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Introduction About PAUSE XT TABLET
PAUSE XT TABLET contains a combination of Tranexamic Acid, Citrus Bioflavonoids, Menadione, and Tribasic Calcium Phosphate which belongs to the group of medicines called Antifibrinolytic agents. It is used to control or reduce excessive bleeding during periods or after surgery.
PAUSE XT TABLET is not recommended for use in patients having active or history of thromboembolic disease (Ex. deep vein thrombosis, pulmonary embolism, or cerebral thrombosis including retinal vein or artery occlusion, thrombogenic valvular disease, thrombogenic cardiac rhythm disease, or hypercoagulopathy).
Before taking PAUSE XT TABLET inform your doctor if you have stomach ulcer, liver disease or blood clotting problems. PAUSE XT TABLET is generally not recommended to use in pregnant women and it should be used with caution in breastfeeding women. PAUSE XT TABLET is not recommended for use in premenarcheal girls and postmenopausal women.
PAUSE XT TABLET should be used with caution in female adolescents below 18 years of age. The most common side effects of PAUSE XT TABLET are headaches, sinus and nasal problems, back pain, stomach pain, pain in the muscles or joints, anemia, and fatigue. Contact your doctor if any of the symptoms worsen or do not improve.
Uses Of PAUSE XT TABLET
- It is used to control or reduce excessive bleeding during periods or after surgery
How PAUSE XT TABLET Works
PAUSE XT TABLET contains a combination of Tranexamic Acid, Citrus Bioflavonoids, Menadione, and Tribasic Calcium Phosphate, where Tranexamic acid is an antifibrinolytic agent that works by forming blood clots normally to reduce bleeding during periods, or after surgery. Tribasic Calcium Phosphate and Citrus Bioflavonoid provide essential nutrients. Menadione is a blood clotting vitamin that controls excessive bleeding.
How to use PAUSE XT TABLET
Take PAUSE XT TABLET as advised by your doctor. Swallow the medicine with a glass of water and try to take it at the same time. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of PAUSE XT TABLET for you depending on your age, disease condition, and body weight.
Side Effects Of PAUSE XT TABLET
Common
- headaches
- sinus and nasal problems
- back pain
- stomach pain
- pain in the muscles or joints
- anemia
- fatigue
Rare
Stop taking PAUSE XT TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (signs include itching and/or skin rash, severe shortness of breath, pain or feeling of heaviness in the chest, coughing up blood, unusual pain or swelling in the arms or legs, and fainting)
- problems with eyesight (like color vision, blood clots in the eye)
How To Manage Side Effects
Headache
Avoid bright lights, drink a lot of water and take enough rest. Consult your doctor if symptoms do not improve.
Stomach Pain
Keep a heat pad on your stomach. Avoid oily and spicy food. Consult your doctor if symptoms do not improve.
Warning & Precautions
Pregnancy
ContraindicatedPAUSE XT TABLET is not recommended for use in pregnant women or women planning to have a baby. Consult your doctor before taking it.
Breastfeeding
Use with CautionPAUSE XT TABLET should be used with caution in breastfeeding women only if clearly needed. Consult your doctor before taking it.
Kidney
Use with CautionPAUSE XT TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take PAUSE XT TABLET if you are allergic to Tranexamic Acid, Citrus Bioflavonoids, Menadione, Tribasic Calcium Phosphate, or any other ingredient of the medicine.
Others
PAUSE XT TABLET is not recommended for use if you have:
- active or history of thromboembolic disease (Ex. deep vein thrombosis, pulmonary embolism, or cerebral thrombosis including retinal vein or artery occlusion, thrombogenic valvular disease, thrombogenic cardiac rhythm disease, or hypercoagulopathy)
Before taking PAUSE XT TABLET, inform your doctor if you have:
- stomach ulcer
- blood clotting problems
Use in pediatrics:
PAUSE XT TABLET is not recommended for use in premenarcheal girls and it should be used with caution in female adolescents below 18 years of age due to lack of safety data.
Use in geriatrics:
PAUSE XT TABLET is not recommended for use in postmenopausal women. Consult your doctor.
