Pacimol MF 250mg Suspension 60ml

Introduction About PACIMOL MF SUSPENSION

Pacimol MF 250mg Suspension is a commonly used combination medicine that contains Paracetamol and Mefenamic Acid. It belongs to the group of analgesic and anti-inflammatory agents. This suspension is often considered in situations where individuals experience pain along with fever or inflammation. It works by reducing pain signals and controlling inflammation, helping improve overall comfort during episodes of discomfort.

Pacimol MF 250mg Suspension is frequently recommended for managing mild to moderate pain such as toothache, body pain, headache, or fever-related discomfort. It may also be used in conditions involving inflammation where both pain relief and fever control are required. The suspension form makes it easier to administer, especially in children, as per medical guidance.

This medicine is usually given in measured doses using a dosing cup or spoon, preferably after food to reduce the chances of stomach irritation. Patients are advised to follow a fixed dosing schedule and avoid exceeding the recommended dose. Proper hydration and adherence to instructions help ensure better tolerance and effectiveness.

Use during pregnancy and breastfeeding should be guided by a healthcare professional. Common side effects may include nausea, stomach discomfort, or mild dizziness. If symptoms persist or worsen, medical advice should be sought. This medicine is generally part of short-term care, supported by rest, hydration, and balanced nutrition.

Uses Of PACIMOL MF SUSPENSION

•  Helps relieve mild to moderate pain such as headache, toothache, and body pain
•  Supports reduction of fever and inflammation

Benefits of PACIMOL MF SUSPENSION

Pacimol MF for Pain Relief

Pacimol MF Suspension may be advised to ease different types of pain by acting on pain signals in the body. It helps reduce discomfort, making daily activities more manageable. It is often included in short-term care plans where quick relief from pain is needed.

Pacimol MF for Fever

This medicine supports lowering elevated body temperature by acting on the temperature-regulating centre in the brain. It helps improve comfort during fever and may assist in restoring normal body temperature when used as directed.

Pacimol MF for Inflammation

Pacimol MF helps reduce inflammation-related discomfort by blocking substances responsible for swelling and pain. This can improve mobility and reduce tenderness in affected areas.

How PACIMOL MF SUSPENSION Works

Pacimol MF Mechanism of Action

Pacimol MF contains Paracetamol and Mefenamic Acid. Paracetamol works by reducing pain and fever through its action on brain chemicals. Mefenamic Acid, a non-steroidal anti-inflammatory drug (NSAID), reduces inflammation by blocking prostaglandins, which are responsible for pain and swelling.

Role in Pain and Fever Control

This combination provides dual action relieving pain while also addressing inflammation and fever. It helps improve overall comfort and supports faster recovery from discomfort.

Effect on Inflammation and Body Response

By reducing inflammatory mediators, Pacimol MF helps calm tissue irritation and swelling. This leads to improved physical comfort and reduced sensitivity in affected areas.

How to use PACIMOL MF SUSPENSION

How to Take Pacimol MF Suspension

•  Take exactly as advised by your doctor
•  Shake the bottle well before use
•  Measure the dose using a proper measuring cup or spoon
•  Take it after food to reduce stomach discomfort
•  Do not exceed the prescribed dose

What if I forgot to take PACIMOL MF SUSPENSION

•  Take the missed dose as soon as you remember
•  Skip if it’s close to the next dose
•  Do not double the dose
•  Follow your regular schedule
•  Use reminders to avoid missed doses

Overdose

If more than the recommended dose is taken, consult a doctor immediately. Overdose may lead to symptoms such as nausea, vomiting, stomach pain, or liver-related concerns.

Side Effects Of PACIMOL MF SUSPENSION

How To Manage Side Effects

Warning & Precautions

Other Warnings for PACIMOL MF SUSPENSION

Before taking Pacimol MF Suspension, inform your doctor if you have

• hyperthyroidism
• closed-angle glaucoma
• fluid retention or edema
• poor general health
• anaemia
• intolerance to fructose or other sugars
• bleeding disorder
• major operation
• connective tissue disorder (Ex. Systemic Lupus Erythematous)
• epilepsy
• dehydration
• diabetes
• high cholesterol levels
• smoking history

