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Aristo Pharmaceuticals Pvt Ltd

PANTOP DSR Capsule 15's

Ulcer/Reflux/Flatule...
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    Introduction About PANTOP DSR CAPSULE

    Pantop DSR Capsule is a dual-action formulation combining Pantoprazole, a proton pump inhibitor and Domperidone, a prokinetic agent. It is helpful for individuals who experience recurring gastric discomfort, acid build-up, post-meal bloating or frequent burping. It is especially beneficial for those with a pattern of acid-related issues that worsen on an empty stomach or after heavy meals. Whether due to irregular meal timings, dietary choices or stress-induced acidity, Pantop DSR is designed to support a more comfortable and regulated digestive experience.   

    Pantoprazole works by reducing the production of excess stomach acid creating a balanced gastric environment, while Domperidone enhances stomach motility, helping move food and gas more efficiently through the digestive tract. It is generally suitable for adults who face frequent episodes of bloating, discomfort after meals, or acid-related unease, especially those with sedentary lifestyles or irregular eating patterns.

    For optimal effectiveness, Pantop DSR Capsule is usually taken once daily before meals, ideally in the morning. It should be swallowed whole with water, without crushing or chewing. Adherence to the recommended timing and dosage, as directed by a healthcare provider, ensures better symptom control. It is important to maintain a gap of at least 30–60 minutes between the capsule and any calcium, iron, or magnesium supplements, as these may interfere with absorption. Avoid consuming alcohol and spicy foods while on this capsule, as these can aggravate stomach acid levels.

    Caution is advised in individuals with liver, kidney, or heart conditions. It is also important to consult a doctor before use in pregnancy or while breastfeeding, as the safety of Domperidone is still under clinical evaluation in such groups. While generally well-tolerated, some users may experience dry mouth, headache, dizziness, or mild gastrointestinal disturbances such as loose stools or constipation. If any unusual or persistent symptoms occur, medical guidance should be sought promptly.

    Uses Of PANTOP DSR CAPSULE

    • Manages acid build-up in the stomach
    • Reduces belching or reflux-like symptoms
    • Improves digestion timing and stomach emptying

    Benefits of PANTOP DSR CAPSULE

    1. Pantop DSR for acid regulation:

    • Pantop DSR Capsule is formulated to regulate stomach acid levels effectively. The Pantoprazole component of the capsule helps manage excessive acid secretion in the stomach, reducing discomfort caused by acid buildup. It works by inhibiting the proton pumps in the stomach which are responsible for acid production
    • When stomach acid is regulated it can alleviate symptoms like heartburn, gastric irritation and acid regurgitation especially after meals. This can lead to a more comfortable digestive experience throughout the day allowing you to enjoy your meals without worrying about discomfort or acid-related symptoms
    • Pantop DSR is typically taken before meals aligning with the body’s natural digestive cycle and supporting effective acid control throughout the day. It benefits are often felt quickly, especially for individuals who experience frequent acidity or acid reflux

    2. Pantop DSR for gastric discomfort and bloating:

    • Pantop DSR Capsule supports individuals experiencing gastric discomfort such as a heavy stomach, bloating or fullness after meals. These symptoms often arise due to slow gastric emptying or excess acid buildup which can interfere with everyday comfort and affect appetite.
    • The capsule contains a combination of Pantoprazole, a proton pump inhibitor that helps manage acid levels in the stomach and Domperidone, a prokinetic agent that aids in enhancing gastric motility. Together they support a more balanced digestive process by helping food and gas move smoothly through the digestive tract
    • By promoting efficient stomach movement and maintaining an optimal environment in the digestive system, Pantop DSR helps in relieving bloating, gas pressure and post-meal heaviness. These benefits can help users feel lighter and more at ease after eating, contributing to better meal tolerance and overall digestive well-being.

    3. Pantop DSR for managing acid reflux symptoms:

    • Acid reflux also known as gastroesophageal reflux occurs when stomach acid moves up into the esophagus, causing irritation and a burning sensation in the chest or throat. Pantop DSR Capsule can be helpful for those experiencing acid reflux-like symptoms, as the Pantoprazole in the capsule reduces stomach acid production managing it from reaching the esophagus
    • The combination of Pantoprazole and Domperidone not only controls acid levels but also helps improve stomach emptying which can manage the stomach from being overly full and reduce the likelihood of reflux. The dual-action formula works both to control excess stomach acid and to encourage smooth digestion which can help reduce regurgitation and discomfort caused by acid reflux
    • By managing acid reflux symptoms, Pantop DSR provides relief from frequent heartburn, a sore throat or discomfort while lying down. Consistent use before meals helps maintain stable acid levels and ensures digestive comfort

