Posid 50mg Capsule 8'S

Introduction About POSID 50MG CAPSULE

POSID 50MG CAPSULE contains Etoposide which belongs to the group of medicines called Anticancer agents. It is used to manage various types of cancer such as small cell lung cancer, blood cancer, lymph cancer, ovarian cancer and testicular cancer.

POSID 50MG CAPSULE must be taken on an empty stomach. During management with POSID 50MG CAPSULE, your doctor will periodically monitor your heart, liver and kidney function as a precaution.

Before taking POSID 50MG CAPSULE, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any serious infections, low albumin levels in blood or recently received any vaccine or radiotherapy or chemotherapy as a precaution.

Do not take POSID 50MG CAPSULE without consulting your doctor if you are pregnant or breastfeeding. Both men and women taking this medicine, must use a suitable contraceptive to stop pregnancy from occurrence during management with POSID 50MG CAPSULE and until 6 months after stopping the therapy.

The most common side effects of taking POSID 50MG CAPSULE are blood disorders, loss of appetite, constipation, pigmentation on the skin, temporary hair loss, weakness, tiredness and sore lips, mouth or throat ulcers. Consult your doctor if any of these side effects worsen.

Uses Of POSID 50MG CAPSULE

It is used to manage various types of cancer in adults such as:

• Small cell lung cancer
• Blood cancer (Ex. acute myeloid leukaemia)
• Lymph cancer (Ex. Hodgkin’s lymphoma, non-Hodgkin’s lymphoma)
• Ovarian cancer
• Testicular cancer

How POSID 50MG CAPSULE Works

POSID 50MG CAPSULE is an anticancer agent. It works by blocking the abnormal actions of certain cellular proteins (topoisomerase 2) that triggers cancer cell formation. As a result, it reduces cancer formation and stops its further growth within the body.

How to use POSID 50MG CAPSULE

Take POSID 50MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. POSID 50MG CAPSULE must be taken on an empty stomach.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take POSID 50MG CAPSULE for the stipulated duration instructed by your doctor to achieve better results.

Side Effects Of POSID 50MG CAPSULE

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.

Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.

Skin rash Or Itching

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.

Warning & Precautions

Pregnancy

Contraindicated

POSID 50MG CAPSULE is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it. Women of childbearing potential must use a suitable contraceptive method to manage pregnancy while taking POSID 50MG CAPSULE and until 6 months after stopping the therapy.

Breastfeeding

Contraindicated

POSID 50MG CAPSULE may pass through breast milk. Therefore, it is not recommended for use in breast-feeding women. Kindly consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if your ability is affected by POSID 50MG CAPSULE.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking POSID 50MG CAPSULE to avoid unwanted reactions.

Kidney

Use with Caution

POSID 50MG CAPSULE should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.

Liver

Use with Caution

POSID 50MG CAPSULE should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take POSID 50MG CAPSULE if you are allergic to Etoposide.

Use In Pediatrics

Consult your doctor

The safety and effectiveness of POSID 50MG CAPSULE have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use In Geriatrics

Use with Caution

POSID 50MG CAPSULE should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking POSID 50MG CAPSULE inform your doctor if you are taking any of the following medicines such as:

• live vaccines (including yellow fever vaccine)
• ciclosporin (a medicine used to suppress immune function and to stop graft rejection post-transplant)
• cisplatin (another medicine used to manage cancer)
• medicines used to manage epilepsy (such as phenytoin, carbamazepine)
• warfarin (a medicine used to stop blood clot formation)
• medicines used for pain relief (such as phenylbutazone, sodium salicylate, or aspirin)
• other medicines used for cancer such as anthracyclines (Ex. doxorubicin, epirubicin, daunorubicin)

Over dosage:

If you or anyone else accidentally take too much of POSID 50MG CAPSULE, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep POSID 50MG CAPSULE out of reach of children
• Store POSID 50MG CAPSULE at room temperature

FAQs About POSID 50MG CAPSULE

Q: How does POSID 50MG CAPSULE works?

A: POSID 50MG CAPSULE is an anticancer agent. It works by blocking the abnormal actions of certain cellular proteins (topoisomerase 2) that triggers cancer cell formation. As a result, it reduces cancer formation and stops its further growth within the body.

Q: Can I take POSID 50MG CAPSULE during breastfeeding?

A: No. POSID 50MG CAPSULE is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.

Q: Can POSID 50MG CAPSULE increase the risk of infections?

A: POSID 50MG CAPSULE may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while taking POSID 50MG CAPSULE. To avoid this, your doctor will regularly monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

Q: Can the use of POSID 50MG CAPSULE make me feel tired?

A: Yes. POSID 50MG CAPSULE may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anaemic. Consult your doctor if you experience tiredness after taking POSID 50MG CAPSULE. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while taking this medicine.

Q: Can I drive a car after taking POSID 50MG CAPSULE?

A: POSID 50MG CAPSULE may make you feel tired or dizzy. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by POSID 50MG CAPSULE.

Q: How to take POSID 50MG CAPSULE?

A: Take POSID 50MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. POSID 50MG CAPSULE must be taken on an empty stomach.

Q: What should I do if I forget to take a dose of POSID 50MG CAPSULE?

A: If you forget to take a dose of POSID 50MG CAPSULE, or vomited immediately after taking the dose, take it as soon as you remember. Do not take the medicine twice to make up for the forgotten dose.

Q: How to control nausea caused due to POSID 50MG CAPSULE?

A: Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with POSID 50MG CAPSULE. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-manage nausea.

References

1. KD. Tripathi. Anticancer Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 866.

2. Gizem Reyhanoglu; Prasanna Tadi. Etoposide. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 11th February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336826/

3. Corden Pharma Latina S.p.A. Etoposide 50 mg and 100 mg capsules, soft. Electronics Medicines Compendium. [Revised in July 2022] [Accessed on 11th February 2023] https://www.medicines.org.uk/emc/files/pil.6292.pdf

4. Central Drugs Standard Control Organization. Etoposide Capsule and Injection. March 1988.  [Accessed on 11th February 2023] https://cdscoonline.gov.in/CDSCO/Drugs

Useful Diagnostic Tests

• Beta Human Chorionic Gonadotropin, Tumour marker

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 12 Dec 2023 | 03:37 PM(IST)