OPTIDEX Eye/Ear Drops 5ml

Introduction About OPTIDEX EYE/EAR DROPS

OPTIDEX EYE/EAR DROPS is a combination of Chloramphenicol and Dexamethasone which belongs to the group of medicines called Antibiotics and Corticosteroids respectively. It is used to manage bacterial eye or ear infections. It is used to manage eye infections such as conjunctivitis (inflammation of the conjunctiva) and ear infections such as otitis media (middle ear infections) in children with ear tubes and otitis externa (outer ear infections) in adults and children.

During course of the management your doctor might regularly examine your eye and ear to avoid any untoward side effects. OPTIDEX EYE/EAR DROPS should be used with caution in infants and children (2 years or younger). It is not recommended for use in new-borns. Before using OPTIDEX EYE/EAR DROPS, inform your doctor if you have an injury or ulcer of the cornea, viral or fungal eye infections, severe blood disorders, liver problems, or family history of impaired bone marrow function.

OPTIDEX EYE/EAR DROPS is not recommended for use in pregnant and breastfeeding women. The most common side effects of using OPTIDEX EYE/EAR DROPS are itching, red or swollen eyelid, foreign body sensation or appearance of other signs of irritation. Contact your doctor if any of the side effects worsen or persists for a longer duration.

Uses Of OPTIDEX EYE/EAR DROPS

It is used to manage:

• bacterial eye and ear infections (conjunctivitis, otitis media, otitis externa)  
• bacterial eye infections (inflammations of the eye)

How OPTIDEX EYE/EAR DROPS Works

OPTIDEX EYE/EAR DROPS manages infection and inflammation where Chloramphenicol belongs to antibiotic which stops bacterial growth in the eye/ear by managing the synthesis of essential proteins required by the bacteria to carry out vital functions. Dexamethasone with anti-inflammatory properties which acts by inhibiting the chemicals such as prostaglandins that cause inflammation. It also reduces symptoms associated with infection such as redness and irritation of the eye/ear.

How to use OPTIDEX EYE/EAR DROPS

Use OPTIDEX EYE/EAR DROPS as advised by your physician. It is for external use only. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the infection.

Side Effects Of OPTIDEX EYE/EAR DROPS

Warning & Precautions

Pregnancy

Contraindicated

OPTIDEX EYE/EAR DROPS is not recommended for use in pregnant women. Consult your doctor before using it.

Breastfeeding

Contraindicated

OPTIDEX EYE/EAR DROPS is not recommended for use in breastfeeding women. Consult your doctor before using it.

Driving and Using Machines

Use with Caution

Do not drive or operate machinery if you experience blurred vision or other disturbances after using OPTIDEX EYE/EAR DROPS.

Liver

Contraindicated

OPTIDEX EYE/EAR DROPS is not recommended for use in patients with known impaired liver function. Consult your doctor before using it.

Allergy

Contraindicated

Do not use OPTIDEX EYE/EAR DROPS if you are allergic to Chloramphenicol, Dexamethasone, or any of the other ingredients of this medicine.

Use In Pediatrics

Contraindicated

OPTIDEX EYE/EAR DROPS is not recommended for use in newborns aged up to 28 days. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.

Use In Geriatrics

Consult your doctor

Your doctor will prescribe the right dose depending on your age, body weight and health condition. Consult your doctor before using OPTIDEX EYE/EAR DROPS.

Interactions

A. Drug-Drug interactions:

Before using OPTIDEX EYE/EAR DROPS inform your doctor if you are using any of the following medicines:

• medicines used to manage bacterial infections (Ex. penicillin, cephalosporin, gentamicin, tetracycline, vancomycin)
• medicines used to manage diabetes (Ex. glimepiride, glyburide)
• medicines used to reduce blood clots (Ex. warfarin, hydroxycoumarin)
• medicines used to manage fits (Ex. phenytoin, ethotoin)
• methotrexate (used to manage certain types of cancer)
• medicines used to relieve pain and inflammation (Ex. diclofenac, indomethacin)

Overdosage:

If you or anyone else accidentally uses too much of OPTIDEX EYE/EAR DROPS, contact your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep OPTIDEX EYE/EAR DROPS out of reach of children
• Store below 25°C

FAQs About OPTIDEX EYE/EAR DROPS

Q: Can I use OPTIDEX EYE/EAR DROPS after having a cataract surgery?

A: In case you have recently had a cataract surgery, using OPTIDEX EYE/EAR DROPS may delay healing and increase the risk of blister formation in the eye. Consult your doctor before using it.

Q: Can I use OPTIDEX EYE/EAR DROPS if I have diabetes?

A: Before using OPTIDEX EYE/EAR DROPS, inform your doctor if have diabetes. You may have a risk of increased eye pressure or formation of cataract. In this case, your doctor will evaluate the benefits and risks for you from this management.

Q: How long can I use OPTIDEX EYE/EAR DROPS for?

A: Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. It should not be used for longer than 10 days. You must talk to your doctor if you do not feel better after 3 days from the start of management.

Q: What if I use more than required amount of OPTIDEX EYE/EAR DROPS or accidentally swallow it?

A: If you use more than required amount of OPTIDEX EYE/EAR DROPS, wash your eye/ear thoroughly with lukewarm water. In case you have accidentally swallowed it, consult your doctor immediately.

Q: What if I forget to use a dose of OPTIDEX EYE/EAR DROPS?

A: If you forget to use a dose of OPTIDEX EYE/EAR DROPS use it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not use the medicine twice to make up for a forgotten dose.

Q: Can I stop using OPTIDEX EYE/EAR DROPS?

A: Do not stop using OPTIDEX EYE/EAR DROPS without consulting your doctor, as it may make your symptoms reappear or make the bacteria resistant to the management. If you have any more doubts regarding the use of this medicine, consult your doctor.

References

1. KD. Tripathi. Corticosteroids. Tetracyclines and Chloramphenicol.  Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 289, 739.

2. Ginny C. Oong; Prasanna Tadi. Chloramphenicol. StatPearls. StatPearls Publishing. November 2021. [Accessed on 10th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK555966/#article-19435.s3

3. Donavon B. Johnson; Michael J. Lopez; Brendan Kelley. Dexamethasone. StatPearls [Internet]. StatPearls Publishing. May 2022. [Accessed on 10th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK482130/#:~:text=Dexamethasone%20is%20a%20potent%20glucocorticoid,becomes%20less%20permeable%2C%20as%20well.

4. Balkanpharma-Razgrad AD. Chloramphenicol+Dexamethasone. [Revised in October 2013] [Accessed on 10th June 2022] http://www.antibiotic.bg/uploads//e72c26cf4a763e0af4764503fa9c8e8d5b3c2bd9.pdf

5. American Academy of Opthalmology. Inflammation. [Accessed on 10th June 2022] https://www.aao.org/eye-health/symptoms/inflammation

6. Integrate Laboratories. Chloramphenicol Dexamethasone (Retchlor-D). [Accessed on 10th June 2022] https://integratedlaboratories.in/chloramphenicol-dexamethasone-retchlor-d/

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Purvi Raghuvanshi - MBBS, ENT

Last updated on 02 Mar 2023 | 12:50 PM(IST)