ONE 72 PILL Tablet 1's

Introduction About ONE 72 PILL TABLET

ONE 72 PILL TABLET contains Levonorgestrel, which belongs to the group of medicines called Emergency Contraceptives. It is used to manage pregnancy. It is recommended for use by women only in the event of an emergency following an event of unprotected sexual intercourse, or failure of birth control measures. However, it is not recommended for regular usage as a contraceptive.

ONE 72 PILL TABLET is not recommended for use in patients with severe liver problems, Crohn’s disease (an inflammatory small bowel disease), a history of ectopic pregnancy (a condition where the baby develops elsewhere outside of the womb), salpingitis (inflammation of the fallopian tubes), thrombosis (blood clotting), or serious digestive problems.

ONE 72 PILL TABLET is not recommended for use in pregnant women, as it does not terminate the pregnancy. ONE 72 PILL TABLET should be used with caution in breastfeeding mothers as it may pass through breast milk. Avoid nursing your baby for the next 8 hours after taking ONE 72 PILL TABLET and your doctor may also recommend draining the breast milk (before nursing your baby) after taking this medicine. ONE 72 PILL TABLET is not recommended for use by children who have not attained puberty.

The most common side effects of taking ONE 72 PILL TABLET are nausea, irregular bleeding until the next menstrual cycle, lower abdominal pain, tiredness, headache, vomiting, tender breasts, diarrhoea, and feeling dizzy. Contact your doctor immediately if any of your symptoms get worse or persist.

Uses Of ONE 72 PILL TABLET

• To manage pregnancy

How ONE 72 PILL TABLET Works

ONE 72 PILL TABLET works by managing the release and fertilization (when sperm unite with an egg) or of the egg from the ovary, or by managing the attachment of a fertilized egg to the uterus (implantation).

How to use ONE 72 PILL TABLET

Take ONE 72 PILL TABLET as advised by your physician. Take ONE 72 PILL TABLET within 72 hours after unprotected sexual intercourse. Swallow the medicine with water and do not crush or chew the medicine.

Side Effects Of ONE 72 PILL TABLET

How To Manage Side Effects

Diarrhea

Drink plenty of water and fruit juice, to keep yourself hydrated. Contact your doctor if the symptom does not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Contact your doctor if the symptom does not improve

Headache

Rest and relax. If necessary, apply a pain-relieving balm to your forehead. Contact your doctor if the headache does not improve.

Nausea And Vomiting

Take the medicine with or just after a meal. Stick to simple meals. Avoid eating oily or spicy foods. If your symptom gets worse or persist, consult your doctor immediately.

Stomach Pain

Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. If your symptom gets worse or persist, consult your doctor immediately.

Warning & Precautions

Pregnancy

Contraindicated

ONE 72 PILL TABLET is not recommended for use by pregnant women. ONE 72 PILL TABLET does not help to terminate the pregnancy. If you happen to get pregnant after taking ONE 72 PILL TABLET, contact your doctor immediately.

Breastfeeding

Use with Caution

ONE 72 PILL TABLET should be used with caution in breastfeeding mothers as it may pass through breast milk. Avoid nursing your baby for the next 8 hours after taking this medicine. Your doctor may also recommend draining the breast milk (before nursing your baby) after taking this medicine. Contact your doctor before taking ONE 72 PILL TABLET.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if you feel tired or dizzy after taking ONE 72 PILL TABLET.

Liver

Contraindicated

ONE 72 PILL TABLET is not recommended for use in patients with severe liver disease or liver cancer. Contact your doctor before taking ONE 72 PILL TABLET.

Allergy

Contraindicated

Do not take ONE 72 PILL TABLET if you are allergic (hypersensitive) to levonorgestrel or have an intolerance to lactose or other ingredients in this medicine.

Lungs

Contraindicated

ONE 72 PILL TABLET is not recommended for use in patients with lung disease, such as pulmonary embolism (blood clots in the lung). Contact your doctor before taking ONE 72 PILL TABLET.

Heart Disease

Contraindicated

GBNKEYWORD] is not recommended for use in patients with heart diseases, such as myocardial infarction and angina. Contact your doctor before taking ONE 72 PILL TABLET.

