Pioz 7.5mg Tablet 10'S
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Introduction About PIOZ 7.5MG TABLET
Pioz 7.5mg Tablet is an oral anti-diabetic medicine containing Pioglitazone, which belongs to the thiazolidinedione (glitazone) class of drugs. It works by improving the body’s sensitivity to insulin, thereby helping in better control of blood sugar levels. This medicine is commonly prescribed to adults with type 2 diabetes mellitus, especially when diet, exercise, or other medicines alone do not provide adequate control. By lowering blood sugar, it helps reduce the risk of diabetes-related complications such as kidney problems, nerve issues, and heart disease.
This tablet is generally suitable for patients who need additional support in achieving stable blood sugar levels and may be prescribed as monotherapy or along with other medicines like metformin, sulfonylureas, or insulin. It is particularly considered in patients with insulin resistance and those struggling with fluctuating sugar levels despite lifestyle modifications. However, it is not used in type 1 diabetes or for diabetic ketoacidosis.
It should be taken once daily, with or without food, at the same time each day for maximum benefit. The dose is individualized based on the patient’s blood sugar profile and doctor’s recommendation. Regular monitoring of blood glucose and HbA1c is important while on this medication. It should always be combined with a healthy diet plan, exercise routine, and regular check-ups to get the best results.
Pioz 7.5mg Tablet should be used with caution in patients with liver or heart problems, as it may cause fluid retention or worsen heart failure. It is not recommended during pregnancy or breastfeeding due to limited safety data. Elderly patients should also use it under strict medical guidance. Common side effects may include weight gain, swelling (edema), headache, and muscle pain. Any unusual symptoms such as shortness of breath, rapid weight gain, or severe fatigue should be promptly reported to the doctor.
Uses Of PIOZ 7.5MG TABLET
- Type II diabetes mellitus in adults along with diet and exercise
Benefits of PIOZ 7.5MG TABLET
Pioz 7.5mg Tablet for Blood Sugar Control
Pioz 7.5mg Tablet is commonly prescribed for people with type 2 diabetes to help keep blood sugar levels within a healthy range. It works by making the body respond better to insulin, which lowers excess sugar in the blood. By improving blood sugar control, it helps reduce the risk of long-term diabetes-related complications such as kidney, heart, and nerve problems. This tablet is usually taken along with a healthy diet, regular exercise, and sometimes in combination with other diabetes medicines.
Pioz 7.5mg Tablet – Improve Insulin Sensitivity
The main benefit of Pioz 7.5mg Tablet is that it improves the body’s sensitivity to insulin. In type 2 diabetes, the body often produces insulin but cannot use it effectively, a condition known as insulin resistance. Pioz helps overcome this resistance, allowing muscles and fat cells to absorb and use glucose more efficiently. Unlike some medicines, it does not force the pancreas to release more insulin, which lowers the risk of sudden low blood sugar when taken alone. Over time, this improves overall blood sugar balance and helps in better diabetes management.
How PIOZ 7.5MG TABLET Works
Pioz 7.5mg Tablet – Mechanism of Action
Pioz 7.5mg Tablet contains Pioglitazone, which belongs to the group of medicines called thiazolidinediones (glitazones). It works mainly by targeting insulin resistance, which is the main problem in type 2 diabetes.
Pioglitazone activates a specific receptor in the body called PPAR-γ (Peroxisome Proliferator-Activated Receptor gamma). This activation improves how the body’s cells—especially those in muscles, fat, and the liver—respond to insulin. As a result, glucose is absorbed and used more effectively, reducing high blood sugar levels.
Unlike some other diabetes medicines, Pioz does not make the pancreas release more insulin. Instead, it helps the body use its natural insulin better. This action leads to improved long-term blood sugar control without causing sudden low sugar episodes when used alone.
How to use PIOZ 7.5MG TABLET
How to take Pioz 7.5mg tablet
- Take Pioz 7.5mg Tablet exactly as prescribed by your doctor; do not change the dose on your own.
- It can be taken with or without food but try to take it at the same time each day for best results.
- Swallow the tablet whole with a glass of water; do not crush or chew it.
- Your doctor may adjust the dose based on blood sugar levels, response, and overall health condition.
- Keep taking this medicine regularly even if you feel well, as stopping suddenly may cause your blood sugar to rise.
- Always follow your doctor’s advice on diet, exercise, and regular monitoring while taking this medicine.
