OLMETIME CT 40mg Tablet 10's

Introduction About OLMETIME CT 40MG TABLET

OLMETIME CT 40MG TABLET is a combination of Chlorthalidone and Olmesartan which belongs to the group of medicines called Thiazide diuretics and Angiotensin-II receptor antagonists respectively. OLMETIME CT 40MG TABLET is indicated for the management of essential hypertension.

Essential hypertension (also known as primary hypertension) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result, it may lead to severe damage to the walls of blood vessels supplying various important organs. It occurs without any known secondary cause and if it remains unmanageed it can lead to severe problems such as heart attack, heart or kidney failure, stroke or even blindness.

Along management with OLMETIME CT 40MG TABLET follow lifestyle modifications (such as losing weight, quitting smoking or alcohol intake) as advised by your physician along with a healthy balanced diet and regular physical activity (such as walking or swimming).

During the course of the management with OLMETIME CT 40MG TABLET, your doctor might regularly check your blood pressure, kidney function and electrolyte balance to avoid the risk of side effects. Avoid eating grapefruit or consuming grapefruit juice while taking OLMETIME CT 40MG TABLET as it could potentiate the blood pressure-lowering effect of this medicine.

Before taking OLMETIME CT 40MG TABLET, inform your doctor if you have diabetes, liver, kidney or heart disease as a precaution. OLMETIME CT 40MG TABLET is strictly not recommended for use in pregnant or breastfeeding women as it could cause serious harm to the baby.

OLMETIME CT 40MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to a lack of safety data. It should be used with extreme caution in elderly patients (aged 65 years or above).

The most common side effects of taking OLMETIME CT 40MG TABLET are headache, dizziness, tiredness, nausea, stomach pain, lack of appetite and indigestion. Consult your doctor if any of the side effects worsen.

Uses Of OLMETIME CT 40MG TABLET

• Manage essential hypertension

How OLMETIME CT 40MG TABLET Works

OLMETIME CT 40MG TABLET effectively reduces elevated blood pressure where olmesartan acts by blocking the actions of Angiotensin – II (a substance that causes narrowing of blood vessels and increases in blood pressure) at the angiotensin type-I receptors of the vascular smooth muscle and chlorthalidone acts by increasing the urinary excretion of sodium and water by inhibiting sodium-chloride reabsorption in the kidneys, thus leading to a marked decrease in blood pressure. 

How to use OLMETIME CT 40MG TABLET

Take OLMETIME CT 40MG TABLET as advised by your physician. Swallow OLMETIME CT 40MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Overdose

If you or anyone else accidentally take too much of OLMETIME CT 40MG TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of OLMETIME CT 40MG TABLET might include dizziness, excess sleepiness, nausea, hypovolemia, low blood pressure and electrolyte disturbances associated with cardiac arrhythmias and muscle spasms.

Side Effects Of OLMETIME CT 40MG TABLET

Common side effects of OLMETIME CT 40MG TABLET:

• headache and dizziness
• nausea, indigestion, diarrhoea, stomach pain
• tiredness
• sore throat, runny nose, flu-like symptoms, cough
• chest pain, back pain, joint pain
• urinary tract infection
• swelling of the feet, ankles, hands or arms
• blood in urine
• skin rash
• orthostatic hypertension (feeling dizzy while standing up)
• loss of appetite
• impotence in men

Stop taking OLMETIME CT 40MG TABLET and contact your doctor immediately if you experience any of the following side effects:

• severe allergic reactions (such as skin rash, itching, swelling of the face, mouth and/or larynx)
• severe hypotension (low blood pressure) with light-headedness or fainting

How To Manage Side Effects

Constipation

Eat fibre-rich foods such as fresh fruits, vegetables, cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom does not improve on its own.fs

Diarrhea

Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own to manage diarrhoea. Consult your doctor if the symptom does not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Headache

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.

Nausea And Vomiting

Try to take OLMETIME CT 40MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if the symptom does not improve.

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom did not improve on its own.

Warning & Precautions

Pregnancy

Contraindicated

OLMETIME CT 40MG TABLET is not recommended for use in pregnant women because it can cause serious harm to the developing fetus. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Breastfeeding

Contraindicated

OLMETIME CT 40MG TABLET is not recommended for use in breastfeeding women because it passes through the breast milk and could cause serious harm to the baby. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines if you experience dizziness, sleepiness or tiredness. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Alcohol

Contraindicated

Avoid consumption of alcohol while taking OLMETIME CT 40MG TABLET, as it could aggravate your existing disease condition. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Kidney

Consult your doctor

OLMETIME CT 40MG TABLET is not recommended for use in patients with severe kidney problems, kidney failure, lack of urine, and kidney stones and should be used with caution in patients with kidney problems. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Liver

Consult your doctor

OLMETIME CT 40MG TABLET is not recommended for use in patients with severe liver disease, jaundice (yellowing of skin and eyes) or biliary obstruction (a problem in bile drainage) and should be used with caution in patients with liver disease. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Allergy

Contraindicated

Do not take OLMETIME CT 40MG TABLET if you are allergic to Chlorthalidone, Olmesartan or any sulphonamide derivatives (Ex. sulfadiazine, sulfamethazine).

Heart Disease

Consult your doctor

OLMETIME CT 40MG TABLET is not recommended for use in patients with heart failure or attack, cardiogenic shock, narrowing of the aortic heart valve and severe low blood pressure. It should be used with caution in patients with coronary or cerebral arteriosclerosis and obstructive hypertrophic cardiomyopathy (heart muscle becomes abnormally thick). Consult your doctor before taking OLMETIME CT 40MG TABLET.

