydralazine, minoxidil)
Overdosage:
If you or anyone else accidentally take too much of PRIDILAN 40 TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage may include weakness, lightheadedness, fainting, nausea and vomiting.
Synopsis
| Drug | : | Isoxsuprine |
| Pharmacological Category | : | Vasodilators |
| Therapeutic Indication | : | Premature labor, to improve blood flow |
| Dosage Forms | : | Tablet, Capsule, Injection |
More Information
- Keep PRIDILAN 40 TABLET out of reach of children
- Store PRIDILAN 40 TABLET below 30°C
FAQs About PRIDILAN 40 TABLET
Does PRIDILAN 40 TABLET affect the ability to drive?
PRIDILAN 40 TABLET causes dizziness and sleepiness. So, avoid driving, doing machinery work or anything that needs attention. Consult your physician for advice.
Can PRIDILAN 40 TABLET cause bleeding?
PRIDILAN 40 TABLET might worsen the bleeding and thus it is not recommended for use in patients having bleeding disorders. Consult your doctor if you experience any kind of bleeding and it bothers you.
Can I have alcohol after taking PRIDILAN 40 TABLET?
Avoid consumption of alcohol while taking PRIDILAN 40 TABLET as it can increase the dizziness and affect your ability to perform activities that need alertness. Consult your physician for advice.
Is it safe to take PRIDILAN 40 TABLET in patients with heart problems?
PRIDILAN 40 TABLET is not recommended for use in patients having heart problems, especially arrhythmias (slow or fast heartbeat). Consult your doctor for advice. The doctor will determine a proper dose of PRIDILAN 40 TABLET or select a suitable alternative management for you.
Can PRIDILAN 40 TABLET be used in pregnant women?
PRIDILAN 40 TABLET is generally not recommended for use in pregnant women unless considered clearly necessary as it is not known whether this medicine will be harmful to an unborn baby. If you are pregnant, think you may be pregnant or are planning to have a baby, consult your doctor before taking it.
References
1. K.D. Tripathi. Adrenergic System and Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 136.
2. Azin Alavi, Minoo Rajaee, Malihe Amirian, Hamidreza Mahboobi, Keramat Allah Jahanshahi and Armaghan Faghihi. Effect of Maintenance Therapy with Isoxsuprine in the Prevention of Preterm Labor: Randomized controlled trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. August 2015. [Accessed on 9th July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578532/
3. Jaju PB. Effectiveness and Safety of Isoxsuprine Hydrochloride as Tocolytic Agent in Arresting Active/Threatened Preterm Labor and Its Role in Maintenance Tocolysis: A Prospective, Open-Label Study. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. February 2021. [Accessed on 9th July 2022]. https://pubmed.ncbi.nlm.nih.gov/31550735/
4. FDA.report. Isoxsuprine. [Accessed on 9th July 2022]. https://fda.report/DailyMed/6baec489-724b-4184-9529-7b9ca3573025
5. MK Medicine. Isoxsuprine HCL 40Mg (Sustain Release) Tablet. [Accessed on 9th July 2022]. https://www.mkmedicine.in/isoxsuprine-hcl-40mg-(sustain-release)-tablet.html
6. DM Pharma. Isoxsuprine HCl 40 mg. [Accessed on 9th July 2022]. http://www.dmpharma.co.in/Isoxsuprine%20Tablet.html
7. Aalaina pharma. Isoxsuprine HCl 40 mg. [Accessed on 9th July 2022]. https://alainapharma.com/Isoxsuprine%20Tablet.html
8. Kabir life science. Oxen 10 (Isoxsuprine Hydrochloride Tablets 10 mg). [Accessed on 9th July 2022]. https://www.kabirlifescience.com/product/oxen-10
9. Taj Pharma. Adrenilan (Isoxsuprine Hydrochloride Sustained Release Tablet 10 and 40 mg). [Accessed on 9th July 2022]. https://meds.tajpharma.com/portfolio-item/isoxsuprine-hydrochloride-sustained-release-tablet-adrenilan/
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