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Introduction About OPTICHLOR P EYE DROPS
OPTICHLOR P EYE DROPS is a combination of Chloramphenicol and Polymyxin B which belongs to the group of medicines called Antibiotics. It is used in adults to manage bacterial infections of the eyes and ear canal. Eye infection is characterized by warmth, redness, swelling and pain. Ear infection can show symptoms like ear pain, fever, irritability, rubbing or tugging ear or difficulty sleeping.
During course of the management your doctor might regularly examine your eye and ear to avoid any untoward side effects. The safety and effectiveness of OPTICHLOR P EYE DROPS have not been established in children.
Before using OPTICHLOR P EYE DROPS, inform your doctor if you have a family history of blood disorders or if you wear contact lenses. OPTICHLOR P EYE DROPS is not recommended for use in pregnant or breastfeeding women.
The most common side effects of using OPTICHLOR P EYE DROPS are temporary burning, stinging, irritation, itching, redness, blurry eyesight, light sensitivity or allergic reaction. Consult your doctor if any of the side effects worsen.
Uses Of OPTICHLOR P EYE DROPS
- Manage bacterial infections of the eyes and ear canal
How OPTICHLOR P EYE DROPS Works
OPTICHLOR P EYE DROPS manages infection, where chloramphenicol binds to the 50S ribosomal subunit, managing the formation of bacterial protein and polymyxin B interacts with certain molecules of the outer membrane of infecting bacteria, changing membrane permeability and killing the cell.
How to use OPTICHLOR P EYE DROPS
Use OPTICHLOR P EYE DROPS as advised by your doctor. It is for external use only. Do not touch the tip of the dropper on any surface. Squeeze the dropper gently, then dispense the medication inside the lower eyelid or ear. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition and body weight.
Side Effects Of OPTICHLOR P EYE DROPS
Common
- temporary burning, stinging, irritation, itching, redness
- blurry eyesight
- light sensitivity
- allergic reaction
How To Manage Side Effects
Eye irritation or itching:
Wash your eyes with plain cold water. Place an ice pack on your eye to soothe the irritation. Avoid straining your eyes by keeping away from mobile phones, laptops or television. Wear protective sunglasses while going outdoors.
Blurred vision:
Avoid driving or going outside on your own if you have blurred vision. Close your eyes for some time until your eyesight gets clear. Consult your doctor if your vision remains blur for a long period.
Warning & Precautions
Pregnancy
OPTICHLOR P EYE DROPS is not recommended for use in pregnant women. Consult your doctor before using it.
Breastfeeding
OPTICHLOR P EYE DROPS is not recommended for use in breastfeeding women. Consult your doctor before using it.
Driving and Using Machines
Do not drive or operate machinery if you are not sure if you have complete mental and physical alertness or motor coordination after using OPTICHLOR P EYE DROPS.
Kidney
OPTICHLOR P EYE DROPS should be used with caution in patients with kidney failure. Consult your doctor before using it.
Liver
OPTICHLOR P EYE DROPS should be used with caution in patients with liver impairment. Consult your doctor before using it.
Allergy
Do not use OPTICHLOR P EYE DROPS if you are allergic to Chloramphenicol, Polymyxin B or any other ingredients of this medicine.
Others
OPTICHLOR P EYE DROPS is not recommended for use if you:
- had experienced bone marrow suppression during previous exposure to chloramphenicol
- have known personal or family history of blood dyscrasias including aplastic anaemia
Before using OPTICHLOR P EYE DROPS, inform your doctor if you:
- are going to use this medicine on a long-term or intermittent basis
- have severe bacterial conjunctivitis or an infection which is not confined to the conjunctivae
- wear contact lenses
Use in pediatrics:
The safety and effectiveness of OPTICHLOR P EYE DROPS have not been established in children. Consult your child’s doctor for advice.
Use in geriatrics:
The safety and effectiveness of OPTICHLOR P EYE DROPS have not been established in elderly patients. Consult your doctor before using it.
