OLMAT 40 AMH Tablet 15's

Introduction About OLMAT 40 AMH TABLET

OLMAT 40 AMH TABLET is a combination of Amlodipine, Hydrochlorothiazide and Olmesartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure) when management with single agents is not effective.

Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney, or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

During management with OLMAT 40 AMH TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects. Avoid eating grapefruit or drinking grapefruit juice while taking OLMAT 40 AMH TABLET as it may severely decrease your blood pressure.

Before taking OLMAT 40 AMH TABLET inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.

OLMAT 40 AMH TABLET is also not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking OLMAT 40 AMH TABLET and inform your doctor immediately if you become pregnant while undergoing therapy with OLMAT 40 AMH TABLET.

The most common side effects of taking OLMAT 40 AMH TABLET are low blood pressure, dizziness, tiredness, headache, sleepiness, muscle cramps and swollen ankles. Contact your doctor if any of these side effect worsens.

Uses Of OLMAT 40 AMH TABLET

• Manage Hypertension (high blood pressure)

How OLMAT 40 AMH TABLET Works

OLMAT 40 AMH TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

How to use OLMAT 40 AMH TABLET

Take OLMAT 40 AMH TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take OLMAT 40 AMH TABLET at the same time each day. OLMAT 40 AMH TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Continue to take OLMAT 40 AMH TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

Overdose

If you or anyone else accidentally took more OLMAT 40 AMH TABLET, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, and dizziness.

Side Effects Of OLMAT 40 AMH TABLET

Common side effects of OLMAT 40 AMH TABLET:

• low blood pressure
• swelling of ankles and legs (edema)
• headache, dizziness
• nausea, vomiting, stomach pain, constipation, diarrhea, indigestion
• sleepiness or lack of sleep
• abnormal heartbeat (fast or slow)
• muscle cramps
• chest pain, back pain, joint pain
• cough, sore throat, sinus infections, nasal congestion
• high blood potassium levels
• low blood sugar levels
• urinary tract infections
• increased blood cholesterol levels
• increased uric acid levels in blood

Stop taking OLMAT 40 AMH TABLET and contact your doctor immediately if you experience any of the following side effects such as:

• signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
• severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
• chest pain, shortness of breath
• inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
• skin rashes or lesions
• eye pain or decrease in vision
• orthostatic hypotension (dizziness while standing up from sitting or lying position)
• severe chronic diarrhea with weight loss
• signs of kidney problems (such as edema, tiredness, bloody urine)

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take OLMAT 40 AMH TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Warning & Precautions

Pregnancy

Contraindicated

OLMAT 40 AMH TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking OLMAT 40 AMH TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with OLMAT 40 AMH TABLET, stop taking it and consult your doctor immediately. 

Breastfeeding

Contraindicated

OLMAT 40 AMH TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking OLMAT 40 AMH TABLET.

Alcohol

Contraindicated

Avoid consumption of alcohol while taking OLMAT 40 AMH TABLET as it might make you feel dizzier and drowsier.

Kidney

Consult your doctor

OLMAT 40 AMH TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it.

Liver

Use with Caution

OLMAT 40 AMH TABLET is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take OLMAT 40 AMH TABLET if you are allergic to Amlodipine, Olmesartan or Hydrochlorothiazide.

Heart Disease

Consult your doctor

OLMAT 40 AMH TABLET is not recommended for use in patients with serious heart problem (such as heart failure or heart attack). It should be used with caution in patients with heart problems (such as irregular heart rhythm and problems with heart muscle or valves). Therefore, consult your doctor before taking it.

Use In Pediatrics

Contraindicated

OLMAT 40 AMH TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice.

Use In Geriatrics

Use with Caution

OLMAT 40 AMH TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.

