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Introduction About PREGCLEAR 200MG TABLET
PREGCLEAR 200MG TABLET contains Misoprostol which belongs to the group of medicines called Prostaglandin Analogs. It is used to manage peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen).
It can also be used for cervical ripening (dilation) prior to certain uterine procedures and for inducing labour pain. It is also used in combination with mifepristone (an abortion pill) to induce abortion during the early stages of pregnancy (first trimester) and can manage excessive blood loss after childbirth.
Take PREGCLEAR 200MG TABLET with meals to avoid stomach upset. Avoid taking antacids (containing magnesium) along with this medicine as it may increase the risk of severe stomach problems.
Before taking PREGCLEAR 200MG TABLET inform your doctor if you previously delivered your baby via caesarean section. You must also inform your doctor if you have any heart problems, high or low blood pressure, inflammatory bowel diseases or problems in blood vessels as a precaution.
Pregnant women should not get themselves exposed to this medicine as it may cause abortion or serious birth defects in the growing baby. It is also not suitable for use in breastfeeding women and in children aged below 18 years. Women of childbearing potential must use a suitable contraceptive method to avoid becoming pregnant while taking this medicine.
The most common side effects of taking PREGCLEAR 200MG TABLET are skin rashes, diarrhea, headache, dizziness, stomach pain, constipation, bloating, indigestion, birth defects (if accidentally exposed during pregnancy), vaginal bleeding (even after menopause) and severe uterine cramps. Consult your doctor if any of these side effects trouble you.
Uses Of PREGCLEAR 200MG TABLET
- Manage and manages peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen)
- Used for cervical ripening (prior to certain uterine procedures)
- Used for inducing labour pain
- Can induce abortion during the first trimester of pregnancy
- Prevents excessive blood loss after childbirth
How PREGCLEAR 200MG TABLET Works
PREGCLEAR 200MG TABLET reduces excessive stomach acid secretion caused due to prolonged NSAIDs use. This action heals the existing ulcers, manages new ulcers formation and provides relief from the unpleasant symptoms of GI tract (such as acidity and heartburn).
It also stimulates the contraction of uterine muscles which helps in initiating labour pain, reducing postpartum bleeding and for inducing abortion during the early stages of pregnancy. It also degrades the cells and tissues around the cervix, which helps in cervical ripening (softening) prior to uterine procedures.
How to use PREGCLEAR 200MG TABLET
Take PREGCLEAR 200MG TABLET with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects Of PREGCLEAR 200MG TABLET
Common
- skin rash
- diarrhea
- headache, dizziness
- stomach pain, constipation, bloating, indigestion
- nausea, vomiting
- birth defects (if accidentally exposed during pregnancy)
Uncommon
- fever
- irregular periods, severe uterine pain
- vaginal bleeding (among menopausal or older women)
Rare
Stop taking PREGCLEAR 200MG TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body, difficulty in breathing or swallowing, swelling of hands and legs)
- painful, prolonged heavy menstrual bleeding, abnormal uterine contractions
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take PREGCLEAR 200MG TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedDo not take PREGCLEAR 200MG TABLET if you are pregnant, think you may be pregnant or planning to have a baby, as this medicine may cause abortion or serious birth defects in the growing baby. PREGCLEAR 200MG TABLET should be used under careful medical supervision if abortion of the foetus is considered necessary by the physician. Women of childbearing potential must use a suitable contraceptive method to avoid becoming pregnant while taking this medicine. Stop taking PREGCLEAR 200MG TABLET and contact your doctor immediately if you accidentally became pregnant while taking PREGCLEAR 200MG TABLET.
Breastfeeding
ContraindicatedPREGCLEAR 200MG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by PREGCLEAR 200MG TABLET.
Allergy
ContraindicatedDo not take PREGCLEAR 200MG TABLET if you are allergic to Misoprostol or to any other ingredients of this medicine.
Heart Disease
Use with CautionPREGCLEAR 200MG TABLET should be used with caution in patients with heart problems or high or low blood pressure. Therefore, consult your doctor before taking it.
Others
Before taking PREGCLEAR 200MG TABLET inform your doctor if you:
- previously delivered a baby via caesarean section
- have any problems in blood vessels
- have inflammation in the bowel (such as ulcerative colitis, Crohn’s disease)
- are more prone to dehydration easily
Use in Paediatrics:
PREGCLEAR 200MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in Geriatrics:
PREGCLEAR 200MG TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking PREGCLEAR 200MG TABLET inform your doctor if you are taking any of the following medicines such as:
- antacids (used to neutralize stomach acid) such as aluminium hydroxide, magnesium hydroxide
- medicines used to manage heart problems (such as captopril, enalapril, lisinopril, amlodipine, nifedipine, diltiazem, verapamil, digoxin, methyldopa, amiodarone)
Overdosage:
If you or anyone else accidentally took more PREGCLEAR 200MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Misoprostol |
| Pharmacological Category | : | Prostaglandin Analogs |
| Therapeutic Indication | : | Peptic ulcer, Cervical Ripening, Abortifacient, Induction of labour pain |
| Dosage Forms | : | Tablet |
More Information
- Keep PREGCLEAR 200MG TABLET out of reach of children
- Store PREGCLEAR 200MG TABLET below 30°C
FAQs About PREGCLEAR 200MG TABLET
Q: What is the use of PREGCLEAR 200MG TABLET?