    How PANTOP DSR CAPSULE Works

    How Pantop DSR Capsule Supports Gastric Acid Regulation

    The formulation is designed to act at two levels:

    • Regulation of Excess Stomach Acid: The capsule contains a component that helps reduce the volume and acidity of stomach secretions. This contributes to a more neutral internal environment, helping relieve common discomfort associated with hyperacidity
    • Improved Stomach Emptying: By supporting the movement of food through the stomach and into the intestines, this capsule helps reduce the sensation of heaviness, bloating, and fullness which is the common experiences related to delayed gastric emptying

    The delayed-release property ensures that the active ingredients are released only when they reach specific areas of the gastrointestinal tract, helping minimize irritation and maximize their function.

    How to use PANTOP DSR CAPSULE

    1. Recommended Dosage for Pantop DSR Capsule

    • For most individuals, One capsule of Pantop DSR is sufficient to support digestive health and regulate gastric acid levels
    • Duration of use should also be determined by your doctor, based on your individual needs and response to the medication

    2. How and when to take Pantop DSR Capsule

    • Pantop DSR Capsule is best taken once daily, ideally 30–60 minutes before a meal, for optimal effectiveness
    • Take it on an empty stomach: The capsule works most effectively when the stomach is empty, as it supports gastric acid regulation and digestive function
    • Swallow the capsule whole: Do not chew, crush, or break the capsule. This ensures that the active ingredients are released in the right area of your digestive system
    • Drink a full glass of water: This helps in swallowing the capsule and aids in the absorption of the active ingredients
    • Consistency is key: Take your capsule at the same time each day to maintain a consistent level of the medication in your system
    • Avoid taking it with high-fat meals or other substances that might alter its absorption rate

    What if I forgot to take PANTOP DSR CAPSULE

    If you happen to miss a dose of Pantop DSR follow the steps below to maintain consistent use:

    • Take the missed dose as soon as you remember, preferably before a meal if it is still early in the day
    • If it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule
    • Do not take two capsules at the same time to make up for the missed dose, as this may increase the chance of unwanted side effects
    • To avoid missing doses in the future, consider using a reminder app, daily alarm, or pill organizer
    • Maintaining a consistent daily schedule supports the capsule’s effectiveness in promoting digestive balance

    Overdose

    Accidental or intentional overuse of Pantop DSR Capsule may lead to unwanted effects, particularly if taken in amounts exceeding the recommended dosage. While serious effects are uncommon with single extra doses, larger quantities may cause symptoms related to digestive or neurological imbalance.

    Possible signs of overuse may include:

    • drowsiness or dizziness
    • increased heart rate or irregular heartbeat
    • unusual muscle movements or restlessness
    • stomach discomfort or bloating
    • nausea or dry mouth

    Expert Advice:

    • If too many capsules are taken accidentally, seek immediate medical assistance or contact a nearby healthcare facility
    • Do not induce vomiting or attempt self-care without professional supervision
    • Always keep the medication in a safe, child-proof location to avoid accidental access

    Side Effects Of PANTOP DSR CAPSULE

    Common side effects of PANTOP DSR CAPSULE:

    • benign polyps in the stomach
    • dry mouth
    • headache
    • dizziness
    • drowsiness
    • diarrhea
    • constipation
    • stomach pain
    • flatulence

    When to Seek Medical Attention?

    • severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
    • signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
    • severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
    • signs of kidney problem (such as lower back pain, painful urination)
    • signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
    • severe, persistent diarrhea
    • fast or irregular heartbeat, difficulty in breathing, feeling faint
    • fits
    • uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture

    Warning & Precautions

    Pregnancy

    Monitoring required

    PANTOP DSR CAPSULE should be used in pregnant women only if it is considered necessary by the physician.  

    Breastfeeding

    Monitoring required

    PANTOP DSR CAPSULE may pass through breast milk. Therefore, it should be used in breastfeeding women only if it is considered necessary by the physician.  

    Driving and Using Machines

    Use with Caution

    PANTOP DSR CAPSULE does not affect your ability in driving or handling heavy tools or machines. However, do not drive or handle heavy tools or machines if your ability is affected by the medicine.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking PANTOP DSR CAPSULE, as it could aggravate your existing condition.

    Kidney

    Use with Caution

    PANTOP DSR CAPSULE is not recommended for use in patients with moderate or severe liver impairment. It should be used with caution in patients with other mild liver problems.

