Dr. Reddy's Laboratories Ltd

Olsertain 20mg Tablet 15'S

Hypertension
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    Introduction About OLSERTAIN 20MG TABLET

    Olmesar 20mg Tablet contains Olmesartan medoxomil, an angiotensin II receptor blocker (ARB) designed to help manage high blood pressure. By supporting vessel relaxation, it allows smoother blood flow and reduces heart workload. Regular use, as advised by a healthcare provider, fits into daily routines for ongoing blood pressure management.

    Olmesartan blocks the effects of angiotensin II, a substance that tightens blood vessels. This leads to vessel relaxation and improved circulation, helping to control blood pressure over time.

    Before taking Olmesar 20mg, inform your doctor if you have kidney, liver issues, or if you are pregnant or breastfeeding women. Avoid use with certain medicines and always review your current list with a healthcare provider.

    Your doctor may advice you to take regular exercise such as walking or swimming, low salt diet, giving up smoking and alcohol drinking, which helps to reduce blood pressure effectively during management with this medicine.

    If you experience dizziness or persistent side effects like headache or stomach pain, seek medical advice. Olmesar 20mg is not recommended for those with known allergies to its ingredients or during pregnancy without supervision.

    Uses Of OLSERTAIN 20MG TABLET

    Benefits of OLSERTAIN 20MG TABLET

    • Helps maintain healthy blood pressure levels
    • Supports heart and kidney health
    • Fits easily into most treatment routines
    • May reduce risk of heart-related complications related to high blood pressure

    How OLSERTAIN 20MG TABLET Works

    Olmesar 20mg Tablet supports blood pressure control primarily by blocking the vasoconstrictive effects of angiotensin II, a hormone that normally narrows blood vessels. Olmesartan selectively binds to angiotensin type 1 (AT1) receptors on vascular smooth muscle and adrenal glands. By managing angiotensin II from binding to these receptors, Olmesar causes blood vessels to relax (vasodilation), reducing the resistance against which the heart must pump and thereby lowering blood pressure. This competitive inhibition of AT1 receptors also reduces aldosterone secretion, which decreases sodium and water retention, further helping in blood pressure regulation.

    The physiological effects of Olmesar contribute not only to lowering blood pressure but also to improving heart and kidney function by decreasing the workload on these organs. Clinical data show that Olmesar exhibits a rapid onset of action, with significant blood pressure reduction often observed within two weeks of treatment.

    How to use OLSERTAIN 20MG TABLET

    • Take one tablet daily, at the same time each day
    • Can be taken with or without food
    • Swallow whole with water, do not crush or chew
    • Consistency is key; continue as advised by your doctor

    Recommended Dosage for Olmesar 20mg

    • The usual starting dose for adults is 20 mg once daily, with or without food. Your healthcare provider may increase the dose as needed for optimal blood pressure control, but the usual maximum is 40 mg once daily.
    • Take it at the same time each day to help maintain consistent blood levels and therapeutic effect.
    • In elderly patients or those with kidney/liver impairment, dosage may need adjustment and regular medical supervision is advised.

    Changes in Lifestyle to Support Olmesar Therapy

    • Engage in regular physical activity such as walking, swimming, or cycling
    • Follow a balanced, low-sodium diet and maintain a healthy body weight
    • Limit alcohol intake and avoid smoking for added cardiovascular support
    • Adhere to other physician-recommended lifestyle modifications to complement your medication regimen

    What if I forgot to take OLSERTAIN 20MG TABLET

    • Take the missed dose as soon as you remember, unless it is almost time for your next dose, in that case, skip the missed dose and resume your normal schedule.
    • Do not double the dose to make up for the missed tablet
    • Return to your routine and inform your healthcare provider if you miss doses frequently

    Overdose

    If you or anyone else accidentally takes too much of Olmesar 20mg Tablet, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms are low blood pressure, fast heart rate, slow heart rate (bradycardia) if vagal nerve stimulation occurs.

    Side Effects Of OLSERTAIN 20MG TABLET

    Common Side Effects of OLMESAR 20MG TABLET

    • dizziness
    • headache
    • stomach pain

    When to consult a doctor?

    • allergic reactions (signs include swelling of the face, mouth and/or larynx (voice box), itching and rash)

    Managing Side Effects While Taking Olmesar 20mg Tablet

    Managing side effects while taking Olmesar 20mg Tablet involves awareness, self-monitoring, and timely medical consultation when needed. Most common side effects such as dizziness, headache, tiredness, stomach upset, diarrhea, nausea, sore throat, or flu-like symptoms tend to be mild and often resolve as your body adjusts to the medicine. To reduce dizziness or lightheadedness, especially when standing up quickly, rise slowly from a seated or lying position and stay well-hydrated.

