Olmezest 20mg Tablet 10'S

Introduction About OLMEZEST 20MG TABLET

Olmezest 20mg Tablet is a prescription medication used by adults to help manage high blood pressure and support heart health. Its active ingredient, olmesartan, is an angiotensin II receptor blocker (ARB) that works by relaxing and widening blood vessels, making it easier for blood to flow and reducing the workload on the heart. This medication is particularly suitable for individuals who may not see enough improvement from lifestyle changes alone or who need additional protection for their kidneys and cardiovascular system.   

Olmezest 20mg Tablet is mainly prescribed for adults with hypertension (high blood pressure), and in some cases, it may be used for heart failure under medical supervision. The tablet is taken by mouth, usually once a day, with or without food, at a consistent time to help maintain stable blood pressure. It should be swallowed whole with water and not crushed or chewed. Your doctor will determine the right dose for you and may recommend regular check-ups to monitor your blood pressure and kidney function.

Before starting Olmezest 20mg Tablet, tell your doctor about all medications and supplements you are taking, especially potassium supplements or salt substitutes, as olmesartan can affect potassium levels. Avoid using nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen without consulting your doctor. This medication should not be used during pregnancy, as it may harm the unborn baby—if you become pregnant while taking Olmezest 20mg, stop using it and contact your doctor right away. Use while breastfeeding is generally not recommended unless specifically advised by your healthcare provider.

Common side effects may include dizziness, headache, nausea, indigestion, diarrhea, stomach pain, sore throat, and flu-like symptoms. Most of these are mild and temporary, but if they persist or become severe, seek medical attention. Always follow your doctor’s instructions and attend regular check-ups to ensure safe and effective use of Olmezest 20mg Tablet as part of your overall health plan.

Uses Of OLMEZEST 20MG TABLET

• Supports management of high blood pressure (hypertension)
• Helps maintain healthy blood flow by relaxing blood vessels
• Supports heart health by reducing strain on the cardiovascular system
• Assists in preserving kidney function (especially in patients with diabetes)

Benefits of OLMEZEST 20MG TABLET

Olmezest 20mg tablet for hypertension

Olmezest 20mg Tablet is an antihypertensive medication commonly used to help manage high blood pressure, also known as hypertension. The active ingredient, olmesartan, works by relaxing blood vessels, which allows blood to flow more easily and helps maintain healthy blood pressure levels. Regular use of Olmezest 20mg, as directed by your doctor, supports cardiovascular health and may reduce the risk of complications associated with high blood pressure. It is important to combine this medication with healthy lifestyle choices, such as a nutritious diet, regular exercise, and avoiding excessive salt and alcohol, for the best results.

Olmezest 20mg for heart failure

Olmezest 20mg Tablet may also be prescribed for individuals experiencing heart failure, under the supervision of a healthcare professional. In heart failure, the heart struggles to pump blood efficiently, often due to underlying conditions or chronic stress on the cardiovascular system. By blocking the effects of certain hormones that can strain the heart, Olmezest 20mg helps reduce the workload on the heart and supports improved function. Consistent use, along with regular medical check-ups, can help manage symptoms and promote better quality of life for those with heart failure.

Understanding the Role of Olmezest 20mg in Heart Health

Olmezest 20mg Tablet plays a significant role in supporting overall heart health by helping to control high blood pressure and reducing stress on the heart and blood vessels. By keeping blood pressure within a healthy range, this medication may help lower the risk of heart-related complications and protect other organs, such as the kidneys, from damage. Managing blood pressure is a key part of maintaining long-term cardiovascular well-being, and Olmezest 20mg is one of many tools that can be used as part of a comprehensive approach to heart health. Always consult your doctor to ensure this medication is right for your individual health needs.

How OLMEZEST 20MG TABLET Works

How does olmesartan lower blood pressure

Olmesartan lowers blood pressure by blocking the action of a hormone called angiotensin II. Normally, angiotensin II causes blood vessels to narrow, which can increase blood pressure. By blocking its effects, olmesartan helps keep blood vessels relaxed and open. This allows blood to flow more easily and helps maintain healthy blood pressure levels.

How Olmezest 20mg Tablet Relaxes Blood Vessels

Olmesartan lowers blood pressure by blocking the action of a hormone called angiotensin II. Normally, angiotensin II causes blood vessels to narrow, which can increase blood pressure. By blocking its effects, olmesartan helps keep blood vessels relaxed and open. This allows blood to flow more easily and helps maintain healthy blood pressure levels.

