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Introduction About OSTIUM K2 FORTE TABLET
OSTIUM K2 FORTE TABLET is a combination of Calcitriol, Vitamin K2 7(Menaquinone), Elemental Zinc, and Elemental Magnesium which belongs to the group of medicines called Vitamins and Minerals, respectively. It is used in the management of osteoporosis in affected individuals. Osteoporosis is a condition that cause bones to become weak and brittle which is generally characterized by symptoms such as back pain, stooped posture, and/or loss of height over time in affected individuals.
OSTIUM K2 FORTE TABLET is not recommended for use in patients allergic to Calcitriol, and/other vitamin D metabolites (such as alfacalcidol, colecalciferol). It is also not recommended for use in patients suffering from hypercalcemia (high calcium levels in blood), and/or metastatic calcification (extra deposits of calcium in your body).
Before taking [GBNKEWYORD], inform your doctor if you are immobilized (due to operation/any other reason), and/or have liver problems (such as non-alcoholic fatty liver disease).
OSTIUM K2 FORTE TABLET should be used with caution in pregnant and breast-feeding women only if it is clearly necessary. It is also advised to be used with caution in children and adolescents (aged below 18 years) and in elderly patients (aged 65years and above) after consulting your doctor.
The most common side effects associated with the use of OSTIUM K2 FORTE TABLET are hypercalcemia (high calcium levels in blood), headache, skin rash, excess thirst, nausea. abdominal pain, and/or urinary tract infection. Consult your doctor if any of these symptoms worsens.
Uses Of OSTIUM K2 FORTE TABLET
- Aids in the management of osteoporosis in affected individuals
How OSTIUM K2 FORTE TABLET Works
OSTIUM K2 FORTE TABLET helps in the management of osteoporosis, where calcitriol works by aiding the body to absorb more calcium from food/supplements which also regulates the production of parathyroid hormone (chemical responsible for maintaining the balance between calcium and phosphorus in the body), vitamin K2-7 increases healthy bone deposits by increasing collagen production through osteoblastic cells and managing calcium deposits in the arteries, and elemental zinc & magnesium enhances bone regeneration by improving bone health through initiation of certain pathways and reducing the activity of bone resorbing cell thus helping in the management of osteoporosis in affected individuals.
How to use OSTIUM K2 FORTE TABLET
Take OSTIUM K2 FORTE TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of OSTIUM K2 FORTE TABLET
Common
- signs of hypercalcemia (increased calcium levels in blood) such as tiredness, weakness, vomiting, excessive urination, high blood pressure
- headache
- skin rash
- excess thirst
- nausea
- abdominal pain
- urinary tract infection
Uncommon
- high blood pressure
- drowsiness
- high fever
- anorexia (eating disorder)
- ophthalmic conditions such as conjunctivitis, photophobia
Rare
- signs of hypercalcemia (increased calcium levels in blood) such as loss of appetite, weight loss, nausea, vomiting, headache, sluggishness, drowsiness, weakness,
- signs of extreme hypercalcemia (very high calcium levels in blood) such as high fever, thirsty, dehydration, passing more urine, wetting the bed, constipation, stomach pain, blockage of the bowel, irregular heartbeat, urinary bladder infection, restricted growth, and/or mental problems.
- signs of allergic reactions such as itchy skin, skin rashes, and/or reddening of the skin.
Stop taking OSTIUM K2 FORTE TABLET and contact your doctor if you experience any of the following side effects:
- signs of severe allergic reactions such as itchy skin, skin rashes, and reddening of the skin
How To Manage Side Effects
Headache:
If OSTIUM K2 FORTE TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking OSTIUM K2 FORTE TABLET. If it lasts more than a week or severe, inform your doctor.
Nausea
Try to take OSTIUM K2 FORTE TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Thirst:
Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.
Warning & Precautions
Pregnancy
OSTIUM K2 FORTE TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.
Breastfeeding
OSTIUM K2 FORTE TABLET should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before taking the medicine.
Driving and Using Machines
OSTIUM K2 FORTE TABLET is unlikely to affect your ability to drive or operate machines. Consult your doctor before taking the medicine.
Kidney
OSTIUM K2 FORTE TABLET should be used with caution in patients with kidney problems such as renal osteodystrophy. Consult your doctor before taking the medicine.
Liver
OSTIUM K2 FORTE TABLET should be used with caution in patients with liver problems such as non-alcoholic fatty liver disease. Consult your doctor before taking the medicine.
Allergy
Do not take OSTIUM K2 FORTE TABLET if you are allergic to Calcitriol, other vitamin D metabolites (such as alfacalcidol, colecalciferol), and/or any other ingredients of this medicine. Consult your doctor before taking the medicine.
Others
OSTIUM K2 FORTE TABLET is not recommended for use if you:
- have hypercalcemia (high calcium levels in blood)
- have metastatic calcification (extra deposits of calcium in your body)
- are unwell due to high levels of vitamin D in your body
Before taking OSTIUM K2 FORTE TABLET, inform your doctor if you:
- are immobilized due to operation or any other reason
Use in Paediatrics
OSTIUM K2 FORTE TABLET should be used with caution in children and adolescents (below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics
OSTIUM K2 FORTE TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
Interactions
OSTIUM K2 FORTE TABLET is not recommended for use if you:
- have hypercalcemia (high calcium levels in blood)
- have metastatic calcification (extra deposits of calcium in your body)
- are unwell due to high levels of vitamin D in your body
Before taking OSTIUM K2 FORTE TABLET, inform your doctor if you:
- are immobilized due to operation or any other reason
Use in Paediatrics
OSTIUM K2 FORTE TABLET should be used with caution in children and adolescents (below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics
OSTIUM K2 FORTE TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
Synopsis
| Drug | : | Calcitriol, Vitamin K2 7(Menaquinone), Elemental Zinc, and Elemental Magnesium |
| Pharmacological Category | : | Minerals and Vitamins |
| Therapeutic Indication | : | Osteoporosis |
| Dosage Forms | : | Tablets |
More Information
- Keep the medicine out of reach in children
- Store OSTIUM K2 FORTE TABLET at room temperature
FAQs About OSTIUM K2 FORTE TABLET
What OSTIUM K2 FORTE TABLET is used for?