    Liver

    Consult your doctor

    PANTOP DSR CAPSULE is not recommended for use in patients with moderate or severe liver impairment. It should be used with caution in patients with other mild liver problems.

    Allergy

    Contraindicated

    Do not take PANTOP DSR CAPSULE if you are allergic to Domperidone, Pantoprazole or to any other ingredients of this medicine.

    Heart Disease

    Contraindicated

    PANTOP DSR CAPSULE is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure.

    Use In Pediatrics

    Contraindicated

    PANTOP DSR CAPSULE is not recommended for use in children and adolescents (aged below 18 years).  

    Use In Geriatrics

    Use with Caution

    PANTOP DSR CAPSULE should be used with caution in elderly patients (aged 65 years and above).

    Other Warnings for PANTOP DSR CAPSULE

    Before taking Pantop DSR Capsule inform your doctor if you:

    • have osteoporosis
    • have vitamin B12 deficiency
    • are going to test Chromogranin A level

    Who should not take [GBNKEYWORD

    Who should not take Pantop DSR Capsule

    Pantop DSR Capsule is not recommended for use if you:

    • have bloody stools or bleeding in the gut
    • have blockage or tear in the intestines
    • have severe fluid or electrolyte disturbances
    • have prolactinoma (a non-cancerous tumor of pituitary gland)
    • have low blood potassium or magnesium levels

    Safety Advice

    Expert Safety Advice for Pantop DSR Capsule

    • Use under the supervision of a registered healthcare professional, avoid prolonged self-use.
    • Take the capsule 30–60 minutes before food for optimal digestive support
    • Do not combine with grapefruit juice, alcohol, or high-fat meals to reduce absorption issues
    • Long-term use may require monitoring of magnesium, calcium, or vitamin B12 levels.
    • Caution advised if used alongside medicines that may affect the QT interval (e.g., antifungals, antibiotics)
    • Elderly individuals should use it with care due to higher risk of side effects
    • Do not double the dose if missed, take the next dose at the scheduled time
    • Limit or avoid smoking and alcohol to support better digestive balance
    • Consult a doctor if symptoms persist despite recommended use

    Diet and Lifestyle Advice

    1. Eat Small, Frequent Meals

    • Large meals can strain the digestive system and cause discomfort
    • Opt for smaller portions throughout the day to reduce bloating and maintain digestive ease

    2. Choose Low-Acid, Non-Spicy Foods

    • Reduce intake of acidic foods like tomatoes, citrus fruits, and vinegar
    • Limit spicy, deep-fried, and oily foods that may irritate the stomach lining

    3. Maintain Consistent Meal Timings

    • Irregular eating habits can increase digestive discomfort
    • Try to eat meals at the same time every day to support the natural rhythm of the digestive system

    4. Avoid Lying Down Immediately After Eating

    • Wait at least 1.5 to 2 hours before lying down or going to bed after meals
    • This helps reduce upward movement of stomach contents and supports comfort.

    5. Include Light Physical Activity

    • Gentle activities like walking can support digestive movement
    • Aim for 15–30 minutes of light activity after meals instead of being sedentary

    6. Limit Caffeine and Carbonated Drinks

    • Beverages like coffee, soda, and energy drinks may increase stomach acid
    • Choose non-caffeinated, non-carbonated options like herbal teas or water

    7. Avoid Smoking and Alcohol

    • Smoking and alcohol may aggravate digestive issues and reduce the comfort offered by this capsule
    • If possible, reduce or eliminate usage for better gut health

    8. Manage Stress Levels

    • Stress can trigger digestive sensitivity and discomfort
    • Incorporate calming activities such as deep breathing, meditation to support overall digestive well-being

    9. Stay Hydrated

    • Drink plenty of water throughout the day, especially between meals
    • Avoid drinking large quantities of water during meals, as it may interfere with digestion

    Key Considerations Before Starting Pantop DSR Capsule

    • Before beginning Pantop DSR Capsule, it is important to share your complete medical history with your healthcare provider

    Monitoring Digestive Health While on Pantop DSR

    • While using Pantop DSR, stay attentive to how your body responds, especially in the first few days. Keep track of improvements in symptoms like bloating, fullness, or acidity, as well as any new discomfort
    • If you notice persistent digestive issues or side effects, consult your doctor for guidance. Regular follow-ups help assess the ongoing need and ensure safe, sustained use