Interactions

A. Drug-Drug interactions:

Before taking ONE 72 PILL TABLET, inform your doctor if you are taking any of the following medicine:

• barbiturates and other medicines used to manage epilepsy (Ex. phenytoin, primidone, carbamazepine, oxcarbazepine, topiramate and felbamate)
• medicines used to manage tuberculosis (Ex. rifabutin, rifampicin)
• medicines used to manage HIV (Ex. ritonavir, efavirenz)
• medicine used to manage fungal infections (Ex. griseofulvin)
• St John’s wort (a medicine used for depression)
• cyclosporin (a medicine used to suppress the immune system)
• ulipristal acetate (a medicine used to manage uterine fibroids)
• medicine used to manage fungal infections (Ex. griseofulvin)
• bosentan (medicines used to manage pulmonary arterial hypertension)

Overdosage:

If you or anyone else has accidentally taken too much of ONE 72 PILL TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include vomiting (being sick), nausea, vaginal bleeding, etc.

Synopsis

More Information

• Keep ONE 72 PILL TABLET out of the sight and reach from children
• Store ONE 72 PILL TABLET below 25°C

FAQs About ONE 72 PILL TABLET

What is ONE 72 PILL TABLET used for?

ONE 72 PILL TABLET is used as an emergency contraceptive to manage pregnancy after unsafe sexual intercourse (such as failure of contraceptives or taking birth control measures). It should be used within 72 hours after having unprotected sexual intercourse, and it would be effective if you took this medicine within 12 hours rather than delay. It is not recommended to use this medicine as a regular birth control measure.

How does ONE 72 PILL TABLET work?

ONE 72 PILL TABLET works by managing the release and fertilization (when sperm unite with an egg) or of the egg from the ovary, or by managing the attachment of a fertilized egg to the uterus (implantation).

Can ONE 72 PILL TABLET affect my menstrual cycle?

ONE 72 PILL TABLET can affect your regular menstrual cycle. If you experience a delay or irregular menstrual bleeding, consult your doctor immediately.

What are the side effects of taking ONE 72 PILL TABLET?

The most common side effects of taking ONE 72 PILL TABLET are nausea, irregular menstrual bleeding till your next cycle, lower abdominal pain, tiredness, headache, vomiting, tender breasts, diarrhoea, and feeling dizzy. Contact your doctor if your symptoms get worse or persist.

How often can you use ONE 72 PILL TABLET?

ONE 72 PILL TABLET is not recommended for regular use. It is less effective and more likely to disturb your menstrual cycle if ONE 72 PILL TABLET is used more than once throughout a menstrual cycle (period).

References

1. K D Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. 7th edition. 2013. Page – 322.

2. Christina Vrettakos, Tushar Bajaj. Levonogestrel. National Institute of Health. NLM. National Centre for Biotechnology Information. Stat Pearls. May 2022. [Accessed on 6th August 2022] https://www.ncbi.nlm.nih.gov/books/NBK539737/

3. Lupin Healthcare (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 6th August 2022] https://www.medicines.org.uk/emc/files/pil.7308.pdf

4. Delpharm lille SAS. Health Products Regulatory Authority (HPRA). [Revised in June 2017] [Accessed on 6th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/PIL-2194006-28062017105522-636342441250781250.pdf

5. Gedeon Richter, Ltd. U.S. Food & Drug Administration. [Revised in July 2009] [Accessed on 6th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021998lbl.pdf

6. Laboratorios León Farma S.A. Levonorgestrel. [Revised in December 2019] [Accessed on 6th August 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=626a2333-ff56-ef28-a287-b33bacc0302a&type=display

4. Mylan Laboratories Limited. Levonorgestrel. [Revised in February 2017] [Accessed on 6th August 2022] https://extranet.who.int/pqweb/sites/default/files/RH031part3v1.pdf

5. HLL Lifecare Limited. Levonorgestrel. [Revised in July 2018] [Accessed on 6th August 2022] https://extranet.who.int/pqweb/sites/default/files/RH065part3v1.pdf

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 28 Jan 2023 | 02:10 PM(IST)