OZOCIL T Tablet 15's

Introduction About OZOCIL T TABLET

OZOCIL T TABLET is a combination of Cilnidipine and Telmisartan which belongs to the group of medicines called Antihypertensive agents. It is used in adults to manage essential hypertension (high blood pressure). Hypertension is a condition in which the force of the blood against the blood vessel walls is too high which is characterized by symptoms such as headache, irregular heartbeat, vision changes, feeling of overtiredness, nausea, vomiting, confusion, anxiety and chest pain.    

OZOCIL T TABLET is not recommended for use in patients with severe liver impairment, advanced aortic stenosis (narrowing of the valve in the large blood vessel branching off the heart (aorta) and primary aldosteronism.    

Before taking OZOCIL T TABLET, inform your doctor if you have diabetes, peripheral edema, metabolic acidosis, cellular lysis (such as acute limb ischemia, rhabdomyolysis, extended trauma) and heart, liver or kidney problems. 

OZOCIL T TABLET is not recommended for use in pregnant and breast-feeding women. OZOCIL T TABLET is not recommended for use in children and adolescents (aged below 18 years). It should be used with caution in elderly patients (aged 65 years and above).

The most common side effects of taking OZOCIL T TABLET are dizziness, headache, flushing, and rash. Consult your doctor if any of the side effects worsen.  

Uses Of OZOCIL T TABLET

Used in adults:

•  To manage essential high blood pressure (hypertension)

How OZOCIL T TABLET Works

OZOCIL T TABLET helps to reduce high blood pressure, where cilnidipine blocks the incoming calcium and suppresses the contraction of blood vessels, thereby reduces the blood pressure. Telmisartan works by relaxing the blood vessels by managing the binding of certain substance (angiotensin-II) resulting in low blood pressure.

How to use OZOCIL T TABLET

Take OZOCIL T TABLET as advised by your physician. Swallow OZOCIL T TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.   

Side Effects Of OZOCIL T TABLET

How To Manage Side Effects

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom did not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve. 

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom did not improve on its own.

Warning & Precautions

Pregnancy

Contraindicated

OZOCIL T TABLET is not recommended for use in pregnant women. Consult your doctor for advice.

Breastfeeding

Contraindicated

OZOCIL T TABLET is not recommended for use in breast-feeding women. Consult your doctor for advice.

Driving and Using Machines

Use with Caution

Do not drive or handle any machines if you experience dizziness after taking OZOCIL T TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking OZOCIL T TABLET as it may cause low blood pressure while standing up from sitting or lying position (orthostatic hypotension).

Kidney

Use with Caution

OZOCIL T TABLET should be used with caution in patients with chronic renal insufficiency. It should be used with caution in patients with impaired kidney function, bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney. Consult your doctor before taking OZOCIL T TABLET.

Liver

Consult your doctor

OZOCIL T TABLET is not recommended for use in patients with severe liver impairment, cholestasis, biliary obstructive disorders. It should be used with caution in patients with mild to moderate liver impairment and elevated liver enzymes. Consult your doctor before taking OZOCIL T TABLET.

Allergy

Contraindicated

Do not take OZOCIL T TABLET if you are allergic to Telmisartan, Cilnidipine or calcium channel antagonists such as amlodipine, nifedipine.

Heart Disease

Consult your doctor

OZOCIL T TABLET is not recommended for use in patients with advanced aortic stenosis (narrowing of the valve in the large blood vessel branching off the heart (aorta)). It should be used with caution in patients with aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy (condition in which the heart muscle becomes abnormally thick), angina (chest pain), ischaemic cardiopathy or ischaemic cardiovascular disease and congestive heart failure. Consult your doctor before taking OZOCIL T TABLET.  

Use In Pediatrics

Contraindicated

OZOCIL T TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

OZOCIL T TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking OZOCIL T TABLET.