    Pantop DSR vs Omez D Capsule

    Criteria

    Pantop DSR Capsule

    Omez D Capsule

    Active Ingredients

    Pantoprazole + Domperidone

    Omeprazole + Domperidone

    Class

    Proton Pump Inhibitor + Prokinetic Agent

    Proton Pump Inhibitor + Prokinetic Agent

    Primary Use

    Supports acid regulation and gastric motility

    Assists in managing acid levels and indigestion

    Onset of Action

    Usually within 1–2 hours

    Typically begins action within 1 hour

    Dosage Timing

    Recommended before meals, usually once daily

    Commonly advised 30–60 minutes before meals

    Stomach Acid Control Duration

    Longer acid suppression duration in some cases

    Moderate acid suppression with standard duration

    Dietary Considerations

    Best taken on an empty stomach

    Best taken before meals for improved absorption

    Drug - Drug interaction

    A. Drug-Drug interactions:

    1. Antifungal Medications (e.g., Ketoconazole, Itraconazole, Posaconazole)

    • Interaction: Reduced absorption of antifungals due to lower gastric acidity caused by Pantoprazole.
    • Management: Take antifungal medicines at least 2 hours before or 4–6 hours after Pantop DSR. Consult a doctor to adjust dosing or consider alternatives

    2. HIV Protease Inhibitors (e.g., Atazanavir, Nelfinavir)

    • Interaction: Pantoprazole may reduce absorption, affecting the efficacy of the antiviral drug
    • Management: Avoid concurrent use unless necessary. Healthcare providers may adjust antiviral regimens or recommend alternatives not impacted by gastric pH

    3. Anticoagulants (e.g., Warfarin, Clopidogrel)

    • Interaction: Pantoprazole and Domperidone may influence blood thinning activity, potentially altering bleeding risk
    • Management: Regular INR monitoring and dose adjustment by a healthcare professional is advised if used together

    4. Antibiotics (e.g., Erythromycin)

    • Interaction: Erythromycin may increase Domperidone levels, potentially raising the risk of QT interval prolongation (cardiac rhythm concern)
    • Management: ECG monitoring may be considered in long-term or high-dose use. Inform your doctor of any dizziness or palpitations

    5. Antidepressants & Antipsychotics (e.g., Fluoxetine, Sertraline, Haloperidol)

    • Interaction: When used with Domperidone, there may be an increased risk of cardiac side effects.
    • Management: Avoid combining with multiple QT-prolonging agents. Regular cardiac monitoring may be advised for sensitive individuals

    6. Heart Rhythm Medicines (e.g., Amiodarone, Quinidine, Dofetilide)

    • Interaction: Concomitant use may enhance the risk of arrhythmias
    • Management: Only use under supervision. Dose adjustments or an ECG before and during use may be recommended

    7. Mineral Supplements (e.g., Calcium, Iron, Magnesium)

    • Interaction: These may interfere with the absorption of Pantoprazole
    • Management: Maintain a gap of 2–4 hours between mineral supplements and Pantop DSR

    Drug - Food interaction

    1. Citrus Juices (Especially Grapefruit Juice)

    • Interaction: Grapefruit juice may inhibit the enzyme CYP3A4, leading to increased levels of Domperidone in the blood. This can heighten the risk of cardiac side effects (e.g., QT prolongation)
    • Management: Avoid grapefruit and related citrus juices while using Pantop DSR. Opt for water or non-citrus beverages when taking the capsule

    3. Caffeine-Rich Beverages (e.g., Coffee, Energy Drinks)

    • Interaction: Excess caffeine may increase gastric acid secretion, which can reduce the capsule’s effectiveness in acid balance. It may also aggravate gastric symptoms like bloating or reflux-like discomfort
    • Management: Moderate caffeine intake and avoid taking the capsule with caffeinated drinks. Water is preferred for swallowing the capsule

    4. Calcium, Iron, or Magnesium-Rich Foods

    • Interaction: These minerals can interfere with the absorption of Pantoprazole, especially when consumed close to medication timing
    • Management: Maintain a gap of at least 2 hours between such mineral-rich meals or supplements and Pantop DSR for optimal absorption

    5. Spicy and Acidic Foods

    • Interaction: Spicy, acidic, or fried foods may exacerbate gastric irritation, countering the intended soothing effect of Pantop DSR
    • Management: Choose a bland, low-acid diet while on Pantop DSR to support digestive comfort and reduce recurrence of bloating or acidity

    Synopsis

    Drug :   Domperidone, Pantoprazole
    Pharmacological Category :   Dopamine D2 antagonists, Proton-pump inhibitors
    Therapeutic Indication :   Peptic ulcer, GERD, Reflux esophagitis   
    Dosage Forms :   Tablet, Capsule

    More Information

    Storage

    • Store Pantop DSR Capsule at room temperature, typically between 20-25°C
    • Keep this medication away from direct sunlight, heat sources and humidity to maintain its effectiveness

    FAQs About PANTOP DSR CAPSULE

    Q: Is Pantop DSR the same as an antacid?