    Warning & Precautions

    Pregnancy

    Contraindicated

    Olmesar 20mg is not recommended during pregnancy without consulting the health care provider.

    Breastfeeding

    Consult your doctor

    Before taking Olmesar 20mg, inform your doctor if you are a breastfeeding women.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you feel dizzy or sleepy after taking Olmesar 20mg.

    Kidney

    Consult your doctor

    Before taking Olmesar 20mg, inform your doctor if you have kidney problems.

    Liver

    Consult your doctor

    Before taking Olmesar 20mg, inform your doctor if you have liver problems.

    Allergy

    Contraindicated

    Do not take Olmesar 20mg if you are allergic to Olmesartan or any other ingredients of this medicine.

    Heart Disease

    Use with Caution

    Olmesar 20mg should be taken with caution in patients with heart failure or problems with heart valves or heart muscles.  

    Use In Pediatrics

    Consult your doctor

    Olmesar 20mg is not recommended for use in children below 6 years of age. Your child’s doctor may adjust the dose based on the body weight of the child.

    Use In Geriatrics

    Use with Caution

    Olmesar 20mg should be used with caution in elderly patients (aged 65 years and above)

    Other Warnings for OLSERTAIN 20MG TABLET

    Before taking Olmesar 20mg, inform your doctor if you:

    • have severe vomiting, diarrhoea
    • are on a low salt diet
    • have problems with adrenal glands
    • have increased levels of potassium in the blood

    Who should not take OLSERTAIN 20MG TABLET

    Olmesar 20mg is not recommended for use if you:

    • problems with the drainage of the bile from the gallbladder

    Diet and Lifestyle Advice

    • Take Olmesar 20mg Tablet once daily, ideally at the same time every day (such as with breakfast or dinner) for consistency and best results.
    • You may take the tablet with or without food, based on your preference and doctor’s advice.
    • Pair the medication with blood pressure monitoring at home, noting values regularly in a logbook or digital tracker.
    • Follow a nutritious, low-sodium diet with fresh fruits, vegetables, whole grains, and lean proteins while minimizing processed foods and added salt.
    • Engage in moderate physical activity such as brisk walking, cycling, or swimming at least 30 minutes most days of the week to enhance overall cardiovascular health.
    • Limit or avoid alcohol and quit smoking to further reduce cardiovascular risks and enhance medication effectiveness.
    • Stay well-hydrated and rise slowly from sitting or lying down to help manage dizziness, especially when starting Olmesar.
    • Keep regular medical appointments for blood pressure, kidney function, and electrolyte monitoring as advised by your healthcare provider.
    • Do not stop Olmesar suddenly or adjust your dose without medical consultation; if you miss a dose, take it soon as remembered unless near the next scheduled dose, never double up.

    Drug - Drug interaction

    Drug Interactions to Know When Taking Olmesar 20mg Tablet

    • Avoid using Olmesar with ACE inhibitors (e.g., enalapril, lisinopril, ramipril), especially in patients with diabetes or kidney impairment, as there is increased risk of kidney damage, high potassium, and low blood pressure.
    • Do not take Olmesar with aliskiren if you have diabetes or kidney issues, since the combination raises risk of serious cardiovascular and renal events.
    • Combining Olmesar with potassium supplements, salt substitutes containing potassium, or potassium-sparing diuretics (e.g., spironolactone, amiloride) may result in dangerously high blood potassium levels.
    • Concomitant use with diuretics (e.g., furosemide, hydrochlorothiazide, spironolactone) can enhance blood pressure lowering but may also increase side effects like low blood pressure or dehydration.
    • Non-steroidal anti-inflammatory drugs (NSAIDs, e.g., ibuprofen, naproxen) may reduce the effectiveness of Olmesar and increase risk of kidney problems, especially in elderly patients.
    • Lithium should not be used alongside Olmesar due to possible toxic accumulation and side effects.
    • Cholesterol-lowering drugs such as colesevelam should be taken at least 4 hours before Olmesar to avoid reduced absorption.
    • Some antibiotics (e.g., rifampicin, erythromycin, clarithromycin), antifungals (e.g., ketoconazole, itraconazole), antiviral agents (e.g., ritonavir), and immunosuppressants may increase Olmesar blood levels, dose adjustment may be needed.
    • St. John’s Wort, anti-manic agents such as lithium, certain skeletal muscle relaxants, and calcium-channel blockers may interact with Olmesar and alter its effects or increase risks.
    • Always inform your physician of all prescription medicines, over-the-counter drugs, supplements, and herbal products you use to screen for possible interactions and adjust therapy as required

    Synopsis

    Drug :   Olmesartan
    Pharmacological Category :   Angiotensin Receptor Blockers
    Therapeutic Indication :   Hypertension
    Dosage Forms :   Tablet

