Pantakind DSR Capsule 10'S

Introduction About PANTAKIND DSR CAPSULE

Pantakind DSR Capsule combines Pantoprazole and Domperidone. It is often advised to support digestive comfort in individuals experiencing symptoms such as acidity, gas, or a heavy stomach (peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis). It works by reducing stomach acid and helping with gut motility.

It should be taken at least 15-30 minutes before meals. Your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects. Before taking PANTAKIND DSR CAPSULE inform your doctor if you have any liver, kidney or heart problems, blockage or tears in the gut or have weak bones.

PANTAKIND DSR CAPSULE is not recommended for use in patients bleeding from the gut. Consult your doctor before taking PANTAKIND DSR CAPSULE if you are pregnant or breastfeeding. Common side effects are dryness of mouth, constipation and flatulence.

Inform your doctor immediately if you experience any signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat).

Key Composition

• Pantoprazole (Proton Pump Inhibitor)
• Domperidone (Prokinetic agent)

Uses Of PANTAKIND DSR CAPSULE

Manages:

• Peptic ulcer
• Gastrointestinal Reflux disease (GERD)
• Reflux esophagitis (inflammation of the esophagus)
• Nausea and Vomiting
• Acidity, Heartburn
• Signs of indigestion (such as burping, bloating)

Benefits of PANTAKIND DSR CAPSULE

• Dual Action Support for Digestive Comfort: Pantakind DSR combines two active ingredients—pantoprazole and domperidone—that work together to support overall digestive system function.
• Helps Maintain Stomach Acid Balance: Pantoprazole is a type of acid suppressant that supports a balanced pH in the stomach by minimizing excess acid production.
• Supports Timely Gastric Emptying: Domperidone helps the stomach empty food more efficiently, promoting smoother digestion and minimizing the sensation of heaviness after meals.
• May Ease Bloating and Fullness Sensation: The formulation may assist in reducing feelings of bloating, belching, or post-meal fullness that are sometimes experienced with delayed gastric emptying.
• Formulated for Use on an Empty Stomach: Pantakind DSR is usually recommended to be taken before meals, making it well-suited to align with the body’s natural digestive rhythm.
• Available in Delayed-Release Capsule Form: Its specialized delayed-release design ensures that the ingredients are released gradually, enhancing absorption and effectiveness.

How PANTAKIND DSR CAPSULE Works

Overview of the Dual-Action Mechanism

Pantakind DSR Capsule combines two active ingredients—Pantoprazole (a proton pump inhibitor) and Domperidone (a prokinetic agent). Together, they offer complementary actions in supporting digestive balance.

Role of Pantoprazole: Acid Regulation

Pantoprazole acts by selectively inhibiting the H?/K? ATPase enzyme system located in the gastric parietal cells. This action leads to a controlled reduction in gastric acid secretion, helping maintain a balanced pH environment in the stomach.

Role of Domperidone: Gastric Motility Support

Domperidone primarily works as a dopamine D2 receptor antagonist in the upper digestive tract. By enhancing the movement of food through the stomach and intestines, it supports better gastric emptying and reduces the sensation of bloating and fullness.

How the Combination Supports Digestive Health

While Pantoprazole works on controlling acid production, Domperidone facilitates the smooth passage of food through the digestive tract. The combination helps reduce acid-related discomfort and may support individuals who experience post-meal heaviness or reflux-related symptoms.

How to use PANTAKIND DSR CAPSULE

How Should You Take Pantakind DSR Capsule?

• Take PANTAKIND DSR CAPSULE 15-30 minutes before meals or as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking PANTAKIND DSR CAPSULE unless your doctor advice you to stop

Best Time to Take Pantakind DSR – Morning or Night?

Pantakind DSR is usually advised to be taken once daily in the morning, preferably on an empty stomach. Taking it before breakfast may help align the capsule’s acid-suppressing action with peak acid production.

Should Pantakind DSR Be Taken With or Without Food?

It is generally recommended to take Pantakind DSR before meals, ideally 30 to 60 minutes prior to breakfast. This ensures optimal absorption and activity of both pantoprazole and domperidone.

Dosage Guidelines for Adults and Elderly Individuals

• For adults: One capsule daily is commonly advised before meals. 
• For elderly users: Caution may be exercised in individuals with kidney or liver conditions; consult a healthcare provider for personalized dosage.