Who should not take PACIMOL MF SUSPENSION

Pacimol MF Suspension is not recommended for use if you

• peptic ulcer, bleeding in the stomach, severe gastritis, active ulceration/bleeding, or chronic inflammation of the upper or lower gastrointestinal (GI) tract
• have inflammatory bowel disease (Ex. ulcerative colitis, Crohn's disease)
• have obstructive uropathy
• had coronary artery bypass graft (CABG) surgery

Safety Advice

• Use only as prescribed: Follow the exact dose and duration advised by your doctor. Do not exceed the recommended dose, as it may increase the risk of side effects, especially related to the liver and stomach.
•  Avoid combining with other pain relievers: Do not take additional medicines containing Paracetamol or NSAIDs unless advised, as this may increase the risk of overdose or stomach irritation.
•  Take after food: Prefer taking the suspension after meals to help reduce the chances of stomach discomfort or irritation.
•  Stay hydrated: Drink enough fluids throughout the day to support overall body balance and reduce side effects like dizziness or dryness.
•  Use caution in certain health conditions: Inform your doctor if you have liver, kidney, heart, or stomach-related problems before starting this medicine.
•  Watch for allergic reactions: Seek medical attention if you notice symptoms like rash, itching, swelling, or breathing difficulty.
•  Do not use long-term without advice: This medicine is generally meant for short-term use. Prolonged use should only be under medical supervision.

Diet and Lifestyle Advice

• Take light, balanced meals: Prefer simple foods like rice, dal, fruits, and vegetables. Avoid oily, spicy, or heavy meals that may increase stomach discomfort.
• Stay well-hydrated: Drink plenty of water, soups, or oral fluids to support recovery and help reduce side effects like dizziness or nausea.
• Limit caffeine intake: Reduce tea, coffee, and cola, as they may worsen stomach irritation or restlessness.
•  Eat fibre-rich foods: Include fruits, vegetables, and whole grains to support digestion and prevent constipation.
•  Take adequate rest: Proper sleep and rest help the body recover faster from pain or fever-related discomfort.
•  Maintain a regular meal schedule: Eating at consistent times can help reduce gastric irritation and improve tolerance to the medicine.
•  Engage in light activity:  Gentle movements like walking can support circulation and overall well-being but avoid strenuous activity during discomfort.
• Avoid skipping meals: Taking the medicine on an empty stomach may increase the chances of stomach upset.
•  Monitor your body’s response: If certain foods worsen symptoms like nausea or discomfort, avoid them and choose easily digestible options.

1. Pacimol MF 250mg Suspension vs Ibuprofen - Managing Pain and Inflammation

Feature / Aspect	Pacimol MF Suspension	Ibuprofen
Active Ingredients	Paracetamol + Mefenamic Acid	Ibuprofen
Drug Class	Combination of analgesic + NSAID	NSAID (Non-Steroidal Anti-Inflammatory Drug)
Mechanism of Action	Paracetamol reduces pain & fever; Mefenamic Acid reduces inflammation by blocking prostaglandins	Blocks prostaglandins to reduce pain, fever, and inflammation
Pain Relief	Effective for mild to moderate pain with added benefit of combination therapy	Effective for mild to moderate pain
Anti-inflammatory Effect	Present (due to Mefenamic Acid)	Strong anti-inflammatory effect
Fever Reduction	Yes (due to Paracetamol)	Yes
Onset of Action	Usually within 30–60 minutes	Usually within 20–60 minutes
Use in Children	Commonly used with doctor’s guidance	Widely used with proper dosing
Stomach Tolerance	May cause irritation due to NSAID component	May also cause stomach irritation, especially with long use
Risk of Liver Effects	Higher risk if overdosed (due to Paracetamol)	Lower compared to combination, but caution still needed
Dosing Frequency	As prescribed (often 2–3 times daily)	Usually every 6–8 hours depending on need
Best Suited For	Pain with fever and inflammation requiring combination support	Pain and inflammation, especially where strong anti-inflammatory action is needed

Drug - Drug interaction

1. Other NSAIDs (e.g., Ibuprofen, Aspirin, Diclofenac)

• Interaction: Taking Pacimol MF with other NSAIDs may increase the risk of stomach irritation, ulcers, and bleeding.
• Management: Avoid combining multiple painkillers unless prescribed. If necessary, your doctor may adjust doses and monitor for gastric side effects.