Interactions
A. Drug-Drug interactions:
Before using OPTICHLOR P EYE DROPS, inform your doctor if you are using any of the following medicines:
- neomycin (used to manage bacterial eye infections)
Overdosage:
If you or anyone else accidentally use too much of OPTICHLOR P EYE DROPS, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Chloramphenicol, Polymyxin B |
| Pharmacological Category | : | Nitrobenzene derivative, Polypeptide antibiotic |
| Therapeutic Indication | : | Bacterial infection of eye or ear canal |
| Dosage Forms | : | Eye/Ear drops, Eye/Ear ointment |
More Information
- Keep OPTICHLOR P EYE DROPS out of reach of children
- Store in a cool place
FAQs About OPTICHLOR P EYE DROPS
Q: Can OPTICHLOR P EYE DROPS be used for fungal infections?
A: No, OPTICHLOR P EYE DROPS is used in patients with bacterial infections. Do not use this medicine for any other indication than prescribed for. Consult your doctor before using it for other purposes.
Q: Can I wear contact lenses while using OPTICHLOR P EYE DROPS?
A: No, all types of contact lenses should be avoided when you are being managed for eye infections. Call you doctor for further queries regarding OPTICHLOR P EYE DROPS use.
Q: Can I stop using OPTICHLOR P EYE DROPS on my own?
A: Do not stop using OPTICHLOR P EYE DROPS unless your doctor advises you to do so. You might need to discontinue using it in case any new infections or serious side effects occur. Call you doctor for further queries regarding OPTICHLOR P EYE DROPS use.
Q: Can OPTICHLOR P EYE DROPS be used in children?
A: The safety and effectiveness of OPTICHLOR P EYE DROPS is not established in children. Your child’s doctor will select a suitable alternative management for your child to manage the infection.
Q: What if I forget to use a dose of OPTICHLOR P EYE DROPS?
A: If you forget to use a dose of OPTICHLOR P EYE DROPS, use it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not use the medicine two times to make up for a forgotten dose.
Q: What precautions do I need to follow while using OPTICHLOR P EYE DROPS?
A: Patients using OPTICHLOR P EYE DROPS must inform their doctor about their pre-existing disease conditions like a family history of blood disorders or if you wear contact lenses. Patients should also inform if they are pregnant, breast-feeding or having any allergies. Consult your doctor if you experience anything different.
Q: Can OPTICHLOR P EYE DROPS be used during pregnancy?
A: OPTICHLOR P EYE DROPS is not recommended for use during pregnancy as the safety of one of its ingredients in pregnancy has not been established and it may be absorbed in blood and cross the placenta. If you are pregnant, think you may be pregnant or planning to get pregnant, consult your doctor before using this medicine. Inform your doctor immediately if you become pregnant during management with OPTICHLOR P EYE DROPS.
References
1. KD. Tripathi. Antimicrobials: General Considerations. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 689.
2. Kiran, Mayuresh & Sheikh, Shaheen & Pawaskar, Lalit. Study to Determine the Safety and Efficacy of Combination of Chloramphenicol and Polymyxin-B in Ocular Bacterial Infection. Research Gate. January 2019. [Accessed on 19th July 2022] https://www.researchgate.net/publication/331223177_STUDY_TO_DETERMINE_THE_SAFETY_AND_EFFICACY_OF_COMBINATION_OF_CHLORAMPHENICOL_AND_POLYMYXIN-B_IN_OCULAR_BACTERIAL_INFECTION
3. Centaur Pharmaceuticals Pvt. Ltd. and DCI Pharmaceuticals. Chloramphenicol + Polymyxin B. [Accessed on 19th July 2022] https://www.centaurpharma.com/downloads/2022/ophthalmology/anti-infectives/Ocupol%20Eye%20drops%20Ointment.pdf
4. Pharmtak Ophthalmics (I) Pvt. Ltd. Chloramphenicol + Polymyxin B. [Accessed on 19th July 2022] https://www.pharmtakindia.com/product/takchlor-eye-ear-oint/
Useful Diagnostic Tests
- Tympanometry
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