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Introduction About ONDEM SYRUP
ONDEM SYRUP is used to manage nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery. It contains Ondansetron, which belongs to a group of medicines called Anti-emetics.
Before giving ONDEM SYRUP to your child, inform your doctor if your child has or has had severe constipation, heart problems, liver and kidney problems, an imbalance with the levels of salts in your blood (potassium, sodium, and magnesium), or has been scheduled for any surgery. During the therapy, your doctor would regularly monitor your child’s health to avoid the risk of side effects.
Your doctor will prescribe the right dose and duration depending on the child’s age, body weight, and health condition, so stick to the dose, time, and duration prescribed by the doctor. Minor and temporary side effects may be experienced after the intake of this medicine. These include headaches, flushing, and constipation.
Generally, these effects subside once the child’s body adapts to the medicine. However, in cases of prolonged or bothersome events, consult your doctor immediately, without any delay. Inform your doctor about your child’s complete medical history, including any previous episodes of allergies.
Uses Of ONDEM SYRUP
- To manage nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery
How ONDEM SYRUP Works
ONDEM SYRUP is a serotonin 5-HT3 receptor antagonist (specific chemical receptor), and it works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
How to use ONDEM SYRUP
Always give this ONDEM SYRUP to your child as instructed by your doctor. Shake well before use. It is for pediatric use. Your doctor will prescribe the right dose depending on your child’s age, body weight, and disease condition.
Side Effects Of ONDEM SYRUP
Common
- Headache
- Constipation
- Weakness
- Tiredness
- Chills and drowsiness
Rare
Stop giving ONDEM SYRUP and contact your doctor immediately if your child experiences any of the following side effects:
- A severe allergic reaction may include a red and lumpy skin rash (hives), difficulty breathing, sudden wheezing, swelling of the face, mouth, lips, or eyelids, or a high temperature (fever).
How To Manage Side Effects
Constipation
Give more fiber-rich foods like green leafy vegetables and fruits. Give lots of water. If there is no improvement in the symptom, contact your doctor.
Headache
Give plenty of water and apply a wet or cold cloth to the child’s forehead. Apply pain balm to the head to ease off the pain. If there is no improvement in the symptom, contact your doctor.
Warning & Precautions
Driving and Using Machines
ContraindicatedDo not allow your child to drive or play outdoors, as ONDEM SYRUP may cause dizziness or blurry vision. Consult your doctor before giving ONDEM SYRUP.
Kidney
Use with CautionONDEM SYRUP should be used with caution if the child has kidney disease. Consult your doctor before giving ONDEM SYRUP.
Liver
Use with CautionONDEM SYRUP should be used with caution if the child has liver disease. Consult your doctor before giving ONDEM SYRUP.
Allergy
ContraindicatedDo not use ONDEM SYRUP if your child is allergic (hypersensitive) to Ondansetron or any other ingredients in this medicine.
Heart Disease
Use with CautionONDEM SYRUP should be used with caution if your child has any heart disease. If needed, the dose will be adjusted accordingly. Consult your doctor for advice.
Use In Pediatrics
Consult your doctorYour doctor will prescribe the right dose and frequency, depending on your child’s age, body weight, and disease condition. Consult your doctor before giving ONDEM SYRUP.
Others
Before giving ONDEM SYRUP, inform your doctor if your child had or has:
- Problems with the levels of salts in the blood, such as potassium, sodium, and magnesium
- Severe constipation or gut problems like blockage
- Are intolerant to some sugars (Ex. fructose intolerance)
Interactions
A. Drug-Drug Interactions:
Before using ONDEM SYRUP, inform your doctor if your child is taking any of the following medicines:
- Anticonvulsants (Ex. phenytoin, carbamazepine)
- Antimycobacterial agent (Ex. rifampicin)
- Opioid analgesic (Ex. tramadol)
- Anti-arrhythmic (Ex. amiodarone)
- Anti-cancer medicines (Ex. doxorubicin, daunorubicin, and monoclonal trastuzumab)
- Antibiotics (Ex. erythromycin)
- Antifungal (Ex ketoconazole)
Overdosage:
If your child accidentally takes too much of ONDEM, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ondansetron |
| Pharmacological Category | : | Serotonin antagonist |
| Therapeutic Indication | : | Nausea and vomiting in patients (undergoing chemotherapy, radiotherapy, or surgery) |
| Dosage Forms | : | Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral Strips, Lozenges, Pastille |
More Information
Storage
- Keep ONDEM out of reach of children
- Store ONDEM at room temperature
FAQs About ONDEM SYRUP
Q: What is ONDEM SYRUP used for?
A: ONDEM SYRUP will be given to children to manage nausea and vomiting before any major surgery or before chemotherapy or radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give ONDEM SYRUP to your child to manage vomiting post-procedure.
Q: What if my child takes too much of ONDEM?
A: ONDEM is unlikely to cause harm if you give an extra dose by mistake. However, you must tell your child’s doctor immediately.
Q: Can other medicines be given at the same time as ONDEM SYRUP?
A: ONDEM SYRUP may interact with other medicines. Tell your doctor about any other medicines your child is taking before starting ONDEM SYRUP. Check with your child’s doctor before giving any medicine to your child.
Q: For how long should I give ONDEM SYRUP?
A: Your doctor might advise you on how long your child should continue to take ONDEM SYRUP. You will need to consult your doctor from time to time to review the child’s management and assess the symptoms.
Q: What are the side effects seen with ONDEM SYRUP?
A: The most common side effects of ONDEM SYRUP are headaches, flushing (a feeling of warmth), or constipation. Consult your doctor if any of the above side effects persist for a long duration.
Q: Can ONDEM SYRUP be given three times a day?
A: ONDEM SYRUP can be given twice daily or three times daily if it is prescribed by your doctor. Consult your doctor for advice.
Q: What precautions must be taken while using ONDEM SYRUP?
A: ONDEM SYRUP should be used with caution if the child has liver disease, kidney disease, and heart disease; has problems with the levels of salts in the blood, such as potassium, sodium, and magnesium; has severe constipation or gut problems like blockage; or is intolerant of some sugars (Ex. fructose intolerance). Consult your doctor before giving ONDEM SYRUP.
Q: How long does the effect of ONDEM SYRUP last?
A: ONDEM SYRUP usually controls nausea and vomiting for as long as 8 hours. Consult your doctor for advice before giving the medicine to your child.
Q: How does ONDEM SYRUP work?
A: ONDEM SYRUP is used for nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. This medicine works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
Q: How should I buy ONDEM SYRUP from an online pharmacy?
A: If you wish to buy ONDEM SYRUP on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.
References
1. KD. Tripathi. Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.
2. Alexandria Griddine, Jeffery S. Bush. Ondansetron. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2023. PMID: 29763014. [Accessed on 13th April 2024] https://europepmc.org/article/nbk/nbk499839
3. Pharmadox Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2023] [Accessed on 13th April 2024] https://www.medicines.org.uk/emc/files/pil.8945.pdf
4. Ondansetron Oral Solution. Leeford Healthcare Ltd. [Accessed on 13th April 2024] https://www.leeford.in/product/145/vomishield-drops
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