Interactions

A. Drug-Drug interactions:

Before taking OZOCIL T TABLET inform your doctor, if you are taking or receiving any of these medicines:

• angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril) angiotensin-II receptor antagonists drugs (Ex. losartan, irbesartan), diuretics (Ex. chlorthalidone, torsemide) and aliskiren (used to manage high blood pressure)
• anti-psychotic drugs such as risperidone, quetiapine (used to manage mental health conditions such as schizophrenia)
• digoxin, quinidine (used to manage heart problems)
• lithium, antidepressants such as paroxetine, fluoxetine (used to manage depression)
• non-steroidal anti-inflammatory drugs such as aspirin or ibuprofen including selective COX-2 inhibitors such as celecoxib (used to manage pain)
• cyclosporin, tacrolimus (used to manage organ rejection after transplant)
• potassium supplements, salt substitutes and potassium-sparing medicines (Ex. spironolactone) (used to manage fluid retention without potassium loss in the urine)
• aldesleukin (used to manage kidney cancer)
• trimethoprim, rifampicin, erythromycin (used to manage bacterial infection)
• baclofen (used to manage relax muscles)
• amifostine (used to protect the kidney from harmful effects of chemotherapy)
• heparin (used to manage or manage blood clots)
• phenytoin, barbiturates such as phenobarbital, pentobarbital (used to manage seizures)
• narcotics such as morphine (used to manage severe pain)

Overdosage:

If you or anyone else accidentally take too much of OZOCIL T TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of OZOCIL T TABLET are low blood pressure, fast or slow heart rate, dizziness, increase in serum creatinine, acute renal failure, excessive peripheral vasodilatation.

Synopsis

More Information

• Keep OZOCIL T TABLET out of reach of children
• Store at room temperature

FAQs About OZOCIL T TABLET

Q: What to do if I miss to take a dose of OZOCIL T TABLET?

A: You should take OZOCIL T TABLET immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.

Q: For how long should I take OZOCIL T TABLET?

A: You should continue taking OZOCIL T TABLET unless your doctor tells you to stop the medicine. Blood pressure medicines will be usually taken for lifetime to manage complications due to high blood pressure. Your doctor may change management with other hypertensive drug, if you do not attain effective therapeutic outcome with OZOCIL T TABLET.

Q: Can OZOCIL T TABLET be taken during pregnancy?

A: OZOCIL T TABLET is not recommended for use in pregnant women. If you think you may be pregnant or planning to get pregnant, consult your doctor before taking this medicine. Inform your doctor immediately if you get pregnant during management with OZOCIL T TABLET. 

Q: Can OZOCIL T TABLET be used in elderly patients?

A: Yes, OZOCIL T TABLET should be used with caution in elderly patients (above 65 years of age). Your doctor may initiate the management with the lowest effective dose which may manage the risk of increased side effects. Consult your doctor before taking OZOCIL T TABLET.   

Q: Is OZOCIL T TABLET safe to use in patients with kidney problems?

A: OZOCIL T TABLET should be used with caution in patients with chronic renal insufficiency. It should be used with caution in patients with impaired kidney function, bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney. Consult your doctor before taking OZOCIL T TABLET.

References

1. KD. Tripathi. Antianginal and other Anti-ischaemic Drugs & Drugs Affecting Renin Angiotensin System. Eighth edition. June 2018. Page – 596 & 536.

2. C Venkata S Ram, Baby Shalini Muppalla, Sarvepalli Vijaya Parthasaradhi, Gajjela Praveen Kumar, Saumitra Ray, Uday Jadhav, J P S Sawhney, Govindan Unni, Nagaraj Desai, Members of the TelCom Study Group. Achieving the Latest American Heart Association and American College of Cardiology Therapeutic Goals for Hypertension With Combination Therapy and Its Effects on Blood Pressure and Central Hemodynamic Parameters. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed.gov. April 2022. [Accessed on October 21st 2022] https://pubmed.ncbi.nlm.nih.gov/35063267/

3. Torrent Pharmaceuticals Ltd. Telsar N (Telmisartan and Cilnidipine Tablets). [Revised in April 2020] [Accessed on October 21st 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2909.pdf

4. Leogenic healthcare. CiniLeo T 10/40 (Cilnidipine and Telmisartan Tablets). [Accessed on October 21st 2022] https://www.leogenic.com/cinileo-t-10-40-cilnidipine-and-telmisartan-tablet/

5. Pure & Cure Healthcare Pvt. Ltd. Cilacar T (Cilnidipine and Telmisartan Tablets). January 2020. [Accessed on October 21st 2022] https://medicaldialogues.in/uploads/2020/05/20/file_upload-129071.pdf

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 28 Jun 2024 | 02:33 PM(IST)