How Olmezest 20mg Supports Heart and Vascular Health

Olmezest 20mg Tablet supports heart and vascular health by helping to keep blood pressure within a healthy range and reducing unnecessary stress on the heart and arteries. By relaxing blood vessels, it promotes better circulation and may help protect against long-term complications related to high blood pressure. The active ingredient, olmesartan, also supports the health of blood vessel walls, contributing to overall cardiovascular well-being. Regular use, as prescribed by your doctor, can be an important part of a comprehensive approach to maintaining heart and vascular health.

How to use OLMEZEST 20MG TABLET

Recommended Dosage of Olmezest 20mg

• Standard adult dosage: 20 mg taken once daily
• Dose adjustment: May be increased to 40 mg daily under medical supervision if needed
• Doctor’s guidance: Always follow your doctor’s instructions for the correct dose
• Pediatric use: For children aged 6 and above, dosage is determined by body weight and medical condition

Can Olmezest 20mg Be Taken With or Without Food?

• Flexible timing: Can be taken with or without food, as advised by your doctor
• Consistency: Take at the same time each day for best results
• Swallowing: Swallow the tablet whole with water; do not crush, break, or chew

How much Olmezest 20mg should I take daily?

• Daily dose: Most adults take one 20 mg tablet per day
• Maximum dose: Up to 40 mg per day may be prescribed if needed
• Never exceed: Do not take more than your doctor recommends
• Missed dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for the next dose—never double the dose

Special Instructions for Elderly and Children

• Elderly patients: Use with caution, especially if kidney or liver function is reduced
• Dose adjustment: Doctor may start with a lower dose and monitor closely
• Children aged 6–16: Dose based on body weight; maximum of 20 mg daily for those under 35 kg
• Swallowing difficulty: For children who cannot swallow tablets, an oral suspension may be available—consult your doctor
• Doctor’s advice: Always consult your doctor for personalized dosage and administration instructions for children and elderly patients

What if I forgot to take OLMEZEST 20MG TABLET

If you forget to take your Olmezest 20mg tablet take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, simply skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could increase your risk of side effects. To help avoid missing doses in the future, consider setting a daily reminder or keeping your medication in a place where you will see it each day.

Overdose

Taking more than the prescribed amount of Olmezest 20mg tablet can lead to an overdose, which may cause symptoms such as severe dizziness, fainting, unusually slow or fast heartbeat, or difficulty breathing. If you suspect that you or someone else has taken too much of this medication, seek emergency medical attention or contact your doctor immediately. Do not wait for symptoms to appear before seeking help. To prevent accidental overdose, always store your medicine out of reach of children, keep track of your doses, and follow your doctor’s instructions carefully. Never share your medication with others.

Side Effects Of OLMEZEST 20MG TABLET

Common Side Effects of OLMEZEST 20MG TABLET:

• dizziness
• nausea, vomiting
• stomach pain, diarrhoea
• gastroenteritis (stomach flu)
• tiredness
• sore throat, cough
• runny or stuffy nose
• feeling of spinning (vertigo)
• muscular pain

When to Seek Medical Attention?

• allergic reactions (signs include swelling of the face, mouth and/or larynx (voice box), itching and rash)
• reduced blood pressure in susceptible individuals or because of allergic reaction which could cause severe light-headedness or fainting (more often in older people)

Warning & Precautions

Pregnancy

Contraindicated

OLMEZEST 20MG TABLET is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after the third month of pregnancy.  

Breastfeeding

Contraindicated

OLMEZEST 20MG TABLET is not recommended for use in breastfeeding women. Your doctor may choose another management especially if you want to breastfeed when your baby is a newborn or born prematurely.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or sleepy after taking OLMEZEST 20MG TABLET.

Kidney

Use with Caution

OLMEZEST 20MG TABLET should be taken with caution in patients with kidney problems.

Liver

Consult your doctor

OLMEZEST 20MG TABLET is not recommended for use in patients with jaundice (yellowing of the skin and eyes). It should be used with caution in patients having liver disease.

Allergy

Contraindicated

Do not take OLMEZEST 20MG TABLET if you are allergic to Olmesartan or any of the other ingredients of this medicine.

Heart Disease

Use with Caution

OLMEZEST 20MG TABLET should be taken with caution in patients with heart failure or problems with heart valves or heart muscles.  

Use In Pediatrics

Consult your doctor

OLMEZEST 20MG TABLET is not recommended for use in children below 6 years of age. Your child’s doctor may adjust the dose based on the body weight of the child. 