What if I forgot to take PANTAKIND DSR CAPSULE

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular timing. Avoid double-dosing.

Overdose

• Contact your doctor immediately or go to a hospital straight away in case of overdosage.
• Symptoms include sleepiness, confusion, uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture.

Side Effects Of PANTAKIND DSR CAPSULE

Common side effects of PANTAKIND DSR CAPSULE:

• benign polyps in the stomach
• dry mouth
• headache, dizziness, drowsiness
• diarrhea, constipation, stomach pain, flatulence

Rare but Reported Side Effects – What You Should Know:

• severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• signs of kidney problem (such as lower back pain, painful urination)
• severe, persistent diarrhea
• fast or irregular heartbeat, difficulty in breathing, feeling faint
• fits
• uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture

Is Pantakind DSR Safe for Long-Term Use?

Long-term use of Pantakind DSR should be evaluated under medical supervision, especially in individuals with existing kidney, liver, or heart-related concerns. Periodic monitoring may be suggested for people using this capsule beyond a few weeks.

Considerations for Extended Use:

• Long-term acid suppression may affect calcium or magnesium levels in rare cases
• Domperidone use over extended periods may be associated with cardiac rhythm effects, particularly in elderly users
• Nutrient absorption (e.g., Vitamin B12) may be influenced by prolonged reduction in stomach acid

Always follow the duration and dosage as advised by your healthcare provider. Do not self-extend usage without medical consultation.

Warning & Precautions

Pregnancy

Monitoring required

PANTAKIND DSR CAPSULE should be used in pregnant women only if it is considered necessary by the physician.  Animal studies conducted on pantoprazole and domperidone have not shown direct harmful effects on fetal development at normal dose levels. However, in human studies, the available safety data is limited and inconclusive, especially in early pregnancy.

Breastfeeding

Monitoring required

Pantoprazole is secreted in small amounts into breast milk, but the risk to the nursing infant is considered low, especially with short-term use. Domperidone, though present in breast milk in trace quantities, is associated with potential concerns for cardiac rhythm effects in newborns, especially in high doses. Hence, use during lactation requires cautious assessment, and should ideally be limited to situations where the expected benefit outweighs potential infant exposure.

Driving and Using Machines

Use with Caution

PANTAKIND DSR CAPSULE does not affect your ability in driving or handling heavy tools or machines. But, do not drive or handle heavy tools or machines if your ability is affected by the medicine.

Alcohol

Consult your doctor

Avoid alcohol consumption while taking PANTAKIND DSR CAPSULE, as it could aggravate your existing condition.

Kidney

Use with Caution

PANTAKIND DSR CAPSULE should be used cautiously  in patients with kidney problems.  

Liver

Consult your doctor

PANTAKIND DSR CAPSULE is not recommended for use in patients with moderate or severe liver impairment. It should be used cautiously in patients with other mild liver problems.

Allergy

Contraindicated

Do not take PANTAKIND DSR CAPSULE if you are allergic to Domperidone, Pantoprazole or to any other ingredients of this medicine.

Heart Disease

Contraindicated

PANTAKIND DSR CAPSULE is not recommended for use in patients with heart problems like prolongation of QT interval or congestive heart failure.  

Use In Pediatrics

Contraindicated

PANTAKIND DSR CAPSULE is not recommended for use in children and adolescents (aged below 18 years).  

Use In Geriatrics

Use with Caution

PANTAKIND DSR CAPSULE should be cautiously in elderly patients (aged 65 years and above).

Other Warnings for PANTAKIND DSR CAPSULE

Before taking PANTAKIND DSR CAPSULE inform your doctor if you:

• have osteoporosis
• have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• are going to test Chromogranin A level

Who should not take PANTAKIND DSR CAPSULE

PANTAKIND DSR CAPSULE is not recommended for use if you:

• have bloody stools or bleeding in the gut
• have blockage or tear in the intestines
• have severe fluid or electrolyte disturbances
• have prolactinoma (a non-cancerous tumor of pituitary gland)
• have low blood potassium or magnesium levels

Diet and Lifestyle Advice

Foods to Include

• Eat Small, Frequent Meals: Helps reduce acid build-up and supports smoother digestion.
• Include Alkaline Foods: Oatmeal, bananas, melons, and green leafy vegetables are generally gentle on the stomach.
• Hydration Matters: Sip water throughout the day; avoid drinking large quantities during meals.
• Ginger & Fennel Water: Traditionally used to manage bloating and support gut comfort.

