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Introduction About OSTOSPRAY 2200IU SPRAY
OSTOSPRAY 2200IU SPRAY contains Calcitonin which belongs to the group of medicines called Calcium metabolism modifiers. It is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other managements are not appropriate.
Prior to the management, the doctor will perform a skin test to determine whether you are allergic to calcitonin or not. During management with OSTOSPRAY 2200IU SPRAY, your doctor may take several bone-related tests to evaluate improvement in your condition. You may also be prescribed vitamin D or calcium supplements along with OSTOSPRAY 2200IU SPRAY to improve your disease condition.
Before using OSTOSPRAY 2200IU SPRAY, inform your doctor if you have low blood calcium levels or any type of cancer as a precaution. Do not use OSTOSPRAY 2200IU SPRAY without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of using OSTOSPRAY 2200IU SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
Uses Of OSTOSPRAY 2200IU SPRAY
It is used among women (greater than 5 years of menopause) to:
- Manage postmenopausal osteoporosis
How OSTOSPRAY 2200IU SPRAY Works
OSTOSPRAY 2200IU SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action manages bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
How to use OSTOSPRAY 2200IU SPRAY
Use OSTOSPRAY 2200IU SPRAY as advised by your physician. It is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
As OSTOSPRAY 2200IU SPRAY must be stored in the refrigerator, allow it to come to room temperature before use.
Your doctor will decide the suitable dose, number of sprays, and duration of therapy for you depending upon your age, body weight, and health condition. Do not stop using OSTOSPRAY 2200IU SPRAY without consulting your doctor.
Side Effects Of OSTOSPRAY 2200IU SPRAY
Common
- back pain, muscle pain
- headache
- runny nose
- nasal irritation or dryness
Rare
Stop using OSTOSPRAY 2200IU SPRAY and contact your doctor immediately if you experience any of the following side effects, such as:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, eyes, tongue, or throat causing wheezing or difficulty breathing, chest tightness, a fall in blood pressure, or an increased heartbeat)
- signs of hypocalcemia (such as tingling or numbness of fingers, toes, or around the mouth)
- severe nasal irritation with nasal bleeding, redness, swelling or soreness, crusting sensation, and nasal dryness
How To Manage Side Effects

Headache
Rest and relax. Drink plenty of fluids, such as water or electrolytes, and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if the symptom does not improve.
Warning & Precautions

Pregnancy
Consult your doctorThere are no adequate studies to confirm the effects of OSTOSPRAY 2200IU SPRAY on pregnant women. Therefore, OSTOSPRAY 2200IU SPRAY should be used in pregnant women only if considered necessary by the physician.

Breastfeeding
Consult your doctorThere are no adequate studies to confirm whether OSTOSPRAY 2200IU SPRAY can pass through breast milk or not. Therefore, OSTOSPRAY 2200IU SPRAY should be used in breastfeeding women only if considered necessary by the physician.

Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your abilities are affected by OSTOSPRAY 2200IU SPRAY.

Allergy
ContraindicatedTalk to your doctor before using OSTOSPRAY 2200IU SPRAY if you are allergic to calcitonin.

Use In Pediatrics
ContraindicatedOSTOSPRAY 2200IU SPRAY is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.

Use In Geriatrics
Use with CautionOSTOSPRAY 2200IU SPRAY should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before using it.
Others
Before using OSTOSPRAY 2200IU SPRAY, inform your doctor if you have:
- hypocalcaemia (low calcium levels in the blood)
- any form of cancer
Interactions
A. Drug-Drug interactions:
Before using OSTOSPRAY 2200IU SPRAY, inform your doctor if you are taking any of the following medicines, such as:
- medicines used to manage depression and mania (Ex. lithium)
- other medicines used to manage osteoporosis (Ex. alendronate, zoledronic acid)
Overdosage:
If you or anyone else accidentally took more OSTOSPRAY 2200IU SPRAY, contact your doctor or go to the nearest hospital right away.
Synopsis
Drug | : | Calcitonin |
Pharmacological Category | : | Calcitonin Receptor Agonist |
Therapeutic Indication | : | Postmenopausal Osteoporosis |
Dosage Forms | : | Injection, Nasal Spray |
More Information
- Keep OSTOSPRAY 2200IU SPRAY out of the sight and reach of children
- Store in a refrigerator between 2-8°C
FAQs About OSTOSPRAY 2200IU SPRAY
Q: What is the use of OSTOSPRAY 2200IU SPRAY?
A: OSTOSPRAY 2200IU SPRAY is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other managements are not appropriate.
Q: How do I use OSTOSPRAY 2200IU SPRAY?
A: OSTOSPRAY 2200IU SPRAY is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
Q: What are the side effects of OSTOSPRAY 2200IU SPRAY?
A: The most common side effects of using OSTOSPRAY 2200IU SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
Q: Can elderly patients use OSTOSPRAY 2200IU SPRAY?
A: Yes, elderly patients can use OSTOSPRAY 2200IU SPRAY after consulting their doctor.
Q: Can OSTOSPRAY 2200IU SPRAY manage osteoporosis?
A: Yes. OSTOSPRAY 2200IU SPRAY helps in managing osteoporosis and helps in gaining back lost bone mass in postmenopausal women.
Q: How does OSTOSPRAY 2200IU SPRAY work?
A: OSTOSPRAY 2200IU SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action manages bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
Q: Can I stop therapy with OSTOSPRAY 2200IU SPRAY once my symptoms subside?
A: No. Do not stop using OSTOSPRAY 2200IU SPRAY without consulting your doctor once your symptoms subside, as it may reverse the healed condition. Continue to use OSTOSPRAY 2200IU SPRAY as long as instructed by your doctor.
Q: Can OSTOSPRAY 2200IU SPRAY cause cancer?
A: Yes. OSTOSPRAY 2200IU SPRAY might cause cancer when used in the long term. Therefore, contact your doctor for advice before using it.
References
1. KD. Tripathi. Drugs affecting Calcium Balance. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 340.
2. C H Chesnut 3rd 1, S Silverman, K Andriano, H Genant, A Gimona, S Harris, D Kiel, M LeBoff, M Maricic, P Miller, C Moniz, M Peacock, P Richardson, N Watts, D Baylink. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. Pubmed.gov. September 2000. [Accessed on 1st February 2024] https://pubmed.ncbi.nlm.nih.gov/10996576/
3. Novartis Pharma Stein AG. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020313s036lbl.pdf
4. Novartis Pharmaceutical Corporation. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020313s033lbl.pdf
5. Par Pharmaceutical. Calcitonin. [Revised in June 2016] [Accessed on 1st February 2024] https://www.parsterileproducts.com/pdfs/catalog/generic/Calcitonin_PI_20200506.pdf
6. Calcitonin. Apotex Inc. [Revised in November 2017] [Accessed on 1st February 2024] https://www1.apotex.com/products/us/downloads/pil/calc_naso_pil.pdf
7. Apotex Corp. Dailymed. [Revised in January 2021] [Accessed on 1st February 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c82eb602-12e1-692b-d660-f8d5b5736b54&audience=professional
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