Other Warnings for OLMAT 40 AMH TABLET

Before taking OLMAT 40 AMH TABLET, inform your doctor if you:

• have primary hyperaldosteronism (problems in adrenal gland)
• have low blood pressure
• are severely dehydrated (due to diarrhea, vomiting or excess sweating)
• are on a low-salt diet
• have diabetes
• have hyperkalemia (high blood potassium levels)
• have unstable angina (a type of chest pain)
• have narrowing of arteries
• have gout (painful joints)
• have had skin cancer

Who should not take OLMAT 40 AMH TABLET

OLMAT 40 AMH TABLET is not recommended for use if you:

• have cardiogenic shock (heart cannot pump blood suddenly)
• have diabetes related kidney problems

Drug - Drug interaction

• medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim)
• medicine used to manage HIV infection (Ex. indinavir, ritonavir, saquinavir)
• medicines used to manage fungal infections (Ex. itraconazole, ketoconazole and fluconazole)
• medicines used for heart problems (such as verapamil, diltiazem)
• dantrolene (a medicine used to manage muscle spasms)
• medicines to suppress immune system (Ex. cyclosporin, tacrolimus, sirolimus, temsirolimus and everolimus)
• simvastatin, cholestyramine and colestipol (medicines to lower the cholesterol)
• potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
• antidepressants such as lithium, citalopram, fluoxetine, paroxetine, nefazodone, St. John’s wort (herbal medicine used to manage depression)
• other medicines used to manage elevated blood pressure (such as aliskiren, bosentan, methyldopa, guanethidine, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan)
• other diuretics (used to reduce edema) Ex. furosemide, bumetanide
• adrenaline or nor-adrenaline (used for low blood pressure, shock, cardiac failure, asthma or allergies)
• medicines used to manage gout (such as probenecid, sulfinpyrazone and allopurinol)
• laxatives (used to manage constipation) Ex. lactulose
• glycyrrhizin (a medicine used to reduce bronchitis)
• anti-diabetic medicines and insulin (used to lower the blood glucose level) Ex. vildagliptin, metformin
• corticosteroids (used to manage inflammation) Ex. prednisolone
• iodinated contrast agents (used during X-ray procedures)
• atropine (a medicine used to improve heart rate)
• biperiden (a medicine used to manage parkinsonism)
• antipsychotics (used to manage serious mental illnesses) Ex. clozapine, risperidone
• medicines used to relieve pain (Ex. morphine, aspirin, diclofenac, diflunisal, celecoxib, valdecoxib)

Drug - Food interaction

Do not eat grapefruit or drink grapefruit juice while taking OLMAT 40 AMH TABLET as it may increase the risk of side effects

Synopsis

More Information

FAQs About OLMAT 40 AMH TABLET

References

1. KD. Tripathi. Antihypertensive Drugs. Drugs Affecting Renin-Angiotensin System and Plasma Kinins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 559, 505-508, 561 & 562.

2. Lars C. Rump, MD, PhD, Bettina Ammentorp, Petra Laeis, and Jürgen Scholze, MD, PhD. Adding Hydrochlorothiazide to Olmesartan/Amlodipine Increases Efficacy in Patients With Inadequate Blood Pressure Control on Dual-Combination Therapy. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2015. [Accessed on 29th May 2026] 

3. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2018] [Accessed on 29th May 2026] 

4. Mylan Pharmaceuticals Inc. U.S. Food and Drug Administration. HYDROCHLOROTHIAZIDE TABLETS, USP 12.5 mg, 25 mg and 50 mg. [Revised in May 2011] [Accessed on 29th May 2026] 

5. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 29th May 2026] 

6. Central Drugs Standard Control Organization. Amlodipine Besilate IP eq.to Amlodipine 10mg/5mg/5mg/5mg/2.5mg + Olmesartan Medoxomil 40mg/40mg/20mg/5mg/5mg + Hydrochlorothiazide IP 25mg/12.5mg/12.5mg/12.5mg/12.5mg Tablet. November 2011. [Accessed on 29th May 2026] 

Useful Diagnostic Tests

• Kidney Function Test (KFT)

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 30 May 2026 | 09:58 AM(IST)