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Introduction About PANTOP HP KIT
PANTOP HP KIT is a combination of Clarithromycin, Pantoprazole and Amoxicillin which belongs to the group of medicines called Antibiotics and Antiulcer agents. It is used to eradicate a bacteria called Helicobacter pylori in patients with active chronic gastritis, stomach and intestinal ulcers.
Along management with PANTOP HP KIT your doctor might want you to make some lifestyle changes such as eating less spicy foods. Before starting the management with PANTOP HP KIT your doctor might ask you to take some diagnostic tests to understand the existing condition.
Before taking PANTOP HP KIT inform your doctor if you have liver, kidney or heart disease. PANTOP HP KIT should be taken with caution in patients having fungal infections, glandular fever, problems in urinating, joint pains and due to take Chromogranin A test.
PANTOP HP KIT should be used with caution in pregnant and breast-feeding women. The most common side effects of taking PANTOP HP KIT are nausea, vomiting, diarrhea, vomiting, indigestion and dry mouth. Talk to your doctor if any of these worsen or doesn’t improve.
Uses Of PANTOP HP KIT
- Eradicates Helicobacter pylori in patients with active chronic gastritis, stomach and intestinal ulcers
How PANTOP HP KIT Works
PANTOP HP KIT effectively eradicates H. Pylori and manages ulcers, where Clarithromycin which belongs to a group of medicine called macrolide antibiotics which enters the bacteria and stop its growth thus relieving the infection. Amoxicillin is a penicillin antibiotic which interferes with the important life cycle of the bacteria leading to its destruction. Pantoprazole is a selective proton pump inhibitor, which acts on the cells present in the lining of the stomach and reduces the amount of acid produced in the stomach.
How to use PANTOP HP KIT
Take PANTOP HP KIT as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of PANTOP HP KIT for you depending upon your age, body weight and disease condition.
Side Effects Of PANTOP HP KIT
Common
- headache
- nausea, vomiting
- abdominal pain
- diarrhoea, constipation
- indigestion, heartburn
- dry mouth
- benign polyps in the stomach
- skin rash, discomfort
How To Manage Side Effects
Headache:
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Stomach pain:
Try to rest and relax. Eat and drink slow or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Constipation:
Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. If this does not help, inform your doctor for receiving alternate management for constipation.
Diarrhoea:
Drink lot of fluids such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Inform your doctor if the symptom gets worse.
Dry mouth:
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
PANTOP HP KIT should be used with caution in pregnant women. Consult your doctor before taking it.
Breastfeeding
PANTOP HP KIT should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy or disturbed vision after taking PANTOP HP KIT.
Kidney
PANTOP HP KIT should be used with caution in patients with kidney problems. Consult your doctor before taking PANTOP HP KIT.
Liver
PANTOP HP KIT is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver disease. Consult your doctor before taking PANTOP HP KIT.
Allergy
Do not take PANTOP HP KIT if you are allergic to Clarithromycin, Pantoprazole or Amoxicillin.
Heart Disease
PANTOP HP KIT is not recommended for use in patients having heart rhythm disorders. It should be used with caution in patients with heart problems such as heart failure, an unusually slow heart rate. Consult your doctor before taking PANTOP HP KIT.
Others
Before taking PANTOP HP KIT, inform your doctor if you:
- have fungal infections
- have glandular fever (sore throat, fever, swollen glands and extreme tiredness)
- have problems in urinating
- have joint pain
- are due to have blood test called Chromogranin A test
- have reduced Vitamin B12
- have rashes in areas exposed to sun
Use in Paediatrics:
Your child’s doctor will advise the correct dose and duration of PANTOP HP KIT depending upon the child’s age, weight and disease condition.
Use in Geriatrics:
Your doctor will advise the correct dose and duration of PANTOP HP KIT for you depending upon your age, disease condition and body weight.
