ONDIPHAR Syrup 30ml

Introduction About ONDIPHAR SYRUP

ONDIPHAR SYRUP contains Ondansetron which belongs to a group of medicines called Anti-emetics. ONDIPHAR SYRUP is used to manage nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery.

Before giving ONDIPHAR SYRUP, to your child, inform your doctor if your child have or had severe constipation, heart problems, liver, kidney problems, imbalance with the levels of salts in your blood, (potassium, sodium, and magnesium), or have been scheduled for any surgery. During the therapy, your doctor would regularly monitor your child’s health to avoid the risk of side effects.

Your doctor will prescribe the right dose and duration depends on the child’s age, body weight and health condition, so stick to the dose, time, and duration prescribed by the doctor.  Minor and temporary side effects may be experienced after the intake of this medicine. These includes headache, flushing and constipation.

Generally, these effects subside once the child’s body adapts to the medicine. However, in case of prolonged or bothersome events, consult your doctor immediately without any delay. Inform your doctor about your child’s complete medical history including any previous episodes of allergies.

Uses Of ONDIPHAR SYRUP

• Used to manage nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery

How ONDIPHAR SYRUP Works

ONDIPHAR SYRUP is a serotonin 5-HT3 receptor antagonist (specific chemical receptor), and it works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

How to use ONDIPHAR SYRUP

Always give this ONDIPHAR SYRUP to your child as instructed by your doctor. Shake well before use. It is for pediatric use. Your doctor will prescribe the right dose depends on your child’s age body weight and disease condition.

Side Effects Of ONDIPHAR SYRUP

How To Manage Side Effects

Headache:

Give plenty of water and apply a wet or cold cloth on child’s forehead. Apply pain balm to head to ease off the pain. If there is no improvement in the symptom, contact your doctor.

Constipation:

Give more fiber-rich foods like green leafy vegetables and fruits. Give lots of water. If there is no improvement in the symptom, contact your doctor.

Warning & Precautions

Driving and Using Machines

Do not allow your child drive or play outdoors, as ONDIPHAR SYRUP may cause dizziness or blurry vision. Consult your doctor before giving ONDIPHAR SYRUP.

Kidney

ONDIPHAR SYRUP should be used with caution if the child has kidney disease. Consult your doctor before giving ONDIPHAR SYRUP.

Liver

ONDIPHAR SYRUP should be used with caution if the child has liver disease. Consult your doctor before giving ONDIPHAR SYRUP.

Allergy

Do not use ONDIPHAR SYRUP if your child is allergic (hypersensitive) to Ondansetron or any other ingredients of this medicine.

Heart Disease

ONDIPHAR SYRUP should be used with caution if your child has any heart disease. If needed, dose will be adjusted accordingly. Consult your doctor for advice.

Interactions

A. Drug-Drug Interactions:

Before using ONDIPHAR SYRUP, inform your doctor if your child is taking any of the following medicine:

• medicines used to manage fits/epilepsy (ex. phenytoin, carbamazepine)
• medicines used to manage lung infections (ex. rifampicin)
• tramadol (used to manage severe pain)
• medicines used to manage heart problems such as abnormal heart beats (anti-arrhythmic   ex. amiodarone)  
• cancer medicines (ex. doxorubicin, daunorubicin and monoclonal, trastuzumab) 
• medicines used to manage infections (erythromycin, ketoconazole)

Overdosage:

If your child accidentally takes too much of ONDIPHAR SYRUP, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep the medicine out of reach in children
• Store ONDIPHAR SYRUP at room temperature

FAQs About ONDIPHAR SYRUP

Q: What ONDIPHAR SYRUP is used for?

A: ONDIPHAR SYRUP is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give ONDIPHAR SYRUP to your child to manage vomiting post-procedure.

Q: What if my child takes too much ONDIPHAR SYRUP?

A: ONDIPHAR SYRUP is unlikely to cause harm if you give an extra dose by mistake. However, you must still tell your child’s doctor immediately.

Q: Can other medicines be given at the same time as ONDIPHAR SYRUP?

A: ONDIPHAR SYRUP may interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting ONDIPHAR SYRUP. Also, check with your child’s doctor before giving any medicine to your child.

Q: For how long should I give ONDIPHAR SYRUP?

A: Your doctor might advise you on how long your child should continue to take ONDIPHAR SYRUP. You will need to consult your doctor from time to time to review the child’s management and assess the symptoms.

Q: What are the side effects are seen with ONDIPHAR SYRUP?

A: The most common side effects include ONDIPHAR SYRUP are headache, flushing (feeling of warmth), constipation. Consult your doctor if the above side effects persist for a long time.

References

1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.

2. Alexandria Griddine, Jeffery S. Bush. Ondansetron Book from Stat Pearls Publishing, Treasure Island (FL), 16 May 2018 PMID: 29763014. [Revised on September 2021] [Accessed on 21st June 2022] https://europepmc.org/article/nbk/nbk499839

3. Apollo Pharma Ltd, Unit 1, Irwell Works, Lower Woodhill Road, Bury, BL8 1AA, UK, PL 14308/0015 [ Revised on June 20] [Accessed on 21st June 20221] https://www.medicines.org.uk/emc/files/pil.6049.pdf

4. Leeford. [Accessed on 21st June 20221] https://www.leeford.in/product/145/vomishield-drops

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 21 Jan 2023 | 09:28 AM(IST)