Interactions
A. Drug-Drug interactions:
Before taking PAUSE XT TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to help the blood to form clots (Ex. streptokinase)
- medicines used to help break the clots (Ex. warfarin)
- medicines used to manage leukemia (Ex. cyclophosphamide)
- birth control pills or hormonal birth control
Overdosage:
If you or anyone else accidentally takes too much of PAUSE XT TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include nausea, vomiting, dizziness, or visual disturbances.
Synopsis
| Drug | : | Tranexamic Acid, Citrus Bioflavonoids, Menadione, and Tribasic Calcium Phosphate |
| Pharmacological Category | : | Antifibrinolytic agent |
| Therapeutic Indication | : | Control or reduce excessive bleeding during periods or after surgery |
| Dosage Forms | : | Tablet |
More Information
- Keep PAUSE XT TABLET out of reach of children
- Store at room temperature
FAQs About PAUSE XT TABLET
Q: What is PAUSE XT TABLET and why is it given?
A: PAUSE XT TABLET contains a combination of Tranexamic Acid, Citrus Bioflavonoids, Menadione, and Tribasic Calcium Phosphate which belongs to the group of medicines called Antifibrinolytic agents. It is used to control or reduce excessive bleeding during periods or after surgery.
Q: Can PAUSE XT TABLET be used in pregnant and breastfeeding women?
A: PAUSE XT TABLET is generally not recommended for use in pregnant women and it should be used with caution in breastfeeding women. Consult your doctor before taking it.
Q: Is PAUSE XT TABLET safe to use in children?
A: PAUSE XT TABLET is not recommended for use in premenarcheal girls and it should be used with caution in female adolescents below 18 years of age. Your doctor will advise the correct dose and duration of PAUSE XT TABLET depending on your child’s age, disease condition, and body weight.
Q: How to manage if I forget to take a dose of PAUSE XT TABLET?
A: If you forget to take a dose of PAUSE XT TABLET take it as soon as you remember. If it is time for your next dose, then skip the missed dose and take the scheduled dose. Do not take a double dose of PAUSE XT TABLET to compensate for the missed dose.
Q: Can I use PAUSE XT TABLET in patients with kidney disease?
A: PAUSE XT TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor before taking it. Your doctor will advise the correct dose and duration of PAUSE XT TABLET for you depending on your age, disease condition, and body weight.
References
1. KD. Tripathi. Drugs Affecting Blood and Blood Formation. Essentials of medical pharmacology. Seventh edition. 2013. Page – 628.
2. Johnny Cai, Jessica Ribkoff, Sven Olson, Vikram Raghunathan, Hanny Al-Samkari, Thomas G. DeLoughery, and Joseph J. Shatzel. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. European Journal of Hematology. NIH, National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2020 [Accessed on 15th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023891/
3. Anna Ockerman, Thomas Vanassche, Melisa Garip, Christophe Vandenbriele, Matthias M Engelen, Jeroen Martens, Constantinus Politis, Reinhilde Jacobs and Peter Verhamme. Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review. Thrombosis Journal. August 2021 [Accessed on 15th September 2022] https://thrombosisjournal.biomedcentral.com/articles/10.1186/s12959-021-00303-9
4. Trumac Healthcare Ltd. Tranexamic Acid Tribasic Calcium Phosphate Menadione Citrus Bioflavonoid Tablet [Accessed on 15th September 2022] https://www.trumachealthcare.net/tranexamic-acid-tribasic-calcium-phosphate-menadione-citrus-bioflavonoid-tablet-manufacturers-suppliers-in-india-whogmp-third-party-contract-manufacturing/
5. Ferring Pharmaceuticals Inc. US Food and Administration [Revised in October 2013] [Accessed on 15th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022430s004lbl.pdf
6. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Tribasic Calcium Phosphate. [Accessed on 15th September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/ Tribasic Calcium Phosphate
7. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Menadione. [Accessed on 15th September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/ Menadione
8. Bioflavonoids. Drugs.com [Accessed on 15th September 2022] https://www.drugs.com/mtm/bioflavonoids.html
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