Interactions
A. Drug – Drug Interactions:
Before taking PANTOP HP KIT, inform your doctor if you are taking any of the following medicines:
- medicines used for the management of heart problems (Ex. digoxin, disopyramide, quinidine), lower cholesterol (Ex. atorvastatin, rosuvastatin), high blood pressure (Ex. verapamil, amlodipine, diltiazem)
- medicines used for the management of epilepsy (Ex. carbamazepine, valproate, phenobarbital, phenytoin)
- medicines used in patients with breathing difficulties such as asthma (Ex. theophylline)
- sedatives (Ex. triazolam, alprazolam or midazolam)
- medicines used to manage poor circulation (Ex. cilostazol)
- corticosteroid (Ex. methylprednisolone) (used to manage inflammatory condition)
- medicines used for thinning the blood (Ex. warfarin, dabigatran, rivaroxaban, apixaban)
- medicines used to lower blood glucose levels (Ex. nateglinide, pioglitazone, repaglinide, rosiglitazone, gliclazide, glimepiride, insulin)
- medicines used for management of cancer (Ex. vinblastine, erlotinib)
- immune suppressants (Ex. ciclosporin, sirolimus, tacrolimus) (used to manage organ rejection after transplant)
- medicines used in the management of HIV (Ex. ritonavir, efavirenz, etravirine, nevirapine, zidovudine, atazanavir, saquinavir)
- medicines used for management of certain bacterial infections (Ex. rifampicin, rifapentine, rifabutin, lincomycin)
- fluconazole, itraconazole, clindamycin, ketoconazole, itraconazole, posaconazole (used to manage fungal infections)
- medicines used for managing overactive bladder (Ex. tolterodine)
- medicines used for impotence in adult males or for use in pulmonary arterial hypertension (Ex. sildenafil, vardenafil, tadalafil)
- herbal product used to manage depression (Ex. St John’s Wort)
- medicine used to manage rheumatoid arthritis, psoriasis and cancer (Ex. methotrexate)
- medicine used to manage depression and other psychiatric diseases (Ex. fluvoxamine)
- medicines used to manage gout (Ex. probenecid, allopurinol)
Overdosage:
If you or anyone else accidentally take too much of PANTOP HP KIT, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Clarithromycin, Pantoprazole and Amoxicillin |
| Pharmacological Category | : | Macrolides, Proton Pump Inhibitors, Penicillin |
| Therapeutic Indication | : | Eradicates Helicobacter pylori with active chronic gastritis, stomach and intestinal ulcers |
| Dosage Forms | : | Tablet |
More Information
- Keep PANTOP HP KIT out of reach of children
- Store at room temperature
FAQs About PANTOP HP KIT
Q: What is PANTOP HP KIT and why is it given?
A: PANTOP HP KIT is a combination of Clarithromycin, Pantoprazole and Amoxicillin which belongs to the group of medicines called Antibiotics and Antiulcer agents. It is used to eradicate a bacteria called Helicobacter pylori in patients with active chronic gastritis, stomach and intestinal ulcers.
Q: Can PANTOP HP KIT cause diarrhoea?
A: Diarrhoea is a common side effect of taking PANTOP HP KIT. For symptomatic relief, drink lot of fluids such as water, squash or fruit juice to keep yourself hydrated. Do not consume any medicine by yourself without consulting your doctor.
Q: Is PANTOP HP KIT safe for pregnant and breast-feeding women?
A: PANTOP HP KIT should be used with caution in pregnant women and breast-feeding mother. Ask for your doctor’s advice before taking PANTOP HP KIT if you are pregnant, planning to get pregnant and breast-feeding your child.
Q: For how long should I take PANTOP HP KIT?
A: Take PANTOP HP KIT for as long as your doctor has prescribed for you. It depends on your specific condition, age and body weight. Do not stop taking without the doctor’s consultation and do not take it for prolonged periods as well.
Q: What should I tell my doctor before taking PANTOP HP KIT?
A: Before taking PANTOP HP KIT inform your doctor if you have any liver, kidney or heart disease, fungal infections, glandular fever (sore throat, fever, swollen glands and extreme tiredness), problems in urination, joint pain, due to have Chromogranin A test or if you have reduced Vitamin B12.
References
1. KD. Tripathi. Drugs for Peptic Ulcer and GERD, Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 653, 754 & 762
2. Imad M Ghazzawi, Walid A Obeidat, Feras A Zuriekat. Triple therapy with pantoprazole, clarithromycin and amoxicillin for eradication in patients with Helicobacter pylori positive duodenal ulcers. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 2004. [Accessed on 18th June 2022] https://pubmed.ncbi.nlm.nih.gov/15322588/
3. NIH National Library of Medicine, National center for biotechnology information. Clarithromycin. Pubchem. [Accessed on 18th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clarithromycin#section=Mechanism-of-Action
4. Pantoprazole. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Accessed on 18th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Pantoprazole#section=Mechanism-of-Action
5. Amoxicillin. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Accessed on 18th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin#section=Mechanism-of-Action
6. ARISTO Pharmaceuticals Private Limited. Pantop HP Kit (Combipack of Clarithromycin, Pantoprazole & Amoxicillin Tablets. [Revised in February 2022]. [Accessed on 18th June 2022] https://www.aristopharma.co.in/wp-content/uploads/2022/03/Pantop-HP-Kit.pdf
Useful Diagnostic Tests
- Endoscopy
- Complete Blood Count
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