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Introduction About ONDITREX 4 TABLET
ONDITREX 4 TABLET is used to provide relief from sensation of nausea and vomiting. It contains a medicine called Ondansetron which is an anti-emetic medicine. It reduces the nausea and vomiting sensation by blocking the vomiting centres of the brain.
Before taking ONDITREX 4 TABLET, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium and magnesium or if you have been scheduled for any surgery.
Consult your doctor before taking ONDITREX 4 TABLET if you are pregnant or breastfeeding.
The dose of ONDITREX 4 TABLET will depends on the age, body weight and disease condition of your child. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking ONDITREX 4 TABLET.
The most common side effects of taking ONDITREX 4 TABLET includes headache, flushing and constipation. Consult your doctor if any of these above symptoms gets worse.
Uses Of ONDITREX 4 TABLET
- Management of nausea and vomiting
How ONDITREX 4 TABLET Works
ONDITREX 4 TABLET is anti-emetic medicine which works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and vomiting. Specifically, it targets the 5-HT3 receptors in the brain and the gastrointestinal tract. By inhibiting these receptors, ondansetron effectively reduces the signals that lead to nausea and vomiting, providing relief to patients undergoing treatments that can induce these symptoms.
How to use ONDITREX 4 TABLET
Take ONDITREX 4 TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow ONDITREX 4 TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.
For Oral Disintegrating strips: Place the medicine directly on your tongue and allow it to dissolve. For fast-dissolving strips, place the strip on your tongue or the inside of your cheek.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
Side Effects Of ONDITREX 4 TABLET
Common Side Effects of ONDITREX 4 TABLET:
- headache
- flushing (feeling of warmth)
- constipation
- Dizziness
- Diarrhea
Warning & Precautions
Pregnancy
Consult your doctorPregnant women should only use ONDITREX 4 TABLET if prescribed by a doctor, after assessing the benefits and risks.
Breastfeeding
Consult your doctorLimited data is available on the use of ondansetron during breastfeeding. While no harmful effects have been reported in breastfed infants, ondansetron is excreted in breast milk. Therefore, breastfeeding mothers should consult a doctor before using this medicine as a precaution.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy or uneasy after taking ONDITREX 4 TABLET.
Liver
Use with CautionONDITREX 4 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking ONDITREX 4 TABLET.
Allergy
ContraindicatedDo not take ONDITREX 4 TABLET if you are allergic to ondansetron, granisetron or palonosetron or to any other ingredients of this medicine.
Heart Disease
Use with CautionONDITREX 4 TABLET should be used with caution in patients with heart diseases such as uneven heartbeats (arrhythmias) or congestive heart failure.
Use In Pediatrics
Monitoring requiredONDITREX 4 TABLET can be used in children if prescribed by the physician.
Use In Geriatrics
Monitoring requiredONDITREX 4 TABLET can be used in elderly patients if prescribed by the physician.
Others
Before taking ONDITREX 4 TABLET, inform your doctor if you:
- have a blockage in your gut
- have problems with the levels of salts in the blood (such as potassium, sodium and magnesium)
- are intolerant to some sugars (Ex. lactose intolerance)
Interactions
A. Drug-Drug Interactions:
Before taking ONDITREX 4 TABLET, inform your doctor, if you are taking any of the following medicine:
- apomorphine (used to manage Parkinson’s disease)
- Antiepileptics (Ex. phenytoin, carbamazepine)
- Anti-TB agent (Ex. rifampicin)
- Pain killers (such as tramadol, methadone)
- Antipsychotic agents (Ex. haloperidol)
- Cardiac agents (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
- cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab)
- Antibiotics (such as erythromycin, ketoconazole)
- Antidepressants, Sedatives, Anxiolytics (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)
Overdosage:
If you or anyone else accidentally takes too much of ONDITREX 4 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ondansetron |
| Pharmacological Category | : | Serotonin antagonist |
| Therapeutic Indication | : | Nausea and Vomiting |
| Dosage Forms | : | Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille |
FAQs About ONDITREX 4 TABLET
Q: Is ONDITREX 4 TABLET a chemo drug?
A: No, it is not a chemo drug. It belongs to a group of medicines called serotonin antagonists and used to manage side effects caused due to chemotherapy.
Q: What ONDITREX 4 TABLET is used for?
A: ONDITREX 4 TABLET is used to manage nausea and vomiting caused by medical managements like chemotherapy, radiotherapy or surgery.
Q: For how long should you take ONDITREX 4 TABLET?
A: Your doctor will advise you on how long you should continue to take ONDITREX 4 TABLET. Consult your doctor from time to time to review your management and assess your symptoms.
Q: What happens if you take more ONDITREX 4 TABLET than your required dose?
A: If you or anyone else accidentally takes too much of ONDITREX 4 TABLET, consult your doctor immediately or visit the nearby hospital.
Q: What side effects are seen with ONDITREX 4 TABLET?
A: The most common side effects of taking ONDITREX 4 TABLET are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.
References
1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.
2. LTS Lohmann Therapie-Systeme AG Lohmannstrasse. Andernach GERMANY [Revised April 2022] [Accessed on 29 September 2022] click here
3. Koland M, Sandeep V, Charyulu N. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. J Young Pharm. 2010 Jul;2(3):216-22. [Accessed on 29 September 2022] click here
4. Kumria R, Gupta V, Bansal S, Wadhwa J, Nair AB. Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig. 2013 Apr;3(2):112-8. [Accessed on 29 September 2022] click here
5. Ondansetron Soluble Films. [Accessed on 29 September 2022] click here
6. Myoclinic. [Accessed on 29 September 2022] click here
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