OSTIUM K2 FORTE TABLET is used in the management of osteoporosis which causes bones to become weak and brittle which is generally characterized by symptoms such as back pain, stooped posture, and/or loss of height over time in affected individuals.
What happens if you take more OSTIUM K2 FORTE TABLET than your required dose?
If you or anyone else accidentally takes too much of OSTIUM K2 FORTE TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage includes signs of hypercalcemia such as loss of appetite, weight loss, nausea, vomiting, constipation, headache, sluggishness, drowsiness, and/or weakness.
What side effects are seen with OSTIUM K2 FORTE TABLET?
The most common side effects associated with the use of OSTIUM K2 FORTE TABLET are hypercalcemia (high calcium levels in blood), headache, skin rash, excess thirst, nausea. abdominal pain, and/or urinary tract infection. Consult your doctor if any of these symptoms worsens.
Who should avoid taking OSTIUM K2 FORTE TABLET?
OSTIUM K2 FORTE TABLET is not recommended for use in patients allergic to Calcitriol, other vitamin D metabolites (such as alfacalcidol, colecalciferol), and/or any other ingredients of this medicine. It is also not recommended for use in patients with hypercalcemia (high calcium levels in blood), and/or metastatic calcification (extra deposits of calcium in your body). Consult your doctor before taking the medicine.
Is OSTIUM K2 FORTE TABLET safe to use in children or elderly patients?
Yes, OSTIUM K2 FORTE TABLET can be used but with caution in children and adolescents (below 18 years) and in elders (aged above 65 years). Consult your doctor before taking the medicine.
How OSTIUM K2 FORTE TABLET works?
OSTIUM K2 FORTE TABLET helps in the management of osteoporosis, where calcitriol works by aiding the body to absorb more calcium from food/supplements which also regulates the production of parathyroid hormone (chemical responsible for maintaining the balance between calcium and phosphorus in the body), vitamin K2-7 increases healthy bone deposits by increasing collagen production through osteoblastic cells and managing calcium deposits in the arteries, and elemental zinc & magnesium enhance bone regeneration by improving bone health through initiation of certain pathways and reducing the activity of bone resorbing cell thus helping in the management of osteoporosis in affected individuals.
Is OSTIUM K2 FORTE TABLET safe to use in pregnant and breastfeeding women?
Yes, OSTIUM K2 FORTE TABLET can be used but with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is also used with caution in breastfeeding women if deemed clearly necessary by the consulting doctor. Consult your doctor before taking the medicine.
What if I forget to take OSTIUM K2 FORTE TABLET dose?
If you forgot to take OSTIUM K2 FORTE TABLET dose, take it as early as possible when you remember. Do not double the dose to make up for the missed dosage. Consult your doctor if you have doubts on missed dosage.
References
1. KD. Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page 341.
2. J. Patrick O’Connor, Deboleena Kanjilal, Marc Teitelbaum, Sheldon S. Lin, and Jessica A. Cottrell. Zinc as a Therapeutic Agent in Bone Regeneration. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. May 2020. [Accessed on 8th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287917/
3. Sara Castiglioni, Alessandra Cazzaniga, Walter Albisetti, Jeanette A M Maier. Magnesium and osteoporosis: current state of knowledge and future research directions. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed.gov. July 2013. [Accessed on 8th September 2022] https://pubmed.ncbi.nlm.nih.gov/23912329/
4. Brandon E. Lung; Myles L. Mowery; David E E. Komatsu. Calcitriol. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. July 2022. [Accessed on 8th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK526025/
5. Hamid Lorvand Amiri, Shahram Agah , Javad Tolouei Azar , Sharieh Hosseini , Farzad Shidfar , Seyedeh Neda Mousavi. Effect of daily calcitriol supplementation with and without calcium on disease regression in non-alcoholic fatty liver patients following an energy-restricted diet: Randomized, controlled, double-blind trial. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed.gov. September 2016. [Accessed on 8th September 2022] https://pubmed.ncbi.nlm.nih.gov/27720403/
6. Ji Yeon Lee, Tsz-Yin So, and Jennifer Thackray. A Review on Vitamin D Deficiency Treatment in Pediatric Patients. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2013. [Accessed on 8th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979050/
7. Meghan Meehan, Sue Penckofer. The Role of Vitamin D in the Aging Adult. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2014. [Assessed on 8th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399494/
8. Atnahs Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 8th September 2022] https://www.medicines.org.uk/emc/files/pil.11802.pdf
9. Medley Pharmaceuticals Ltd. Ostium K2 Forte 15. [Accessed on 8th September 2022] https://www.medleylab.com/product/Osteokare/anti-osteoporotic.html
Useful Diagnostic Tests
- Dual X-ray absorptiometry
- Blood tests
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