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Introduction About PACROMA XL CREAM
PACROMA XL CREAM is used to manage atopic dermatitis (inflammation of the skin). It is also used to manage signs and symptoms of mild or moderate eczema (e.g. redness and itch) in children aged 3 months to 17 years and adults. PACROMA XL CREAM contains Pimecrolimus which belongs to the group of medicines called Non-steroidal immunosuppressant which works in the cells in the skin that cause the inflammation and characteristic redness and itching of eczema.
PACROMA XL CREAM is not recommended for use in other skin conditions and skin affected by an active viral infection such as cold sores (herpes simplex) or chicken pox. Avoid exposure to sunlight while using PACROMA XL CREAM. This medicine is generally not recommended for use among pregnant and breastfeeding women.
The most common side effects of using PACROMA XL CREAM are feeling of warmth and burning sensation at the application site, irritation, itching, and reddening of the skin where the cream has been applied and skin infections (folliculitis). Consult your doctor if any of the side effect worsens.
Uses Of PACROMA XL CREAM
- Used to manage atopic dermatitis (eczema)
How PACROMA XL CREAM Works
PACROMA XL CREAM contains Pimecrolimus which is a calcineurin inhibitor works by blocking calcineurin (a protein in our bodies that helps to activate the immune system). By blocking the immune response it lessens the inflammation which is caused by eczema.
How to use PACROMA XL CREAM
Always apply PACROMA XL CREAM as directed by your physician. It is for external use only. Wash and dry your hands before applying. Apply a thin layer of PACROMA XL CREAM to the affected area and rub it gently and fully. Avoid applying this medicine around nose, eyes or mouth. Do not cover the manageed areas of skin with dressings, bandages, and wraps. Do not bath or shower right after applying the cream as this could wash your cream off.
Side Effects Of PACROMA XL CREAM
Common
- warm feeling at the application site
- discomfort, burning sensation, stinging, soreness, irritation, itching or reddening of the skin (of the particular area where the medicine is applied)
- skin infections (folliculitis)
Uncommon
- skin infections (such as impetigo, cold sores, shingles, herpes simplex dermatitis, molluscum contagiosum, warts and furuncles
- rash, pain, prickling sensation, slight scaling of the skin, dryness, swelling and worsening of eczema symptoms (application site reactions)
Rare
- changes in skin color (darker or lighter than the surrounding skin)
Stop applying PACROMA XL CREAM and contact your doctor immediately if you experience any of the following side effects:
- angioedema (hives, itching, red marks on the hands, feet and throat, swelling of the throat and tongue, swelling around the eyes and lips and difficulty breathing and swallowing)
Warning & Precautions
Pregnancy
ContraindicatedPACROMA XL CREAM is not recommended for use in pregnant women. Consult your doctor before using the medicine.
Breastfeeding
ContraindicatedPACROMA XL CREAM is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Consult your doctor before using it.
Driving and Using Machines
Consult your doctorPACROMA XL CREAM has no known effect on the ability to drive or use machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while applying PACROMA XL CREAM as it may cause flushing, rash, burning or itching sensation or swelling. Consult your doctor before using the medicine.
Allergy
ContraindicatedDo not apply PACROMA XL CREAM if you are allergic to Pimecrolimus or any of the other ingredients of this medicine.
Use In Pediatrics
ContraindicatedPACROMA XL CREAM is not recommended for use in children (under 3 months of age). Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionPACROMA XL CREAM should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before applying PACROMA XL CREAM.
Others
PACROMA XL CREAM is not recommended for use if you:
- have active viral infection (cold sores or chicken pox)
Before applying PACROMA XL CREAM, inform your doctor if you have:
- weakened immune system (immunocompromised)
- erythroderma (redness in almost the entire body) or a skin condition called netherton syndrome
- skin malignancies (tumors) or swollen lymph nodes
Interactions
A. Drug-Drug interactions:
Before applying PACROMA XL CREAM, inform your doctor if you are taking or applying any of the following medicines:
- Immunomodulators (Ex. azathioprine or cyclosporin)
- Antibiotics (Ex. erythromycin)
- Anti-fungal agents (Ex. itraconazole, ketoconazole, fluconazole)
- Calcium channel blockers (Ex. diltiazem, nifedipine)
- H2 blockers (Ex. Cimetidine)
Overdosage:
If you or anyone else applied too much of PACROMA XL CREAM or accidentally swallowed the medicine, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Pimecrolimus |
| Pharmacological Category | : | Immunosuppressant |
| Therapeutic Indication | : | Atopic dermatitis (eczema) |
| Dosage Forms | : | Cream, Lotion |
More Information
Storage
- Keep PACROMA XL CREAM out of the sight and reach of children.
- Store PACROMA XL CREAM below 25°C.
FAQs About PACROMA XL CREAM
Q: What is PACROMA XL CREAM used for?
A: PACROMA XL CREAM is used to manage atopic dermatitis (inflammation of the skin). It is also used to manage signs and symptoms of mild or moderate eczema (e.g. redness and itch) in children aged 3 months to 17 years and adults.
Q: Can I consume alcohol while using PACROMA XL CREAM?
A: Avoid consumption of alcohol while applying PACROMA XL CREAM as it may cause flushing, rash, burning or itching sensation or swelling. Consult your doctor before using the medicine.
Q: Is PACROMA XL CREAM safe to use in breast-feeding women?
A: PACROMA XL CREAM is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Consult your doctor before using the medicine.
Q: When to avoid using PACROMA XL CREAM?
A: PACROMA XL CREAM is not recommended for use if your skin is affected by an active viral infection such as cold sores (herpes simplex) or chickenpox. It is not recommended for use in patients who are allergic to Pimecrolimus.
Q: What are the common side effects seen with PACROMA XL CREAM?
A: The most common side effects of using PACROMA XL CREAM are feeling of warmth and burning sensation at the application site, irritation, itching and reddening of the skin where the cream has been applied and skin infections (folliculitis). Consult your doctor if any of the side effect worsens.
Q: Can I buy PACROMA XL CREAM online?
A: If you wish to buy PACROMA XL CREAM in Netmeds, you need a prescription from a Registered Medical Practitioner. Netmeds has made buying online medicines easier for consumers and is one of India's leading Online Pharmacy.
Q: How many times a day can I use PACROMA XL CREAM?
A: Apply a thin layer of PACROMA XL CREAM, only to the affected skin areas, two times each day or as directed by your doctor.
Q: Can I apply moisturizer after PACROMA XL CREAM?
A: The manageed skin areas should not be bandaged or covered after the medicine is applied. You may use moisturizers to lessen dryness of the affected areas of your skin. Apply the moisturizer after using this medicine. Consult your doctor for advice.
References
1. Matthew J. Sewell, Craig N. Burkhart, and Dean S. Morrell. Dermatological Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 1271-1296.
2. Grace K. Kim, and James Del Rosso. Uses of Pimecrolimus Cream. The Journal of Clinical and Aesthetic Dermatology. February 2013. [Accessed on May 10th 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579486/
3. Novartis Pharmaceuticals. Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in March 2011] [Accessed on May 10th 2024] https://clinicaltrials.gov/ct2/show/NCT00124709
4. Mylan Products Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on May 10th 2024] https://www.medicines.org.uk/emc/files/pil.4966.pdf
5. Biocon Biologics India Limited. Pimecrolimus solution 1% w/v (Picon lotion). Biocon.com. [Revised in August 2019] [Accessed on May 10th 2024] https://www.biocon.com/docs/domestic-marketpi/immuno/PICON%20LOTION%20PI.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Platelet Count/ Thrombocyte Count
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