Sun Pharmaceutical Industries Ltd

OVARES A Capsule 15's

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Introduction About OVARES A CAPSULE

Ovares A is a drug that helps improve egg production and quality in women who have a lower number of eggs (Diminished Ovarian Reserve - DOR). It contains a natural hormone that the body converts into estrogen (a female hormone), which is important for healthy egg development. A combination of Dehydroepiandrosterone (DHEA) 25 mg and Folic Acid 1.5 mg that is commonly used as supportive therapy in women undergoing fertility evaluation or assisted reproductive techniques.

OVARES A Capsule is intended for women who have been advised fertility support by a gynecologist or fertility specialist. It may help improve ovarian response, support egg quality, and create favorable conditions for conception when used appropriately. The capsule may be taken with or without food, preferably at the same time each day, and should be swallowed whole with water without crushing or chewing. The dose and duration vary depending on the patient's fertility evaluation, ovarian reserve, hormone profile, and planned fertility procedure. Regular follow-up appointments are important to assess response and determine the appropriate duration of therapy.

Before starting OVARES A Capsule, inform your healthcare professional about any history of hormone-sensitive disorders (such as breast, ovarian, or uterine cancers), polycystic ovary syndrome (PCOS), liver disease, hypertension, diabetes, mood disorders, or blood circulation problems, as these conditions may require additional monitoring. The medicine should only be used under medical supervision, and patients should avoid exceeding the prescribed dose.

OVARES A Capsule is not recommended during pregnancy, as it is intended for use before conception as part of fertility management and may pose a risk to the developing fetus if continued after pregnancy is established. It is also not recommended during breastfeeding, as DHEA may pass into breast milk and its effects on the nursing infant are not well established. If pregnancy occurs during use or is suspected, the medicine should be discontinued only after consulting the healthcare professional.

 Patients should attend all scheduled follow-up visits and report any unusual symptoms, including severe abdominal pain, significant mood changes, jaundice, or signs of an allergic reaction, promptly. Common side effects include acne, oily skin, hair loss, increased facial hair growth, menstrual irregularities, stomach upset, weight gain, and elevated blood pressure. These effects are usually mild but should be discussed with a healthcare professional if persistent or troublesome.

Uses Of OVARES A CAPSULE

  • Ovares A is indicated in women with diminished ovarian reserve.

Benefits of OVARES A CAPSULE

Supports Healthy Ovarian Function

  • Helps maintain hormonal balance required for normal ovarian activity.
  • Supports healthy follicular development and ovarian response.
  • May improve ovarian reserve in appropriately selected patients under specialist care.

Helps Improve Egg Quality

  • Supports the development and maturation of healthy ovarian follicles.
  • May reduce oxidative stress that can affect egg quality.
  • Helps create a favorable ovarian environment before fertility procedures.

Supports Fertility Management

  • Commonly used as an adjunct in women with poor ovarian response or diminished ovarian reserve.
  • May improve ovarian response during assisted reproductive technology (ART) procedures such as IVF when prescribed by a fertility specialist.
  • Supports overall reproductive health during fertility planning.

Provides Essential Folic Acid

  • Supplies folic acid required for DNA synthesis and normal cell division.
  • Supports healthy red blood cell formation.
  • Helps maintain adequate folate levels before conception.

Antioxidant Support

  • DHEA possesses antioxidant properties that may help reduce oxidative stress affecting ovarian cells.
  • Supports healthy cellular function during follicular development.

How OVARES A CAPSULE Works

1. Dehydroepiandrosterone (DHEA)

  • DHEA is a naturally occurring adrenal steroid hormone precursor.
  • It is converted in the body into estrogen and testosterone according to physiological needs.
  • These hormones support normal follicular growth and ovarian function.
  • DHEA may enhance follicular development and improve the ovarian environment in selected women with reduced ovarian reserve.
  • It may also reduce oxidative stress within ovarian tissue, supporting healthier egg development.

2. Folic Acid

  • Folic acid is converted into its active form, tetrahydrofolate.
  • It participates in DNA synthesis, RNA production, and cell division.
  • Supports rapid cell growth during follicular maturation.
  • Maintains normal red blood cell production and folate stores before conception.

Combined Action

Together, DHEA and folic acid:

  • Support healthy ovarian function.
  • Promote healthy follicle and egg development.
  • Improve the nutritional environment for reproductive cells.
  • Support fertility management as part of a specialist-directed managment plan.

How to use OVARES A CAPSULE

Before Taking

  • Take OVARES A Capsule only if prescribed by a gynecologist or fertility specialist.
  • Inform your healthcare professional if you have PCOS, hormone-sensitive disorders, liver disease, diabetes, hypertension, depression, or high cholesterol.
  • Inform your healthcare professional about all medicines, vitamins, and herbal supplements you are taking.

