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Introduction About OBRIN EYE/EAR DROPS
OBRIN EYE/EAR DROPS contains Tobramycin which belongs to the group of antibiotics known as Antibiotics. It is used to manage bacterial infections of the external part of the eye, such as conjunctivitis and ear canal infections.
Bacterial conjunctivitis is the infection of the transparent membrane (conjunctiva) that lines the eyelid and covers the white part of your eyeball. Symptoms of bacterial conjunctivitis include pain, discomfort, redness, itching, irritation, and watering of the eyes. Ear canal infection is the bacterial infection of external ear, which is characterised by ear pain, redness and swelling around the ear canal, discharge of fluid or pus from ear.
Do not wear contact lens if you have any ocular infection while using OBRIN EYE/EAR DROPS. Remove the contact lenses before using OBRIN EYE/EAR DROPS and can put them back after 15 minutes of use.
OBRIN EYE/EAR DROPS should be used with caution in patients who have ever had neuromuscular disorders, such as myasthenia gravis or Parkinson’s disease.
OBRIN EYE/EAR DROPS should be used with caution in pregnant and breastfeeding woman. Consult your doctor before using the medicine.
The safety and effectiveness of OBRIN EYE/EAR DROPS in children under the age of 12 months has not been established. Consult your doctor before using the medicine.
The common side effects of using this medicine are swollen/itchiness in eyelids, eye irritation, redness of eyes, watery eyes. Consult your doctor if the symptom worsens or does not improve.
Uses Of OBRIN EYE/EAR DROPS
It is used to manage:
- eye infections such as conjunctivitis, blepharitis, pediatric ocular infections, vision affecting eye infections, post eye operation
- ear canal infections
How OBRIN EYE/EAR DROPS Works
OBRIN EYE/EAR DROPS effectively works against the disease-causing bacteria by binding irreversibly to one of two amino glycoside binding sites on the 30 S ribosomal subunit of bacteria thereby terminating the bacterial growth.
How to use OBRIN EYE/EAR DROPS
Always use OBRIN EYE/EAR DROPS exactly as directed by your physician. It is for external use only. Instill the medicine into the affected eye or ear 1 to 2 times a day or as directed by the physician. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.
Side Effects Of OBRIN EYE/EAR DROPS
Common
- eye/ear irritation
- inflammation of the cornea (clear front portion of your eye)
- swollen/itchiness in eyelids
- redness of eyes
- watery eyes (increased tearing)
Rare
Stop using OBRIN EYE/EAR DROPS and contact your doctor immediately if you experience any of the following side effects:
- skin rashes
- swelling of the face, hands, or legs
- wheezing, difficulty in breathing, shortness of breath
- severe and sudden appearance of pinkish, itchy swellings on the skin, also called hives or nettle rash
Warning & Precautions

Pregnancy
OBRIN EYE/EAR DROPS should be used with caution in pregnant women. Consult your doctor before using.

Breastfeeding
OBRIN EYE/EAR DROPS should be used with caution in breastfeeding woman. Consult your doctor before using.

Driving and Using Machines
Do not drive or handle any machines while using this medicine, since it may cause blurred vision or other visual disturbances.

Allergy
Do not use OBRIN EYE/EAR DROPS you are allergic to Tobramycin or to any other ingredients of this medicine.
Others
Before using OBRIN EYE/EAR DROPS, inform your doctor if you:
- have or ever had neuromuscular disorders, such as myasthenia gravis or Parkinson’s disease
Use in pediatrics:
The safety and effectiveness of OBRIN EYE/EAR DROPS in children under the age of 12 months has not been established. Consult your doctor for advice.
Use in geriatrics:
There is no information regarding the use of OBRIN EYE/EAR DROPS in elderly patients. Your doctor will prescribe you the correct dose and duration of OBRIN EYE/EAR DROPS depending upon your age, body weight and severity of infection.
Interactions
A. Drug-Drug interactions:
- penicillin’s, cephalosporins (medicines used to manage infections of the eye, ear, or the skin)
- gentamicin, amikacin (medicines used to manage bacterial infections)
Overdosage:
If you or anyone else accidentally use too much of OBRIN EYE/EAR DROPS, consult your doctor immediately or visit the nearby hospital. If accidentally occurs, wash your eyes or ear and rinse it all out with warm water.
Synopsis
Drug | : | Tobramycin |
Pharmacological Category | : | Antibiotics |
Therapeutic Indication | : | Eye and Ear infections |
Dosage Forms | : | Respule (Inhalation solution), Eye drops, Eye/Ear drops, Eye ointment, Injection |
More Information
- Keep out of reach of children
- Store below 25°C
FAQs About OBRIN EYE/EAR DROPS
What is OBRIN EYE/EAR DROPS and why it is given?
It is used to manage bacterial infections of the external part of the eye, such as conjunctivitis and ear canal infections.
How does OBRIN EYE/EAR DROPS works?
OBRIN EYE/EAR DROPS effectively works against the disease-causing bacteria by binding irreversibly to one of two amino glycoside binding sites on the 30 S ribosomal subunit of bacteria thereby terminating the bacterial growth.
How to use OBRIN EYE/EAR DROPS?
Always use OBRIN EYE/EAR DROPS exactly as directed by your physician. It is for external use only. Instill the medicine into the affected eye or ear 1 to 2 times a day or as directed by the physician. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.
Does OBRIN EYE/EAR DROPS cause eye irritation?
Yes, it may cause itching and burning sensation of eyes in some patients. Close your eyes and relax for some time. Place an ice pack over the eyes for few minutes. Avoid watching mobile phone, system, laptop, or any other light sources which might irritate your eyes. If the symptom persists or worsens, contact your doctor.
Can OBRIN EYE/EAR DROPS be used in children?
The safety and effectiveness of OBRIN EYE/EAR DROPS in children under the age of 12 months has not been established. Consult your doctor for advice before using OBRIN EYE/EAR DROPS.
References
1. KD Tripathi MD. Aminoglycosides antibiotics. Essentials of Medical Pharmacology 8th edition. Page – 793.
2 Mark Abelson, Eugene Protzko, Aron Shapiro, Ana Garces-Soldana, and Lyle Bowman azithromycin in. A randomized trial assessing the clinical efficacy and microbial eradication of 1% azithromycin ophthalmic solution vs tobramycin in adult and pediatric subjects with bacterial conjunctivitis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2007. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704516/
3. Qin Xiang, MM, Dan Hu, and Xu Gao, Tobramycin/dexamethasone eye drops as a better choice for lacrimal duct probing in persistent congenital nasolacrimal duct obstruction. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. February 2019. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380727/
4. Novartis New Zealand Limited. [Revised in November 2021] [Accessed 19th July 2022] https://www.medsafe.govt.nz/Consumers/cmi/t/tobrexdrops.pdf
5. ALCON LABORATORIES. U.S. Food & Drug Administration [Revised in June 2012] [Accessed 19th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050541s024lbl.pdf
6. Pharmatak ophthalmic. [Accessed 19th July 2022] https://www.pharmtakindia.com/product/tobram-eye-ear-drops/