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Macleods Pharmaceuticals Pvt Ltd

Omnacortil 10mg Tablet 10'S

Hormonal Therapy
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    Introduction About OMNACORTIL 10MG TABLET

    OMNACORTIL 10MG TABLET is used in the management of inflammatory and auto-immune conditions such as allergies (including severe allergic reactions), inflammation (affecting the lungs, including asthma, blood vessels, heart, bowel, and kidneys), muscles and joints, including rheumatoid arthritis, and the eye and nervous system), skin conditions, infections, and cancers (such as leukemia, lymphoma, and myeloma).

    OMNACORTIL 10MG TABLET is also used to manage organ rejection after transplantation and, in some cases, to boost steroid levels when the body is unable to produce natural steroids on its own. It is also used to manage high calcium levels in the affected individuals, which are generally characterized by symptoms such as stomach pain, nausea, bone pain, and muscle weakness. It contains Prednisolone, which belongs to a group of medicines called Corticosteroids, which help manage pain and inflammatory conditions.

    OMNACORTIL 10MG TABLET is not recommended for use in patients with fungal infections or in patients who have recently taken live vaccinations. Before taking OMNACORTIL 10MG TABLET, inform your doctor if you have an infection, an underactive thyroid gland (hypothyroidism), seizures (fits), myasthenia gravis (muscle weakness), diabetes, high blood pressure, heart failure, liver or kidney disease.

    OMNACORTIL 10MG TABLET should be used with caution in pregnant and breastfeeding women. It is also used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking the medicine. The most common side effects of taking OMNACORTIL 10MG TABLET are infection, signs of low potassium levels (such as constipation and a fast heartbeat), signs of increased sugar in the blood and urine (such as increased thirst and frequent urination), high blood pressure, thinner skin, and impaired wound healing. Consult your doctor before taking the medicine.

    Uses Of OMNACORTIL 10MG TABLET

    • To manage inflammatory and auto-immune conditions such as:
      • Allergies (including severe allergic reactions)
      • Inflammation (affecting the lungs, including asthma, blood vessels and heart, bowel and kidney, muscles and joints, including rheumatoid arthritis, and the eye and nervous system)
      • Skin conditions, infections, and cancers (such as leukemia, lymphoma, and myeloma)
    • To manage organ rejection after transplantation
    • To boost steroid levels when the body is unable to make enough natural steroids on its own. 
    • To manage high calcium levels in the body

    How OMNACORTIL 10MG TABLET Works

    Prednisolone works by blocking the production of polymorphonuclear leukocytes (immune cells responsible for inflammation and allergic reactions), which results in managing the occurrence of inflammatory and allergic reactions in the affected individuals, thus managing the conditions.

    How to use OMNACORTIL 10MG TABLET

    Take OMNACORTIL 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of OMNACORTIL 10MG TABLET depending upon your age, body weight, and disease conditions.

    Side Effects Of OMNACORTIL 10MG TABLET

    Common

    • Infections such as tuberculosis
    • Lower concentrations of certain hormones, Cushing’s-like appearance, and growth retardation in children
    • Signs of low levels of potassium, such as constipation, a fast heartbeat, fatigue, muscle damage, muscle weakness, or spasms
    • Signs of high sodium levels, such as confusion, muscle twitching, seizures, and coma
    • Signs of increased sugar in the blood and urine, such as increased thirst, frequent urination, and excessive hunger
    • Osteoporosis (weak and brittle bones)
    • Swelling due to fluid accumulation
    • High blood pressure
    • Thinner skin
    • Impaired wound healing
    • Muscle wasting

    Uncommon

    • Mental disorders (at high doses)
    • Cataracts, glaucoma (increased eye pressure with pain)

    Rare

    • Depression
    • Mania in patients without a history of psychiatric illness
    • Increased benign pressure in the skull
    • Breakdown of bone tissue
    • Tendon rupture

    Stop taking OMNACORTIL 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:

    • Signs of severe allergic reactions (including angioedema) such as swelling of the face, tongue, or throat, difficulty swallowing, hives, difficulty breathing, fever, or a drop in blood pressure
    • Signs of a pheochromocytoma crisis (a rare, life-threatening adrenal gland tumour) such as anxiety, headache, palpitations, sweating, and pale skin
    • Signs of acute renal and kidney crises (due to scleroderma), such as high blood pressure and decreased urine output
    • Suicidal thoughts
    • Exposure to people infected with chickenpox, shingles, and measles

    Warning & Precautions

    Pregnancy

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in pregnant women and in women planning for pregnancy. Consult your doctor before taking OMNACORTIL 10MG TABLET.

    Breastfeeding

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in breastfeeding women since the medicine may pass through milk. Consult your doctor before taking OMNACORTIL 10MG TABLET.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you experience visual disturbance, dizziness, or tiredness while taking OMNACORTIL 10MG TABLET. Consult your doctor before taking this medicine.

    Kidney

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in patients with kidney failure. Consult your doctor before taking the medicine.

    Liver

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in patients with liver disease. Consult your doctor before taking OMNACORTIL 10MG TABLET.