A: PREGCLEAR 200MG TABLET is used to manage peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen). It can also be used for cervical ripening (dilation) prior to certain uterine procedures and for inducing labour pain. It is also used in combination with mifepristone (an abortion pill) to induce abortion during the early stages of pregnancy (first trimester) and can manage excessive blood loss after childbirth.
Q: How PREGCLEAR 200MG TABLET works?
A: PREGCLEAR 200MG TABLET heals peptic ulcers by reducing excessive stomach acid secretion caused due to prolonged NSAIDs use. It also stimulates the contraction of uterine muscles which helps in initiating labour pain, reducing postpartum bleeding and for inducing abortion during the early stages of pregnancy. It also degrades the cells and tissues around the cervix, which helps in cervical ripening (softening) prior to uterine procedures.
Q: How should I take PREGCLEAR 200MG TABLET?
A: Take PREGCLEAR 200MG TABLET with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: What are the common side effects of taking PREGCLEAR 200MG TABLET?
A: The most common side effects of taking PREGCLEAR 200MG TABLET are skin rashes, diarrhea, headache, dizziness, stomach pain, constipation, bloating, indigestion, birth defects (if accidentally exposed during pregnancy), vaginal bleeding (even after menopause) and severe uterine cramps. Consult your doctor if any of these side effects trouble you.
Q: What precautions need to be followed while taking PREGCLEAR 200MG TABLET?
A: Take PREGCLEAR 200MG TABLET with meals to avoid stomach upset. Avoid taking antacids (containing magnesium) along with this medicine as it may increase the risk of severe stomach problems. Before taking PREGCLEAR 200MG TABLET inform your doctor if you previously delivered your baby via caesarean section. You must also inform your doctor if you have any heart problems, high or low blood pressure, inflammatory bowel diseases or problems in blood vessels as a precaution. Pregnant women should not get themselves exposed to this medicine as it may cause abortion or serious birth defects in the growing baby.
Q: Can PREGCLEAR 200MG TABLET be used in children?
A: PREGCLEAR 200MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Q: Can PREGCLEAR 200MG TABLET be used in post-menopausal women?
A: PREGCLEAR 200MG TABLET can be used in post-menopausal women. However, consult your doctor for advice before taking it.
Q: Can the use of PREGCLEAR 200MG TABLET cause unexpected bleeding?
A: Yes. Irregular vaginal bleeding or spotting may occur while you are taking PREGCLEAR 200MG TABLET. Consult your doctor if you experience prolonged painful bleeding.
Q: What to do if I forgot to take PREGCLEAR 200MG TABLET?
A: If you forgot to take a dose of PREGCLEAR 200MG TABLET, take it as soon as you remember. However, if it is time for the next dose of PREGCLEAR 200MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of PREGCLEAR 200MG TABLET to compensate the missed ones.
Q: Will the use of PREGCLEAR 200MG TABLET change the length of menstrual cycle?
A: Yes. PREGCLEAR 200MG TABLET may delay your regular menstrual periods. Also, there are chances for sudden spotting or vaginal bleeding while taking PREGCLEAR 200MG TABLET. But there is no reported evidence for long menstrual cycles.
References
1. KD. Tripathi. Prostaglandins, Leukotrienes and Platelet activation factor. Estrogens, Progestins and Contraceptives. Oxytocin and other drugs acting on the uterus. Drugs for Peptic ulcer and GERD. Essentials of medical pharmacology. Seventh edition. 2013. Page – 190, 319, 332 & 654.
2. Marissa Krugh; Christopher V. Maani. Misoprostol. StatPearls. NIH National Library of Medicine. National Center for biotechnology information. PMC. PubMed Central. July 2022. [Accessed on 30th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK539873/
3. Pfizer Limited. Cytotec 200 microgram Tablets Misoprostol. Electronics Medicines Compendium. [Revised in October 2020]. [Accessed on 30th January 2023] https://www.medicines.org.uk/emc/files/pil.1642.pdf
4. Zydus Pharmaceuticals USA Inc. Misoprostol Tablets. Dailymed.com. [Revised in January 2023]. [Accessed on 30th January 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d5a40157-ec43-4918-b2d8-d7a4c17e3acd
5. Cipla Ltd. Misoprost 25/200/600 Tablets (Misoprostol). Ciplamed.com. [Revised in January 2016]. [Accessed on 30th January 2023] https://ciplamed-library.com/content/misoprost-25-200-600-tablets
6. Central Drugs Standard Control Organization. Misoprostol tablet 25mcg/100mcg/200mcg (additional strength indication). December 2006. Misoprostol 50Mcg tablet (Additional Strength). August 2008. Misoprostol. June 2001. Misoprostol Tablet 600mcg. January 2009. [Accessed on 30th January 2023] https://cdscoonline.gov.in/CDSCO/Drugs