Use In Geriatrics

Use with Caution

OLMEZEST 20MG TABLET should be used with caution in elderly patients (aged 65 years and above)

Other Warnings for OLMEZEST 20MG TABLET

Before taking OLMEZEST 20MG TABLET, inform your doctor if you:

• severe vomiting, diarrhoea or if you are on a low salt diet
• take high doses of diuretics for the management
• problems with adrenal glands
• increased levels of potassium in the blood

Who should not take [GBNKEYWORD

OLMEZEST 20MG TABLET is not recommended for use if you:

• problems with the drainage of the bile from the gallbladder ((biliary obstruction Ex. gallstones)

Safety Advice

Olmezest 20mg: Safety Advice for Kidney and Liver Disease

If you have kidney or liver disease, it is important to use Olmezest 20mg Tablet with caution and only under medical supervision. For patients with kidney disease, especially severe cases, this medication is generally not recommended. If you have mild to moderate kidney problems, your doctor may prescribe Olmezest 20mg after careful evaluation and may adjust your dose as needed. Regular monitoring of kidney function, blood pressure, and potassium levels is essential while taking this medicine

For those with liver disease, Olmezest 20mg Tablet can usually be used safely in mild cases without dose adjustment. However, if you have severe liver disease, your doctor may need to adjust your dose or monitor your liver function more closely. Always inform your healthcare provider about any kidney or liver issues before starting this medication

Managing Potassium Levels While Taking Olmezest 20mg

Olmezest 20mg Tablet can increase potassium levels in your blood, which may lead to serious health issues if levels become too high. To manage this risk, avoid consuming potassium-rich foods such as bananas, potatoes, coconut water, fruit juices, and certain vegetables while on this medication. Also, do not take potassium supplements unless specifically advised by your doctor

Your doctor may recommend regular blood tests to check your potassium levels, especially if you have kidney disease or are taking other medications that affect potassium. If you experience symptoms such as muscle weakness, irregular heartbeat, or tingling sensations, contact your doctor immediately, as these may indicate high potassium levels

Diet and Lifestyle Advice

Here are the key diet and lifestyle recommendations for patients taking Olmezest 20mg Tablet:

Diet Advice

• Reduce Salt Intake: Limit the amount of salt (sodium) in your diet, as excessive salt can raise blood pressure and reduce the effectiveness of your medication
• Avoid Potassium-Rich Foods and Supplements: Unless specifically advised by your doctor, avoid consuming large amounts of potassium-rich foods (such as bananas, potatoes, coconut water) and potassium supplements, as Olmezest 20mg can increase blood potassium levels
• Eat a Balanced Diet: Consume a diet rich in proteins, whole grains, fibrous fruits, and vegetables. Limit intake of carbohydrates, salt, and sugar to support overall heart health
• Stay Hydrated: Drink plenty of fluids, especially if you experience side effects like diarrhea
• Avoid Spicy or Greasy Foods if Needed: If you have stomach upset or diarrhea, avoid spicy or greasy foods until your stomach settles

Lifestyle Advice

• Regular Exercise: Engage in regular physical activity such as walking, swimming, or other moderate exercise to help lower blood pressure and improve cardiovascular health
• Maintain a Healthy Weight: Keep your weight under control by following a healthy diet and staying active. Aim for a healthy body mass index (BMI)
• Quit Smoking: Smoking can increase blood pressure and damage your blood vessels. Quitting smoking is strongly recommended
• Limit Alcohol Intake: Reduce or avoid alcohol consumption, as it can raise blood pressure and interfere with your treatment
• Take Medication Consistently: Take Olmezest 20mg Tablet at the same time each day, with or without food, as advised by your doctor
• Regular Monitoring: Attend regular check-ups with your doctor to monitor your blood pressure, kidney function, and potassium levels

These steps will help you get the most benefit from your treatment and support your overall heart health. Always consult your doctor before making significant changes to your diet or lifestyle.

Olmezest 20mg vs. Olmezest AM: Key Differences

Olmezest 20mg vs. ACE Inhibitors for Heart Failure

Drug - Drug interaction

Olmezest 20mg Tablet (olmesartan) is a commonly prescribed medication for high blood pressure and heart health. However, it may interact with several other drugs, which can affect its effectiveness or increase the risk of side effects. Always inform your doctor about all medications, supplements, or herbal products you are taking. Below are important drug-drug interactions and how to manage them:

1. Aliskiren
   • Interaction: Using Olmezest 20mg together with aliskiren (another blood pressure medicine) is not recommended, especially for people with diabetes or kidney problems. This combination can increase the risk of kidney failure, high potassium levels, and very low blood pressure.
   • Management: Avoid using both medications together. Your doctor can suggest a safer alternative if needed.
2. ACE Inhibitors (such as lisinopril, ramipril)
   • Interaction: Combining Olmezest 20mg with ACE inhibitors can increase the risk of kidney damage, high potassium levels, and low blood pressure.
   • Management: Avoid using both types of medication together. If it is necessary, close monitoring of kidney function and potassium levels is essential.
3. NSAIDs (such as ibuprofen, aspirin)
   • Interaction: Nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the blood pressure-lowering effect of Olmezest 20mg and increase the risk of kidney damage.
   • Management: Use NSAIDs only when necessary and under your doctor’s supervision. Regular monitoring of kidney function and blood pressure is important.
4. Potassium-Sparing Diuretics (such as spironolactone) or Potassium Supplements
   • Interaction: Taking Olmezest 20mg with potassium-sparing diuretics or potassium supplements can cause dangerously high potassium levels, leading to heart rhythm problems.
   • Management: Avoid potassium supplements and foods high in potassium unless advised by your doctor. Regular blood tests to check potassium levels are recommended.
5. Lithium
   • Interaction: Olmezest 20mg may increase the level of lithium in your blood, raising the risk of lithium toxicity (such as tremors, confusion).
   • Management: If you need to take both medications, your doctor will closely monitor your lithium levels and may adjust your dose as needed.
6. Colesevelam (cholesterol medication)
   • Interaction: Colesevelam can reduce the absorption of Olmezest 20mg, making it less effective.
   • Management: Take Olmezest 20mg at least 4 hours before taking colesevelam.
7. Other Antihypertensives (such as diuretics, beta-blockers)
   • Interaction: Using Olmezest 20mg with other blood pressure medications can cause your blood pressure to drop too low, leading to dizziness or fainting.
   • Management: Your doctor will monitor your blood pressure regularly and may adjust your doses as needed.

Drug - Food interaction

Olmezest 20mg Tablet is generally considered safe to take with most foods, but there are a few important considerations regarding food and beverage intake that patients should be aware of. While specific food interactions are rare, certain dietary choices may affect your response to the medication or increase the risk of side effects. Always consult your doctor about your diet while taking this medicine.

1. Potassium-Rich Foods

• Interaction: Olmezest 20mg Tablet can increase potassium levels in your blood. Consuming large amounts of potassium-rich foods (such as bananas, potatoes, coconut water, fruit juices, and certain vegetables) may further raise your potassium levels, potentially leading to hyperkalemia (high potassium), which can cause serious heart rhythm problems.
• Management: Avoid excessive intake of potassium-rich foods and do not take potassium supplements unless specifically recommended by your doctor. Regular monitoring of blood potassium levels is advised

        2. Grapefruit and Grapefruit Juice

• Interaction: While grapefruit is not known to interact with olmesartan itself, it is important to note that some combination products (such as Olmezest AM, which contains both olmesartan and amlodipine) can interact with grapefruit, potentially increasing the risk of side effects from amlodipine.
• Management: If you are taking a combination product that includes amlodipine, avoid grapefruit and grapefruit juice. For olmesartan alone, there is no known interaction with grapefruit

         3. Alcohol

• Interaction: Drinking alcohol while taking Olmezest 20mg Tablet may increase the risk of dizziness, lightheadedness, or fainting due to additive effects on lowering blood pressure. However, there is no direct evidence that alcohol affects olmesartan’s effectiveness.
• Management: Limit alcohol intake and avoid excessive drinking. Be cautious when rising from a sitting or lying position, as dizziness may occur

Synopsis

More Information

FAQs About OLMEZEST 20MG TABLET

References

1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page –535-538.

2. Xiaoshen Zhang, Han Zhang, Yuxia Ma, Wenliang Che and Michael R. Hamblin. Management of Hypertension Using Olmesartan Alone or in Combination. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2017. [Accessed on 27th June 2025] 

3. Kazuomi Kario, Ikuo Saito, Toshio Kushiro, Satoshi Teramukai, Mai Yaginuma, Yoshihiro Mori, Yasuyuki Okuda, Fumiaki Kobayashi and Kazuyuki Shimada. Persistent olmesartan-based blood pressure–lowering effects on morning hypertension in Asians: the HONEST study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. May 2016. [Accessed on 27th June 2025] 

4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 27th June 2025] 

5. Daiichi Sankyo. U.S. Food & Drug Administration. [Revised in May 2011] [Accessed on 27th June 2025] 

Useful Diagnostic Tests

• ECG at Home
• ECG + BP Check at Home
• Full Body Checkup with ECG & BP at Home
• Comprehensive Cardiac Risk Screening with 12 Lead ECG and BP\
• Cardiac Risk Profile
• Kidney package Basic

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 27 Jun 2025 | 03:25 PM(IST)