    Allergy

    Contraindicated

    Do not take OMNACORTIL 10MG TABLET if you are allergic to prednisolone or any other ingredient in this medicine.

    Heart Disease

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in patients with heart disease, such as heart failure. Consult your doctor before taking the medicine.

    Use In Pediatrics

    Use with Caution

    OMNACORTIL 10MG TABLET should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking it.

    Use In Geriatrics

    Use with Caution

    OMNACORTIL 10 MG TABLET should be taken with caution in elderly patients (above 65 years of age). Consult your doctor before taking it.

    Others

    OMNACORTIL 10MG TABLET is not recommended for use if you:

    • Have a fungal infection
    • Recently had any live vaccinations

    Before taking OMNACORTIL 10MG TABLET, inform your doctor if you have:

    • Or get an infection
    • An underactive thyroid gland (hypothyroidism)
    • Or had seizures
    • Myasthenia gravis (muscle weakness)
    • Or had been managed for tuberculosis
    • Gastric, duodenal ulcer, or inflammatory bowel disease such as ulcerative colitis or diverticulitis
    • Diabetes
    • High blood pressure
    • Or had blood clots, such as vein thrombosis
    • Mood swings or psychotic tendencies
    • Osteoporosis
    • Adrenal tumour (pheochromocytoma)
    • Surgically created new blood vessels or intestinal connections
    • Scleroderma (a rare auto-immune disease characterized by chronic hardening and tightening of the skin)
    • Intolerance to certain sugars, such as lactose

    Interactions

    A. Drug-drug interactions:

    • Antitubercular agents (Ex. rifampicin, isoniazid)
    • Blood thinners (Ex. warfarin)
    • Anticonvulsants (Ex. carbamazepine, phenobarbital, phenytoin)
    • Anticholinergics (Ex. trihexyphenidyl, benztropine, ipratropium, and tiotropium)
    • Cholinesterase inhibitors (Ex. neostigmine, edrophonium)
    • Antidiabetic (Ex. insulin, metformin, glipizide)
    • Anti-HIV agents (Ex. cobicistat)
    • Birth control pills (Ex. estrogens)
    • Non-steroidal anti-inflammatory medicines (Ex. acetylsalicylic acid, ibuprofen)
    • Diuretics (Ex. chlorothiazide, chlorthalidone, and furosemide)
    • Antiasthmatics (Ex. theophylline, salbutamol, terbutaline, salmeterol, and formoterol)
    • Antifungal (Ex. amphotericin B)

    Overdosage:

    If you or anyone else accidentally take too much of OMNACORTIL 10 MG TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Prednisolone
    Pharmacological Category :   Corticosteroids
    Therapeutic Indication :   Inflammatory and Auto-immune conditions, Organ rejection (after transplantation) and hypercalcemia
    Dosage Forms :   Tablet, Dispersible Tablet, Eye Drops, Ophthalmic Suspension, Oral Drops, Solution, Suspension, Syrup

    More Information

    Storage

    • Keep OMNACORTIL out of reach of children
    • Do not store OMNACORTIL above 25°C

    FAQs About OMNACORTIL 10MG TABLET

    Q: What is OMNACORTIL 10MG TABLET used for?

    A: OMNACORTIL 10MG TABLET is used to correct adrenal insufficiency and to manage various inflammatory and auto-immune conditions such as (allergic reactions, asthma, inflammation of blood vessels, heart muscle inflammation, inflammatory bowel diseases, kidney inflammation, muscles inflammation and joints inflammatory conditions (such as rheumatoid arthritis), inflammation of eye and nervous system, and autoimmune skin conditions. It can also be used to manage organ rejection after transplantation, boost steroid levels when the body is unable to make enough natural steroids on its own and manage calcium levels in the body.

    Q: Is OMNACORTIL 10MG TABLET a strong steroid?

    A: Yes, OMNACORTIL 10MG TABLET is considered a strong steroid. It contains the active ingredient prednisolone, which is a synthetic corticosteroid. Prednisolone is used to manage a variety of inflammatory and autoimmune conditions due to its potent anti-inflammatory and immunosuppressive effects. However, it also carries a risk of side effects, especially when used at higher doses or for prolonged periods. It's essential to use OMNACORTIL 10MG TABLET or any steroid medication exactly as prescribed by a healthcare professional and to follow their guidance closely to minimize the risk of adverse effects.

    Q: Does OMNACORTIL 10MG TABLET makes you sleepy?

    A: Yes, OMNACORTIL 10MG TABLET, which contains the active ingredient prednisolone, can cause drowsiness or sleepiness as a side effect in some individuals. While not everyone experiences this side effect, it is listed as a possible adverse reaction of the medication. Other common side effects of prednisolone may include insomnia (difficulty sleeping) or changes in mood or behavior. If you find that OMNACORTIL 10MG TABLET is causing significant drowsiness or any other concerning side effects, it's important to discuss them with your healthcare provider.

    Q: Is it safe to use OMNACORTIL 10MG TABLET?

