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Introduction About NYXOCAINE 2% JELLY GEL
NYXOCAINE 2% JELLY is a local anaesthetic medicine used as an anaesthetic lubricant prior to catheterization, tracheal intubation and diagnostic procedures (such as proctoscopy, rectoscopy, cystoscopy, gastroscopy, bronchoscopy, esophagoscopy etc.). It contains lignocaine (also known as lidocaine) which is a local anaesthetic that numbs the body sites where it has been applied. It can also provide temporary relief of pain and discomfort associated with cystitis and urethritis.
NYXOCAINE 2% JELLY should be used under medical supervision. It will be administered to you only by a doctor or a qualified healthcare professional. Alternatively, it can also be self-administered if instructed by the doctor.
Before using NYXOCAINE 2% JELLY inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any infections or injuries at the site of application or a history of epilepsy as a precaution. Inform your doctor before NYXOCAINE 2% JELLY is administered to you, if you are pregnant or breastfeeding as a precaution.
It is generally safe and well tolerated without any major side effects. However, few individuals may experience light headedness, dizziness, drowsiness, blurred vision, sense of vomiting, slow heart rate and low blood pressure. Consult your doctor if they trouble you.
Uses Of NYXOCAINE 2% JELLY GEL
- Temporarily numbs the areas where it has been applied
- Acts as an anaesthetic lubricant prior to invasive and diagnostic procedures
- Provides temporary relief of pain and discomfort associated with cystitis and urethritis.
How NYXOCAINE 2% JELLY GEL Works
NYXOCAINE 2% JELLY is a local anaesthetic agent. It reduces pain sensation and causes numbness of body parts by blocking the flow of certain ions (sodium ions) through the nerves that causes pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., face, hands, legs, abdomen, pelvis, genitals or where the medicine has been applied) to the brain which ultimately leads to loss of sensation.
How to use NYXOCAINE 2% JELLY GEL
NYXOCAINE 2% JELLY is a local anaesthetic agent. It reduces pain sensation and causes numbness of body parts by blocking the flow of certain ions (sodium ions) through the nerves that causes pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., face, hands, legs, abdomen, pelvis, genitals or where the medicine has been applied) to the brain which ultimately leads to loss of sensation.
However, it can also be self-administered by the patients if instructed by the doctor. Take a small quantity of NYXOCAINE 2% JELLY and apply on the required areas. Avoid contact of NYXOCAINE 2% JELLY with your eyes.
Side Effects Of NYXOCAINE 2% JELLY GEL
Common
- light headedness, dizziness, drowsiness
- nervousness, tinnitus, blurred or double vision
- vomiting
- sensations of heat, cold or numbness
- twitching, tremors
- slow heart rate
- low blood pressure
Consult your doctor immediately if you experience any of the following after using NYXOCAINE 2% JELLY:
- signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, or tongue causing difficulty in breathing or swallowing)
- dizziness or drowsiness, confusion, shortness of breath, ringing in the ears, blurred vision, slow heartbeat, feeling faint, nervousness, unusual sweating, trembling or seizures
- signs of methemoglobinemia (such as pale, grey, or bluish discoloration of the skin, headache, abnormal or irregular heartbeat, dizziness, and tiredness etc.)
How To Manage Side Effects
Dizziness Or Drowsiness
Ensure you stay hydrated, as dehydration is a common trigger. Eating regular, balanced meals helps maintain stable blood sugar levels. When feeling dizzy, sit or lie down immediately to prevent falls. Move slowly when changing positions to avoid sudden drops in blood pressure. Avoiding alcohol, caffeine, and smoking can also reduce dizziness. Additionally, manage stress through relaxation techniques like deep breathing or meditation. If dizziness persists or is severe, consult a healthcare professional to rule out serious conditions and receive appropriate management.
Warning & Precautions
Pregnancy
Consult your doctorThere are no adequate and well-controlled studies regarding the use of lignocaine 2% jelly in pregnant women. Therefore, before using NYXOCAINE 2% JELLY, inform your doctor if you are pregnant or think you may be pregnant as a precaution.