2. Blood Thinners (e.g., Warfarin, Heparin)

• Interaction: Increased risk of bleeding due to the effect of Mefenamic Acid on platelet function and stomach lining.
• Management: Close monitoring of bleeding signs is required. Dose adjustments or alternative medicines may be considered.

3. Corticosteroids (e.g., Prednisolone, Dexamethasone)

• Interaction: Higher risk of stomach ulcers or gastrointestinal bleeding when used together.
• Management: Doctors may prescribe protective medicines for the stomach and monitor for symptoms like pain or black stools.

4. Antihypertensives (e.g., ACE Inhibitors, Diuretics)

• Interaction: May reduce the effectiveness of blood pressure medicines and increase the risk of kidney-related issues.
• Management: Regular blood pressure and kidney function monitoring is advised. Adequate hydration is important.

5. Methotrexate

• Interaction: Pacimol MF may increase methotrexate levels in the body, raising the risk of toxicity.
• Management: Avoid combination or use under strict medical supervision with regular monitoring.

6. Lithium

• Interaction: May increase lithium levels, leading to potential toxicity such as confusion or tremors.
• Management: Regular monitoring of lithium levels and dose adjustments may be required.

7. Antidiabetic Medicines (e.g., Insulin, Metformin)

• Interaction: May alter blood sugar levels in some individuals.
• Management: Monitor blood glucose regularly and consult your doctor if fluctuations are noticed.

8. Anti-epileptic Drugs (e.g., Phenytoin, Carbamazepine)

• Interaction: These medicines may affect the metabolism of Paracetamol, increasing the risk of liver-related concerns.
• Management: Use cautiously with liver function monitoring, especially during long-term use.

9. Alcohol or Liver-Affecting Drugs

• Interaction: Increased risk of liver damage due to combined effects with Paracetamol.
• Management: Avoid alcohol and use caution with other liver-impacting medicines.

10. Cholestyramine

• Interaction: May reduce the absorption of Paracetamol if taken together.
• Management: Maintain a gap of at least 1–2 hours between both medicines.

Drug - Food interaction

1. High-Fat or Oily Foods

• Interaction: Heavy or fatty meals may slow down the absorption of the medicine, delaying its effect and increasing the chance of stomach discomfort.
• Management: Prefer light, balanced meals when taking the medicine to support better absorption and tolerance.

2. Spicy Foods

• Interaction: Spicy foods may worsen stomach irritation or acidity, especially when combined with anti-inflammatory medicines like Mefenamic Acid.
• Management: Limit spicy and fried foods during the course of treatment to protect the stomach lining.

3. Caffeinated Beverages (Tea, Coffee, Cola)

• Interaction: Excess caffeine may increase restlessness, acidity, or stomach discomfort.
• Management: Reduce intake of caffeinated drinks and switch to water, buttermilk, or herbal beverages.

4. Grapefruit and Citrus Juices

• Interaction: Grapefruit juice may affect liver enzymes and alter how medicines are processed in the body.
• Management: Avoid grapefruit juice unless advised otherwise. Other citrus juices like orange are generally safe in moderation.

5. Low-Fiber Diet

• Interaction: A diet low in fibre may worsen digestion-related issues such as constipation or discomfort.
• Management: Include fibre-rich foods like fruits, vegetables, and whole grains to support digestive health.

6. Empty Stomach Intake

• Interaction: Taking the medicine without food may increase the risk of stomach irritation or nausea.
• Management: Always take Pacimol MF Suspension after meals or with food for better tolerance.

Synopsis

Drug	Paracetamol + Mefenamic Acid
Pharmacological Category	Analgesic and Anti-inflammatory
Therapeutic Indication	Pain and fever relief
Dosage Forms	Oral Suspension

More Information

FAQs About PACIMOL MF SUSPENSION

References

1. Delpharm Bladel BV. Electronic Medicines Compendium (EMC). [Revised in July 2024] [Accessed on 9th April 2026]  

2. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2025] [Accessed on 9th April 2026]  

3. Mefenamic acid and Paracetamol. Centaur pharma. [Accessed on 9th April 2026] 

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Kidney Function Test (KFT)
• Liver Function Test (LFT)
• Serum Electrolytes/ Electrolytes Profile
• Healthy Midlife Checkup
• Men Health Checkup - Advanced
• Complete Women Checkup
• Full Body Checkup - Gold
• Full Body Checkup – Silver