Planep T 10mg Kit 10's

Introduction About PLANEP T 10MG KIT

PLANEP T 10MG KIT is a combination of Eplerenone and Torsemide which belongs to the group of medicines called Diuretics. It is used in adults to manage high blood pressure and edema (swelling due to fluid retention) related to heart failure.

Hypertension is defined as persistently increased blood pressure, that can show symptoms like headache, sweating, fast heartbeat or throbbing sensation. Fluid regularly drains into body tissues from the blood. When this fluid isn’t removed from the tissue, fluid retention (edema) occurs, causing symptoms like swelling and aching of affected body parts such as feet, ankles or hands.

During course of the management your doctor might regularly monitor your kidney or liver function test to avoid any untoward side effects.

Before taking PLANEP T 10MG KIT, inform your doctor if you have any kidney, heart or liver problems, high or low blood potassium levels, diabetes, low blood volume or difficulty in passing urine.

PLANEP T 10MG KIT is not recommended for use in pregnant and breastfeeding women, so consult your doctor before taking it. It is not recommended for use in children and adolescents due to lack of safety and effectiveness.

The most common side effects of taking PLANEP T 10MG KIT are muscle cramps, diarrhoea, nausea, dizziness, headache and constipation. Consult your doctor if any of the above side effects worsen.

Uses Of PLANEP T 10MG KIT

• Manage high blood pressure and edema related to heart failure

How PLANEP T 10MG KIT Works

PLANEP T 10MG KIT lowers edema where eplerenone blocks aldosterone, which is a mineralocorticoid acting on epithelial (e.g., kidney) and nonepithelial (e.g., heart and blood vessels) receptors to cause sodium and water reabsorption, and torsemide induces excretion of sodium, chloride and water by inhibiting sodium and chloride reabsorption in kidney tubules.

How to use PLANEP T 10MG KIT

Take PLANEP T 10MG KIT as advised by your physician. Swallow PLANEP T 10MG KIT with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking PLANEP T 10MG KIT unless your doctor advises you to stop.

Side Effects Of PLANEP T 10MG KIT

How To Manage Side Effects

Nausea and vomiting:

Take this medicine with or just after a meal or a snack and stick to simple meals and do not eat oil rich or spicy food. Consult your doctor if the symptom does not improve.

Headache:

Take rest and drink plenty of water. Avoid taking alcohol and skipping meals. Do not strain your eyes by watching the screen for long time. Consult your doctor if the symptom persists for long or gets worsened.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.

Diarrhea:

Drink lot of fluids such as water or fruit juice to keep yourself hydrated. Do not consume any medicine other than PLANEP T 10MG KIT without consulting your doctor.

Warning & Precautions

Pregnancy

PLANEP T 10MG KIT is not recommended for use in pregnant women, as it is not known if it causes any potential harm to the unborn baby. Consult your doctor before taking PLANEP T 10MG KIT.

Breastfeeding

PLANEP T 10MG KIT is not recommended for use in breastfeeding women as it is not known if it passes into breast milk. Consult your doctor before taking PLANEP T 10MG KIT.

Driving and Using Machines

Do not drive or use any machine if you feel dizzy after taking PLANEP T 10MG KIT.

Kidney

PLANEP T 10MG KIT is not recommended for use in patients with kidney problems. It should be used with caution in patients with kidney disease. Consult your doctor before taking PLANEP T 10MG KIT.

Liver

PLANEP T 10MG KIT is not recommended for use in patients with liver problems. It should be used with caution in patients with liver disease. Consult your doctor before taking PLANEP T 10MG KIT.

Allergy

Do not take PLANEP T 10MG KIT if you are allergic to Eplerenone, Torsemide or any other ingredients of this medicine.

Heart Disease

PLANEP T 10MG KIT is not recommended for use in patients having low blood pressure or irregular heartbeats. Consult your doctor before taking PLANEP T 10MG KIT.

Interactions

A. Drug - Drug interactions:

Before taking PLANEP T 10MG KIT, inform your doctor if you are taking any of the following medicines:

• medicines used to manage fungal infections (Ex. itraconazole, ketoconazole, fluconazole, miconazole)
• medicines used to manage HIV (Ex. ritonavir, nelfinavir, saquinavir)
• medicines used to manage bacterial infections (Ex. clarithromycin, telithromycin, erythromycin, trimethoprim, rifampicin, streptomycin, gentamycin, cephalexin, ceftriaxone)
• medicines used to manage depression (Ex. nefazodone, amitriptyline, amoxapine, St. John’s Wort)
• drugs which help you to excrete excess body fluid (Ex. spironolactone, amiloride)
• medicines used to manage heart conditions like high blood pressure or heart insufficiency (Ex. lisinopril, enalapril, olmesartan, candesartan, prazosin, alfuzosin, digoxin, amiodarone, diltiazem, verapamil)
• lithium (used to manage bipolar disorder)
• medicines used after organ transplantation (Ex. cyclosporin, tacrolimus)
• medicines used to relieve pain, stiffness, and inflammation (Ex. aspirin, ibuprofen, indomethacin)
• medicines used to manage psychiatric disorders (Ex. chlorpromazine, haloperidol)
• medicines used during cancer chemotherapy (Ex. amifostine, cisplatin)
• baclofen (used to manage muscle spasm)
• medicines used to manage inflammation and certain skin conditions (Ex. hydrocortisone, prednisone, dexamethasone)
• tetracosactide (used in diagnosis and management of adrenal cortex disorders)
• medicines used to manage fits (Ex. carbamazepine, phenytoin, phenobarbital)
• medicines used to manage high blood sugar (Ex. chlorpropamide, glibenclamide, glipizide, tolbutamide)
• adrenaline (used to manage low blood pressure)
• cholestyramine (used to manage high blood cholesterol levels)
• medicines used to manage constipation (Ex. methylcellulose, psyllium)
• probenecid (used to manage gout)
• theophylline (used to manage asthma)
• oxandrolone (used to promote weight gain)
• substances used to enhance the visibility of internal structures in CT scan and other tests (Ex. iodinated contrast media, ionic iodinated contrast media)

Overdosage:

If you or anyone else accidentally takes too much of PLANEP T 10MG KIT, contact your doctor immediately or visit the nearby hospital. Symptoms of PLANEP T 10MG KIT overdose includes low blood pressure (signs include light-headedness, dizziness, blurred vision, weakness, acute loss of consciousness), high blood potassium levels (signs include muscle cramps, diarrhea, nausea, dizziness, headache), passing a lot of urine, sleepiness, confusion, fainting or dizzy and stomach upset.

Synopsis

More Information

• Keep PLANEP T 10MG KIT out of reach of children
• Store PLANEP T 10MG KIT at room temperature

FAQs About PLANEP T 10MG KIT

Q: Can PLANEP T 10MG KIT be used in children?

A: PLANEP T 10MG KIT is not recommended for use in children and adolescents as its safety and effectiveness have not been established. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

Q: Is PLANEP T 10MG KIT safe during pregnancy?

A: PLANEP T 10MG KIT is not recommended for use in pregnant women, as it is not known if it causes any potential harm to the unborn baby. If you are pregnant, think you may be pregnant or are planning to get pregnant, inform your doctor before taking PLANEP T 10MG KIT.

Q: What precautions do I need to follow while taking PLANEP T 10MG KIT?

A: Patients taking PLANEP T 10MG KIT must inform their doctor if they have diabetes, kidney, liver or heart problems, if they are pregnant, breast-feeding, having any allergies, high or low blood potassium levels, low blood volume or difficulty in passing urine. Contact your doctor immediately if you have any unusual symptoms while taking PLANEP T 10MG KIT.

Q: Can PLANEP T 10MG KIT cause constipation?

A: Yes, constipation is a common side effect of PLANEP T 10MG KIT. In such case, eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals and drink plenty of water and exercise more regularly. Tell your doctor if your constipation doesn’t resolve.

Q: Is PLANEP T 10MG KIT safe to use in patients with kidney problems?

A: PLANEP T 10MG KIT is not recommended for use in patients with kidney problems. It should be used with caution in patients with kidney disease. Consult your doctor before taking it.

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Hypertension. Pharmacotherapy Handbook. Ninth edition. Page-87

2. Tejaswi Kanderi; Pradeep Vaitla. Torsemide. StatPearls [Internet]. July 2021. [Accessed on 3rd June 2022] https://www.ncbi.nlm.nih.gov/books/NBK559175/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,K%2B%2F2Cl%2D%20cotransport%20mechanism

3. Jonathan C. Hughes; Manouchkathe Cassagnol. Eplerenone. StatPearls [Internet]. May 2022. [Accessed on 3rd June 2022] https://www.ncbi.nlm.nih.gov/books/NBK553100/#article-21264.s3

4. S.C.Zentiva S.A. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 3rd June 2022] https://www.medicines.org.uk/emc/files/pil.3665.pdf

5. MEDA Pharma GmBH and Co. KG. Electronic Medicines Compendium (EMC). [Revised in August 2019] [Accessed on 3rd June 2022] https://www.medicines.org.uk/emc/files/pil.6663.pdf

6. Torsemide. DailyMed; National Library of Medicine; National Institute of Health. [Revised in February 2022] [Accessed on 3rd June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=55e88727-864e-4313-860c-31a6ca45168f#Section_5.3

7. Eplerenone. DailyMed; National Library of Medicine; National Institute of Health. [Revised in March 2022] [Accessed on 3rd June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d953457e-0aff-6c38-e053-2995a90a7d32

Useful Diagnostic Tests

• Kidney function test

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 23 Dec 2022 | 05:05 PM(IST)