Use In Pediatrics

Contraindicated

OLMETIME CT 40MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to a lack of safety data. Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

OLMETIME CT 40MG TABLET should be used with extreme caution in elderly patients (aged 65 years or above). Proper dose adjustments and careful monitoring of blood pressure, kidney function and electrolyte balance are required in such patients. Consult your doctor before taking OLMETIME CT 40MG TABLET.

Other Warnings for OLMETIME CT 40MG TABLET

Before taking OLMETIME CT 40MG TABLET, inform your physician if you:

• have high blood cholesterol levels
• are on a low-sodium diet
• have severe vomiting or diarrhea
• have hyperkalemia (increased blood potassium levels)
• have metabolic acidosis (increase in plasma acidity)
• have a condition that involves cellular breakdown or damage (Ex. acute limb ischemia (decrease blood flow to lower limb), rhabdomyolysis (severe muscle injury), extended trauma)
• have hyperparathyroidism (overactive parathyroid gland)
• have recently had an anesthetic

Who should not take OLMETIME CT 40MG TABLET

OLMETIME CT 40MG TABLET is not recommended for use if you have:

• severe fluid-electrolyte imbalance (such as low levels of potassium, sodium or calcium in the blood)
• a history of gout
• unmanageed addison's disease (an endocrine disorder of adrenal glands)
• primary aldosteronism (a disorder due to increased aldosterone production)
• diabetes or diabetes-related kidney problems (Ex. diabetic nephropathy)

Drug - Drug interaction

Before taking OLMETIME CT 40MG TABLET inform to your doctor, if you are taking any of these medicines:

• other medicines used to reduce high blood pressure and other heart problems such as angiotensin-converting enzyme (ACE) inhibitors (Ex. captopril, enalapril), angiotensin receptor blockers (Ex. losartan, valsartan), calcium channel blockers (Ex. nifedipine, diltiazem, verapamil), beta-blockers (Ex. atenolol, propranolol), vasodilators (Ex. nitroglycerin, bosentan), digoxin, methyldopa, guanethidine or aliskiren
• hypericum perforatum (herbal medicine), lithium (used to manage depression or other mental illness)
• non-steroidal anti-inflammatory drugs (used to manage pain or inflammation) Ex. indomethacin
• simvastatin, colesevelam and cholestyramine (used to control high blood cholesterol levels)
• antacids (used to neutralize stomach acid) Ex. aluminium hydroxide, magnesium hydroxide
• ketoconazole, itraconazole or amphotericin (used to manage fungal infections)
• protease inhibitors (used to manage HIV infection) Ex. ritonavir, indinavir, nelfinavir
• certain antibiotics (used to manage bacterial infections) Ex. rifampicin, erythromycin, clarithromycin
• dantrolene (used to manage muscle spasticity)
• immunosuppressant (used to suppress immune function and manage graft rejection) Ex. tacrolimus, sirolimus, temsirolimus, everolimus or cyclosporine
• adrenocorticotropic hormone (used to manage various endocrine disorders)
• corticosteroids (used to manage allergic or inflammatory diseases and immune reactions) such as prednisolone or betamethasone
• anticholinergics (used to reduce stomach spasms or cramps) such as atropine, biperiden or hyoscine butylbromide
• cyclophosphamide or methotrexate (used to manage certain forms of cancer)
• salbutamol or formoterol (used to manage asthma)
• amantadine (a medicine used to manage viral infections or Parkinson’s disease)
• allopurinol (a medicine used to manage gout)
• carbenoxolone (a medicine used to manage stomach ulcers)
• calcium salts or vitamin D (used as a supplement)
• medicines used to manage diabetes (Ex. insulin, chlorpropamide or glibenclamide)
• diazoxide (used to manage low blood glucose levels)
• medicines that can alter blood potassium levels such as potassium-sparing diuretics (Ex. spironolactone, acetazolamide), salt substitutes containing potassium (Ex. losartan potassium)
• heparin (used to manage or manage blood clots)

Drug - Food interaction

OLMETIME CT 40MG TABLET can be taken with or without food. Avoid consumption of grapefruit or grapefruit juice while taking OLMETIME CT 40MG TABLET as it may cause severe decrease in blood pressure.

Synopsis

More Information

FAQs About OLMETIME CT 40MG TABLET

References

1. KD. Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 559 & 561-562.

2. Thomas Michel and Brian B. Hoffman. Treatment of Myocardial ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 767-770 & 778.

3. Gerald G. Briggs and Roger K. Freeman. C. and O. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 760 & 2852.

4. Dr. G. Chitti Pantulu, Dr. Avinash Shende, Dr. Prathmesh Mule and Dr. A. A. Faruqui. Evaluation of efficacy and safety of oral olmesartan and chlorthalidone fixed dose combination in the management of hypertension in Indian Patients. International journal of current research. [Accessed on 22nd June 2026]

5. Elena Filipova, Stela Dineva , Katya Uzunova, Velichka Pavlova, Krassimir Kalinov and Toni Vekov. Combining angiotensin receptor blockers with chlorthalidone or hydrochlorothiazide – which is the better alternative? A meta-analysis. Systematic reviews. BMC. 2020. [Accessed on 22nd June 2026]

Useful Diagnostic Tests

• Kidney Function Test (KFT)

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 22 Jun 2026 | 03:25 PM(IST)