Foods to Limit or Avoid

• Spicy & Oily Foods: May increase gastric irritation or discomfort.
• Caffeinated Drinks: Coffee, energy drinks, and strong tea may aggravate acidity in some individuals.
• Citrus Fruits & Juices: Orange, lemon, and tomato products may trigger symptoms in sensitive individuals.
• Processed and Packaged Foods: Can slow digestion and increase gastric pressure.

Lifestyle Habits That Support Digestive Wellness

• Elevate Your Head While Sleeping: Helps prevent nighttime acid backflow.
• Wait Before Lying Down After Meals: A 2–3 hour gap is typically advised after eating.
• Practice Mindful Eating: Chew slowly and avoid overeating, especially during dinner.
• Wear Loose-Fitting Clothing: Tight waistbands may increase abdominal pressure.
• Stay Active: Light walks post-meals can promote better digestion.
• Manage Stress: Relaxation techniques like breathing exercises, yoga, or journaling may help reduce gut discomfort linked to stress.

Interactions

Medicines That May Interact With Pantakind DSR

Pantakind DSR contains Pantoprazole (a proton pump inhibitor) and Domperidone (a prokinetic). These may interact with other medicines in ways that can affect how they work or increase the risk of side effects.

Common Interaction Warnings Include:

• Antifungal drugs like ketoconazole, itraconazole (absorption may be reduced)
• Antiretrovirals (e.g., atazanavir, rilpivirine) – may lose effectiveness with acid suppression
• Blood thinners like warfarin – requires monitoring of bleeding parameters
• Heart medications (e.g., amiodarone, quinidine) – possible rhythm-related concerns with domperidone
• Certain antibiotics like erythromycin or clarithromycin – may enhance domperidone-related risks
• Antipsychotics or antidepressants – potential additive CNS effects

Synopsis

More Information

Comparison of Pantakind DSR Capsule with Similar Medicines

Did you know

• The combination of Pantoprazole and Domperidone is often prescribed together because one supports acid regulation while the other assists with digestive motility
• Domperidone is not absorbed easily in the brain, which means it typically causes fewer central nervous side effects compared to some older medicines.
• Pantakind DSR uses a dual-layer capsule format – one layer releases Pantoprazole in the intestine, while the other provides Domperidone action in the stomach
• It is generally advised to take this capsule before meals because food can affect the absorption of the ingredients
• Medicines like Pantakind DSR are often part of broader lifestyle advice that includes diet adjustments, posture habits, and eating timings.
• Domperidone is listed in WHO’s list of essential medicines under certain use cases, highlighting its role in specific digestive support needs
• Long-term use of acid-regulating agents may require monitoring of magnesium and vitamin B12 levels – ask your healthcare provider if you need tests.

FAQs About PANTAKIND DSR CAPSULE

References

1. KD. Tripathi. Antiemetic, Prokinetic and Digestant drugs & Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Seventh edition. 2013. Page – 666 & 653.

2. Nur Fathurah Zamani, Afifah Sjamun Sjahid, Tuan Hairulnizam Tuan Kamauzaman, Yeong Yeh Lee and Md Asiful Islam. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Journal of Clinical Medicine. August 2022. [Accessed on 31st July 2025] 

3. Panacea Biotec Limited. OD-PEP-D CAPSULES. [Revised in July 2019]. [Accessed on 31st July 2025] 

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2021]. [Accessed on 31st July 2025] 

5. Takeda GmbH. Electronic Medicines Compendium (EMC). [Revised in April 2022]. [Accessed on 31st July 2025] 

6. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in November 2021]. [Accessed on 31st July 2025] 

7. Leeford Healthcare Ltd. Pantafol-D. [Accessed on 31st July 2025] 

8. Hetero Healthcare Ltd. Pantin RD Tablet. [Accessed on 31st July 2025] 

9. Central Drugs Standard Control Organization. Pantoprazole+Domperidone SR. [Revised in December 2004] [Accessed on 31st July 2025] 

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Stool Complete Analysis
• Upper GI endoscopy
• H. pylori breath test
• Liver function test
• Kidney  function tests

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 07 Aug 2025 | 12:17 PM(IST)