Placida Plus Tablet 10'S

Introduction About PLACIDA PLUS TABLET

PLACIDA PLUS TABLET is a combination of Escitalopram and Etizolam which belongs to the group of medicines called Antidepressants and Anxiolytics respectively. It is used to manage depression, obsessive-compulsive disorder, major depressive episodes, panic disorder, anxiety disorder and insomnia.

PLACIDA PLUS TABLET is not recommended for use in patients with myasthenia gravis, acute angle-closure glaucoma, sleep disorder and porphyria. Contact your doctor before taking. Before taking PLACIDA PLUS TABLET inform your doctor if you have lung, liver or kidney disease or heart disease. Contact your doctor before taking. PLACIDA PLUS TABLET is not recommended in pregnant and breastfeeding women. Contact your doctor before taking.

Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Contact your doctor before taking. PLACIDA PLUS TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking. The most common side effects of this medicine are confusion, nausea, vomiting, diarrhea, memory impairment, drowsiness and tiredness. Contact your doctor if any of the side effects worsen.

Uses Of PLACIDA PLUS TABLET

It is used to manage:

• depression
• obsessive-compulsive disorder
• major depressive episodes
• panic disorder
• anxiety disorder and
• insomnia

How PLACIDA PLUS TABLET Works

PLACIDA PLUS TABLET is a combination of Escitalopram and Etizolam. Escitalopram increases the levels of serotonin, a chemical messenger that improves mood. Etizolam increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

How to use PLACIDA PLUS TABLET

Take PLACIDA PLUS TABLET as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depends on your age, body weight and disease condition.

Side Effects Of PLACIDA PLUS TABLET

How To Manage Side Effects

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if the symptom did not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling drowsy. Contact your doctor if the symptom did not improve.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Warning & Precautions

Pregnancy

Contraindicated

PLACIDA PLUS TABLET is not recommended in pregnant women. Contact your doctor before taking.

Breastfeeding

Contraindicated

PLACIDA PLUS TABLET is not recommended during breastfeeding. Contact your doctor before taking the medicine.

Driving and Using Machines

Use with Caution

Patients should be used with caution about operating, hazardous machines including automobiles. If you experience dizziness or drowsiness, lack of attentiveness, concentration or ability of reflexive motion, consult your doctor for advice.

Alcohol

Contraindicated

Consumption of alcohol is not recommended while taking PLACIDA PLUS TABLET. Consult your doctor for advice.

Kidney

Use with Caution

PLACIDA PLUS TABLET should be used with caution in patients with kidney function. Contact your doctor before taking.

Liver

Contraindicated

PLACIDA PLUS TABLET is not recommended for use in patients with liver impairment. Contact your doctor before taking.

Allergy

Contraindicated

Do not take PLACIDA PLUS TABLET if you are allergic to Escitalopram, Etizolam or to any other ingredients of this medicine.

Lungs

Consult your doctor

PLACIDA PLUS TABLET is not recommended for use in patients with severe respiratory failure. It should be used with caution in patients with history of lung insufficiency. Contact your doctor before taking.

Heart Disease

Use with Caution

PLACIDA PLUS TABLET should be used with caution in patients with recent history of myocardial infarction or unstable heart disease. Contact your doctor before taking.           

Use In Pediatrics

Consult your doctor

Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Contact your doctor before taking PLACIDA PLUS TABLET.

Use In Geriatrics

Use with Caution

PLACIDA PLUS TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking.

Interactions

A. Drug-Drug interactions:

Before taking PLACIDA PLUS TABLET inform your physician if you are taking the following medicine:

• monoamine oxidase inhibitor, lithium (used to manage depression)
• triptans, sumatriptan (used to manage migraine)
• CNS depressants phenothiazines, barbiturates
• NSAIDS, aspirin (used to relieve pain)
• warfarin (manages blood clot)
• cimetidine (used to manage ulcers)
• digoxin (used to manage heart problems)
• pimozide (manages psychotic disorders)
• theophylline (manages breathing conditions)
• carbamazepine (used to manage seizures)
• triazolam (used to manage insomnia)
• ketoconazole (used to manage fungal infections)
• ritonavir (used to manage HIV infection)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are convulsions, dizziness, hypotension, insomnia, nausea, vomiting, somnolence, and ECG changes.

Synopsis

More Information

• Keep out of reach of children
• Store PLACIDA PLUS TABLET at a temperature not exceeding 30°C

FAQs About PLACIDA PLUS TABLET

Q: For what conditions PLACIDA PLUS TABLET is used?

A: PLACIDA PLUS TABLET is used to manage depression, obsessive-compulsive disorder, major depressive episodes, panic disorder, anxiety disorder and insomnia.

Q: What are the side effects of taking PLACIDA PLUS TABLET?

A: The most common side effects of this medicine are confusion, nausea, vomiting, diarrhea, memory impairment, drowsiness and tiredness. Consult your doctor for advice.

Q: How PLACIDA PLUS TABLET works?

A: PLACIDA PLUS TABLET is a combination of Escitalopram and Etizolam. Escitalopram increases the levels of serotonin, a chemical messenger that improves mood. Etizolam increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Q: Can I drink alcohol while using PLACIDA PLUS TABLET?

A: No. Avoid consumption of alcohol while taking PLACIDA PLUS TABLET as it may increase unwanted side effects.

Q: Can I use PLACIDA PLUS TABLET in children?

A: Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Contact your doctor before taking PLACIDA PLUS TABLET.

References

1. K.D. Tripathi. Drugs acting on the CNS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 433, 436, 439.

2. Jill Mathews, Suresh V. Dange, Angana Dutta, Abhijeet V. Tilak, Shrikrishna S. Shende, Sayan Das. An observational study of the effect of escitalopram and etizolam in type 2 diabetes mellitus patients with depression. Sep-Oct 2016. [Accessed on Feb 25th 2023] https://www.ijbcp.com/index.php/ijbcp/article/view/664

3. Torrent Pharmaceuticals Ltd. [Accessed on Feb 25th 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2702.pdf

4. Leeford. [Accessed on Feb 25th 2023] https://www.leeford.in/product/952/escipil-et

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Aravindan Balachandran - MBBS, MD (Psychiatry)

Last updated on 25 Feb 2023 | 06:33 PM(IST)