What if I forgot to take PIOZ 7.5MG TABLET
If you forget to take a Pioz 7.5mg tablet, take it as soon as you remember unless it is nearly time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing routine. Do not take two doses at the same time to make up for the missed tablet, as this can increase your risk of side effects. Maintaining consistency helps your treatment work effectively, so try to take your medication at the same time each day.
Overdose
If you or anyone else accidentally took more pioz 7.5mg tablet, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include hypoglycaemia which may cause increased hunger, sweating, shakiness, weakness, or an irregular heartbeat.
Side Effects Of PIOZ 7.5MG TABLET
Common Side Effects of Pioz 7.5mg tablet:
- hypoglycaemia (low blood sugar levels causing dizziness, shakiness or hunger)
- headache, dizziness
- abnormal vision
- joint pain, back pain, muscle pain
- impotence
- shortness of breath, anaemia
- flatulence
- respiratory infection, sinus infection, sore throat
- weight gain
- numbness
- difficulty in sleeping (insomnia)
- sugar in urine
- proteins in urine
- spinning sensation (vertigo)
- sweating, tiredness
- increased appetite
When to Seek Medical Attention?
Stop taking Pioz 7.5mg tablet and contact your physician immediately if you experience any of the following side effects:
- symptoms of heart failure (such as unusual shortness of breath or trouble in breathing, rapid increase in weight or localised swelling (oedema), especially in the ankles or legs, unusual tiredness)
- signs and symptoms of bladder cancer (such as blood in your urine, pain while urinating or urgent need to pee)
- increased risk of fractures (especially in the bones of hand, upper arm, or foot in women)
- blurred vision due to swelling at the back of the eye or worsening of existing blurred vision
- serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
- signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)
How To Manage Side Effects
Headache
- Staying hydrated by drinking plenty of water helps prevent dehydration-related headaches.
- Resting in a quiet, dim room can ease headache pain.
- Applying a cold or warm compress on the forehead or neck provides relief.
- Practicing relaxation techniques such as deep breathing or meditation reduces tension.
- Using essential oils like peppermint or lavender on temples may soothe headache symptoms.
Sore Throat
- Warm saltwater gargle: Gargling with a glass of warm water mixed with ½ teaspoon of salt can reduce swelling and kill germs.
- Honey in warm water/tea: Honey has soothing and antibacterial properties. Mix it in warm water or herbal tea for relief.
- Ginger tea: Fresh ginger boiled in water helps reduce inflammation and provides comfort to a sore throat.
- Turmeric milk: Drinking warm milk with a pinch of turmeric (golden milk) can help ease throat irritation.
- Steam inhalation: Inhaling steam from hot water (you can add a few drops of eucalyptus oil) keeps the throat moist and reduces dryness.
- Stay hydrated: Drink plenty of warm fluids like soups, herbal teas, and warm water to keep the throat moist.
- Lozenges or warm candies: Sucking on lozenges or sugar-free candies can keep your throat moist and relieve dryness.
Warning & Precautions
Pregnancy
ContraindicatedPioz 7.5mg tablet is generally not recommended during pregnancy due to limited safety information. Consult your doctor before using it if you are pregnant or planning to become pregnant.
Breastfeeding
ContraindicatedThis medicine is not recommended for breastfeeding women, as it is unclear whether it passes into breast milk. Speak with your doctor before taking it while breastfeeding.
Driving and Using Machines
Use with CautionAvoid driving or operating heavy machinery if you experience vision changes or dizziness after taking Pioz 7.5mg ablet.
Alcohol
ContraindicatedAlcohol may increase the risk of side effects while taking this medicine. It is best to limit or avoid alcohol and discuss with your doctor.
Liver
Consult your doctorPioz 7.5mg tablet is not recommended for patients with severe liver disease. Use with caution if you have other liver conditions and consult your doctor before starting the medicine.
Allergy
ContraindicatedDo not take Pioz 7.5mg tablet if you are allergic to Pioglitazone or any other ingredient in the medicine.
Heart Disease
Consult your doctorThis medicine is not recommended for patients with severe heart problems such as heart failure. Use with caution if you have other heart conditions and consult your doctor beforehand.
Use In Pediatrics
ContraindicatedPioz 7.5mg tablet is not recommended for children or adolescents under 18 years. Consult your doctor before use.
Use In Geriatrics
Use with CautionElderly patients (65 years or older) should use Pioz 7.5mg tablet with caution. Consult your doctor before taking it.