    A: OMNACORTIL 10MG TABLET mg Tablet is safe and effective when used as prescribed by a healthcare professional. However, like all medications, OMNACORTIL 10MG TABLET carries potential risks and side effects, especially when used at higher doses or for prolonged periods. Some common side effects of prednisolone may include increased appetite, weight gain, fluid retention, changes in mood, insomnia, and gastrointestinal upset. Your doctor will prescribe the lowest effective dose for the shortest duration necessary to control your symptoms and minimize the risk of side effects.

    Q: How does OMNACORTIL 10MG TABLET work?

    A: OMNACORTIL 10MG TABLET contains the active ingredient prednisolone, which belongs to a class of medications known as corticosteroids. Prednisolone works by mimicking the actions of naturally occurring corticosteroid hormones produced by the adrenal glands in the body. Prednisolone has potent anti-inflammatory, immunosuppressive, and anti-allergic properties. It works by inhibiting the production of inflammatory substances in the body, such as prostaglandins and leukotrienes, and by suppressing the activity of certain immune cells involved in the inflammatory response.

    Q: What side effects are seen with the use of OMNACORTIL 10MG TABLET?

    A: The most common side effects of taking OMNACORTIL 10MG TABLET increased appetite, weight gain, fluid retention, leading to swelling in the extremities, mood changes, including irritability, anxiety, or depression, insomnia or changes in sleep patterns, gastrointestinal discomfort, such as stomach pain, nausea, or indigestion, increased susceptibility to infections due to suppression of the immune system, diabetes, osteoporosis with long-term use, skin changes, such as acne or thinning of the skin, cataracts or glaucoma with prolonged use.

    Q: Can OMNACORTIL 10MG TABLET be used in pregnant and breast-feeding woman?

    A: OMNACORTIL 10MG TABLET should be used with caution during pregnancy and by women planning for pregnancy. It should also be used with caution in breastfeeding women as the medicine may pass through milk. Consult your doctor before taking the medicine.

    Q: Can OMNACORTIL 10MG TABLET be given to children?

    A: OMNACORTIL 10MG TABLET should be used with caution in children and adolescents (below 18 years). Long term usage should be avoided. Your doctor will decide the dose, frequency and duration depending on the child’s age, body weight and disease conditions.

    Q: Can OMNACORTIL 10MG TABLET be used in patients with liver problems?

    A: OMNACORTIL 10MG TABLET should be used with caution in patients with liver disease. Consult your doctor before taking.

    Q: Can OMNACORTIL 10MG TABLET be used in patients with kidney problems?

    A: OMNACORTIL 10MG TABLET should be used with caution in patients with kidney failure. Consult your doctor taking the medicine.

    Q: Can OMNACORTIL 10MG TABLET be used in patients with heart problems?

    A: OMNACORTIL 10MG TABLET should be used with caution in patients with heart disease such as heart failure. Consult your doctor before taking the medicine.

    Q: What to do if I forgot to take a dose of OMNACORTIL 10MG TABLET?

    A: If you forgot to take a dose of OMNACORTIL 10MG TABLET, take it as soon as you remember. However, if it is time for the next dose of OMNACORTIL 10MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of OMNACORTIL 10MG TABLET to compensate the missed ones.

    Q: Can I stop taking OMNACORTIL 10MG TABLET without consulting your doctor?

    A: No. You should not stop taking OMNACORTIL 10MG TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using OMNACORTIL 10MG TABLET, consult your doctor for advice.

    Q: Can I drive after taking OMNACORTIL 10MG TABLET?

    A: Do not drive or operate any machines if you experience visual disturbance, dizziness or tiredness while taking OMNACORTIL 10MG TABLET. Consult your doctor before taking this medicine.

    User Feedback

    1. KD. Tripathi. Corticosteroids. Essentials of medical pharmacology. Eighth 8th edition. 2013. Page – 313.

    2. Yana Puckett; Aishah Gabbar; Abdullah A. Bokhari. Prednisone. NIH National Library of Medicine, National center for biotechnology information. StatPearls. May 2022. [Accessed on 13th April 2024] https://www.ncbi.nlm.nih.gov/books/NBK534809/

    3. Ciro Manzo, Jordi Serra-Mestres, Alberto Castagna, and Marco Isetta. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. August 2018. [Accessed on 13th April 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163472/

    4. Accord UK Ltd. Prednisolone. [Revised in January 2024] [Accessed on 13th April 2024]  https://accord-healthcare-products.co.uk/products/p/prednisolone-tablets

    5. Healing Pharma India Pvt. Ltd. Predniheal 40. [Accessed on 13th April 2024] https://www.healingpharma.in/product/predniheal-40/

    Useful Diagnostic Tests

    • Complete Blood Count (CBC)/ Hemogram
    • Peripheral Smear Examination
    • Kidney Function Test (KFT)
    • Liver Function Test (LFT)
    • Healthy Midlife Checkup
    • Men Health Checkup - Advanced
    • Complete Women Checkup
    • Senior Citizen Checkup – Female
    • Senior Citizen Checkup – Male
    • Women Health Checkup - Essential
    • Full Body Checkup - Gold
    • Elderly Checkup - Female
    • Elderly Checkup - Male
    • Full Body Checkup - Silver

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. M N Himaja - MBBS
    Last updated on 20 Apr 2024 | 05:11 PM(IST)
    Lab updated