Breastfeeding
Use with CautionStudies have shown that lignocaine can be excreted in the breast milk. However, at therapeutic doses, the quantities of lignocaine in breast milk are small and generally are not expected to be a risk for the nursing infant. Therefore, NYXOCAINE 2% JELLY should be used with caution among breastfeeding mothers.
Driving and Using Machines
Use with CautionNYXOCAINE 2% JELLY has no effect on the ability to drive and use machines. However, do not drive or handle heavy machineries if your abilities is affected by this medicine.
Kidney
Use with CautionNYXOCAINE 2% JELLY should be used with caution in patients with kidney diseases. Therefore, consult your doctor before application.
Liver
Use with CautionNYXOCAINE 2% JELLY should be used with caution in patients with liver diseases. Therefore, consult your doctor before application.
Allergy
ContraindicatedNYXOCAINE 2% JELLY is contraindicated for use in patients who are allergic to lignocaine or similar local anaesthetics.
Heart Disease
Use with CautionNYXOCAINE 2% JELLY should be used with caution in patients with heart diseases (such as heart block, or an abnormal or very slow heartbeat). Therefore, consult your doctor before application.
Use In Pediatrics
Consult your doctorNYXOCAINE 2% JELLY can be used in children and adolescents (aged 2-18 years) if recommended by your physician. However, it should be used with extreme caution in infants aged 2 years or older and not suitable for use in infants aged below 1 year.
Use In Geriatrics
Use with CautionNYXOCAINE 2% JELLY should be used with caution in elderly patients. Therefore, consult your doctor for advice.
Others
NYXOCAINE 2% JELLY is not recommended for use in patients with:
- congenital or idiopathic methemoglobinemia
Before using NYXOCAINE 2% JELLY, inform your physician if you:
- have any open wounds, injuries, or infections at the site of application
- have porphyria (a rare inherited blood disorder)
- have epilepsy (fits)
Interactions
Drug-Drug Interactions:
- Anti-arrhythmic agents (such as mexiletine, amiodarone)
- Cimetidine (a medicine for stomach ulcers)
- Beta-blockers such as atenolol, propranolol, bisoprolol
- Vasodilators or anti-anginal agents (such as nitric oxide, nitroglycerin)
- Other local anesthetic agents (such as bupivacine, proparacaine, ropivacine, mepivacaine, prilocaine, procaine, tetracaine)
- Antibiotics such as PABA, nitrofurantoin, dapsone, sulfasalazine
- Anticancer medicines such as cyclophosphamide, ifosfamide, hydroxyurea, flutamide, rasburicase
- Antimalarial agents (Ex. chloroquine, primaquine, quinine)
- Anti-epileptic agents (Ex. phenytoin, sodium valproate, phenobarbital)
- Metoclopramide (an antiemetic medicine)
Overdosage:
NYXOCAINE 2% JELLY is administered to you by a qualified healthcare provider. Therefore, it is unlikely to experience an overdosage. However, if you experience any unpleasant reactions, check with your doctor.
Synopsis
| Drug | : | Lignocaine |
| Pharmacological Category | : | Amide Local Anesthetics |
| Therapeutic Indication | : | Local anesthesia |
| Dosage Forms | : | Injection, Gel, Cream, Ointment, Jelly, Topical Solution, Spray, Oral solution, Plaster |
More Information
Storage
- Keep NYXOCAINE 2% JELLY out of reach of children
- Store NYXOCAINE 2% JELLY at room temperature
FAQs About NYXOCAINE 2% JELLY GEL
Q: How long will it take for NYXOCAINE 2% JELLY to induce numbness?
A: It may take around 3-5 minutes for NYXOCAINE 2% JELLY to create numbness. However, this period may vary from person-to-person based on the dose and amount of NYXOCAINE 2% JELLY that is administered.
Q: How long does the effects of NYXOCAINE 2% JELLY lasts long in the body?
A: The effects of NYXOCAINE 2% JELLY may last from 20-30 up to 1 hour after application. However, the recovery period may vary from person-to-person based on the dose and amount of the NYXOCAINE 2% JELLY applied.
Q: What is NYXOCAINE 2% JELLY used for?