How to Take

  • Take the capsule exactly as prescribed.
  • Swallow the capsule whole with a glass of water.
  • Do not crush, chew, or open the capsule.
  • It may be taken with or without food.
  • Take it at the same time each day to maintain consistent hormone levels.

During Treatment

  • Continue the medicine for the prescribed duration, even if you do not notice immediate changes.
  • Attend regular follow-up appointments for monitoring of ovarian response and fertility planning.
  • Your healthcare professional may monitor hormone levels and ovarian reserve
  • Do not increase or decrease the dose without medical advice.

What if I forgot to take OVARES A CAPSULE

  • Take the missed dose as soon as you remember.
  • Skip the missed dose if it is almost time for your next scheduled dose.
  • Do not take two capsules together.

Overdose

  • There have been no reports of serious harmful effects from taking several doses of this medicine at once.
  • If you have taken too many Ovares A tablets ask your doctor or pharmacist for advice.

Side Effects Of OVARES A CAPSULE

Common

  • Acne
  • Hair loss
  • Deepening of the voice
  • Facia hair growth

Warning & Precautions

Pregnancy

Contraindicated

Ovares A is contraindicated for use in pregnancy.

Breastfeeding

Contraindicated

Ovares A is contraindicated for use in Lactation.

Kidney

Contraindicated

It is not recommended for use in renal impairment (pharmacokinetic data lacking)

Liver

Contraindicated

It is not recommended for use in liver disease (pharmacokinetic data lacking).

Allergy

Contraindicated

Ovares A is not recommended for use in patients allergic to any ingredients of this medicine.

Heart Disease

Contraindicated

It is not recommended for use in active deep vein thrombosis, pulmonary embolism, active arterial thromboembolic disease (for example, stroke and myocardial infarction), or a history of these conditions.

It is also not recommended in hypercholesterolemia and ischemic heart disease.

Use In Pediatrics

Contraindicated

Not recommended for use in children or adolescents unless specifically prescribed by a specialist, as the DHEA component may interfere with normal hormonal development and puberty

Use In Geriatrics

Contraindicated

OVARES A Capsule is generally not intended for elderly women, as it is primarily prescribed for women of reproductive age undergoing fertility management.

Who should not take OVARES A CAPSULE

  • Known hypersensitivity to DHEA, testosterone, estrogens or any component of Ovares A.
  • Undiagnosed abnormal genital bleeding.
  • Known, suspected, or history of breast cancer.
  • History of psychiatric disorders (risk of exacerbation). The risk of mania may be increased during concomitant use with antidepressants (tricyclic or SSRIs) and/or alcohol, or with high prasterone doses, or in patients with a history of mood disorders.

Safety Advice

  • Follow a balanced diet rich in folate and other essential nutrients.
  • Maintain a healthy body weight and follow lifestyle recommendations provided by your fertility specialist.
  • Avoid smoking and excessive alcohol intake, as these may negatively affect fertility.
  • Inform your doctor immediately if pregnancy is confirmed while taking the medicine.

Drug - Drug interaction

Drug-Drug Interactions of OVARES A Capsule 15's

Although no major interactions are reported between DHEA and folic acid themselves, DHEA may interact with several medicines. Always inform your healthcare professional about all medicines you are taking.

1. Hormonal Medicines

Examples:

  • Oral contraceptives
  • Estrogen preparations
  • Progesterone therapy
  • Hormone replacement therapy

Possible Effect:

  • May alter hormone balance.
  • Increased risk of hormonal adverse effects.
  • May influence response during fertility management.

2. Antidiabetic Medicines

Examples:

  • Metformin
  • Insulin
  • Glimepiride
  • Gliclazide

Possible Effect:

  • DHEA may influence insulin sensitivity.
  • Blood glucose levels may change.
  • Blood sugar monitoring may be required.

3. Corticosteroids

Examples:

  • Prednisolone
  • Dexamethasone
  • Hydrocortisone

Possible Effect:

  • May alter the hormonal effects of DHEA.
  • Clinical response may require monitoring.

4. Antiepileptic Medicines

Examples:

  • Phenytoin
  • Carbamazepine
  • Phenobarbital

Possible Effect:

  • May alter DHEA metabolism.
  • Could reduce therapeutic effectiveness.

5. Antidepressants

Examples:

  • Fluoxetine
  • Sertraline
  • Paroxetine

Possible Effect:

  • DHEA may increase the risk of mood changes or manic symptoms in susceptible individuals.
  • Patients with psychiatric disorders require careful monitoring.

6. Testosterone or Other Androgen Products

Examples:

  • Testosterone
  • Androgen replacement therapies

Possible Effect:

  • May increase androgen-related effects such as acne, oily skin, and excessive hair growth.