Other Warnings for PIOZ 7.5MG TABLET
Before taking pioz 7.5mg tablet, inform your doctor if you:
- have fluid retention and swelling
- have other urinary problems
- smoke
- have special type of diabetic eye disease called macular oedema (swelling of the back of the eye with worsening of your vision)
- have cysts on your ovaries (polycystic ovary syndrome
- previously had stroke
- have anaemia (low RBC in blood)
- have any bone problems or at risk of developing bone fractures
- are a premenopausal woman
Who should not take [GBNKEYWORD
Pioz 7.5mg tablet is not recommended for use if you:
- have diabetic ketoacidosis (increased levels of ketone bodies in the blood)
- have bladder cancer
- pass bloody urine
Safety Advice
- Take Pioz 7.5mg Tablet exactly as prescribed by your doctor. Do not change the dose on your own.
- Monitor for signs of fluid retention, such as swelling in the feet, ankles, or hands, and report them to your doctor.
- Inform your doctor about all other medicines you are taking to avoid potential interactions.
- Do not use in children or adolescents under 18 years of age.
- Attend regular follow-ups so your doctor can monitor blood sugar, liver function, and overall response to therapy.
Diet and Lifestyle Advice
- Follow a balanced diet with plenty of vegetables, fruits, whole grains, and lean proteins to help manage blood sugar levels.
- Limit sugar and refined carbohydrates (like sweets, pastries, white bread) to avoid spikes in blood glucose.
- Maintain a moderate carbohydrate intake in each meal to support steady blood sugar control.
- Stay hydrated by drinking enough water throughout the day.
- Include regular physical activity like walking, swimming, or yoga, after consulting your doctor, to improve insulin sensitivity and overall health.
- Monitor your weight regularly; Pioglitazone may cause fluid retention or weight gain.
- Reduce intake of very salty or processed foods to minimize fluid retention.
- Take the medicine at the same time each day, preferably with or without food, to maintain consistent blood sugar control.
- Schedule regular check-ups with your doctor to monitor blood sugar, liver function, and overall health while on therapy.
1.Pioz 7.5mg Tablet and Pioz MF Tablet:
|
Feature |
Pioz 7.5mg Tablet |
Pioz MF Tablet |
|
Composition |
Contains only Pioglitazone (7.5mg) |
Combination of Pioglitazone + Metformin |
|
Mechanism of Action |
Improves insulin sensitivity in body tissues, helping the body use insulin better |
Dual action – Pioglitazone improves insulin sensitivity and Metformin reduces glucose production in the liver |
|
Use in Diabetes |
Prescribed when insulin resistance is the main concern |
Prescribed when both insulin resistance and high glucose production need control |
|
Suitable for Patients |
Those who cannot tolerate metformin or need only pioglitazone |
Patients who need stronger blood sugar control than pioglitazone alone can provide |
|
Risk of Side Effects |
May cause weight gain, edema, muscle pain |
May cause gastrointestinal issues (nausea, diarrhoea) along with pioglitazone-related effects |
|
Doctor’s Preference |
Used as monotherapy or with other agents if needed |
Preferred when dual therapy is required for better sugar control |
2. Pioz 7.5mg Tablet and Insulin injections in terms of long-term use:
|
Feature |
Pioz 7.5mg Tablet |
Insulin Injections |
|
Form |
Oral tablet, easy to swallow |
Injectable, requires needles and proper technique |
|
Mechanism |
Improves the body’s sensitivity to insulin |
Directly supplies insulin to the body |
|
Use in Diabetes |
Mostly for type 2 diabetes with insulin resistance |
For type 1 diabetes, advanced type 2 diabetes, or when oral medicines fail |
|
Convenience |
Easier to take daily, no injection required |
Requires regular injections, which some patients find difficult |
|
Risk of Low Sugar (Hypoglycaemia) |
Lower risk compared to insulin |
Higher risk, especially if dosage is not balanced with meals and activity |
|
Side Effects |
Weight gain, fluid retention, swelling in some cases |
Weight gain, risk of hypoglycaemia, injection-site reactions |
|
Long-term Suitability |
Safer for type 2 diabetes patients needing oral control |
Essential for type 1 diabetes and advanced type 2 diabetes; may be lifelong |
Drug - Drug interaction
1. Insulin or Other Antidiabetic Medicines
- Interaction: Using pioglitazone with insulin or sulfonylureas may increase the risk of low blood sugar (hypoglycaemia).