A: NYXOCAINE 2% JELLY is a local anaesthetic medicine used as an anaesthetic lubricant prior to catheterization, tracheal intubation and diagnostic procedures (such as proctoscopy, rectoscopy, cystoscopy, gastroscopy, bronchoscopy, esophagoscopy etc.). It contains lignocaine (also known as lidocaine) which is a local anaesthetic that numbs the body sites where it has been applied. It can also provide temporary relief of pain and discomfort associated with cystitis and urethritis.
Q: How to use NYXOCAINE 2% JELLY?
A: NYXOCAINE 2% JELLY should be used under proper medical supervision. It is usually administered by the physician prior to the surgical or diagnostic procedures. However, it may also be self-administered by the patients if instructed by the doctor for temporary pain relief. Take a small quantity of NYXOCAINE 2% JELLY and apply on the required areas. Avoid contact of NYXOCAINE 2% JELLY with your eyes.
Q: Can NYXOCAINE 2% JELLY be used in children?
A: NYXOCAINE 2% JELLY can be used in children and adolescents (aged 2-18 years) if recommended by your physician. However, it should be used with extreme caution in infants aged 2 years or older and not suitable for use in infants aged below 1 year.
Q: How often can we use NYXOCAINE 2% JELLY?
A: NYXOCAINE 2% JELLY should be used as instructed by the doctor. Your doctor will decide the duration of therapy for you depending upon your age, body weight, health condition and sites where numbness is required in the body.
Q: Can NYXOCAINE 2% JELLY be used in infants?
A: NYXOCAINE 2% JELLY is not recommended for use in children aged below 2 years. Therefore, consult your doctor for advice.
Q: Will NYXOCAINE 2% JELLY cause sleepiness?
A: NYXOCAINE 2% JELLY may cause sleepiness when used more than the recommended dosage. It may also happen if you apply this medicine more frequently within a shorter duration. In such cases, consult your doctor for advice.
Q: What if I have accidental exposure of NYXOCAINE 2% JELLY to the eye?
A: Use lukewarm water to gently wash the outer surface of the eye in case of accidental contact with NYXOCAINE 2% JELLY. If the discomfort in the eye persists, contact your doctor, or visit a nearby hospital immediately.
Q: How NYXOCAINE 2% JELLY works?
A: NYXOCAINE 2% JELLY is a local anaesthetic agent. It reduces pain sensation and causes numbness of body parts by blocking the flow of certain ions (sodium ions) through the nerves that causes pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., face, hands, legs, abdomen, pelvis, genitals or where the medicine has been applied) to the brain which ultimately leads to loss of sensation.
References
- KD. Tripathi. Drugs acting on peripheral (somatic) nervous system. Essentials of medical pharmacology. 8th Edition. 2019. Page – 392.
- Natasha Beg, Thierry Vancaillie, Alan Hewitt, Julie Eggermont, Georgina Armstrong. NIH National Library of Medicine, National center for biotechnology information. Lignocaine gel in minimally invasive surgery - A pilot cohort, August 2010. [Accessed on 18th May 2024]. https://pubmed.ncbi.nlm.nih.gov/20716268/
- Pharmacy Retailing (NZ) Limited. Medsafe. [Revised in January 2018] Accessed on 18th May 2024]. https://www.medsafe.govt.nz/profs/Datasheet/x/Xylocainejelly.pdf
- Aspen Pharmacare Australia. Xylocaine 2% Jelly. [Accessed on 18th May 2024]. https://www.xylocaine.com.au/jelly/
- XYLOCAINE® JELLY 2%. Aspen Pharmacare Canada Inc. PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION. [Revied in September 2020]. [Accessed on 18th May 2024]. https://pdf.hres.ca/dpd_pm/00058090.PDF
- LIDOCAINE- lidocaine hydrochloride jelly. Akorn. Dailymed.com. [Revied in September 2022]. [Accessed on 18th May 2024]. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=317a8784-5fdd-429f-9b74-14d89f372a32&type=display
Useful Diagnostic Tests
- Healthy Midlife Checkup
- Full Body Checkup – Gold
- Full Body Checkup - Silver
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