    A: No. Pantop DSR is not a simple antacid. It works at a deeper level by reducing the actual acid production. Antacids only neutralize acid temporarily. Pantop DSR offers longer-lasting control over stomach acid.

    Q: How does Pantop DSR Capsule help with acidity?

    A: It contains two components namely Pantoprazole and Domperidone that work together. Pantoprazole reduces acid production in the stomach. Domperidone helps move food through the digestive system more effectively. Together, they relieve acid-related discomfort.

    Q: Can I use Pantop DSR for gas and bloating?

    A: Yes, it can help relieve gas and bloating caused by acid-related digestive issues. Domperidone improves gut movement and reduces gas build-up. This makes digestion smoother and reduces discomfort. Always consult your doctor before use.

    Q: How fast does Pantop DSR start to work?

    A: You may start feeling relief within a few hours of taking the first dose. However, full benefits may take a couple of days. Consistent use is key for long-term improvement. Take it exactly as advised by your doctor.

    Q: Is Pantop DSR Capsule suitable for long-term use?

    A: It can be safe under medical supervision, but long-term use may affect nutrient absorption. Your doctor may monitor calcium, magnesium, and vitamin B12 levels. Do not stop or continue the medicine without guidance. Regular checkups are helpful.

    Q: How many times a day should I take Pantop DSR?

    A: Usually, it is taken once daily, but your doctor may adjust this. Do not change the dose or frequency without medical advice. Overuse can increase the risk of side effects. Stick to the recommended plan.

    Q: Can I take Pantop DSR at night?

    A: It is usually best taken in the morning before meals. However, some doctors may prescribe it at night based on your symptoms. Always follow the timing advised specifically for you. Do not change your routine on your own.

    Q: Can children take Pantop DSR Capsule?

    A: This medication is generally not recommended for children without specific medical advice. Consult a pediatrician for appropriate treatment options.

    Q: Is Pantop DSR Capsule habit-forming?

    A: No, it is not known to be habit-forming. However, it should be used as prescribed by your doctor.

    Q: Can Pantop DSR cure ulcers?

    A:It helps reduce acid, giving ulcers a chance to heal. However, additional management may be required depending on the cause. Follow-up with your doctor is key. Do not rely on it as a cure-all.

    Q: What should I do if I get diarrhea after taking Pantop DSR?

    A: Mild diarrhea may occur as your body adjusts. Stay hydrated and inform your doctor if it continues. Severe diarrhea could indicate a more serious issue.

    Q: Can stress make my acidity worse?

    A: Yes, stress is a known trigger for acid reflux and bloating. Try relaxation techniques like deep breathing. Pantop DSR works better with lifestyle management.

    Q: Can I switch brands of Pantop DSR?

    A: Only do so with your doctor’s guidance. Different brands may have slight formulation differences. Always follow medical advice when switching.

    Q: How does Pantop DSR improve digestion?

    A: Pantop DSR improves digestion by combining two active ingredients that work together to reduce excess stomach acid and enhance stomach motility. One component lowers acid secretion, creating a more balanced digestive environment. The other supports smoother movement of food through the stomach and intestines. This dual action helps ease discomfort like bloating and fullness.

    User Feedback

    1. Cipla Ltd. NEW PANTOSEC D SR Capsules (Pantoprazole Gastro-resistant + Domperidone Prolonged Release Capsules IP). Ciplamed.com. [Revised in April 2020] [Accessed on 10th May 2025] 

    2. Nur Fathurah Zamani, Afifah Sjamun Sjahid, Tuan Hairulnizam Tuan Kamauzaman, Yeong Yeh Lee and Md Asiful Islam. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Journal of Clinical Medicine. August 2022. [Accessed on 10th May 2025] 

    3. Pantoprazole. StatPearls. [Revised in 10 July 2023] [Accessed on 10th May 2025].

    4. Leeford Healthcare Ltd. Pantafol-D. [Accessed on 10th May 2025]

    5. Hetero Healthcare Ltd. Pantin RD Tablet. [Accessed on 10th May 2025]

    Author Details

    Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 13 May 2025 | 09:57 AM(IST)
    Lab updated