Synopsis

Drug

Dehydroepiandrosterone (DHEA) and Folic Acid

Pharmacological Category

Hormonal and Nutrient supplement

Therapeutic Indication

In women with diminished ovarian reserve

Dosage Forms

Capsule

More Information

1. Why OVARES A Capsule Is Prescribed Before Fertility Procedures

OVARES A Capsule is often prescribed before assisted reproductive techniques (ART), such as in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), when a fertility specialist identifies reduced ovarian reserve or a poor ovarian response. The DHEA component supports the hormonal environment required for healthy follicular development, while folic acid supports rapid cell division and DNA synthesis during the early stages of reproductive cell growth.

Patient Education

  • Usually started several weeks or months before a planned fertility procedure, depending on the management plan.
  • Should be taken regularly without skipping doses to maintain consistent hormone levels.
  • The duration of therapy varies based on ovarian reserve, age, and fertility goals.
  • Regular follow-up visits help assess the response to medicine and guide further management.

2. Importance of Lifestyle During Fertility Support

Medicines are one part of fertility care. Healthy lifestyle habits can complement specialist-directed therapy and support overall reproductive health.

Healthy Lifestyle Tips

  • Eat a balanced diet rich in folate, iron, protein, omega-3 fatty acids, fruits, and vegetables.
  • Maintain a healthy body weight, as being underweight or overweight may influence reproductive function.
  • Engage in regular moderate physical activity unless advised otherwise.
  • Aim for 7–9 hours of quality sleep each night.
  • Practice stress-management techniques such as yoga, meditation, or relaxation exercises.
  • Avoid smoking, recreational drugs, and excessive alcohol intake, as these may negatively affect reproductive health.

3. Why Regular Monitoring Is Important

Since OVARES A Capsule contains DHEA, periodic medical evaluation helps ensure that therapy remains appropriate and well tolerated.

What Your Healthcare Professional May Monitor

  • Ovarian reserve markers such as Anti-Müllerian Hormone (AMH).
  • Hormone profile, when clinically indicated.
  • Ultrasound assessment of follicular development during fertility management.
  • Response to therapy and the need for continuation or adjustment.
  • Any androgen-related effects, such as acne, oily skin, or unwanted hair growth.

When to Seek Medical Advice

Contact your healthcare professional if you experience:

  • Severe abdominal pain.
  • Significant menstrual changes.
  • Persistent mood changes.
  • Signs of an allergic reaction, such as rash, swelling, or difficulty breathing.

FAQs About OVARES A CAPSULE

Q: What is Reluease?

A: Reluease is a prescription medicine used to treat heavy menstrual bleeding caused by uterine fibroids in premenopausal women. It contains three active ingredients Relugolix, Estradiol, and Norethisterone acetate that work together to manage bleeding and protect bone health.

Q: How does Reluease work?

A: Reluease helps reduce hormone levels that contribute to fibroid symptoms and provides low-dose estrogen and progesterone to maintain hormonal balance and protect bones.

Q: Who can take Reluease?

A: Reluease is recommended for women with heavy menstrual bleeding due to fibroids who are not pregnant and not breastfeeding. Your doctor will confirm if it is suitable for you.

Q: Can I use birth control while on Reluease?

A: Hormonal contraceptives should not be used together with Reluease. Your doctor will advise safe alternatives.

Q: How soon will I notice improvement?

A: Many women notice improvement in bleeding within the first few weeks, but response may vary. Continue treatment as advised.

Q: Can I drive or operate machines while on Reluease?

A: Yes. Reluease has no known effects on driving or using machines.

Q: Does food affect Reluease?

A: No there are no meaningful food interactions. You may take it with or without food.

Q: How long do I need to take it?

A: Your doctor will decide the treatment duration based on your symptoms and response.

Q: Will Reluease affect fertility?

A: Reluease does not act as a contraceptive, and fertility returns after stopping. Discuss family planning needs with your doctor.

Q: Can Reluease reduce fibroid size?

A: Reluease mainly reduces bleeding symptoms. Your doctor may monitor fibroid size through scans if needed.

Q: What should I tell my doctor before starting Reluease?

A: Share your medical history, pregnancy plans, liver problems, clotting disorders, migraines, or history of hormone-related cancers.

References

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page-1062-1064

2. Meixiang Zhang, Wenbin Niu, Yu Wang, Jiawei Xu, Xiao Bao, Linlin Wang, Linqing Du, and Yingpu Sun. Dehydroepiandrosterone treatment in women with poor ovarian response undergoing IVF or ICSI: a systematic review and meta-analysis. US National Library of Medicines, National Institutes of Health. April 2016. [Accessed on 27th July 2026] click here

3. Center for Human Reproduction. Study of Oral Dehydroepiandrosterone (DHEA) to Treat Previously Unexplained Infertility (DHEAFert). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2015] [Accessed 27th July 2026] click here 

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