    More Information

    Link to related products

    Comparison Table: Olmesar vs. Other ARBs

    Feature

    Olmesartan (Olmesar)

    Losartan

    Valsartan

    Telmisartan

    Candesartan

    Efficacy (BP lowering)

    Greater reduction in both systolic and diastolic BP than losartan or valsartan; more potent arterial BP lowering shown in several studies 

    Effective, but generally less potent than olmesartan in direct comparisons 

    Effective but inferior to olmesartan for both SBP and DBP in head-to-head trials 

    Effective; slightly less strong than olmesartan in some studies 

    Effective; similar or slightly less potent than olmesartan 

    Dosing Convenience

    Once daily, long-acting, available in combinations with hydrochlorothiazide or amlodipine 

    Once daily, shorter half-life, generics widely available 

    Once or twice daily, depending on indication 

    Once daily, may have additional metabolic benefits 

    Once daily 

    Time to BP Control

    Shows faster onset and greater BP control within 2–8 weeks 

    Gradual onset; generally effective over weeks to months 

    Gradual onset; less effective at early timepoints 

    Comparable to others

    Comparable to others 

    Side Effect Profile

    Similar to other ARBs; low risk of adverse events; rare sprue-like enteropathy reported (diarrhea, weight loss) 

    Well tolerated, similar side effect risk 

    Similar profile to olmesartan, well tolerated 

    May be less likely to cause angioedema or cough 

    Comparable safety 

    Renal/Kidney Protection

    Demonstrated effective reduction of proteinuria vs. other ARBs 

    Effective, but not as strong as olmesartan

    Effective

    Effective 

    Effective 

    Expert Insights & Practical Tips

    • Maintain a balanced diet and healthy lifestyle for best results
    • Track your blood pressure regularly and keep a record to share with your healthcare provider
    • Stay hydrated and avoid excessive salt in your diet

    FAQs About OLSERTAIN 20MG TABLET

    Q: Can Olmesar 20mg Tablet be used to manage high blood pressure?

    A: Olmesar 20mg Tablet is used to manage high blood pressure. It contains olmesartan which helps to relax the blood vessels and then normalize the blood pressure.

    Q: Can Olmesar 20mg Tablet be given to children and adolescents?

    A: Olmesar 20mg Tablet is not recommended for use in children below 6 years of age. Your child’s doctor may adjust the dose based on the body weight of the child.

    Q: What happens if I stop taking Olmesar 20mg Tablet?

    A: Do not stop taking the medicine without talking to your doctor first. Stopping this medicine suddenly can cause your blood pressure to spike up and may increase the risk for heart conditions.

    Q: Can Olmesar 20mg Tablet be taken by patients with kidney problems?

    A: It should be taken with caution in patients with kidney problems. Your doctor may monitor your kidney function test before and during management with this medicine to manage the risk of kidney damage or any unusual effects due to the accumulation of medicine in the body.

    Q: What precautions do I need to follow while taking Olmesar 20mg Tablet?

    A: Patients taking Olmesar 20mg Tablet must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems.

    Q: How should I store Olmesar 20mg Tablet?

    A: Store in a cool, dry place away from sunlight. Keep out of reach of children.

    Q: What if I miss a dose of Olmesar 20mg Tablet?

    A: Take it as soon as you remember. If it is close to the next dose, skip the missed one, do not double the dose.

    Q: Can I take Olmesar 20mg Tablet during pregnancy?

    A: Olmesar 20mg Tablet is not recommended for use without consulting your doctor.

    Q: What are the common side effects of Olmesar 20mg Tablet?

    A: If you experience dizziness or persistent side effects like headache or stomach pain, seek medical advice.

    Q: What happens if I experience severe side effects or suspect overdose?

    A: Seek immediate medical attention if you notice symptoms like severe dizziness, fainting, difficulty breathing, swelling of the face or throat, or unusually slow or fast heartbeat.

    References

    1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page –535-538.

    2. Xiaoshen Zhang, Han Zhang, Yuxia Ma, Wenliang Che and Michael R. Hamblin. Management of Hypertension Using Olmesartan Alone or in Combination. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2017. [Accessed on 3rd November 2025]

    3. Kazuomi Kario, Ikuo Saito, Toshio Kushiro, Satoshi Teramukai, Mai Yaginuma, Yoshihiro Mori, Yasuyuki Okuda, Fumiaki Kobayashi and Kazuyuki Shimada. Persistent olmesartan-based blood pressure–lowering effects on morning hypertension in Asians: the HONEST study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. May 2016. [Accessed on 3rd November 2025] 

    4. Daiichi Sankyo. U.S. Food & Drug Administration. [Revised in May 2011] [Accessed on 3rd November 2025]

    Lab updated