- Management: Blood sugar should be monitored closely, and your doctor may adjust the dose of one or both medicines.
2. Rifampicin, Phenytoin, or Carbamazepine (enzyme-inducing drugs)
- Interaction: These medicines can reduce the effectiveness of pioglitazone by increasing its breakdown in the liver.
- Management: Your doctor may adjust the dose of Pioz or consider alternative medications.
3. CYP2C8 Inhibitors (e.g., Gemfibrozil, Ketoconazole)
- Interaction: These drugs can increase pioglitazone levels in the body, raising the risk of side effects.
- Management: Dose adjustment or close monitoring for side effects may be required.
4. Estrogens, Oral Contraceptives, or Other Hormonal Therapies
- Interaction: May affect blood sugar control, potentially reducing pioglitazone’s effectiveness.
- Management: Blood sugar levels should be monitored regularly, and doses adjusted if necessary.
5. Diuretics or Drugs Affecting Kidney Function
- Interaction: Can increase the risk of fluid retention and swelling when taken with pioglitazone.
- Management: Your doctor may monitor weight, signs of swelling, and adjust medications as needed.
6. Other Liver-Metabolized Drugs
- Interaction: Drugs metabolized by the liver may interact with pioglitazone, altering its levels.
- Management: Regular liver function tests and monitoring for side effects are recommended.
Drug - Food interaction
1. High-Sugar Foods or Refined Carbohydrates
- Interaction: Foods high in sugar can reduce the effectiveness of pioglitazone in controlling blood glucose levels.
- Management: Follow a balanced diet with controlled carbohydrate intake to maintain steady blood sugar.
2. High-Fat Meals
- Interaction: Fatty meals can slow digestion and may delay the absorption of pioglitazone slightly.
- Management: Pioglitazone can still be taken with meals but aim for balanced meals to optimize effect.
3. Grapefruit and Grapefruit Juice
- Interaction: May slightly affect liver metabolism of certain medicines, including pioglitazone, though the effect is minor.
- Management: Occasional consumption is usually safe but discuss regular intake with your doctor.
4. Foods Affecting Sodium Balance (e.g., very salty foods)
- Interaction: Excess salt may worsen fluid retention, a possible side effect of pioglitazone.
- Management: Maintain a moderate-sodium diet and monitor for swelling or weight gain.
Synopsis
|
Drug |
Pioglitazone |
|
Pharmacological Category |
PPAR-gamma and PPAR-alpha agonists |
|
Therapeutic Indication |
Type II Diabetes mellitus |
|
Dosage Forms |
Tablet |
More Information
Storage
- Keep Pioz 7.5mg tablet out of the sight and reach of children
- Store Pioz 7.5mg tablet below 30°C
FAQs About PIOZ 7.5MG TABLET
Q: What is Pioz 7.5mg Tablet used for?
A: Pioz 7.5mg Tablet contains Pioglitazone, which is used to help control high blood sugar in people with type 2 diabetes. It works by making your body more sensitive to insulin, allowing better use of glucose. By lowering blood sugar, it reduces the risk of diabetes-related complications. It is usually prescribed along with diet and exercise changes. Sometimes, it may be combined with other diabetes medicines for better control. Always take it as advised by your doctor.
Q: How should I take Pioz 7.5mg Tablet?
A: Take the tablet exactly as prescribed by your doctor. It can be taken with or without food, preferably at the same time every day. Swallow the tablet whole with water, without crushing or chewing. Do not skip doses or take more than prescribed. If you miss a dose, take it when you remember unless it’s almost time for your next dose. In that case, skip the missed dose and continue as usual. Consistency is key for good blood sugar control.
Q: Can I take Pioz 7.5mg Tablet on an empty stomach?
A: Yes, you can take this medicine on an empty stomach, as food does not significantly affect its action. However, many people prefer taking it after a meal to avoid stomach discomfort. What’s more important is to take it at the same time every day. Regularity helps in maintaining a stable level of medicine in your body. Ask your doctor if you should follow any special meal instructions. Always follow the schedule advised by your doctor.
Q: Can I stop taking Pioz 7.5mg Tablet suddenly?
A: No, do not stop taking this medicine suddenly without your doctor’s advice. Stopping it abruptly may lead to uncontrolled blood sugar levels, which can cause tiredness, frequent urination, and long-term complications. If you are experiencing side effects or any concerns, speak with your doctor before stopping. Your doctor may adjust the dose or switch you to another medicine. Diabetes is a long-term condition, and medicines are often needed continuously. Never make changes to your treatment on your own.
Q: What are the common side effects of Pioz 7.5mg Tablet?
A: Some common side effects include weight gain, swelling in the legs or ankles, headache, and respiratory infections. It may also cause muscle pain, tiredness, or mild stomach upset in some people. Most side effects are mild and temporary. However, if swelling, sudden weight gain, or breathing difficulty occurs, seek medical advice immediately. Regular monitoring can help manage side effects early. Always discuss any unusual symptoms with your doctor.
Q: Does Pioz 7.5mg Tablet cause weight gain?
A: Yes, weight gain is a known side effect of this medicine. It may occur due to fluid retention and changes in fat distribution in the body. Not everyone experiences this effect, but it is more likely if the medicine is used long-term. To reduce the risk, maintain a healthy diet, exercise regularly, and monitor your weight. Report any rapid or unexplained weight gain to your doctor. They may adjust your dose or recommend lifestyle changes.
Q: Can Pioz 7.5mg Tablet cause low blood sugar?
A: Pioz 7.5mg Tablet by itself usually does not cause low blood sugar (hypoglycaemia). However, when combined with insulin or other diabetes medicines like sulfonylureas, the risk may increase. Symptoms of low blood sugar include sweating, dizziness, shakiness, and hunger. If this happens, take a small snack or glucose tablet immediately. Always carry something sweet if you are on combination therapy. Inform your doctor if you experience frequent hypoglycaemia. Dose adjustments may be required.
Q: How long does it take for Pioz 7.5mg Tablet to show results?
A: The effect of Pioz 7.5mg Tablet is gradual and may take a few weeks to show noticeable improvement in blood sugar levels. Unlike some medicines, it does not act immediately. Consistent use along with proper diet and exercise gives the best results. Blood sugar monitoring is important during the first few weeks to check how your body responds. Your doctor may adjust the dose based on your progress. Patience and regular follow-up are important.
Q: Can I take Pioz 7.5mg Tablet with other diabetes medicines?
A: Yes, this tablet is often prescribed along with other diabetes medicines like metformin, sulfonylureas, or insulin. However, combining medicines may increase the risk of side effects such as low blood sugar or fluid retention. Your doctor will decide the right combination and adjust doses as needed. Always inform your doctor about all medicines you take. Do not start or stop any medicine without medical advice, as it may affect blood sugar control.
Q: Is Pioz 7.5mg Tablet safe for long-term use?
A: Yes, many people use this medicine long-term for controlling type 2 diabetes. However, long-term use requires regular monitoring of liver health, heart condition, and weight. Some people may develop side effects like swelling or weight gain over time. Regular follow-ups with your doctor are important to ensure continued safety. If problems arise, your doctor may adjust the dose or switch medicines. With proper monitoring, long-term use can be safe and effective.
Q: What should I do if I accidentally take more Pioz 7.5mg Tablet than prescribed?
A: If you accidentally take more than the prescribed dose, contact your doctor immediately or visit the nearest hospital. Overdose may cause side effects like low blood sugar, swelling, or liver problems. Do not wait for symptoms to appear before seeking help. Carry the medicine strip or prescription with you when visiting the hospital. Prompt medical attention can prevent serious complications. Always keep your medicines stored safely to avoid accidental overdose.
Q: Can Pioz 7.5mg Tablet cause bone problems?
A: Yes, long-term use of Pioglitazone has been linked to an increased risk of bone fractures, especially in women. This happens because of changes in bone density over time. To reduce risk, ensure a healthy diet rich in calcium and vitamin D, and engage in weight-bearing exercises if suitable. If you have a history of fractures, inform your doctor before starting this medicine. Regular monitoring of bone health may be recommended.
References
1.K.D. Tripathi. Insulin, oral hypoglycaemic drugs, and glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 277.
2.Cyrus V. Desouza1,2 and Vijay Shivaswamy1,2. Pioglitazone in the Treatment of Type 2 Diabetes: Safety and Efficacy Review. NIH: National Library of Medicine, National centre for biotechnology information. PMC. PubMed Central. [Revised in 3rd August 2010]. [Accessed on 8th September 2025] 
3.Takeda Pharmaceuticals America, Inc. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 8th September 2025] 
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